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Oliver Grottke, MD
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Journal Articles

Reversal of Apixaban Anticoagulation with Reduced Doses of Andexanet Alfa in a Porcine Polytrauma Model

Oliver Grottke, MD PhD MPH, Necib Akman, MD, Till Braunschweig, MD, Pamela B. Conley, PhD, Rolf Rossaint, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2456.
https://doi.org/10.1182/blood-2018-99-114426
Published: 2018
Journal Articles

Comparison of Second and First Generation of Andexanet Alfa in a Porcine Polytrauma Model with Apixaban Anticoagulation

Oliver Grottke, MD PhD MPH, Necib Akman, MD, Till Braunschweig, MD, Pamela B. Conley, PhD, Rolf Rossaint, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3778.
https://doi.org/10.1182/blood-2018-99-114542
Published: 2018
Journal Articles

Blood Loss in Rivaroxaban Anticoagulated Pigs with Severe Polytrauma Is Significantly Reduced By Early Therapy with Prothrombin Complex Concentrate

Oliver Grottke, MD PhD MPH, Necib Akman, MD, Till Braunschweig, MD, Markus Honickel, MD, Hugo ten Cate, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2392.
https://doi.org/10.1182/blood.V130.Suppl_1.2392.2392
Published: 2017
Journal Articles

Markers of Thromboembolic Risk Were Insignificantly Affected By Either Intraosseous or Intravenous Idarucizumab in a Dabigatran-Anticoagulated Porcine Polytrauma Model

Markus Honickel, MD, Akman Necib, MD, Hugo ten Cate, MD PhD, Rolf Rossaint, MD Prof, Oliver Grottke, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2623.
https://doi.org/10.1182/blood.V128.22.2623.2623
Published: 2016
Journal Articles

Reversal of Trauma-Induced Bleeding and Anticoagulation with a Dabigatran-Specific Antidote (idarucizumab) As Assessed By Shed and Washed Blood Tests in a Pig Model of Supratherapeutic Anticoagulation and Trauma

Oliver Grottke, MD PhD, Markus Honickel, MD, Johanna Schurer, Joanne van Ryn, PhD
Journal: Blood
Blood (2014) 124 (21): 4268.
https://doi.org/10.1182/blood.V124.21.4268.4268
Published: 2014
Journal Articles

Prothrombin Complex Concentrate in Combination with Fibrinogen Plus Tranexamic Acid Is More Effective Than Mono-Therapy with Prothrombin Complex Concentrate in a Dabigatran Anticoagulation Experimental Polytrauma Model

Oliver Grottke, MD PhD, Markus Honickel, MD, Henri M.H. Spronk, PhD, Hugo ten Cate, Joanne van Ryn, PhD, Rolf Rossaint, MD
Journal: Blood
Blood (2014) 124 (21): 346.
https://doi.org/10.1182/blood.V124.21.346.346
Published: 2014
Journal Articles

Ex Vivo Prothrombin Complex Concentrates and a Specific Antidote Are Effective In Reversing Dabigatran-Induced Coagulopathy In Pigs

Joanne van Ryn, PhD, Henri M.H. Spronk, PhD, Rolf Rossaint, MD, Oliver Grottke, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2387.
https://doi.org/10.1182/blood.V122.21.2387.2387
Published: 2013
Journal Articles

Resuscitation With Different Volume Expanders Does Not Influence Coagulation After Antidoting Dabigatran With Its Specific Fab In a Pig Model Of Hemorrhagic Shock

Henri M.H. Spronk, PhD, Joanne van Ryn, PhD, Christian Zentai, Hugo ten Cate, MD, PhD, Rolf Rossaint, MD, Oliver Grottke, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3649.
https://doi.org/10.1182/blood.V122.21.3649.3649
Published: 2013
Journal Articles

Thrombin Generation Capacity of Prothrombin Complex Concentrate in an in Vitro Dilutional Model

Henri M.H. Spronk, PhD, Rolf Rossaint, MD, Henskens M.C. Yvonne, Rene van Oerle, Hugo Ten Cate, MD, PhD, Oliver Grottke, MD
Journal: Blood
Blood (2012) 120 (21): 4380.
https://doi.org/10.1182/blood.V120.21.4380.4380
Published: 2012