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Matteo Giovanni Carrabba, MD
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Journal Articles

Immune Senescence and Exhaustion Correlate with Response to Flotetuzumab, an Investigational CD123×CD3 Bispecific Dart® Molecule, in Acute Myeloid Leukemia

Jayakumar Vadakekolathu, PhD, Tung On Yau, Sarah E. Church, PhD, Michael P. Rettig, PhD, Ibrahim Aldoss, MD, Geoffrey L Uy, MD, Norbert Vey, MD, Ashkan Emadi, MD, PhD, Peter H. Sayre, MDPhD, Roland B. Walter, MDPhDMS, Matthew C Foster, MD, Martha L. Arellano, MD, John E. Godwin, MD, Matthew J. Wieduwilt, MD PhD, Michael T. Byrne, DO, Laura C. Michaelis, MD, Patrick J. Stiff, MD, Matteo Giovanni Carrabba, MD, Patrice Chevalier, MD PhD, Emmanuel Gyan, MD PhD, Christian Recher, MD PhD, Anjali S Advani, MD, Martin Wermke, Harry P. Erba, Fabio Ciceri, MD, Geert Huls, MD PhD, Mojca Jongen-Lavrencic, MD PhD, Farhad Ravandi, MBBS, Antonio Curti, MDPhD, Max S. Topp, MD, John Muth, MS, Patrick Kaminker, PhD, Bob Lowenberg, MDPhD, Ivana Gojo, MD, Leo Luznik, MD, John F. DiPersio, MD PhD, Jan K Davidson-Moncada, MDPhD, Sergio Rutella, MDPhDFRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–28.
https://doi.org/10.1182/blood-2020-134921
Published: 2020
Journal Articles

Prophylactic Ruxolitinib for Cytokine Release Syndrome (CRS) in Relapse/Refractory (R/R) AML Patients Treated with Flotetuzumab

Geoffrey L Uy, MD, Michael P. Rettig, PhD, Stephanie Christ, MS, Ibrahim Aldoss, MD, Michael T. Byrne, DO, Harry P. Erba, MD PhD, Martha L. Arellano, MD, Matthew C Foster, MD, John E. Godwin, MD, Farhad Ravandi, MBBS, Peter H. Sayre, MDPhD, Anjali S Advani, MD, Matthew J. Wieduwilt, MD PhD, Ashkan Emadi, MD, PhD, Laura C. Michaelis, MD, Patrick J. Stiff, MD, Martin Wermke, Norbert Vey, MD, Patrice Chevalier, MD PhD, Emmanuel Gyan, MD PhD, Christian Recher, MD PhD, Fabio Ciceri, MD, Matteo Giovanni Carrabba, MD, Antonio Curti, MDPhD, Geert Huls, MD PhD, Max S. Topp, MD, Mojca Jongen-Lavrencic, MD PhD, John Muth, MS, Teia Curtis, Mary Beth Collins, Erin Timmeny, Kuo Guo, MSc, Jian Zhao, PhD, Kathy Tran, Patrick Kaminker, PhD, Priyanka Patel, PharmD, Ouiam Bakkacha, MD, Kenneth Jacobs, MD, Maya Kostova, PhD, Jennifer Seiler, PhD RAC, Bob Lowenberg, MDPhD, Sergio Rutella, MDPhDFRCPath, Roland B. Walter, MDPhDMS, Ezio Bonvini, MD, Jan K Davidson-Moncada, MDPhD, John F. DiPersio, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–21.
https://doi.org/10.1182/blood-2020-134612
Published: 2020
Journal Articles

Checkpoint Inhibition before Axicabtagene Ciloleucel Cell Therapy in Primary Mediastinal B-Cell Lymphoma (PMBCL) Treated in Real Life Setting

Annalisa Chiappella, Anna Dodero, Anna Guidetti, Filippo Bagnoli, MD, Vanessa Aragona, Anna Maria Barbui, MD, Stefania Bramanti, MD, Matteo Giovanni Carrabba, MD, Federica Sorà, MD, Pierluigi Zinzani, Prof, MD, Chiara Monfrini, Cristiana Carniti, Paolo Corradini
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-140054
Published: 2020
Journal Articles

TP53 Abnormalities Correlate with Immune Infiltration and Associate with Response to Flotetuzumab Immunotherapy in Acute Myeloid Leukemia

