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Journal Articles

The Regulatory Function Of Amino Acid Region 473-487 Of Prothrombin During Coagulation

Joesph R Wiencek, BA, Michael Kalafatis, PhD

Blood (2013) 122 (21): 3574.

https://doi.org/10.1182/blood.V122.21.3574.3574

Published: 2013

Journal Articles

Cleavage At Arg1018 During Thrombin-Mediated Activation of Coagulation Factor V Is Dispensable

Mahesheema Na, MSc, Joesph R Wiencek, B.A., Jamila Hirbawi, PhD, Michael Kalafatis, PhD

Blood (2011) 118 (21): 1186.

https://doi.org/10.1182/blood.V118.21.1186.1186

Published: 2011

Journal Articles

The Role of Amino Acids 700–701 of the Factor Va Heavy Chain During Prothrombin Activation by Factor Xa

Jamila Hirbawi, PhD, Paul Y Kim, PhD, Michael E. Nesheim, PhD, Michael Kalafatis, PhD

Blood (2010) 116 (21): 2203.

https://doi.org/10.1182/blood.V116.21.2203.2203

Published: 2010

Journal Articles

Amino Acid Region 1000–1008 of Coagulation Factor V Is a Dynamic Regulator for the Emergence of Procoagulant Activity

Joesph R Wiencek, B.A., Jamila Hirbawi, PhD, Mahesheema Na, Michael Kalafatis, PhD

Blood (2010) 116 (21): 2221.

https://doi.org/10.1182/blood.V116.21.2221.2221

Published: 2010

Journal Articles

Role of the N-Terminal Amino Acid Region of Factor Va Light Chain In Prothrombinase Assembly and Function.

John L. Vaughn, BS, Jamila Hirbawi, PhD, Michael A. Bukys, PhD, Michael Kalafatis, PhD

Blood (2010) 116 (21): 1127.

https://doi.org/10.1182/blood.V116.21.1127.1127

Published: 2010

Journal Articles

The Role of Amino Acids 659-663 of Factor Va Heavy Chain During Prothrombin Activation by Prothrombinase.

Jamila Hirbawi, BS, Michael Kalafatis, PhD

Blood (2009) 114 (22): 2131.

https://doi.org/10.1182/blood.V114.22.2131.2131

Published: 2009

Journal Articles

Amino Acids Asp695 and Tyr696 of Factor Va Are Essential for Optimal Rate of Prothrombin Activation by Prothrombinase.

Jamila Hirbawi, BS, Michael Kalafatis, PhD

Blood (2009) 114 (22): 3163.

https://doi.org/10.1182/blood.V114.22.3163.3163

Published: 2009

Journal Articles

Casein Kinase CK2 Inhibition Results in Tumor Suppression.

Hanan Mohammad, B.S., Daniel j Lindner, M.D., Ph.D., Michael Kalafatis, PhD

Blood (2009) 114 (22): 5052.

https://doi.org/10.1182/blood.V114.22.5052.5052

Published: 2009

Journal Articles

The Effect of Factor Va on Prothrombinase Function

Michael Kalafatis, PhD, Jamila Hirbawi, BS, Melissa A. Barhoover, PhD, Michael A. Bukys, PhD

Blood (2008) 112 (11): 1020.

https://doi.org/10.1182/blood.V112.11.1020.1020

Published: 2008

Journal Articles

The Acidic COOH-Terminal Region of Factor Va Heavy Chain Controls the Rate of Prothrombin Activation by Prothrombinase.

Jamila Hirbawi, BS, Michael A. Bukys, BS, Melissa A. Barhoover, BS, Michael Kalafatis, PhD

Blood (2007) 110 (11): 1745.

https://doi.org/10.1182/blood.V110.11.1745.1745

Published: 2007

Journal Articles

Understanding the Factor Va Cofactor Effect within Prothrombinase.

Michael Kalafatis, PhD, Michael A. Bukys, BS, Jamila Hirbawi, BS, Paul Y. Kim, BS, Melissa A. Barhoover, BS, Michael E. Nesheim, PhD

Blood (2007) 110 (11): 2700.

https://doi.org/10.1182/blood.V110.11.2700.2700

Published: 2007

Journal Articles

Factor Va Cofactor Activity Is Dependent on the Interaction of Prothrombin with the Membrane Surface.

Michael A. Bukys, BS, Tivadar Orban, BS, Paul Y. Kim, BS, Michael E. Nesheim, PhD, Michael Kalafatis, PhD

Blood (2007) 110 (11): 2702.

https://doi.org/10.1182/blood.V110.11.2702.2702

Published: 2007

Journal Articles

Cleavage of Factor Va Heavy Chain at Arg 643 by Thrombin Partially Inactivates the Cofactor.

