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Mira Patel, PhD
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Journal Articles

GBT1118 Diminishes Vaso-Occlusion in Sickle Cell Disease Mice

Carsten Alt, PhD, Perry Liu, Chien-Ming Li, PhD, Abel Silva, Peter Rademacher, PhD, Hilary Zou, Mira Patel, PhD, Kobina Dufu, PhD, Donna Oksenberg, PhD, Katalin Kauser, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3516.
https://doi.org/10.1182/blood.V130.Suppl_1.3516.3516
Published: 2017
Journal Articles

Long-Term Dosing in Sickle Cell Disease Subjects with GBT440, a Novel HbS Polymerization Inhibitor

Josh Lehrer-Graiwer, MDMPhil, FACC, Jo Howard, MB, BChir, Claire Jane Hemmaway, MD, Moji Awogbade, Paul Telfer, FRCPath,MD, Mark Layton, MB, FRCP, John B. Porter, MD, Timothy Mant, MB, FFPM, FRCP, Kobina Dufu, PhD, Athiwat Hutchaleelaha, PhD, Donna Oksenberg, PhD, Mira Patel, PhD, Margaret Eleanor Tonda, PharmD, Kenneth Bridges, MD, Eleanor Ramos, MD
Journal: Blood
Blood (2016) 128 (22): 2488.
https://doi.org/10.1182/blood.V128.22.2488.2488
Published: 2016
Journal Articles

GBT440 Demonstrates High Specificity for Red Blood Cells in Nonclinical Species

Athiwat Hutchaleelaha, PhD, Mira Patel, PhD, Abel Silva, Donna Oksenberg, PhD, Brian Metcalf, PhD
Journal: Blood
Blood (2015) 126 (23): 2172.
https://doi.org/10.1182/blood.V126.23.2172.2172
Published: 2015
Journal Articles

GBT440, a Potent Anti-Sickling Hemoglobin Modifier Reduces Hemolysis, Improves Anemia and Nearly Eliminates Sickle Cells in Peripheral Blood of Patients with Sickle Cell Disease

Josh Lehrer-Graiwer, MDMPhil, FACC, Jo Howard, MD, Claire Jane Hemmaway, MD, Moji Awogbade, Paul Telfer, FRCPath,MD, Mark Layton, MB, FRCP, Timothy Mant, MB, FFPM, FRCP, Kobina Dufu, PhD, Athiwat Hutchaleelaha, PhD, Teri Koller, MBA, Donna Oksenberg, PhD, Mira Patel, PhD, Eleanor Ramos, MD
Journal: Blood
Blood (2015) 126 (23): 542.
https://doi.org/10.1182/blood.V126.23.542.542
Published: 2015
Journal Articles

GTx011, an Anti-Sickling Compound, Improves SS Blood Rheology By Reduction of HbS polymerization Via Allosteric Modulation of O 2 Affinity

Mira Patel, PhD, Pedro Cabrales, PhD, Kobina Dufu, PhD, Brian Metcalf, PhD, Uma Sinha, PhD
Journal: Blood
Blood (2014) 124 (21): 1370.
https://doi.org/10.1182/blood.V124.21.1370.1370
Published: 2014
Journal Articles

GTx011, a Novel Agent That Improves Rheological Properties Of Sickle Cell Blood By Increasing Oxygen Affinity For Hemoglobin

Mira Patel, PhD, Donna Oksenberg, PhD, Abel Silva, BS, Andreas Betz, PhD, Brian Metcalf, PhD, Uma Sinha, PhD
Journal: Blood
Blood (2013) 122 (21): 2207.
https://doi.org/10.1182/blood.V122.21.2207.2207
Published: 2013