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Journal Articles

Role of Autoantigen Induced-B-Cell Receptor Internalization and Its Inhibition for the Biology and Survival of Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Patryk Gorniak, Ondrej Havránek, Anna Polak, Przemyslaw Juszczynski

Blood (2023) 142 (Supplement 1): 4141.

https://doi.org/10.1182/blood-2023-187046

Published: 2023

Journal Articles

MEN1703-Mediated PIM Kinases Inhibition Impairs Protumoral and Immunosuppressive Phenotype and Functions of Macrophages in Classical Hodgkin Lymphoma

Maciej Szydlowski, Filip Garbicz, Ewa Kurtz, Justyna Żurańska, Michał Seweryn, Michał Pawlak, Patryk Górniak, Kamil Sokół, Anna Szumera-Ciećkiewicz, Monika Kawecka, Daria Owczarek, Beata Puton, Monika Prochorec-Sobieszek, Daniela Bellarosa, Michał Kurlapski, Jan Zaucha, Paweł Wołkow, Przemyslaw Juszczynski

Blood (2022) 140 (Supplement 1): 6441–6442.

https://doi.org/10.1182/blood-2022-156894

Published: 2022

Journal Articles

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Blood (2020) 136 (Supplement 1): 33–34.

https://doi.org/10.1182/blood-2020-134778

Published: 2020

Journal Articles

SIRT1 and HSP90alpha Are Functionally Linked and Control Mitotic Chromosome Segregation and Cell Viability in a Subset of Dlbcls

Emilia Bialopiotrowicz, PhD, Monika Noyszewska-Kania, MSc, Ewa Jabłońska, PhD, Tomasz Sewastianik, PhD, Monika Stańczak, Msc, Anna Szumera-Ciećkiewicz, MD PhD, Katarzyna Borg, PhD, Aleksandra Bluszcz, Msc, Sonia Dębek, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Polak, PhD, Patryk Górniak, PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-139319

Published: 2020

Journal Articles

Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner

Maciej Szydlowski, PhD, Michał Pawlak, PhD, Filip Garbicz, MD, Patryk Górniak, PhD, Justyna Żurańska, PhD, Magdalena Król, PhD, Bartłomiej Taciak, Maciej Białasek, Anna Szumera-Ciećkiewicz, MD PhD, Kamil Sokół, Monika Stańczak, Msc, Daria Owczarek, Monika Prochorec-Sobieszek, MD PhD, Anna Polak, PhD, Emilia Bialopiotrowicz, PhD, Michał Kurlapski, Jan Zaucha, MDPhD, Paweł Wołkow, PhD, Przemyslaw Juszczynski, MD PhD

Blood (2020) 136 (Supplement 1): 30.

https://doi.org/10.1182/blood-2020-134886

Published: 2020

Journal Articles

Predictive Significance of Selected Gene Mutations Identified Using Next Generation Sequencing in Relapsed and Refractory Chronic Lymphocytic Leukemia Patients Treated with Ibrutinib

Marcin M Machnicki, MSc, Patryk Górniak, Monika Pepek, MSc, Agnieszka Szymczyk, Elżbieta Iskierka-Jażdżewska, Pawel Steckiewicz, Aleksandra Bluszcz, Malgorzata Rydzanicz, PhD, Marek Hus, Rafal Ploski, MD PhD, Przemyslaw Juszczynski, Prof., MD PhD, Tomasz Stoklosa, MD PhD, Krzysztof Jamroziak, MD PhD, Bartosz Pula

Blood (2019) 134 (Supplement_1): 5456.

https://doi.org/10.1182/blood-2019-124693

Published: 2019

Journal Articles

Downregulation of Deptor By MiR-155 Promotes Cell Survival through Activation of PI3K/AKT and NFkB Signaling in ABC-Type Diffuse Large B-Cell Lymphomas

Ewa Jablonska, PhD, Patryk Gorniak, PhD, Weronika Prusisz, MSc, Przemyslaw Kiliszek, PhD, Maciej Szydlowski, PhD, Tomasz Sewastianik, PhD, Emilia Bialopiotrowicz, PhD, Anna Polak, PhD, Monika Prochorec-Sobieszek, MD PhD Prof, Anna Szumera-Cieckiewicz, MD PhD, Krzysztof Warzocha, Przemyslaw Juszczynski, MD PhD

