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Mirella Ezban, PhD
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Journal Articles

In Hemophilia Α Plasma Treated with Emicizumab, Factor IXa in Activated Prothrombin Complex Concentrates Is the Dominant Contributor to Enhanced Thrombin Generation

Dougald Monroe, PhD, Mirella Ezban, PhD, Maureane Hoffman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-139586
Published: 2020
Journal Articles

In Hemophilia Α Plasma Treated with Emicizumab, Factor IX Activation By Factor VIIa Drives Thrombin Generation

Dougald Monroe, PhD, Mirella Ezban, PhD, Maureane Hoffman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-139712
Published: 2020
Journal Articles

Evaluation of a Next-Generation FVIII Mimetic Antibody, Mim8, in Combination with Recombinant FVIIa, FVIII and Activated Prothrombin Complex Concentrate

Laurent Burnier, PhD, Mette B Hermit, PhD, Ida Hilden, Mirella Ezban, PhD, Stine L Kjellev, PhDDVM
Journal: Blood
Blood (2019) 134 (Supplement_1): 2388.
https://doi.org/10.1182/blood-2019-123340
Published: 2019
Journal Articles

Recombinant FVIII and FVIIa Added to Flowing Hemophiliac Blood Co-Localize with Platelet Aggregates Adherent to a Collagen Surface, Promoting Local Fibrin Deposition in Wake-like Patterns Around the Aggregates

Eric F. Grabowski, MD ScD, Bohan Liu, BA, Matthew Gerace, BA, Paul E. Grabowski, PhD, Peter Gunnarsson, PhD, Mirella Ezban, PhD
Journal: Blood
Blood (2015) 126 (23): 3499.
https://doi.org/10.1182/blood.V126.23.3499.3499
Published: 2015
Journal Articles

The Effect of Prophylactic Recombinant Factor IX and Glycopegylated Factor IX to Normalize Articular Wound Healing Following Hemarthrosis Examined in Hemophilia B Mice

Junjiang Sun, MD, Eric Livingston, Tom Knudsen, DVM, PhD, Dougald M. Monroe, III, PhD, Mirella Ezban, PhD, Ted Bateman, PhD, Paul E. Monahan, MD
Journal: Blood
Blood (2015) 126 (23): 549.
https://doi.org/10.1182/blood.V126.23.549.549
Published: 2015
Journal Articles

Pharmacokinetics of Multiple Doses of rFVIIa in Patients with Hemophilia With and Without Inhibitors

Camilla Stenmo, MSc, Ihosvany Fernandez-Bello, BSPharm, Mirella Ezban, PhD, Nora V. Butta, Víctor Jiménez-Yuste, PhD
Journal: Blood
Blood (2014) 124 (21): 2824.
https://doi.org/10.1182/blood.V124.21.2824.2824
Published: 2014
Journal Articles

Formation of FVIIa-Antithrombin Complexes After Administration of rFVIIa to Hemophilia Patients.

Mirella Ezban, PhD, Erika Martin, MT, (ASCP), John Christian Barrett, MD, Janice Kuhn, RN, Mindy Nolte, Hermann Pelzer, Henrik Agerso, Lars Christian Petersen, Ulla Hedner, MD, PhD, Marcus E. Carr, Jr., MD, PhD, Donald Brophy, Pharm.D.
Journal: Blood
Blood (2009) 114 (22): 1295.
https://doi.org/10.1182/blood.V114.22.1295.1295
Published: 2009
Journal Articles

Evaluation of Clotting Parameters in a Patient with Hemophilia A and Inhibitors Who Has a Poor Clinical Response to Standard Dose rFVIIa.

Marcus E. Carr, Jr., MD, PhD, Erika J Martin, MT(ASCP), John Christian Barrett, MD, Mindy Nolte, RN, Janice Kuhn, RN, Mirella Ezban, PhD, Ulla Hedner, MD, PhD, Donald Brophy
Journal: Blood
Blood (2009) 114 (22): 4440.
https://doi.org/10.1182/blood.V114.22.4440.4440
Published: 2009
Journal Articles

Differences in Global Hemostasis Following rFVIIa Dosing: A Focus On Responders Versus Poor Responders.

Donald Brophy, Erika Martin, MT, (ASCP), John Christian Barrett, MD, Mindy Nolte, RN, Janice Kuhn, RN, Marcus E. Carr, Jr., MD, PhD, Mirella Ezban, PhD, Ulla Hedner, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3485.
https://doi.org/10.1182/blood.V114.22.3485.3485
Published: 2009
Journal Articles

Acidosis in Human Whole Blood Does Not Necessarily Impair the Coagulation and the Effect of RFVIIa.

Dorthe Viuff, PhD, Marianne Kjalke, PhD, Vivian Lind, Egon Persson, PhD, Mirella Ezban, PhD
Journal: Blood
Blood (2007) 110 (11): 3930.
https://doi.org/10.1182/blood.V110.11.3930.3930
Published: 2007
Journal Articles

In Vitro Evaluation of the Effect of rFVIIa on Anti Coagulated Human Whole Blood Treated with Abciximab Using Thromboelastography (TEG).

Dorthe Viuff, PhD, Soeren Andersen, PhD, Brian Lauritzen, PhD, Mirella Ezban, PhD
Journal: Blood
Blood (2006) 108 (11): 1114.
https://doi.org/10.1182/blood.V108.11.1114.1114
Published: 2006
Journal Articles

Single-Dose Pharmacokinetics of Murine and Human Recombinant Activated FVII in Mice.

Anne Steinoe, MSc, Ditte M. Karpf, PhD, Henning R. Stennicke, PhD, Mirella Ezban, PhD, Brit B. Sorensen, PhD
Journal: Blood
Blood (2006) 108 (11): 4023.
https://doi.org/10.1182/blood.V108.11.4023.4023
Published: 2006
Journal Articles

A Variant of Recombinant Factor VIIa with Enhanced Procoagulant and Antifibrinolytic Activities in a Model of Hemophilia.

Alisa S. Wolberg, PhD, Egon Persson, PhD, Ulla Hedner, MD, Mirella Ezban, PhD, Geoffrey A. Allen, MD
Journal: Blood
Blood (2006) 108 (11): 767.
https://doi.org/10.1182/blood.V108.11.767.767
Published: 2006
Journal Articles

Enhanced Fibrin Clot Formation and Stability with a Superactive Analog of Factor VIIa in an In Vitro Model of Hemophilia.

Alisa S. Wolberg, PhD, Mirella Ezban, PhD, Ulla Hedner, MD, Egon Persson, PhD
Journal: Blood
Blood (2005) 106 (11): 4056.
https://doi.org/10.1182/blood.V106.11.4056.4056
Published: 2005