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Journal Articles

In Situ Fate Mapping of Native and Stress Myelopoiesis Reveals a Unique Niche for Mono- and Dendritic Cell -Poiesis

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-143123

Published: 2020

Journal Articles

Spatial Mapping of Myelopoiesis Reveals the Bone Marrow Niche for Monocyte Dendritic Cell Progenitors

Jizhou Zhang, Qingqing Wu, PhD, Courtney Johnson, BS, André Olsson, MS, PhD, Anastasiya Slaughter, BA, Margot Lindsay May, BS, Benjamin Weinhaus, BS, Emily Bowers, PhD, James Douglas Engel, PhD, Jean X. Jiang, PhD, Sherry L. Abboud-Werner, PhD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD, Daniel Lucas-Alcaraz, PhD

Blood (2019) 134 (Supplement_1): 528.

https://doi.org/10.1182/blood-2019-128809

Published: 2019

Journal Articles

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Zhaowei Tu, PhD, Chen Wang, MSc, Chuntao Zhao, PhD, Lei Huang, PhD, Nathan Salomonis, PhD, Richard Q Lu, PhD, Yi Zheng, PhD

Blood (2019) 134 (Supplement_1): 1191.

https://doi.org/10.1182/blood-2019-127313

Published: 2019

Journal Articles

The Molecular Basis of Long First Remissions in Normal Karyotype AML Patients

Francesca Ferraro, MD PhD, Christopher A Miller, PhD, Amy Abdalla, Nichole Helton, Nathan Salomonis, PhD, Robert S Fulton, Catrina Fronick, BS, Sharon E Heath, Peter Westervelt, MD PhD, Timothy J Ley, MD

Blood (2019) 134 (Supplement_1): 3827.

https://doi.org/10.1182/blood-2019-122967

Published: 2019

Journal Articles

SKI Controls MDS-Associated Chronic TGFb Signaling, Aberrant Splicing, and Stem Cell Fitness

David Muench, BS, Kyle Ferchen, BS, Chinavenmeni S. Velu, PhD, Kith Pradhan, PhD, Kashish Chetal, MS, Clemencia Colmenares, PhD, Amit Verma, MD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD

Blood (2018) 132 (Supplement 1): 4350.

https://doi.org/10.1182/blood-2018-99-119441

Published: 2018

Journal Articles

Neutropenia-Associated Mutations Differentially Impact Developmental Cell-States

David Muench, BS, Kyle Ferchen, BS, Giang Pham, PhD, Somchai Chutipongtanate, MDPhD, Pankaj Dwivedi, PhD, Stuart Hay, Kashish Chetal, MS, Jayati Mookerjee-Basu, PhD, Kejian Zhang, MD MBA, Kasiani C. Myers, MD, Kristopher Nazor, PhD, Kenneth D Greis, PhD, Dietmar J Kappes, PhD, Sing Sing Way, MDPhD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD

Blood (2018) 132 (Supplement 1): 18.

https://doi.org/10.1182/blood-2018-99-116549

Published: 2018

Journal Articles

A Prognostic Human Splicing Signature That Precurses Leukemia

Meenakshi Venkatasubramanian, BS, Xiaoting Chen, PhD, Kashish Chetal, MS, Aishwarya Kulkarni, MS, Kasiani C. Myers, MD, Matthew T. Weirauch, PhD, H. Leighton Grimes, PhD, Nathan Salomonis, PhD

Blood (2018) 132 (Supplement 1): 877.

https://doi.org/10.1182/blood-2018-99-115000

Published: 2018

Journal Articles

The Erythro-Myeloblastic Island (EMBI): A Hematopoietic Niche Balancing Erythropoiesis and Myelopoiesis

Katie Giger Seu, PhD, Laurel Romano, Julien Papoin, MS, Edward David Muench, Diamantis Konstantinidis, PhD BSc, André Olsson, MSc, PhD, Kashish Chetal, MS, Joel Anne Chasis, MD, Mohandas Narla, DSc, Nathan Salomonis, PhD, H Leighton Grimes, PhD, Lionel Blanc, PhD, Theodosia A. Kalfa, MD PhD

Blood (2018) 132 (Supplement 1): 842.

https://doi.org/10.1182/blood-2018-99-118728

Published: 2018

Journal Articles

MLL-Fusion Leukemia Dependence on MBNL1 Is Associated with Alternative Splicing of Oncogenic Proteins