Blood (2016) 128 (22): 1761.

https://doi.org/10.1182/blood.V128.22.1761.1761

Published: 2016

Journal Articles

Microenvironment-Induced Expression of PIM Kinases Supports Chronic Lymphocytic Leukemia Cells Survival and Promotes CXCR4-mTOR Pathway Dependent Migration

Blood (2016) 128 (22): 3239.

https://doi.org/10.1182/blood.V128.22.3239.3239

Published: 2016

Journal Articles

Functional Link Between Heat Shock Protein HSP90alpha and Sirtuin 1 (SIRT1) in the Pathogenesis of Diffuse Large B Cell Lymphoma

Emilia Bialopiotrowicz, PhD, Tomasz Sewastianik, PhD, Monika Noyszewska-Kania, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Patryk Gorniak, PhD, Anna Polak, PhD, Przemyslaw Kiliszek, PhD, Krzysztof Warzocha, Przemyslaw Juszczynski, MD PhD

Blood (2016) 128 (22): 4120.

https://doi.org/10.1182/blood.V128.22.4120.4120

Published: 2016

Journal Articles

FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas

Maciej Szydlowski, Przemyslaw Kiliszek, Tomasz Sewastianik, Ewa Jablonska, Emilia Bialopiotrowicz, Patryk Gorniak, Anna Polak, Sergiusz Markowicz, Eliza Nowak, Monika A. Grygorowicz, Monika Prochorec-Sobieszek, Anna Szumera-Cieckiewicz, Agata Malenda, Ewa Lech-Maranda, Krzysztof Warzocha, Przemyslaw Juszczynski

Blood (2016) 127 (6): 739–748.

https://doi.org/10.1182/blood-2015-06-654111

Published: 2016

Includes: Supplemental data

Journal Articles

FOXO1 Activation Is an Effector of SYK and AKT Inhibition in Tonic BCR Signal-Dependent Diffuse Large B-Cell Lymphomas

Przemyslaw Kiliszek, MSc, Maciej Szydlowski, PhD, Tomasz Sewastianik, MSc, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Anna Polak, MSc, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Agata Malenda, MD PhD, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 314.

https://doi.org/10.1182/blood.V126.23.314.314

Published: 2015

Journal Articles

Activity of PIM Kinases in Chronic Lymphocytic Leukemia Modulates Tumor Cell Survival and Stromal Interactions through a Pleiotropic Mechanism Involving Modulation of CXCR4 - mTOR Pathway

Blood (2015) 126 (23): 1549.

https://doi.org/10.1182/blood.V126.23.1549.1549

Published: 2015

Journal Articles

HIF1-Alpha and MYC Transcription Factor Signatures in B-Cell Acute Lymphoblastic Leukemia Are Associated with Positive Minimal Residual Disease Status: Therapeutic Implications

Tomasz Sewastianik, MSc, Patryk Gorniak, PhD, Przemyslaw Kiliszek, MSc, Anna Polak, MSc, Emilia Bialopiotrowicz, PhD, Ewa Jablonska, PhD, Maciej Szydlowski, PhD, Ewa Lech-Maranda, MD PhD, Katarzyna Borg, PhD, Hanna Makuch-Lasica, MSc, Adam Zabek, MSc, Piotr Mlynarz, PhD, Tomasz Stoklosa, MD PhD, Sebastian Giebel, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 1436.

https://doi.org/10.1182/blood.V126.23.1436.1436

Published: 2015

Journal Articles

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

Anna Polak, MSc, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Dominika Nowis, MDPhD, Jakub Golab, MD PhD, Sebastian Giebel, MD PhD, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 4917.

https://doi.org/10.1182/blood.V126.23.4917.4917

Published: 2015

Journal Articles

FOXO1-p300-Txn Circuit Regulates Oxidative Stress Responses in Diffuse Large B-Cell Lymphomas Characterized By Enhanced Oxidative Phosphorylation

Tomasz Sewastianik, MSc, Maciej Szydlowski, PhD, Emilia Bialopiotrowicz, PhD, Ewa Jablonska, PhD, Przemyslaw Kiliszek, MSc, Anna Polak, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Tomasz S. Kaminski, MSc, Patryk Gorniak, PhD, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 466.