Catherine Lai, MD MPH, Jayakumar Vadakekolathu, PhD, Stephen Reeder, BSc, Sarah E. Church, PhD, Carmen Ballesteros-Merino, PhD, Ibrahim Aldoss, MD, Anjali S Advani, MD, John E. Godwin, MD, Matthew J. Wieduwilt, MD PhD, Martha L. Arellano, MD, Geoffrey L Uy, MD, Farhad Ravandi, MBBS, Matthew C Foster, MD, Emmanuel Gyan, MD PhD, Patrick J. Stiff, MD, Norbert Vey, MD, Ashkan Emadi, MD, PhD, Matteo Giovanni Carrabba, MD, Roland B. Walter, MDPhDMS, Peter H. Sayre, MDPhD, Kathy Tran, Erin Timmeny, Michael P. Rettig, PhD, Patrick Kaminker, PhD, John Muth, MS, Kuo Guo, MSc, Tung On Yau, Peter J.M. Valk, PhD, Bob Lowenberg, MDPhD, Ivana Gojo, MD, Martin Bornhäuser, MD, John F. DiPersio, MD PhD, Jan K Davidson-Moncada, MDPhD, Sergio Rutella, MDPhDFRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-136919
Published: 2020
Journal Articles

Flotetuzumab As Salvage Therapy for Primary Induction Failure and Early Relapse Acute Myeloid Leukemia

Ibrahim Aldoss, MD, Geoffrey L Uy, MD, Norbert Vey, MD, Ashkan Emadi, MD, PhD, Peter H. Sayre, MDPhD, Roland B. Walter, MDPhDMS, Matthew C Foster, MD, Martha L. Arellano, MD, John E. Godwin, MD, Matthew J. Wieduwilt, MD PhD, Michael T. Byrne, DO, Laura C. Michaelis, MD, Patrick J. Stiff, MD, Matteo Giovanni Carrabba, MD, Patrice Chevalier, MD PhD, Emmanuel Gyan, MD PhD, Christian Recher, MD PhD, Anjali S Advani, MD, Martin Wermke, Harry P. Erba, Fabio Ciceri, MD, Geert Huls, MD PhD, Mojca Jongen-Lavrencic, MD PhD, Max S. Topp, MD, Antonio Curti, MDPhD, Farhad Ravandi, MBBS, Michael P. Rettig, PhD, John Muth, MS, Mary Beth Collins, Erin Timmeny, Kuo Guo, MSc, Jian Zhao, PhD, Kathy Tran, Patrick Kaminker, PhD, Priyanka Patel, PharmD, Ouiam Bakkacha, MD, Teia Curtis, Kenneth Jacobs, MD, Maya Kostova, PhD, Jennifer Seiler, PhD RAC, Bob Lowenberg, MDPhD, Sergio Rutella, MDPhDFRCPath, Ezio Bonvini, MD, Jan K Davidson-Moncada, MDPhD, John F. DiPersio, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–18.
https://doi.org/10.1182/blood-2020-134576
Published: 2020
Journal Articles

Exploiting an Anti-CD3/CD33 Bispecific Antibody to Redirect Donor T Cells Against HLA Loss Leukemia Relapses

Pier Edoardo Rovatti, MD, Laura Zito, MSc, Eleonora Draghi, MSc, Monika Herrmann, PhD, Anetta Marcinek, MSc, Bettina Brauchle, MSc, Cesare Covino, MSc, Mattia Di Bono, MSc, Matteo Giovanni Carrabba, MD, Massimo Bernardi, MD, Karl-Peter Hopfner, PhD, Cristina Toffalori, PhD, Fabio Ciceri, MD, Marion Subklewe, MD, Luca Vago, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 513.
https://doi.org/10.1182/blood-2019-126641
Published: 2019
Journal Articles

Mapping the Evolution of the Mutational Landscape of Acute Myeloid Leukemia from Diagnosis to Post-Transplantation Relapse and Its Interplay with Immune Evasion Mechanisms

Elisa Sala, MD, Francesca Biavasco, MD, Gabriele Bucci, PhD, Cristina Toffalori, PhD, Donatella Biancolini, PhD, Elena Antonini, MSc, Matteo Giovanni Carrabba, MD, Bernhard Gentner, MD, Cristina Tresoldi, MSc, Massimo Bernardi, MD, Dejan Lazarevic, MD, Giovanni Tonon, MD, Fabio Ciceri, MD, Luca Vago, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 511.
https://doi.org/10.1182/blood-2019-124725
Published: 2019
Journal Articles

TEM-MM-101: A Phase I/IIa Dose Escalation Study Evaluating the Safety and Activity of Autologous CD34+ Enriched Hematopoietic Progenitor Cells Genetically Modified for Human Interferon-α2 in Multiple Myeloma Patients with Early Relapse after Intensive Front Line Therapy