Arun Gurunathan, MD, Lana S Itskovich, PhD, Jason Clark, MS, Matthew Burwinkel, Nathan Salomonis, PhD, Meenakshi Venkatasubramanian, BS, Kashish Chetal, MS, Lynn Lee, MD, Ashish R Kumar, MD PhD

Blood (2018) 132 (Supplement 1): 3883.

https://doi.org/10.1182/blood-2018-99-112349

Published: 2018

Journal Articles

Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals Role of Cell Cycle in Fate Specification

Yi-Chien Lu, PhD, Diane S. Krause, MD PhD, Juliana Xavier-Ferrucio, PhD, Lin Wang, MS, Nathan Salomonis, PhD, Kashish Chetal, MS, Bruce J. Aronow, PhD, Chad Sanada, PhD, Meenakshi Venkatasubramanian, BS

Blood (2018) 132 (Supplement 1): 3828.

https://doi.org/10.1182/blood-2018-99-119105

Published: 2018

Journal Articles

Severe Congenital Neutropenia-Associated Mutations Reveal Stage-Specific Gfi1-Dependent Checkpoints in Myeloid Development

David Muench, BS, Dietmar J Kappes, PhD, Nathan Salomonis, PhD, Kasiani C. Myers, MD, Lee Grimes

Blood (2017) 130 (Supplement 1): 544.

https://doi.org/10.1182/blood.V130.Suppl_1.544.544

Published: 2017

Journal Articles

Mitochondrial Morphology Controls Hematopoietic Stem Cell Self-Renewal and Confers Them Divisional Memory

Ashwini S. Hinge, PhD, Jingyi He, MD, Eucabeth Mose, BS, Jose Javier, BS, James Bartram, BS, Ellen Fjellman, BS, Hiromi Sesaki, PhD, H Leighton Grimes, PhD, Nathan Salomonis, PhD, Marie-Dominique Filippi, PhD, PhD

Blood (2017) 130 (Supplement 1): 633.

https://doi.org/10.1182/blood.V130.Suppl_1.633.633

Published: 2017

Journal Articles

Integrative Epigenetic and Single-Cell RNA-Seq Profiling of Human Hematopoietic Stem Cells Reveals Epigenetic Reprogramming of Enhancer and Regulatory Elements during Normal Aging

Emmalee Adelman, BA, André Olsson, MSc, PhD, Tingting Qin, PhD, R. Coleman Lindsley, MD PhD, Rafael Bejar, MD PhD, Nathan Salomonis, PhD, Lee Grimes, Maria E. Figueroa, MD

Blood (2017) 130 (Supplement 1): 770.

https://doi.org/10.1182/blood.V130.Suppl_1.770.770

Published: 2017

Journal Articles

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Molly A Smith, Gaurav Choudhary, PhD, Andrea Pellagatti, PhD, Kwangmin Choi, PhD, Tushar Damodar Bhagat, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, Maria Elena S Sampson, Shanisha Gordon, Dagny Von Ahrens, Kith Pradhan, PhD, Ulrich G. Steidl, MDPhD, Robert Booher, PhD, Jacqueline Boultwood, PhD, Amit Verma, MD, Daniel Starczynowski, PhD

Blood (2017) 130 (Supplement 1): 785.

https://doi.org/10.1182/blood.V130.Suppl_1.785.785

Published: 2017

Journal Articles

Single-Cell Transcriptomics of Human Plasma Cells from HLA-Sensitized Patients Reveals Population Heterogeneity and Drug Resistance Adaptations

James Driscoll, MD PhD, Simon Tremblay, PharmD, Nathan Salomonis, PhD, Harinder Singh, PhD, E. Steve Woodle, MD

Blood (2017) 130 (Supplement 1): 1901.

https://doi.org/10.1182/blood.V130.Suppl_1.1901.1901

Published: 2017

Journal Articles

Alternative Splice Variants of IRAK4 That Activate Innate Immune Signaling Are Associated with U2AF1 Mutations in Myelodysplastic Syndrome and Acute Myeloid Leukemia

Molly A Smith, BS, Kwangmin Choi, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, PhD, Daniel T Starczynowski, PhD

Blood (2016) 128 (22): 1531.