https://doi.org/10.1182/blood.V126.23.466.466

Published: 2015

Journal Articles

MiR-155 Amplifies AKT and NFkB Signaling By Targeting Multiple Regulators of BCR Signal in DLBCL

Ewa Jablonska, PhD, Patryk Gorniak, PhD, Weronika Prusisz, MSc, Przemyslaw Kiliszek, MSc, Maciej Szydlowski, PhD, Tomasz Sewastianik, MSc, Emilia Bialopiotrowicz, PhD, Anna Polak, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 2455.

https://doi.org/10.1182/blood.V126.23.2455.2455

Published: 2015

Journal Articles

Surface Expression of CRLF2 Protein Is Associated with Lower Minimal Residual Disease (MRD) Among Children with IKZF1- deleted Acute Lymphoblastic Leukemia (ALL)

Agata Pastorczak, MDPhD, Lukasz Sedek, PhD, Marcin Braun, MD, Joanna Madzio, MSc, Alicja Sonsala, MSc, Marta Bielska, MSc, Joanna Taha, PhD, Patryk Gorniak, PhD, Edyta Ulinska, MD, Michal Matysiak, MD PhD, Katarzyna Derwich, MDPhD, Monika Lejman, PhD, Jerzy Kowalczyk, MDPhD, Wanda Badowska, MDPhD, Maciej Niedzwiecki, MD, Bernarda Kazanowska, MDPhD, Tomasz Szczepanski, MD PhD, Wojciech Mlynarski, MDPhD

Blood (2014) 124 (21): 2400.

https://doi.org/10.1182/blood.V124.21.2400.2400

Published: 2014

NARROW

Role of Autoantigen Induced-B-Cell Receptor Internalization and Its Inhibition for the Biology and Survival of Diffuse Large B-Cell Lymphoma (DLBCL) Cells

MEN1703-Mediated PIM Kinases Inhibition Impairs Protumoral and Immunosuppressive Phenotype and Functions of Macrophages in Classical Hodgkin Lymphoma

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

SIRT1 and HSP90alpha Are Functionally Linked and Control Mitotic Chromosome Segregation and Cell Viability in a Subset of Dlbcls

Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner

Predictive Significance of Selected Gene Mutations Identified Using Next Generation Sequencing in Relapsed and Refractory Chronic Lymphocytic Leukemia Patients Treated with Ibrutinib

Downregulation of Deptor By MiR-155 Promotes Cell Survival through Activation of PI3K/AKT and NFkB Signaling in ABC-Type Diffuse Large B-Cell Lymphomas

Microenvironment-Induced Expression of PIM Kinases Supports Chronic Lymphocytic Leukemia Cells Survival and Promotes CXCR4-mTOR Pathway Dependent Migration

Functional Link Between Heat Shock Protein HSP90alpha and Sirtuin 1 (SIRT1) in the Pathogenesis of Diffuse Large B Cell Lymphoma

FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas

FOXO1 Activation Is an Effector of SYK and AKT Inhibition in Tonic BCR Signal-Dependent Diffuse Large B-Cell Lymphomas

Activity of PIM Kinases in Chronic Lymphocytic Leukemia Modulates Tumor Cell Survival and Stromal Interactions through a Pleiotropic Mechanism Involving Modulation of CXCR4 - mTOR Pathway

HIF1-Alpha and MYC Transcription Factor Signatures in B-Cell Acute Lymphoblastic Leukemia Are Associated with Positive Minimal Residual Disease Status: Therapeutic Implications

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

FOXO1-p300-Txn Circuit Regulates Oxidative Stress Responses in Diffuse Large B-Cell Lymphomas Characterized By Enhanced Oxidative Phosphorylation

MiR-155 Amplifies AKT and NFkB Signaling By Targeting Multiple Regulators of BCR Signal in DLBCL

Surface Expression of CRLF2 Protein Is Associated with Lower Minimal Residual Disease (MRD) Among Children with IKZF1- deleted Acute Lymphoblastic Leukemia (ALL)

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American Society of Hematology

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American Society of Hematology

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