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Nikhil C. Munshi, M.D.
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Journal Articles

Interim Results of An Ongoing Clinical Study Suggests Efficacy and Improved Toxicity Profile with Once a Week Bortezomib with Dexamethasone In Newly Diagnosed Multiple Myeloma Patients with Older Age and Co-Morbidities

Nikhil C. Munshi, M.D., Saem Lee, B.A., Suman Kambhampati, M.D., Abid Mohiuddin, M.D., Michal Rose, M.D., Caroline Behler, M.D., Andrew Han, B.A., Yvonne Efebera, M.D., Antoun Houranieh, RPh., M.S., Ph.D., Mary T. Brophy, M.D., Abraham Zimelman, M.D., Rao H Prabhala, Ph.D., Hussain I. Saba, M.D, Ph.D, Catherine Klein, M.D., Paulette Mehta, M.D, MPH, Teresa Hayes, M.D., David Roodman, M.D, Ph.D, Alan K. Lichtenstein, M.D.
Journal: Blood
Blood (2010) 116 (21): 3061.
https://doi.org/10.1182/blood.V116.21.3061.3061
Published: 2010
Journal Articles

Bone Marrow Niche Down-Regulates Mir-30 In Multiple Myeloma Cells to Promote Cancer Progression and Cancer Initiation by Targeting BCL9/Wnt Pathway.

Jian-Jun Zhao, M.D., Ph.D., Jianhong Lin, M.D., Zhangbo Chu, M.D., Qi Wang, Ph.D., Kohichi Takada, M.D., Ph.D., Mala Mani, Ph.D., Bryan Ciccarelli, Teru Hideshima, M.D., Ph.D., Tai Yu-Tzu, Ph.D., Jianguo Tao, MD, PhD, Steven P. Treon, MD, PhD, Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D., Ruben Carrasco, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1569.
https://doi.org/10.1182/blood.V116.21.1569.1569
Published: 2010
Journal Articles

Combination of Nab -Rapamycin and Perifosine Induces Synergistic Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in Multiple Myeloma (MM)

Diana Cirstea, M.D., Teru Hideshima, M.D., Ph.D., Samantha Pozzi, M.D., Sonia Vallet, M.D., Hiroshi Ikeda, M.D., Ph.D., Loredana Santo, M.D., Scott Rodig, M.D., Ph.D., Nileshwari Vaghela, M.B.S, Treeve Currie, Yutaka Okawa, M.D., Ph.D., Gaurav Chhetri, Chirayu G. Patel, Giulia Perrone, M.D., Gullu Gorgun, Ph.D., Elisabetta Calabrese, M.D., Voung Trieu, Neil Desai, Ph.D., Peter Sportelli, Nikhil C. Munshi, M.D., Kenneth C Anderson, M.D., Noopur Raje, M.D.
Journal: Blood
Blood (2008) 112 (11): 3663.
https://doi.org/10.1182/blood.V112.11.3663.3663
Published: 2008
Journal Articles

Activation of B-Cell Maturation Antigen (BCMA) on Human Multiple Myeloma Cells by a Proliferation-Inducing Ligand (APRIL) Promotes Myeloma Cell Function in the Bone Marrow Microenvironment.

Merav Leiba, M.D., Jiangchun Xu, M.D., Ph.D., Weihua Song, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Jennifer Kordich, M.S., Linda Cassiano, B.A., Klaus Podar, M.D., Ph.D., Dharminder Chauhan, Ph.D., Teru Hideshima, M.D., Ph.D., Nikhil C. Munshi, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Yu-Tzu Tai, PhD
Journal: Blood
Blood (2007) 110 (11): 1503.
https://doi.org/10.1182/blood.V110.11.1503.1503
Published: 2007
Journal Articles

Genomic Evolution of Multiple Myeloma In Vivo over Time.

Yu-Tzu Tai, PhD, Benjamin King, B.S., Cheng Li, Ph.D., XianFeng Li, M.S., Peter Burger, B.S., Weihua Song, M.D., Masood Shammas, Ph.D., Robert Schlossman, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Nikhil C. Munshi, M.D.
Journal: Blood
Blood (2006) 108 (11): 3400.
https://doi.org/10.1182/blood.V108.11.3400.3400
Published: 2006
Journal Articles

The BAFF Inhibitor AMG523 Blocks Adhesion and Survival of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment: Clinical Implication.

Yu-Tzu Tai, PhD, Jiangchun Xu, M.D., Xian-Feng Li, M.S., Iris Breitkreutz, M.D., Klaus Podar, M.D. Ph.D., Teru Hideshima, M.D. Ph.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3452.
https://doi.org/10.1182/blood.V108.11.3452.3452
Published: 2006
Journal Articles

Inhibition of ERK1/2 Activity by the MEK1/2 Inhibitor AZD6244 (ARRY-142886) Induces Human Multiple Myeloma Cell Apoptosis in the Bone Marrow Microenvironment: A New Therapeutic Strategy for MM.