Bernhard Gentner, MD, Francesca Farina, MD, Matteo Giovanni Carrabba, MD, Magda Marcatti, MD, Stefania Girlanda, MD, Gabriele Antonarelli, MD, Capotondo Alessia, PhD, Stefania Mazzoleni, PhD, Carlo Russo, MD, Luigi Naldini, MD PhD, Fabio Ciceri, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2064.
https://doi.org/10.1182/blood-2019-123749
Published: 2019
Journal Articles

Improvement in Cytokine Release Syndrome Management for the Treatment of AML Patients with Flotetuzumab, a CD123 x CD3 Bispecific Dart® Molecule for T-Cell Redirected Therapy

Ouiam Bakkacha, MD, Geoffrey L. Uy, MD, Ibrahim Aldoss, MD, Matthew C Foster, MD, David A Sallman, MD, Kendra L. Sweet, MD, David A. Rizzieri, MD, Peter H. Sayre, MD PhD, Anjali S. Advani, MD, Ashkan Emadi, MD, Matthew J. Wieduwilt, MD PhD, Norbert Vey, MD PhD, Fabio Ciceri, MD, Matteo Giovanni Carrabba, MD, Tamara Moyo, MD PhD, Martha L. Arellano, MD, John E. Godwin, MD, Bob Löwenberg, MD PhD, Gerwin Huls, MD PhD, Farhad Ravandi, MD, Kathy Tran, John Muth, MS, Jan Baughman, MPH, Mojca Jongen-Lavrencic, MD PhD, Erin Timmeny, Max S. Topp, MD, Stefania Paolini, MD PhD, Kuo Guo, MSc, Teia Curtis, Jian Zhao, PhD, Jon Wigginton, MD, Ezio Bonvini, MD, Roland B. Walter, MD PhD MS, Jan Davidson, John F. DiPersio, MD PhD, Kenneth Jacobs, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5144.
https://doi.org/10.1182/blood-2019-127138
Published: 2019
Journal Articles

Flotetuzumab, an Investigational CD123 x CD3 Bispecific Dart® Protein, in Salvage Therapy for Primary Refractory and Early Relapsed Acute Myeloid Leukemia (AML) Patients

Geoffrey L. Uy, MD, Ibrahim Aldoss, MD, Matthew C Foster, MD, David A Sallman, MD, Kendra L. Sweet, MD, David A. Rizzieri, MD, Peter H. Sayre, MD PhD, Anjali S. Advani, MD, Ashkan Emadi, MD, Matthew J. Wieduwilt, MD PhD, Norbert Vey, MD PhD, Fabio Ciceri, MD, Matteo Giovanni Carrabba, MD, Tamara Moyo, MD PhD, Sarah E. Church, PhD, Michael P. Rettig, PhD, Martha L. Arellano, MD, John E. Godwin, MD, Bob Löwenberg, MD PhD, Gerwin Huls, MD PhD, Farhad Ravandi, MD, John Muth, MS, Kathy Tran, Mojca Jongen-Lavrencic, MD PhD, Erin Timmeny, Max S. Topp, MD, Stefania Paolini, MD PhD, Kuo Guo, MSc, Teia Curtis, Jian Zhao, PhD, Jayakumar Vadakekolathu, PhD, Jon M. Wigginton, MD, Ezio Bonvini, MD, Sergio Rutella, MDPhDFRCPath, Roland B. Walter, MD PhD MS, Jan K Davidson-Moncada, MD PhD, John F. DiPersio, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 733.
https://doi.org/10.1182/blood-2019-122073
Published: 2019
Journal Articles

Management of Cytokine Release Syndrome in AML Patients Treated with Flotetuzumab, a CD123 x CD3 Bispecific Dart ® Molecule for T-Cell Redirected Therapy

Kenneth Jacobs, MD, Cedric Viero, PhD, John Godwin, MD, Jan Baughman, MPH, Jichao Sun, PhD, Kang Ying, John Muth, MS, Shengyan Hong, PhD, Norbert Vey, MD PhD, Kendra L. Sweet, MD, Geoffrey L. Uy, MD, Farhad Ravandi, MD, Matthew C Foster, MD, David A. Rizzieri, MD, Martha L. Arellano, MD, Michael P. Rettig, PhD, Max S. Topp, Gerwin Huls, MD PhD, Helene Lelièvre, PhD PharmD, Stefania Paolini, MD PhD, Fabio Ciceri, MD, Matteo Giovanni Carrabba, MD, Bob Lowenberg, MD, John F. DiPersio, MD PhD, Jon Wigginton, MD, Jan K Davidson-Moncada, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2738.
https://doi.org/10.1182/blood-2018-99-112615
Published: 2018
Journal Articles