Evrim Erdogan, BS, Michael A. Bukys, BS, Thomas Orfeo, Ph.D., Kenneth G. Mann, Ph.D., Michael Kalafatis, PhD

Blood (2006) 108 (11): 1703.

https://doi.org/10.1182/blood.V108.11.1703.1703

Published: 2006

Journal Articles

Casein Kinase II Inhibition in MEG-01 Cell Line Results in Apoptosis, Megakaryocytopoiesis and Functional Platelets Release.

Alieta Ciocea, BS, Natalya V. Narizhneva, PhD, Evrim Erdogan, BS, Tatiana V. Byzova, PhD, Michael Kalafatis, PhD

Blood (2005) 106 (11): 4328.

https://doi.org/10.1182/blood.V106.11.4328.4328

Published: 2005

Journal Articles

Human Prothrombin Fragment 1 Conformational Changes Following Binding to Phospholipid Vesicles: A Computational Study.

Tivadar Orban, BS, Michael Kalafatis, PhD

Blood (2005) 106 (11): 4047.

https://doi.org/10.1182/blood.V106.11.4047.4047

Published: 2005

Journal Articles

Evidence That the COOH-Terminal Region of Factor Va Heavy Chain Is Involved in the Regulation of Prothrombinase Activity.

Jamila Hirbawi, BS, Melissa A. Blum, BS, Michael A. Bukys, BS, Tivadar Orban, BS, Michael Kalafatis, PhD

Blood (2005) 106 (11): 1025.

https://doi.org/10.1182/blood.V106.11.1025.1025

Published: 2005

Journal Articles

The Specific Contribution of Amino Acids 334 and 335 from Factor Va Heavy Chain to the Catalytic Efficiency of Prothrombinase.

Melissa A. Blum, BS, Tivadar Orban, BS, Daniel O. Beck, BS, Michael Kalafatis, PhD

Blood (2005) 106 (11): 1027.

https://doi.org/10.1182/blood.V106.11.1027.1027

Published: 2005

Journal Articles

Activated Protein C-Resistance Induced by a Low Molecular Weight Inhibitor.

Michael Kalafatis, PhD, Rihard E. Chiott, PhD, Richard F. Branda, MD, Kenneth G. Mann, PhD

Blood (2005) 106 (11): 2136.

https://doi.org/10.1182/blood.V106.11.2136.2136

Published: 2005

Journal Articles

Exposure of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII.

Michael A. Bukys, BS, Tivadar Orban, BS, Paul Y. Kim, Michael E. Nesheim, PhD, Michael Kalafatis, PhD

Blood (2005) 106 (11): 1951.

https://doi.org/10.1182/blood.V106.11.1951.1951

Published: 2005

Journal Articles

Cofactor Directed Catalysis.

Michael A. Bukys, BS, Paul Kim, BS, Melissa A. Blum, BS, Michael E. Nesheim, PHD, Michael Kalafatis, PHD

Blood (2004) 104 (11): 1715.

https://doi.org/10.1182/blood.V104.11.1715.1715

Published: 2004

NARROW

The Regulatory Function Of Amino Acid Region 473-487 Of Prothrombin During Coagulation

Cleavage At Arg1018 During Thrombin-Mediated Activation of Coagulation Factor V Is Dispensable

The Role of Amino Acids 700–701 of the Factor Va Heavy Chain During Prothrombin Activation by Factor Xa

Amino Acid Region 1000–1008 of Coagulation Factor V Is a Dynamic Regulator for the Emergence of Procoagulant Activity

Role of the N-Terminal Amino Acid Region of Factor Va Light Chain In Prothrombinase Assembly and Function.

The Role of Amino Acids 659-663 of Factor Va Heavy Chain During Prothrombin Activation by Prothrombinase.

Amino Acids Asp695 and Tyr696 of Factor Va Are Essential for Optimal Rate of Prothrombin Activation by Prothrombinase.

Casein Kinase CK2 Inhibition Results in Tumor Suppression.

The Effect of Factor Va on Prothrombinase Function

The Acidic COOH-Terminal Region of Factor Va Heavy Chain Controls the Rate of Prothrombin Activation by Prothrombinase.

Understanding the Factor Va Cofactor Effect within Prothrombinase.

Factor Va Cofactor Activity Is Dependent on the Interaction of Prothrombin with the Membrane Surface.

Cleavage of Factor Va Heavy Chain at Arg 643 by Thrombin Partially Inactivates the Cofactor.

Casein Kinase II Inhibition in MEG-01 Cell Line Results in Apoptosis, Megakaryocytopoiesis and Functional Platelets Release.

Human Prothrombin Fragment 1 Conformational Changes Following Binding to Phospholipid Vesicles: A Computational Study.

Evidence That the COOH-Terminal Region of Factor Va Heavy Chain Is Involved in the Regulation of Prothrombinase Activity.

The Specific Contribution of Amino Acids 334 and 335 from Factor Va Heavy Chain to the Catalytic Efficiency of Prothrombinase.

Activated Protein C-Resistance Induced by a Low Molecular Weight Inhibitor.

Exposure of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII.

Cofactor Directed Catalysis.

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American Society of Hematology

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American Society of Hematology

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