https://doi.org/10.1182/blood.V128.22.1531.1531

Published: 2016

Journal Articles

Single Cell RNA seq for Analysis of Cell Fate Decisions

H. Leighton Grimes, PhD, Singh Harinder, PhD, Andre Olsson, PhD, Nathan Salomonis, PhD, Bruce J. Aronow, PhD, Viren Chaudhry, PhD

Blood (2015) 126 (23): SCI-20.

https://doi.org/10.1182/blood.V126.23.SCI-20.SCI-20

Published: 2015

Journal Articles

Identification of the Origin of Eosinophils

Andre Olsson, PhD, Nathan Salomonis, PhD, Harinder Singh, H. Leighton Grimes, PhD

Blood (2015) 126 (23): 886.

https://doi.org/10.1182/blood.V126.23.886.886

Published: 2015

Journal Articles

Long-Lasting Dysregulation of the Hematopoietic Stem Cell Compartment in Obesity

Jung-Mi Lee, PhD, Bryan Goddard, Ashwini S. Hinge, PhD, Bruce J. Aronow, PhD, Nathan Salomonis, PhD, Marie-Dominique Filippi, PhD, H. Leighton Grimes, PhD, Jose A Cancelas, MD PhD, Damien Reynaud, PhD

Blood (2015) 126 (23): 245.

https://doi.org/10.1182/blood.V126.23.245.245

Published: 2015

Journal Articles

Ubiquitin Editing of a Spliceosome Auxiliary Factor By TRAF6 Links Chronic TLR Signaling with Hematopoietic Defects and Myelodysplasia

Jing Fang, MD, PhD, Lyndsey Bolanos, BSc, Kwang-Min Choi, PhD, Xiaona Liu, Ms, Susanne Christie, Shailaja Akunuru, PhD, Rupali Kumar, PhD, Ken Greis, PhD, Peter Stoilov, PhD, Marie-Dominique Filippi, PhD, Jaroslaw P. Maciejewski, MD PhD, Guillermo Garcia-Manero, MD, Matthew Weirauch, PhD, Nathan Salomonis, PhD, Hartmut Geiger, PhD, Yi Zheng, PhD, Daniel Starczynowski, PhD

Blood (2015) 126 (23): 143.

https://doi.org/10.1182/blood.V126.23.143.143

Published: 2015

NARROW

In Situ Fate Mapping of Native and Stress Myelopoiesis Reveals a Unique Niche for Mono- and Dendritic Cell -Poiesis

Spatial Mapping of Myelopoiesis Reveals the Bone Marrow Niche for Monocyte Dendritic Cell Progenitors

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

The Molecular Basis of Long First Remissions in Normal Karyotype AML Patients

SKI Controls MDS-Associated Chronic TGFb Signaling, Aberrant Splicing, and Stem Cell Fitness

Neutropenia-Associated Mutations Differentially Impact Developmental Cell-States

A Prognostic Human Splicing Signature That Precurses Leukemia

The Erythro-Myeloblastic Island (EMBI): A Hematopoietic Niche Balancing Erythropoiesis and Myelopoiesis

MLL-Fusion Leukemia Dependence on MBNL1 Is Associated with Alternative Splicing of Oncogenic Proteins

Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals Role of Cell Cycle in Fate Specification

Severe Congenital Neutropenia-Associated Mutations Reveal Stage-Specific Gfi1-Dependent Checkpoints in Myeloid Development

Mitochondrial Morphology Controls Hematopoietic Stem Cell Self-Renewal and Confers Them Divisional Memory

Integrative Epigenetic and Single-Cell RNA-Seq Profiling of Human Hematopoietic Stem Cells Reveals Epigenetic Reprogramming of Enhancer and Regulatory Elements during Normal Aging

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Single-Cell Transcriptomics of Human Plasma Cells from HLA-Sensitized Patients Reveals Population Heterogeneity and Drug Resistance Adaptations

Alternative Splice Variants of IRAK4 That Activate Innate Immune Signaling Are Associated with U2AF1 Mutations in Myelodysplastic Syndrome and Acute Myeloid Leukemia

Single Cell RNA seq for Analysis of Cell Fate Decisions

Identification of the Origin of Eosinophils

Long-Lasting Dysregulation of the Hematopoietic Stem Cell Compartment in Obesity

Ubiquitin Editing of a Spliceosome Auxiliary Factor By TRAF6 Links Chronic TLR Signaling with Hematopoietic Defects and Myelodysplasia

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American Society of Hematology

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American Society of Hematology

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