Combining Whole Exome Sequencing and Rnaseq to Provide a Comprehensive Landscape of the Mechanisms of Post-Transplantation Leukemia Relapse

Lucia Zanotti, PhD, Gabriele Bucci, PhD, Francesco Santaniello, Cristina Toffalori, Donatella Biancolini, PhD, Ettore Zapparoli, Laura Zito, Matteo Giovanni Carrabba, MD, Friedrich Stoelzel, Martin Bornhäuser, Massimo Bernardi, MD, Jacopo Peccatori, Chiara Bonini, MD, Davide Cittaro, PhD, Dejan Lazarevic, Giovanni Tonon, MD PhD, Fabio Ciceri, MD, Luca Vago, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 819.
https://doi.org/10.1182/blood-2018-99-111769
Published: 2018
Journal Articles

Immune Reconstitution Is a Predictive Biomarker of Chronic Graft-Versus-Host Disease: Analysis of 307 Consecutive Patients

Fabio Serpenti, Francesca Lorentino, Raffaella Milani, Raffaella Greco, MD, Andrea Assanelli, MD, Carlo Messina, MD, Sara Mastaglio, MD, Fabio Giglio, MD, Francesca Pavesi, MD, Francesca Farina, MD, Sarah Marktel, MD, Magda Marcatti, MD, Francesca Lunghi, Elena Guggiari, MD, Matteo Giovanni Carrabba, MD, Consuelo Corti, MD, Massimo Bernardi, MD, Jacopo Peccatori, Chiara Bonini, MD, Fabio Ciceri, MD, Maria Teresa Lupo Stanghellini
Journal: Blood
Blood (2018) 132 (Supplement 1): 4579.
https://doi.org/10.1182/blood-2018-99-113855
Published: 2018
Journal Articles

Phase I-IIa Clinical Trial to Assess Safety and Efficacy of MLM-CAR44.1, a CD44v6 Directed CAR-T in Relapsed/Refractory Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Matteo Giovanni Carrabba, MD, Monica Casucci, PhD, Michael Hudecek, MD, Concetta Quintarelli, PhD, Javier Briones, MD, Roman Hajek, MD PhD, Jorge Sierra, MD, Franco Locatelli, Hermann Einsele, MD PhD, Claudio Bordignon, MD, Fabio Ciceri, MD, Catia Traversari, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5790.
https://doi.org/10.1182/blood-2018-99-117974
Published: 2018
Journal Articles

Phase 1 Cohort Expansion of Flotetuzumab, a CD123×CD3 Bispecific Dart ® Protein in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Geoffrey L. Uy, MD, Michael P. Rettig, PhD, Norbert Vey, MD PhD, John Godwin, MD, Matthew C Foster, MD, David A. Rizzieri, MD, Martha L. Arellano, MD, Max S. Topp, Gerwin Huls, MD PhD, Mojca Jongen-Lavrencic, MD PhD, Giovanni Martinelli, MD, Stefania Paolini, MD PhD, Fabio Ciceri, MD, Matteo Giovanni Carrabba, MD, Kendra L. Sweet, MD, Farhad Ravandi, MD, Sarah E. Church, PhD, Jayakumar Vadakekolathu, PhD, Sergio Rutella, MD PhD FRCPath, Jichao Sun, PhD, Kang Yang, Jan Baughman, MPH, Teia Curtis, PhD, Erin Timmeny, Kerri Cali, Kathy Tran, John Muth, MS, Ross La Motte-Mohs, PhD, Camille Poirot, Pharm.D., Athanasios Pallis, MD, Alessandra Cesano, MD PhD, Ezio Bonvini, MD, Jon Wigginton, MD, Bob Lowenberg, MD, Jan K Davidson-Moncada, MD PhD, John F. DiPersio, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 764.
https://doi.org/10.1182/blood-2018-99-117085
Published: 2018
Journal Articles

Preliminary Results of a Phase 1 Study of Flotetuzumab, a CD123 x CD3 Bispecific Dart® Protein, in Patients with Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome

