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    Otto C Boerman, PhD
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    Journal Articles

    Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase

    Free
    Laurens T Van Der Meer, PhD, Samantha YA Terry, PhD, Dorette van Ingen Schenau, MSc, Kiki Andree, MSc, Gerben M Franssen, BSc, Debbie Roeleveld, MSc, Bart Metselaar, PhD, Thomas Reinheckel, PhD, Peter M Hoogerbrugge, MD PhD, Otto C Boerman, PhD, Frank N van Leeuwen, PhD
    Journal: Blood
    Blood (2015) 126 (23): 3768.
    https://doi.org/10.1182/blood.V126.23.3768.3768
    Published: 2015
    Journal Articles

    The Therapeutic Protein Asparaginase Is Efficiently Cleared By Bone Barrow and Spleen Resident Macrophages

    Free
    Laurens T van der Meer, PhD, Samantha YA Terry, PhD, Dorette S van IngenSchenau, MSc, Kiki C Andree, MSc, Peter M Hoogerbrugge, MD PhD, Otto C Boerman, PhD, Frank N van Leeuwen, PhD
    Journal: Blood
    Blood (2014) 124 (21): 3630.
    https://doi.org/10.1182/blood.V124.21.3630.3630
    Published: 2014

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