Yu-Tzu Tai, PhD, Xian-Feng Li, M.S., Iris Breitkreutz, M.D., Weihua Song, M.D., Peter Burger, B.S., Matthew Rumizen, Teru Hideshima, M.D. Ph.D., Klaus Podar, M.D. Ph.D., Irene Ghobrial, M.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3460.
https://doi.org/10.1182/blood.V108.11.3460.3460
Published: 2006
Journal Articles

The MEK1/2 Inhibitor AZD6244 (ARRY-142886) Downregulates Constitutive and Adhesion-Induced c- MAF Oncogene Expression and Its Downstream Targets in Human Multiple Myeloma.

Yu-Tzu Tai, PhD, Giovanni Tonon, Ph.D., Xian-Feng Li, M.S., Matthew Rumizen, Weihua Song, M.D., Aileen Morrison, B.S., Peter Burger, B.S., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3463.
https://doi.org/10.1182/blood.V108.11.3463.3463
Published: 2006
Journal Articles

Killing of Drug-Sensitive and Resistant Myeloma Cells and Disruption of Their Bone Marrow Stromal Interaction by HuLuc63, a Novel Humanized Anti-CS1 Monoclonal Antibody.

Yu-Tzu Tai, PhD, Weihua Song, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Robert Schlossman, M.D., Audie Rice, Ph.D., Anne van Abbema, Ph.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Daniel Afar, Ph.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3470.
https://doi.org/10.1182/blood.V108.11.3470.3470
Published: 2006
Journal Articles

Distinct Dynamic Profiles for NPI-0052-And Bortezomib-Induced Apoptosis in Multiple Myeloma.

Dharminder Chauhan, PhD, Ajita Singh, Ph.D, Mugdha Velankar, M.S, Teru Hideshima, Ph.D, Huib Ovaa, Ph.D, Celia Berkers, M.S, Giada Bianchi, Ph.D, Roberto Sitia, M.D., Nikhil C. Munshi, M.D., Paul Richardson, M.D., Michael A. Palladino, Ph.D, Kenneth C. Anderson, M.D
Journal: Blood
Blood (2006) 108 (11): 3396.
https://doi.org/10.1182/blood.V108.11.3396.3396
Published: 2006
Journal Articles

A Fully Human Antagonist Anti-CD40 Antibody Triggers Significant Antitumor Activity Against Human Multiple Myeloma.

Yu-Tzu Tai, Ph.D., Xian-Feng Li, M.S., Xia Tong2, M.S., Laurence Catley, M.D., Daniel Santos, M.D., Olivier Tournilhac, M.D., Ph.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Mohammad Luqman2, Ph.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2004) 104 (11): 2414.
https://doi.org/10.1182/blood.V104.11.2414.2414
Published: 2004
Journal Articles

Induction of Multiple Myeloma-Specific Cytotoxic T Lymphocytes Using HLA-A2.1-Specific CD19 and CD20 Peptides.

Jooeun Bae, Ph.D., Jeff A. Martinson, B.S., Hans G. Klingemann, M.D., Steven Treon, M.D., Kenneth C. Anderson, M.D., Nikhil C. Munshi, M.D.
Journal: Blood
Blood (2004) 104 (11): 2477.
https://doi.org/10.1182/blood.V104.11.2477.2477
Published: 2004
Journal Articles

Tumor Antigen Immunization of Sibling Stem Cell Transplant Donors in Multiple Myeloma.

Sattva S. Neelapu, M.D., Nikhil C. Munshi, M.D., Sundar Jagannath, M.D., Thelma M. Watson, R.N., Robin Pennington, Bart Barlogie, M.D., Ph.D., Larry W. Kwak, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 3340.
https://doi.org/10.1182/blood.V104.11.3340.3340
Published: 2004
Journal Articles

Honokiol Overcomes Conventional Drug Resistance in Human Multiple Myeloma.

Kenji Ishitsuka, M.D., Ph.D, Teru Hideshima, M.D., Ph.D, Makoto Hamasaki, M.D., Ph.D, Raje Noopur, M.D., Ph.D, Kumar Shaji, M.D., Ph.D, Hiromasa Hideshima, Norihiko Shiraishi, Ph.D, Paul Richardson, M.D., Ph.D, Nikhil C. Munshi, M.D., Ph.D, Dharminder Chauhan, Ph.D, Jack Arbiser, M.D., Ph.D, Kenneth C. Anderson, M.D., Ph.D
Journal: Blood
Blood (2004) 104 (11): 1488.
https://doi.org/10.1182/blood.V104.11.1488.1488
Published: 2004
Journal Articles

Enhanced Cytotoxicity of Monoclonal Antibody SGN-40 and Immunomodulatory Drug IMiD3 Against Human Multiple Myeloma.

Yu-Tzu Tai, Ph.D., Laurence Catley, M.D., Xian-Feng Li, M.S., Makoto Hamasaki, M.D., Ph.D., Klaus Podar, M.D., Ph.D., Teru Hideshima, M.D., Ph.D., Dharminder Chauhan, Ph.D., Robert Schlossman, M.D., Paul Richardson, M.D., Steven P. Streon, M.D., Ph.D., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2004) 104 (11): 1498.
https://doi.org/10.1182/blood.V104.11.1498.1498
Published: 2004