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Journal Articles

Somatic Loss of HLA Class I Alleles Is a Common Genetic Alteration in Acquired Aplastic Anemia and Reveals Aplastic Anemia Risk Alleles

Daria V. Babushok, MD PhD, Jamie Duke, Hongbo M. Xie, Deborah Ferriola, Natasha Stanley, Jamie Atienza, Hugh Huang, Jaclyn A Biegel, Monica Bessler, MD PhD, Dimitri S. Monos, PhD, Timothy S. Olson, MD PhD

Blood (2016) 128 (22): 730.

https://doi.org/10.1182/blood.V128.22.730.730

Published: 2016

Journal Articles

Expression of HMGA2 Collaborates with JAK2V617F to Progress Myeloproliferative Neoplasms

Koki Ueda, MD PhD, Kazuhiko Ikeda, MD PhD, Kazuei Ogawa, MD PhD, Akiko Shichishima-Nakamura, MD PhD, Kotaro Shide, MD PhD, Kazuya Shimoda, MD PhD, Yuko Hashimoto, MD PhD, Philip J Mason, PhD, Monica Bessler, MD PhD, Yasuchika Takeishi, MD PhD

Blood (2015) 126 (23): 482.

https://doi.org/10.1182/blood.V126.23.482.482

Published: 2015

Journal Articles

Disrupted Lymphocyte Homeostasis in Hepatitis-Associated Acquired Aplastic Anemia Is Associated with Very Low Telomere Lengths

Anne-Laure Grignon, MD BA, MA, Daria V. Babushok, MD PhD, Li Yimei, PhD, Helge Hartung, MD, Ho-Sun Lam, Monica Bessler, MD PhD, Timothy S. Olson, MDPhD

Blood (2015) 126 (23): 2408.

https://doi.org/10.1182/blood.V126.23.2408.2408

Published: 2015

Journal Articles

Expression of Let-7 Micro RNAs in Transgenic Mice Overexpressing Truncated Hmga2

Kazuhiko Ikeda, MD, PhD, Kayo Harada, MD, Kazuei Ogawa, MD, PhD, Philip J Mason, PhD, Monica Bessler, MD, PhD, Yasuchika Takeishi, MD, PhD

Blood (2012) 120 (21): 3470.

https://doi.org/10.1182/blood.V120.21.3470.3470

Published: 2012

Journal Articles

Eculizumab Protects Against TE and Prolongs Survival in Patients with Paroxysmal Nocturnal Hemoglobinuria: An International PNH Registry Study

Gérard Socié, MD PhD, Hubert Schrezenmeier, MD, Petra Muus, MD, PhD, Jeffrey Szer, MBBS, Alvaro Urbano-Ispizua, MD, Jaroslaw P. Maciejewski, MD, PhD, Robert A. Brodsky, MD, Monica Bessler, MD, PhD, Yuzuru Kanakura, MD, PhD, Wendell F. Rosse, MD, Gus Khursigara, PhD, Camille L. Bedrosian, MD, Peter Hillmen, MBChB, PhD

Blood (2012) 120 (21): 3480.

https://doi.org/10.1182/blood.V120.21.3480.3480

Published: 2012

Journal Articles

Clinical Characteristics of Classic Paroxysmal Nocturnal Hemoglobinuria (PNH) in Pediatric Patients: A Comparison with Classic PNH in Adults. An International PNH Registry Study

Alvaro Urbano-Ispizua, MD, Hubert Schrezenmeier, MD, Petra Muus, MD, PhD, Jaroslaw P Maciejewski, MD, PhD, Gérard Socié, Jeffrey Szer, MBBS, FRACP, Robert A. Brodsky, MD, Monica Bessler, MD, PhD, Wendell F Rosse, MD, Yuzuru Kanakura, Gus Khursigara, PhD, Camille L Bedrosian, MD, Peter Hillmen, MBChB, PhD

Blood (2011) 118 (21): 2102.

https://doi.org/10.1182/blood.V118.21.2102.2102

Published: 2011

Journal Articles

Common Recurrent DKC1 Mutation A353V Does Not Support Telomere Maintenance in Induced Pluripotent Stem Cells

Baiwei Gu, Ph.D, Jason A. Mills, PhD, Jian-meng Fan, B.S, Deborah L. French, PhD, Monica Bessler, MD, PhD, Philip Mason, PhD

Blood (2011) 118 (21): 50.

https://doi.org/10.1182/blood.V118.21.50.50

Published: 2011

Journal Articles

Use of Blood Transfusions In Paroxysmal Nocturnal Hemoglobinuria Patients with and without Aplastic Anemia Enrolled In the Global PNH Registry

Hubert Schrezenmeier, Robert A Brodsky, MD, Petra Muus, MD, PhD, Monica Bessler, MD, PhD, Jeffrey Szer, MBBS, FRACP, Jaroslaw P Maciejewski, MD, PhD, FACP, Gérard Socié, Alvaro Urbano-Ispizua, MD, Yuzuru Kanakura, MD, PhD, Britta Hoechsmann, Wendell F Rosse, MD, Gus Khursigara, PhD, Anders Karnell, MD, PhD, Camille L Bedrosian, MD, Peter Hillmen, MBChB, FRCP, FRCPath, PhD

Blood (2010) 116 (21): 2241.

https://doi.org/10.1182/blood.V116.21.2241.2241

Published: 2010

Journal Articles

Evaluation of Paroxysmal Nocturnal Hemoglobinuria Disease Burden: The Patient's Perspective. A Report From the International PNH Registry.