Geoffrey L. Uy, MD, John Godwin, MD, Michael P Rettig, PhD, Norbert Vey, Matthew Foster, Martha L. Arellano, MD, David A. Rizzieri, MD, Max S. Topp, MD, Gerwin Huls, MD PhD, Bob Lowenberg, MD PhD, Giovanni Martinelli, MD, Stefania Paolini, MD PhD, Fabio Ciceri, MD, Matteo Giovanni Carrabba, MD, Carmen Ballesteros-Merino, PhD, Carlo B Bifulco, MD, Helene Lelièvre, PhD PharmD, Ross La Motte-Mohs, PhD, Daner Li, MS, Jichao Sun, PhD, Kenneth Jacobs, MD, Karen Spohn, BS, Nadia Lonsdale, BA, Kathy Tran, Jan Baughman, MPH, Michele Shannon, PhD, Bernard Fox, PhD, Ezio Bonvini, MD, Jon Wigginton, Jan Davidson-Moncada, MD, John F DiPersio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 637.
https://doi.org/10.1182/blood.V130.Suppl_1.637.637
Published: 2017
Journal Articles

Lead-in Dose Optimization to Mitigate Cytokine Release Syndrome in AML and MDS Patients Treated with Flotetuzumab, a CD123 x CD3 Dart® Molecule for T-Cell Redirected Therapy

Kenneth Jacobs, MD, John Godwin, MD, Matthew Foster, Norbert Vey, Geoffrey L. Uy, MD, David A. Rizzieri, MD, Martha L. Arellano, MD, Michael P Rettig, PhD, Stephanie Christ, MS, Max S. Topp, MD, Geert Huls, MD PhD, Bob Lowenberg, MD PhD, Giovanni Martinelli, MD, Stefania Paolini, MD PhD, Fabio Ciceri, MD, Matteo Giovanni Carrabba, MD, Jichao Sun, PhD, Daner Li, MS, Kathy Tran, Karen Spohn, BS, Jan Baughman, MPH, Sadhna Shankar, MDMPH, Helene Lelièvre, PhD PharmD, Ezio Bonvini, MD, John F DiPersio, MD PhD, Jon Wigginton, Jan K davidson-Moncada, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3856.
https://doi.org/10.1182/blood.V130.Suppl_1.3856.3856
Published: 2017
Journal Articles

cGvHD — CIBMTR Risk Score Stratification in 207 Consecutive Adults after Unmanipulated PBSC Haploidentical Stem Cell Transplantation

Maria Teresa Lupo Stanghellini, MD, Francesca Lorentino, MD, Gabriele Antonarelli, Elisa Sala, MD, Raffaella Greco, MD, Mara Morelli, MD, Magda Marcatti, MD, Simona Piemontese, MD, Andrea Assanelli, MD, Matteo Giovanni Carrabba, MD, Fabio Serpenti, Fabio Giglio, MD, Sara Mastaglio, MD, Sarah Marktel, MD, Francesca Lunghi, MD, Elena Guggiari, MD, Francesca Pavesi, MD, Luca Vago, MD PhD, Consuelo Corti, MD, Massimo Bernardi, MD, Jacopo Peccatori, MD, Fabio Ciceri, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4499.
https://doi.org/10.1182/blood.V130.Suppl_1.4499.4499
Published: 2017
Journal Articles

Direct Costs in 4-Years Post Allogeneic Transplant Follow-up: A Comparative Analysis of 15 Matched Patients with and without GvHD

Maria Teresa Lupo Stanghellini, MD, Elisabetta Xue, MD, Raffaella Greco, MD, Elena Guggiari, MD, Andrea Assanelli, MD, Daniele Mannina, MD, Sarah Marktel, MD, Magda Marcatti, MD, Matteo Giovanni Carrabba, MD, Francesca Lunghi, MD, Mara Morelli, MD, Tommaso Perini, MD, Gabriele Casirati, MD, Carlo Messina, MD, Simona Piemontese, MD, Fabio Giglio, MD, Luca Vago, MD PhD, Massimo Bernardi, MD, Consuelo Corti, MD, Jacopo Peccatori, MD, Fabio Ciceri, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5488.
https://doi.org/10.1182/blood.V130.Suppl_1.5488.5488
Published: 2017
Journal Articles

Longitudinal Microbiome Profile in Allogeneic Hematopoietic Stem Cell Transplantation: Results of a Prospective Study in 100 Patients

Raffaella Greco, MD, Nicasio Mancini, MD, Renée Pasciuta, Maria Chiara Barbanti, MD, Mara Morelli, MD, Luca Vago, MD PhD, Fabio Giglio, MD, Maria Teresa Lupo Stanghellini, MD, Alessandra Forcina, MD, Laura Infurnari, Sarah Marktel, MD, Andrea Angelo Assanelli, MD, Matteo Giovanni Carrabba, MD, Massimo Bernardi, MD, Consuelo Corti, MD, Jacopo Peccatori, MD, Massimo Clementi, MD, Fabio Ciceri, MD
Journal: Blood
Blood (2016) 128 (22): 3435.
https://doi.org/10.1182/blood.V128.22.3435.3435
Published: 2016