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Mikko Myllymaki
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Journal Articles

High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia

Open Access
Petra Nygrén, Jonas Bouhlal, Emmi Jokinen, Sofia Forstén, Essi Laajala, Diogo Dias, Shady Adnan-Awad, Aleksandr Ianevski, Jay Klievink, Hanna Lähteenmäki, Heikki Kuusanmäki, Mikko Myllymäki, Tiina Kasanen, Khalid Saeed, Dean A. Lee, Henrik Hjorth-Hansen, Tero Aittokallio, Olli Dufva, Satu Mustjoki
Journal: Blood
Blood (2025) 145 (15): 1670–1686.
https://doi.org/10.1182/blood.2024025286
Published: 2025
Includes: Supplemental data
Journal Articles

Somatic symphony: telomeres and CH

Free
Mikko Myllymäki, Christopher R. Reilly
Journal: Blood
Blood (2024) 144 (23): 2369–2371.
https://doi.org/10.1182/blood.2024026841
Published: 2024
Journal Articles

Comprehensive Drug Profiling and CRISPR Screening Reveal Essential Pathways for NK Cell Cytotoxicity

Free
Jonas Bouhlal, Emmi Jokinen, Petra Nygren, Diogo Dias, Aleksandr Ianevski, Jay Klievink, Hanna Lähteenmäki, Essi Laajala, Hanna Duàn, Emmi Järvelä, Helka Göös, Matti Korhonen, Salomé Decombis, Konstantin Matjusinski, Mikko Myllymäki, Maija Hollmén, Khalid Saeed, Dean Anthony Lee, Tero Aittokallio, Sara Gandolfi, Olli Dufva, Satu Mustjoki
Journal: Blood
Blood (2024) 144 (Supplement 1): 913.
https://doi.org/10.1182/blood-2024-202448
Published: 2024
Journal Articles

Clonal Hematopoiesis Mutations and Cell-Free DNA Characteristics in Patients with High-Risk Large B-Cell Lymphomas

Free
Miro Nylén, Leo Meriranta, Emil Hiitola, Maare Arffman, Harald Holte, Judit Mészáros Joergensen, Peter Brown, Sirkku Jyrkkiö, Mats Jerkeman, Øystein Fluge, Magnus Björkholm, Lars Møller Pedersen, Mikael Eriksson, Satu Mustjoki, Sirpa Leppä, Mikko Myllymäki
Journal: Blood
Blood (2024) 144 (Supplement 1): 1601.
https://doi.org/10.1182/blood-2024-201928
Published: 2024
Journal Articles

Bone Marrow Stromal Cells Hamper Leukemia Cell Induced NK Cell Activation and Cytotoxicity

Free
Salomé Decombis, Johannes Smolander, Jonas Bouhlal, Jay Klievink, Hanna Lähteenmäki, Emmi Jokinen, Linh Lin, Hanna Laitinen, Konstantin Matjusinski, Eveliina Holappa, Mikko Myllymäki, Heidi Haikala, Sara Gandolfi, Satu Mustjoki
Journal: Blood
Blood (2024) 144 (Supplement 1): 4814.
https://doi.org/10.1182/blood-2024-202959
Published: 2024
Journal Articles

Clonal Hematopoiesis Associated with Rheumatoid Arthritis

Free
Emil Hiitola, Juuso Korhonen, Jukka Koskela, Matti Kankainen, Milla Alakuijala, Heidi Kokkonen, Aoxing Liu, Paavo Häppölä, Paula Savola, Tiina Kelkka, Marjatta Leirisalo-Repo, Ritva Peltomaa, Laura Pirilä, Pia Isomäki, Markku Kauppi, Oili Kaipiainen-Seppänen, FinnGen Consortium, Giulio Genovese, Andrea Ganna, Solbritt Rantapää-Dahlqvist, Satu Mustjoki, Mikko Myllymäki
Journal: Blood
Blood (2023) 142 (Supplement 1): 2698.
https://doi.org/10.1182/blood-2023-173664
Published: 2023
Journal Articles

Single-Cell Transcriptomics Reveals Adaptive NK Cell and Antigen-Specific T Cell Responses Shaped by CMV Viremia Post-Hematopoietic Stem Cell Transplant

Free
Aino-Elina Häkkinen, Jani Huuhtanen, Sofie Lundgren, Riitta Niittyvuopio, Harri Lähdesmäki, Mikko A. I. Keränen, Mikko Myllymäki, Satu Mustjoki
Journal: Blood
Blood (2023) 142 (Supplement 1): 4786.
https://doi.org/10.1182/blood-2023-179714
Published: 2023
Journal Articles

Clonal Hematopoiesis in Cartilage-Hair Hypoplasia

Free
Miro Nylén, Svetlana Vakkilainen, Emil Hiitola, Jukka Koskela, Mervi Taskinen, Satu Mustjoki, Outi Mäkitie, Mikko Myllymäki
Journal: Blood
Blood (2023) 142 (Supplement 1): 5667.
https://doi.org/10.1182/blood-2023-174194
Published: 2023
Journal Articles