Petra Muus, MD, PhD, Jeffrey Szer, MBBS, FRACP, Hubert Schrezenmeier, MD, Professor, Robert A Brodsky, MD, Monica Bessler, MD, PhD, Gérard Socié, Alvaro Urbano-Ispizua, MD, Jaroslaw P Maciejewski, MD, PhD, FACP, Wendell F Rosse, MD, Yuzuru Kanakura, MD, PhD, Gus Khursigara, PhD, Anders Karnell, MD, PhD, Camille L Bedrosian, MD, Peter Hillmen, MBChB, FRCP, FRCPath, PhD

Blood (2010) 116 (21): 1525.

https://doi.org/10.1182/blood.V116.21.1525.1525

Published: 2010

Journal Articles

Features of Myeloproliferative Neoplasms and Clonal Advantage of Hematopoietic Stem Cells In Mice Expressing An Hmga2 cDNA Lacking the 3′UTR.

Kazuhiko Ikeda, MD, PhD, Philip J Mason, PhD, Monica Bessler, MD, PhD

Blood (2010) 116 (21): 1161.

https://doi.org/10.1182/blood.V116.21.1161.1161

Published: 2010

Journal Articles

The Effects of Pathogenic Dkc1 Mutations on Telomerase and Ribosome Biogenesis.

Baiwei Gu, Ph.D, Jian-meng Fan, B.S, Rachel Idol, Ph.D, Monica Bessler, MD, PhD, Philip J Mason, Ph.D

Blood (2010) 116 (21): 1163.

https://doi.org/10.1182/blood.V116.21.1163.1163

Published: 2010

Journal Articles

Antioxidant Treatment Rescues An Accelerated Aging Phenotype In Dyskerin Mutated Bone Marrow Stem Cells.

Baiwei Gu, Ph.D, Jian-meng Fan, B.S, Monica Bessler, MD, PhD, Philip J Mason, Ph.D

Blood (2010) 116 (21): 2614.

https://doi.org/10.1182/blood.V116.21.2614.2614

Published: 2010

Journal Articles

Global Differences in RBC Membrane Protein Expression Between Normal and PNH Individuals.

Jeffrey Hiken, PhD, Richard LeDuc, PhD, Petra Gilmore, Henry Rohrs, PhD, R. Reid Townsend, MD, PhD, Monica Bessler, MD, PhD

Blood (2009) 114 (22): 1986.

https://doi.org/10.1182/blood.V114.22.1986.1986

Published: 2009

Journal Articles

DNA Damage Accumulation, Accelerated Hematopoietic Stem Cell Aging, and Partial Reversal by Antioxidant Treatment in a Mouse Model of Dyskeratosis Congenita.

Baiwei Gu, PhD, JianMeng Fan, Monica Bessler, MD, PhD, Philip Mason, PhD

Blood (2009) 114 (22): 498.

https://doi.org/10.1182/blood.V114.22.498.498

Published: 2009

Journal Articles

Terminal Complement Inhibitor Eculizumab Improves Complement-Mediated Platelet Consumption and Thrombocytopenia in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH).

Gerard Socie, MD, PhD, Petra Muus, MD, PhD, Hubert Schrezenmeier, MD, Britta Höchsmann, MD, Jaroslaw P. Maciejewski, MD, PhD, Ilene Ceil Weitz, MD, Anita Hill, PhD, MBChB, (Hons), Monica Bessler, MD, PhD, Antonio M. Risitano, MD, PhD

Blood (2009) 114 (22): 4030.

https://doi.org/10.1182/blood.V114.22.4030.4030

Published: 2009

Journal Articles

A Global Registry of Patients with Paroxysmal Nocturnal Hemoglobinuria.

Robert Brodsky, Hubert Schrezenmeier, MD, Petra Muus, MD, PhD, Monica Bessler, MD, PhD, Jeffrey Szer, MBBS, FRACP, Bruno Rotoli, MD, Jaroslaw P. Maciejewski, MD, PhD, Gerard Socie, MD, PhD, A. Urbano-Ispizua, MD, Wendell F. Rosse, MD, Yuzuru Kanakura, MD, PhD, Anders Karnell, Camille Bedrosian, MD, Peter Hillmen, MB, ChB, PhD

Blood (2009) 114 (22): 3007.

https://doi.org/10.1182/blood.V114.22.3007.3007

Published: 2009

Journal Articles

Eculizumab Reduces Pulmonary Hypertension through Inhibition of Hemolysis-Associated Nitric Oxide Consumption in Patients with Paroxysmal Nocturnal Hemoglobinuria

Anita Hill, MD, Russell P. Rother, PhD, Xunde Wang, MD, Robert J Sapsford, MD, Paul O Collinson, MD, David C Gaze, PhD, Sidney M Morris, Jr., PhD, Andrew Scally, Kerry Quinn-Senger, PhD, Stephen J Richards, PhD, Monica Bessler, MD, PhD, Richard Kelly, MD, Peter Hillmen, MBChB, PhD, Mark Gladwin, MD

Blood (2008) 112 (11): 486.

https://doi.org/10.1182/blood.V112.11.486.486

Published: 2008

Journal Articles

Homozygous and Compound Heterozygous Mutations in the Telomerase Reverse Transcriptase Gene in Two Families with Spontaneous Dyskeratosis Congenita and Idiopathic Aplastic Anemia.

