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Journal Articles

Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia

Alessandro Coppe, BSc, PhD, Emma I Andersson, MSc, Andrea Binatti, BSc, Vanessa R Gasparini, Sabrina Bortoluzzi, Michael J. Clemente, M.S., Marco Herling, MD PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Satu Mustjoki, MD PhD, Stefania Bortoluzzi, BSc, PhD

Blood (2016) 128 (22): 4117.

https://doi.org/10.1182/blood.V128.22.4117.4117

Published: 2016

Journal Articles

Next-Generation Sequencing Analysis of Clonal Hierarchy and Dynamics in T-Large Granular Lymphocyte Leukemia Suggests Emergence of STAT3 Clones within Pre-Existing Dominant T-Cell Repertoire Responses Otherwise Silenced in Normal Individuals

Peter W Chomczynski, Michael J. Clemente, M.S., Srinivasa Reddy Sanikommu, MD, Alek d Nielsen, B.S., Cassandra M. Hirsch, BSc, Hanna Rajala, MD, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Satu Mustjoki, MD PhD, Alan E. Lichtin, MD, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 2731.

https://doi.org/10.1182/blood.V128.22.2731.2731

Published: 2016

Journal Articles

PHF6 Somatic Mutations and Their Functional Role in the Pathophysiology of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Bartlomiej P Przychodzen, MSc, Xiaorong Gu, PhD, Dewen You, PhD, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Mikkael A. Sekeres, MD MS, Aziz Nazha, MD, Hideki Makishima, MD PhD FACP., Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 2736.

https://doi.org/10.1182/blood.V128.22.2736.2736

Published: 2016

Journal Articles

Subcutaneous Low Dose Alemtuzumab: Role As a Salvage Therapy in Immune -Mediated Marrow Failure Conditions

Swapna Thota, MD, Srinivasa Reddy Sanikommu, MD, Bhumika Patel, MD, Meena Sadaps, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Serena Marotta, MD, Antonio M Risitano, MD PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1505.

https://doi.org/10.1182/blood.V128.22.1505.1505

Published: 2016

Journal Articles

Clonal Hierarchy of Piga Mutant Cells Assessed By Next Generation Sequencing Is More Complex Than Previously Recognized in Paroxysmal Noctural Hemoglobinuria

Michael J. Clemente, M.S., Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1506.

https://doi.org/10.1182/blood.V128.22.1506.1506

Published: 2016

Journal Articles

UTX mutations in Myeloid Neoplasms

Yasunobu Nagata, MD,PhD, Tomas Radivoyevitch, PhD, Hideki Makishima, MD PhD FACP., Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Teodora Kuzmanovic, BSc, Eiju Negoro, MD, PhD, Michael J. Clemente, M.S., Sudipto Mukherjee, MD, PhD, M.P.H., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3148.

https://doi.org/10.1182/blood.V128.22.3148.3148

Published: 2016

Journal Articles

U2AF1 Mutations in S34 and Q157 Create Distinct Molecular and Clinical Contexts

Vera Adema, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Aziz Nazha, MD, Teodora Kuzmanovic, Eiju Negoro, MD, PhD, Dewen You, PhD, Hideki Makishima, MD PhD FACP., Michael J. Clemente, M.S., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 3155.

https://doi.org/10.1182/blood.V128.22.3155.3155

Published: 2016

Journal Articles

Using Machine Intelligence Algorithms to Develop a Geno-Clinical Model to Predict Responses to Hypomethylating Agents in Myelodysplastic Syndromes

Aziz Nazha, MD, Mikkael A. Sekeres, MD MS, Rafael Bejar, MD PhD, John Barnard, PhD, Karam Al-Issa, MD, Bartlomiej P Przychodzen, MSc, Matt Kalaycio, MD, Michael J. Clemente, M.S., Cassandra M. Hirsch, BSc, Benjamin L Ebert, MD PhD, Jaroslaw P. Maciejewski

Blood (2016) 128 (22): 3193.

https://doi.org/10.1182/blood.V128.22.3193.3193

Published: 2016

Journal Articles

Clonal Dynamics of Refractory Aplastic Anemia in Patients Treated with Eltrombopag