Somatic Mutations in T Cells in Patients with Hematological Diseases

Free
Sofie Lundgren, Timo Järvinen, Mikko A Keränen, Jason Theodoropoulos, Daehong Kim, Urpu Salmenniemi, Gunilla Walldin, Paula Savola, Tiina Kelkka, Hanna Rajala, Pekka Ellonen, Eva Hellström-Lindberg, Maija Itälä-Remes, Mikko Myllymäki, Matti Kankainen, Satu Mustjoki
Journal: Blood
Blood (2022) 140 (Supplement 1): 5496–5497.
https://doi.org/10.1182/blood-2022-163112
Published: 2022
Journal Articles

A Comprehensive, Multiomics Analysis of Natural Killer-Cell Malignancies

Free
Petra Johanna Nygren, Aino Häkkinen, Daehong Kim, Timo Jarvinen, Fumihiro Ishida, Stefania Bortoluzzi, Andrea Binatti, Vanessa Rebecca Gasparini, Renato Zambello, Mikko Myllymäki, Seishi Ogawa, Yusuke Okuno, Hiroshi Kimura, John Chan, Olli Dufva, Satu Mustjoki, Matti Kankainen
Journal: Blood
Blood (2022) 140 (Supplement 1): 6390–6391.
https://doi.org/10.1182/blood-2022-162285
Published: 2022
Journal Articles

Somatic STAT3 Mutations in CD8+ T Cells of HTLV-2 Positive Blood Donors

Free
Daehong Kim, Mikko Myllymäki, Matti Kankainen, Timo Jarvinen, Giljun Park, Roberta Bruhn, Edward L Murphy, Satu Mustjoki
Journal: Blood
Blood (2021) 138 (Supplement 1): 3133.
https://doi.org/10.1182/blood-2021-146326
Published: 2021
Journal Articles

The clinical and functional effects of TERT variants in myelodysplastic syndrome

Free
Christopher R. Reilly, Mikko Myllymäki, Robert Redd, Shilpa Padmanaban, Druha Karunakaran, Valerie Tesmer, Frederick D. Tsai, Christopher J. Gibson, Huma Q. Rana, Liang Zhong, Wael Saber, Stephen R. Spellman, Zhen-Huan Hu, Esther H. Orr, Maxine M. Chen, Immaculata De Vivo, Daniel J. DeAngelo, Corey Cutler, Joseph H. Antin, Donna Neuberg, Judy E. Garber, Jayakrishnan Nandakumar, Suneet Agarwal, R. Coleman Lindsley
Journal: Blood
Blood (2021) 138 (10): 898–911.
https://doi.org/10.1182/blood.2021011075
Published: 2021
Includes: Supplemental data
Journal Articles

Short telomere length predicts nonrelapse mortality after stem cell transplantation for myelodysplastic syndrome

Free
Clinical Trials & Observations
Mikko Myllymäki, Robert Redd, Christopher R. Reilly, Wael Saber, Stephen R. Spellman, Christopher J. Gibson, Zhen-Huan Hu, Tao Wang, Esther H. Orr, Jaclyn G. Grenier, Maxine M. Chen, David P. Steensma, Corey Cutler, Immaculata De Vivo, Joseph H. Antin, Donna Neuberg, Suneet Agarwal, R. Coleman Lindsley
Journal: Blood
Blood (2020) 136 (26): 3070–3081.
https://doi.org/10.1182/blood.2020005397
Published: 2020
Includes: Supplemental data
Journal Articles

Telomere Length and Telomerase Complex Mutations Predict Fatal Treatment Toxicity after Stem Cell Transplantation in Patients with Myelodysplastic Syndrome

Free
Mikko Myllymaki, MD PhD, Robert A. Redd, MS, Corey S. Cutler, MD MPH, Wael Saber, MD MS, Zhen-Huan Hu, MPH, Tao Wang, PhD, Stephen R. Spellman, Christopher J. Gibson, MD, Maxine M Chen, Esther Orr, David P. Steensma, MD, Joseph H. Antin, MD, Immaculata De Vivo, Donna S Neuberg, ScD, Suneet Agarwal, MDPhD, R. Coleman Lindsley, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 796.
https://doi.org/10.1182/blood-2018-99-117031
Published: 2018
Journal Articles

Extramedullary Erythropoiesis in Spleen of HIF Prolyl 4-Hydroxylase-2 Deficient Mice Is Mediated By Notch Signaling Downregulation

Free
Mikko Myllymäki, MD PhD, Jenni Määttä, MD Cand., Elitsa Dimova, PhD, Valerio Izzi, PhD, Timo Väisänen, PhD, Johanna Myllyharju, Professor, Peppi Koivunen, Professor, Raisa Serpi, PhD
Journal: Blood
Blood (2016) 128 (22): 2656.
https://doi.org/10.1182/blood.V128.22.2656.2656
Published: 2016