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Journal Articles

The Cytotoxic Effect of the PARP Inhibitor ABT-888 on Myeloproliferative Neoplasms

Pritesh R. Patel, MB, ChB, Vitalyi Senyuk, PhD, Elisa Bonetti, PhD, Dolores Mahmud, PhD, Shrihari S. Kadkol, MD PhD, Annie L. Oh, MD, Nadim Mahmud, MD PhD, Damiano Rondelli, MD

Blood (2016) 128 (22): 4276.

https://doi.org/10.1182/blood.V128.22.4276.4276

Published: 2016

Journal Articles

In-Vitro and in-Vivo Synergistic Effect of Melphalan and Dual DNA Repair Inhibition in Multiple Myeloma

Pritesh R. Patel, MB, ChB, Annie L. Oh, MD, Vitalyi Senyuk, PhD, Dolores Mahmud, PhD, Nadim Mahmud, MD PhD, Damiano Rondelli, MD

Blood (2016) 128 (22): 3301.

https://doi.org/10.1182/blood.V128.22.3301.3301

Published: 2016

Journal Articles

Targeted Depletion of Amino Acids As a Novel Therapy for Acute Leukemia and Other Cancers: Mechanisms and Countermechanisms

Aysenur Esen, MD, Anwar A Khan, PhD, Jason Chan, Nadim Mahmud, MD PhD, John G. Quigley, MD

Blood (2016) 128 (22): 4716.

https://doi.org/10.1182/blood.V128.22.4716.4716

Published: 2016

Journal Articles

A Phase 1 Study of Total Marrow Irradiation Combined with High-Dose Melphalan for Patients with Relapsed/ Refractory Multiple Myeloma

Pritesh R. Patel, MB, ChB, Annie L. Oh, MD, Matthew Koshy, MD, Bulent Aydogan, PhD, Karen Sweiss, PharmD, John G. Quigley, MD, Santosh L. Saraf, MD, Irum Khan, MD, Eileen D. Hacker, PhD APN, AOCN, Nadim Mahmud, MD PhD, David J. Peace, MD, Howard Ozer, MD PhD, Jennifer Windhorst, APN, Ralph R Weichselbaum, MD, Damiano Rondelli, MD

Blood (2016) 128 (22): 4646.

https://doi.org/10.1182/blood.V128.22.4646.4646

Published: 2016

Journal Articles

A Preclinical Non-Human Primate Model to Test Reversible Myeloablation Following IV Busulfan Therapy without Stem Cell Rescue

Nadim Mahmud, MD PhD, Amit Khanal, MD, Simona Taioli, MS, Emre Koca, MD, Sujata Gaitonde, MD FACP, Benjamin Petro, BS, Karen Sweiss, PharmD, Damiano Rondelli, MD

Blood (2015) 126 (23): 1868.

https://doi.org/10.1182/blood.V126.23.1868.1868

Published: 2015

Journal Articles

Preclinical Study for the Use of Abatacept to Prevent Rejection of Allogeneic CD34+ Cells in a Xenograft Model

Annie L. Oh, MD, Dolores Mahmud, PhD, Vitalyi Senyuk, PhD, Elisa Bonetti, PhD, Nadim Mahmud, MD PhD, Pritesh R. Patel, MB, ChB, Damiano Rondelli, MD

Blood (2015) 126 (23): 4271.

https://doi.org/10.1182/blood.V126.23.4271.4271

Published: 2015

Journal Articles

Alemtuzumab/Low Dose Radiation Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation for Adult Patients with Sickle Cell Disease (SCD)

Santosh L. Saraf, MD, Annie L. Oh, MD, Dolores Mahmud, PhD, Pritesh R. Patel, MB, ChB, Karen Sweiss, PharmD, Matthew Koshy, MD, Sally Campbell-Lee, MD, Michel Gowhari, DO, Johara Hassan, MD, David Peace, MD, John G. Quigley, MD, Irum Khan, MBBS, Robert E. Molokie, MD, Lewis L. Hsu, MD PhD, Nadim Mahmud, MD PhD, Dennis J Levinson, MD, Victor R. Gordeuk, MD, Damiano Rondelli, MD

Blood (2014) 124 (21): 2703.

https://doi.org/10.1182/blood.V124.21.2703.2703

Published: 2014

Journal Articles

Transient Activation Of Inflammatory Molecules By Epigenetic Modifiers Likely Plays a Role In Expansion Of Transplantable Human Cord Blood Stem/Progenitor Cells

Nadim Mahmud, MD, PhD, Benjamin Petro, BS, Xinmin Li, PhD, Simona Taioli, MS, Alvin Li, John G. Quigley, MD, Donald Lavelle, Ph.D.