Bhumika Patel, MD, Bartlomiej P Przychodzen, MSc, Michael J. Clemente, M.S., Cassandra M. Hirsch, BSc, Caner Saygin, MD, Marissa Versalle, MD, Swapna Thota, MD, Aziz Nazha, MD, Roy Souaid, MD, Valeria Visconte, PhD, Taha Bat, MD, Suresh Kumar Balasubramanian, MD, Tomas Radivoyevitch, PhD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3892.

https://doi.org/10.1182/blood.V128.22.3892.3892

Published: 2016

Journal Articles

BCOR and BCORL1 mutations in Myelodysplastic Syndromes (MDS): Clonal Architecture and Impact on Outcomes

Nour Abuhadra, MD, Karam Al-Issa, MD, Aaron T. Gerds, MD MS, Sudipto Mukherjee, MD, PhD, M.P.H., Bhumika Patel, MD, Michael J. Clemente, M.S., Vera Adema, PhD, Cassandra M. Hirsch, BSc, Anjali S. Advani, MD, Mai Aly, Przychodzen P Bartlomiej, Hetty E. Carraway, MD, Jaroslaw P Maciejewski, MD PhD FACP, Mikkael A. Sekeres, MD MS, Aziz Nazha, MD

Blood (2016) 128 (22): 4293.

https://doi.org/10.1182/blood.V128.22.4293.4293

Published: 2016

Journal Articles

Targeting Autophagy in Myelodysplastic Syndromes

Valeria Visconte, PhD, Steffan T. Nawrocki, PhD, Bartlomiej P Przychodzen, MSc, Kevin R. Kelly, MD PhD, Mei Yin, Yvonne Parker, Michael J. Clemente, M.S., John Barnard, PhD, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Daniel Lindner, Heesun J Rogers, MD PhD, Jaroslaw P Maciejewski, MD PhD FACP, Jennifer S. Carew, PhD

Blood (2016) 128 (22): 4295.

https://doi.org/10.1182/blood.V128.22.4295.4295

Published: 2016

Journal Articles

TP53 Mutations and Outcome in Patients with Myelodysplastic Syndromes (MDS)

Karam Al-Issa, MD, Mikkael A. Sekeres, MD MS, Alek d Nielsen, B.S., Babal Jha, PhD, Bartlomiej P Przychodzen, MSc, Mai Aly, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Bhumika Patel, MD, Michael J. Clemente, M.S., Sudipto Mukherjee, MD, PhD, M.P.H., Aaron T. Gerds, MD MS, Jaroslaw P Maciejewski, MD PhD FACP, Aziz Nazha, MD

Blood (2016) 128 (22): 4336.

https://doi.org/10.1182/blood.V128.22.4336.4336

Published: 2016

Journal Articles

Impact of Erythropoietic Stimulating Agents on Mutational Composition in Patients with Low-Risk Myelodysplastic Syndromes

Bhumika Patel, MD, Caner Saygin, MD, Bartlomiej P Przychodzen, MSc, Teodora Kuzmanovic, BSc, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Swapna Thota, MD, Aziz Nazha, MD, Sekeres A Mikkael, MD, Jaroslaw P Maciejewski, MD PhD FACP, Hetty E. Carraway, MD MBA

Blood (2016) 128 (22): 2002.

https://doi.org/10.1182/blood.V128.22.2002.2002

Published: 2016

Journal Articles

Incorporation of Molecular Data into the Current Prognostic Models in Treated Patients with Myelodysplastic Syndromes: Which Model Is the Best

Karam Al-Issa, MD, Ahmad Zarzour, MD, Tomas Radivoyevitch, PhD, Matt Kalaycio, MD, Betty K. Hamilton, MD, Aaron T. Gerds, MD MS, Sudipto Mukherjee, MD, PhD, M.P.H., Vera Adema, PhD, Michael J. Clemente, M.S., Bhumika Patel, MD, Cassandra M. Hirsch, BSc, Anjali S. Advani, MD, Bartlomiej P Przychodzen, MSc, Hetty E. Carraway, MD MBA, Jaroslaw P Maciejewski, MD PhD FACP, Mikkael A. Sekeres, MD MS, Aziz Nazha, MD