Hong-Yan Du, MD, PhD, Elena Pumbo, BSC, Peter Manley, MD, David B. Wilson, MD, Philip Mason, PHD, Monica Bessler, MD, PHD

Blood (2007) 110 (11): 1675.

https://doi.org/10.1182/blood.V110.11.1675.1675

Published: 2007

Journal Articles

Significance of Telomere Length Measurement in the Diagnosis of Dyskeratosis Congenita.

Hong-Yan Du, MD, PhD, Elena Pumbo, Akiko Shimamura, MD, Adrianna Vlachos, MD, Jeffrey M. Lipton, MD, Fred Goldman, MD, David B. Wilson, MD, Philip Mason, PHD, Monica Bessler, MD, PHD

Blood (2007) 110 (11): 836.

https://doi.org/10.1182/blood.V110.11.836.836

Published: 2007

Journal Articles

Significant Disease Burden in Paroxysmal Nocturnal Hemoglobinuria Patients with Lower Levels of Hemolysis, Mild Anemia and Minimal Transfusion: Clinical Improvement with Eculizumab Therapy.

Monica Bessler, MD, PhD, Hubert Schrezenmeier, MD, Jaroslaw P. Maciejewski, MD PhD, Anita Hill, MB ChB, Scott A. Rollins, PhD, Neal S. Young, MD, Lucio Luzzatto, MD

Blood (2007) 110 (11): 840.

https://doi.org/10.1182/blood.V110.11.840.840

Published: 2007

NARROW

Somatic Loss of HLA Class I Alleles Is a Common Genetic Alteration in Acquired Aplastic Anemia and Reveals Aplastic Anemia Risk Alleles

Expression of HMGA2 Collaborates with JAK2V617F to Progress Myeloproliferative Neoplasms

Disrupted Lymphocyte Homeostasis in Hepatitis-Associated Acquired Aplastic Anemia Is Associated with Very Low Telomere Lengths

Expression of Let-7 Micro RNAs in Transgenic Mice Overexpressing Truncated Hmga2

Eculizumab Protects Against TE and Prolongs Survival in Patients with Paroxysmal Nocturnal Hemoglobinuria: An International PNH Registry Study

Clinical Characteristics of Classic Paroxysmal Nocturnal Hemoglobinuria (PNH) in Pediatric Patients: A Comparison with Classic PNH in Adults. An International PNH Registry Study

Common Recurrent DKC1 Mutation A353V Does Not Support Telomere Maintenance in Induced Pluripotent Stem Cells

Use of Blood Transfusions In Paroxysmal Nocturnal Hemoglobinuria Patients with and without Aplastic Anemia Enrolled In the Global PNH Registry

Evaluation of Paroxysmal Nocturnal Hemoglobinuria Disease Burden: The Patient's Perspective. A Report From the International PNH Registry.

Features of Myeloproliferative Neoplasms and Clonal Advantage of Hematopoietic Stem Cells In Mice Expressing An Hmga2 cDNA Lacking the 3′UTR.

The Effects of Pathogenic Dkc1 Mutations on Telomerase and Ribosome Biogenesis.

Antioxidant Treatment Rescues An Accelerated Aging Phenotype In Dyskerin Mutated Bone Marrow Stem Cells.

Global Differences in RBC Membrane Protein Expression Between Normal and PNH Individuals.

DNA Damage Accumulation, Accelerated Hematopoietic Stem Cell Aging, and Partial Reversal by Antioxidant Treatment in a Mouse Model of Dyskeratosis Congenita.

Terminal Complement Inhibitor Eculizumab Improves Complement-Mediated Platelet Consumption and Thrombocytopenia in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH).

A Global Registry of Patients with Paroxysmal Nocturnal Hemoglobinuria.

Eculizumab Reduces Pulmonary Hypertension through Inhibition of Hemolysis-Associated Nitric Oxide Consumption in Patients with Paroxysmal Nocturnal Hemoglobinuria

Homozygous and Compound Heterozygous Mutations in the Telomerase Reverse Transcriptase Gene in Two Families with Spontaneous Dyskeratosis Congenita and Idiopathic Aplastic Anemia.

Significance of Telomere Length Measurement in the Diagnosis of Dyskeratosis Congenita.

Significant Disease Burden in Paroxysmal Nocturnal Hemoglobinuria Patients with Lower Levels of Hemolysis, Mild Anemia and Minimal Transfusion: Clinical Improvement with Eculizumab Therapy.

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American Society of Hematology

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American Society of Hematology

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