Blood (2013) 122 (21): 1170.

https://doi.org/10.1182/blood.V122.21.1170.1170

Published: 2013

Journal Articles

Co-Stimulatory Blockade With CTLA4-Ig Permits Transplantation Of Human Hematopoietic Stem Cells and HLA Incompatible T Cells In NOD/SCID γ Null (NSG) Mouse Model

Annie L. Oh, MD, Dolores Mahmud, Ph.D., Benedetta Nicolini, Ph.D., Nadim Mahmud, MD, PhD, Elisa Bonetti, BS, Pritesh R. Patel, MB, ChB, Damiano Rondelli, MD

Blood (2013) 122 (21): 1999.

https://doi.org/10.1182/blood.V122.21.1999.1999

Published: 2013

Journal Articles

Myeloablative Fludarabine/ IV Busulfan Combined With Linac Based Intentsity Modulated Total Marrow Irradiation (IM-TMI) In Allogeneic Stem Cell Transplant For High Risk Hematologic Malignancies: A Phase I Study

Pritesh R. Patel, MB, ChB, Annie L. Oh, MD, Matthew Koshy, MD, Bulent Aydogan, PhD, Nadim Mahmud, MD, PhD, David Peace, MD, John G. Quigley, MD, Santosh L. Saraf, MD, Enzo DeMasi, MD, Ralph R Weichselbaum, MD, Damiano Rondelli, MD

Blood (2013) 122 (21): 3285.

https://doi.org/10.1182/blood.V122.21.3285.3285

Published: 2013

Journal Articles

Elevated Levels Of γ-Globin Gene Promoter 5-Hydroxymethylcytosine are Associated With Increased DNA Hypomethylation and HbF Expression

Maria Armila Ruiz, BS, Angela Rivers, MD, PhD, Kestis Vaitkus, Tatiana Kouznetsova, M.S., Nadim Mahmud, MD, PhD, Joseph DeSimone, PhD, Donald Lavelle, PH.D.

Blood (2013) 122 (21): 438.

https://doi.org/10.1182/blood.V122.21.438.438

Published: 2013

Journal Articles

Evaluation of Genotoxicity of Chromatin Modifying Agents Expanded Hematopoietic Graft in a Non-Human Primate Model.

Simona Taioli, MS, Benjamin Petro, BS, Sujata Gaitonde, MD, John G. Quigley, MD, Valerie Lindgren, PhD, Manuel Borce, MS, Karen Sweiss, PharmD, Damiano Rondelli, MD, Nadim Mahmud, MD, PhD

Blood (2012) 120 (21): 2994.

https://doi.org/10.1182/blood.V120.21.2994.2994

Published: 2012

Journal Articles

Decreased Pulmonary Function in Asymptomatic Long Term Survivors After Busulfan-Based Myeloablative Allogeneic Hematopoietic Stem Cell Transplant

Annie L. Oh, MD, Pritesh R. Patel, MB, ChB, Santosh Saraf, MD, Karen Sweiss, PharmD, David Peace, MD, John G. Quigley, MD, Nadim Mahmud, MD, PhD, Steven Dudek, MD, Damiano Rondelli, MD

Blood (2012) 120 (21): 4474.

https://doi.org/10.1182/blood.V120.21.4474.4474

Published: 2012

Journal Articles

Possible Reduced Immunogenicity of Chromatin Modifying Agents Expanded Cord Blood Grafts Is Likely Due to STAT3 Inhibition,

Benjamin Petro, BS, Kazumi G Yoshinaga, MS, Dolores Mahmud, PhD, Simona Taioli, MS, Santosh Saraf, MD, Amer Sidani, MD, John G. Quigley, MD, Damiano Rondelli, MD, Nadim Mahmud, MD, PhD

Blood (2011) 118 (21): 4016.

https://doi.org/10.1182/blood.V118.21.4016.4016

Published: 2011

Journal Articles

Ex Vivo Expansion of Human Mobilized Peripheral Blood Stem Cells Using Epigenetic Modifiers

Santosh Saraf, MD, Hiroto Araki, MD, PhD, Benjamin Petro, BS, Kazumi G Yoshinaga, MS, Simona Taioli, MS, Amer Sidani, MD, John G. Quigley, MD, Damiano Rondelli, MD, Nadim Mahmud, MD, PhD

Blood (2011) 118 (21): 1920.

https://doi.org/10.1182/blood.V118.21.1920.1920

Published: 2011

Journal Articles

Anti-Leukemic Activity Is Increased with Low Dose Busulfan and Irradiation: A Preclinical Model

Pritesh R. Patel, MB, ChB, Dolores Mahmud, PhD, Wei Zhang, PhD, Tong Zhou, PhD, Nadim Mahmud, MD, PhD, Ralph R Weichselbaum, MD, Joe GN Garcia, MD, Damiano Rondelli, MD

Blood (2011) 118 (21): 4696.

https://doi.org/10.1182/blood.V118.21.4696.4696

Published: 2011

Journal Articles

Valproic Acid Results In Maintenance but Not Expansion of Transplantable Hematopoietic Stem Cells From Human Umbilical Cord Blood

Hiroto Araki, MD, PhD, Sudhakar Baluchamy, PhD, Benjamin Petro, Mirza Saqib Baig, PhD, Montha Suhangul, MD, John G. Quigley, MD, Naoyuki Katayama, MD, PhD, Nadim Mahmud, MD, PhD

Blood (2010) 116 (21): 827.

https://doi.org/10.1182/blood.V116.21.827.827

Published: 2010

Journal Articles

Clinical Grade Isolation of Regulatory T Cells From G-CSF Mobilized PBSC Improves with Initial Depletion of Monocytes.