Blood (2016) 128 (22): 50.

https://doi.org/10.1182/blood.V128.22.50.50

Published: 2016

Journal Articles

The Mechanism By Which Mutant Nucleophosmin (NPM1) Creates Leukemic Self-Renewal Is Readily Reversed

Xiaorong Gu, PhD, Reda Z. Mahfouz, MD, PhD, Quteba Ebrahem, Francis Enane, Tomas Radivoyevitch, PhD, Michael J. Clemente, M.S., Bartlomiej P Przychodzen, MSc, Zhenbo Hu, MD PhD, Ramesh Balusu, PhD, Claudiu V. Cotta, MD, David N. Wald, MDPhD, Yosef Landesman, PhD, Maria Paola Martelli, MD PhD, Brunangelo Falini, Jaroslaw P Maciejewski, MD PhD FACP, Yogenthiran Saunthararajah, MD

Blood (2016) 128 (22): 444.

https://doi.org/10.1182/blood.V128.22.444.444

Published: 2016

Journal Articles

Molecular and Immunophenotypic Characteristics of Adult Acute Leukemias of Ambiguous Lineage

Bhumika Patel, MD, Caner Saygin, MD, Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Betty K. Hamilton, MD, Anjali S. Advani, MD, Aziz Nazha, MD, Sarah Lynn Ondrejka, DO, Matt Kalaycio, MD, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1659.

https://doi.org/10.1182/blood.V128.22.1659.1659

Published: 2016

Journal Articles

Landscape of Subclonal Mutations in Myelodysplastic Syndromes (MDS) Allows for a Novel Hierarchy of Clonal Advantage By Combining Germline and Somatic Mutations

Blood (2016) 128 (22): 957.

https://doi.org/10.1182/blood.V128.22.957.957

Published: 2016

NARROW

Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia

Next-Generation Sequencing Analysis of Clonal Hierarchy and Dynamics in T-Large Granular Lymphocyte Leukemia Suggests Emergence of STAT3 Clones within Pre-Existing Dominant T-Cell Repertoire Responses Otherwise Silenced in Normal Individuals

PHF6 Somatic Mutations and Their Functional Role in the Pathophysiology of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Subcutaneous Low Dose Alemtuzumab: Role As a Salvage Therapy in Immune -Mediated Marrow Failure Conditions

Clonal Hierarchy of Piga Mutant Cells Assessed By Next Generation Sequencing Is More Complex Than Previously Recognized in Paroxysmal Noctural Hemoglobinuria

UTX mutations in Myeloid Neoplasms

U2AF1 Mutations in S34 and Q157 Create Distinct Molecular and Clinical Contexts

Using Machine Intelligence Algorithms to Develop a Geno-Clinical Model to Predict Responses to Hypomethylating Agents in Myelodysplastic Syndromes

Clonal Dynamics of Refractory Aplastic Anemia in Patients Treated with Eltrombopag

BCOR and BCORL1 mutations in Myelodysplastic Syndromes (MDS): Clonal Architecture and Impact on Outcomes

Targeting Autophagy in Myelodysplastic Syndromes

TP53 Mutations and Outcome in Patients with Myelodysplastic Syndromes (MDS)

Impact of Erythropoietic Stimulating Agents on Mutational Composition in Patients with Low-Risk Myelodysplastic Syndromes

Incorporation of Molecular Data into the Current Prognostic Models in Treated Patients with Myelodysplastic Syndromes: Which Model Is the Best

The Mechanism By Which Mutant Nucleophosmin (NPM1) Creates Leukemic Self-Renewal Is Readily Reversed

Molecular and Immunophenotypic Characteristics of Adult Acute Leukemias of Ambiguous Lineage

Landscape of Subclonal Mutations in Myelodysplastic Syndromes (MDS) Allows for a Novel Hierarchy of Clonal Advantage By Combining Germline and Somatic Mutations

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American Society of Hematology

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American Society of Hematology

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