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Michael W.N. Deininger, MD, PhD
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Journal Articles

Long-Term Outcome of Ruxolitinib Treatment in Patients with Myelofibrosis: Durable Reductions in Spleen Volume, Improvements in Quality of Life, and Overall Survival Advantage in COMFORT-I

Srdan Verstovsek, MD, PhD, Ruben A. Mesa, Jason Gotlib, Richard S. Levy, MD, Vikas Gupta, MD, FRCP, FRCPath, John F. DiPersio, MD, PhD, John V. Catalano, MD, Michael W.N. Deininger, MD, PhD, Carole B. Miller, MD, Richard T. Silver, MD, Moshe Talpaz, MD, Elliott F. Winton, MD, Jimmie H. Harvey, Jr., MD, Murat O. Arcasoy, MD, Elizabeth O. Hexner, MD, Roger M. Lyons, MD, Ronald Paquette, MD, PhD, Azra Raza, MD, Kris Vaddi, PhD, Susan Erickson-Viitanen, PhD, William Sun, PhD, Victor A. Sandor, MD, CM, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2012) 120 (21): 800.
https://doi.org/10.1182/blood.V120.21.800.800
Published: 2012
Journal Articles

Chromosomal Abnormalities in the Early Stem Cell Population of CML Patients in Complete Cytogenetic Remission.

Thomas G.P. Bumm, MD, Amy Hanlon Newell, PhD, Jay Oost, Jonathan VanDyke, Susan B. Olson, PhD, Brian J. Druker, MD, Michael W.N. Deininger, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 36.
https://doi.org/10.1182/blood.V110.11.36.36
Published: 2007
Journal Articles

RNAi Functional Screening of the Tyrosine Kinome Identifies Therapeutic Targets in Acute Myeloid Leukemia Patients.

Jeffrey W. Tyner, PhD, Stephanie Willis, BS, Michael W.N. Deininger, MD, PhD, Brian J. Druker, MD
Journal: Blood
Blood (2007) 110 (11): 208.
https://doi.org/10.1182/blood.V110.11.208.208
Published: 2007
Journal Articles

TNF-alpha Plays a Crucial Role in the JAK2-V617F Induced Myeloproliferative Disorder.

Thomas G.P. Bumm, MD, Jonathan VanDyke, Marc Loriaux, MD, PhD, Carolyn Gendron, Lisa G. Wood, PhD, RN, Brian J. Druker, MD, Michael W.N. Deininger, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 675.
https://doi.org/10.1182/blood.V110.11.675.675
Published: 2007
Journal Articles

Inhibition of T315I Bcr-Abl and Other Imatinib-Resistant Bcr-Abl Mutants by the Selective Abl Kinase Inhibitor SGX70393.

Thomas O’Hare, PhD, Christopher A. Eide, Jeffrey W. Tyner, PhD, Matthew J. Wong, Caitlyn A. Smith, Amie S. Corbin, Sean Buchanan, PhD, Katayoun A. Jessen, PhD, Crystal Tang, Kevin Holme, PhD, Stephen K. Burley, MD, PhD, Michael W.N. Deininger, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 1373.
https://doi.org/10.1182/blood.V108.11.1373.1373
Published: 2006
Journal Articles

Monitoring Imatinib Resistance with a “Polony” Assay: Towards Tailored Therapy of Chronic Myelogenous Leukemia (CML).

Valentina Nardi, MD, Tal Raz, PhD, Xinyu Chao, Catherine J. Wu, MD, Richard Stone, MD, Ilene Galinsky, RN, NP, Martha Wadleigh, MD, Michael W.N. Deininger, MD, PhD, George Church, PhD, Jun Zhu, PhD, George Q. Daley, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 837.
https://doi.org/10.1182/blood.V108.11.837.837
Published: 2006
Journal Articles

The F-Box Protein Skp2 Regulates Expression of p27 in BCR-ABL Transformed Cell Lines and Is Required for Induction of Myeloproliferative Disease in a Murine Model.

Anupriya Agarwal, PhD, Thomas G.P. Bumm, MD, Amie Corbin, Thomas O’Hare, PhD, Marc Loriaux, MD, PhD, Stephanie G. Willis, Jutta Deininger, MD, Brian J. Druker, MD, Michael W.N. Deininger, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 742.
https://doi.org/10.1182/blood.V108.11.742.742
Published: 2006
Journal Articles

A Gene Polymorphism within the Kinase Domain of BCR-ABL and Its Effects on Sensitivity to Tyrosine Kinase Inhibitors.

Lucy C. Crossman, MD, Thomas O’Hare, PhD, Thoralf Lange, MD, Stephanie G. Willis, Eric P. Stoffregen, Amie S. Corbin, Stephen G. O’Brien, MD, PhD, Michael C. Heinrich, MD, Brian J. Druker, MD, Peter G. Middleton, PhD, Michael W.N. Deininger, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 1530.
https://doi.org/10.1182/blood.V106.11.1530.1530
Published: 2005
Journal Articles

Comparison of Imatinib, AMN107 and Dasatinib in an Accelerated Cell-Based Mutagenesis Screen.

Michael W.N. Deininger, MD, PhD, Heather Bradeen, MD, Taiping Jia, Thomas O’Hare, PhD, Stephanie G. Willis, Frank Lee, PhD, Brian J. Druker, MD
Journal: Blood
Blood (2005) 106 (11): 691.
https://doi.org/10.1182/blood.V106.11.691.691
Published: 2005
Journal Articles

A Bcr-Abl Mutant Lacking Direct Binding Sites for the Grb2, Cbl and CrkL Adapter Proteins Fails to Induce Leukemia in Mice.

Kara J. Johnson, Ian J. Griswold, PhD, Amie Corbin, Michael W.N. Deininger, MD, PhD, Brian J. Druker, MD
Journal: Blood
Blood (2004) 104 (11): 718.
https://doi.org/10.1182/blood.V104.11.718.718
Published: 2004