Dolores Mahmud, Youngmin Park, Nadim Mahmud, MD, PhD, Damiano Rondelli

Blood (2010) 116 (21): 1176.

https://doi.org/10.1182/blood.V116.21.1176.1176

Published: 2010

Journal Articles

An in-Vivo Model of T Cell-Mediated Rejection of Human Hematopoietic CD34+ Stem Cells Using NOD/SCID γ null (NOG) Mice.

Benedetta Nicolini, Dolores Mahmud, PhD, Nadim Mahmud, MD, PhD, Giuseppina Nucifora, PhD, Damiano Rondelli, MD

Blood (2009) 114 (22): 4474.

https://doi.org/10.1182/blood.V114.22.4474.4474

Published: 2009

Journal Articles

In Vivo Treatment with Chromatin Modifying Agents Dramatically Increases Hematopoietic Stem Cell Numbers.

Benjamin Petro, BS, Hiroto Araki, MD, PhD, John G. Quigley, MD, Damiano Rondelli, MD, Nadim Mahmud, MD, PhD

Blood (2009) 114 (22): 370.

https://doi.org/10.1182/blood.V114.22.370.370

Published: 2009

NARROW

The Cytotoxic Effect of the PARP Inhibitor ABT-888 on Myeloproliferative Neoplasms

In-Vitro and in-Vivo Synergistic Effect of Melphalan and Dual DNA Repair Inhibition in Multiple Myeloma

Targeted Depletion of Amino Acids As a Novel Therapy for Acute Leukemia and Other Cancers: Mechanisms and Countermechanisms

A Phase 1 Study of Total Marrow Irradiation Combined with High-Dose Melphalan for Patients with Relapsed/ Refractory Multiple Myeloma

A Preclinical Non-Human Primate Model to Test Reversible Myeloablation Following IV Busulfan Therapy without Stem Cell Rescue

Preclinical Study for the Use of Abatacept to Prevent Rejection of Allogeneic CD34+ Cells in a Xenograft Model

Alemtuzumab/Low Dose Radiation Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation for Adult Patients with Sickle Cell Disease (SCD)

Transient Activation Of Inflammatory Molecules By Epigenetic Modifiers Likely Plays a Role In Expansion Of Transplantable Human Cord Blood Stem/Progenitor Cells

Co-Stimulatory Blockade With CTLA4-Ig Permits Transplantation Of Human Hematopoietic Stem Cells and HLA Incompatible T Cells In NOD/SCID γ Null (NSG) Mouse Model

Myeloablative Fludarabine/ IV Busulfan Combined With Linac Based Intentsity Modulated Total Marrow Irradiation (IM-TMI) In Allogeneic Stem Cell Transplant For High Risk Hematologic Malignancies: A Phase I Study

Elevated Levels Of γ-Globin Gene Promoter 5-Hydroxymethylcytosine are Associated With Increased DNA Hypomethylation and HbF Expression

Evaluation of Genotoxicity of Chromatin Modifying Agents Expanded Hematopoietic Graft in a Non-Human Primate Model.

Decreased Pulmonary Function in Asymptomatic Long Term Survivors After Busulfan-Based Myeloablative Allogeneic Hematopoietic Stem Cell Transplant

Possible Reduced Immunogenicity of Chromatin Modifying Agents Expanded Cord Blood Grafts Is Likely Due to STAT3 Inhibition,

Ex Vivo Expansion of Human Mobilized Peripheral Blood Stem Cells Using Epigenetic Modifiers

Anti-Leukemic Activity Is Increased with Low Dose Busulfan and Irradiation: A Preclinical Model

Valproic Acid Results In Maintenance but Not Expansion of Transplantable Hematopoietic Stem Cells From Human Umbilical Cord Blood

Clinical Grade Isolation of Regulatory T Cells From G-CSF Mobilized PBSC Improves with Initial Depletion of Monocytes.

An in-Vivo Model of T Cell-Mediated Rejection of Human Hematopoietic CD34+ Stem Cells Using NOD/SCID γ null (NOG) Mice.

In Vivo Treatment with Chromatin Modifying Agents Dramatically Increases Hematopoietic Stem Cell Numbers.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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