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Peter H Schafer, PhD
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Journal Articles

Absence Of Mutation In Cereblon (CRBN) and DNA Damage Binding Protein 1 (DDB1) Genes In Myeloma Cells and Patients and Its Clinical Significance

Anjan Thakurta, PhD, Anita K Gandhi, PhD, Michelle Waldman, MS, Chad C. Bjorklund, Ph.D., Suzanne Lentzsch, MD, PhD, Stephen A Schey, MD, Yolanda Calle, PhD, Rajani Chelliah, BSc, MSc, Robert Z. Orlowski, M.D., Ph.D, Anup Madan, PhD, Yuhong Ning, Derek Mendy, B.S., Antonia Lopez-Girona, PhD, Peter H Schafer, PhD, Herve Avet-Loiseau, MD, Rajesh Chopra, MD
Journal: Blood
Blood (2013) 122 (21): 3139.
https://doi.org/10.1182/blood.V122.21.3139.3139
Published: 2013
Journal Articles

CC-122 Is a Novel Pleiotropic Pathway Modifier with Potent in Vitro Immunomodulatory and Anti-Angiogenic Properties and in Vivo Anti-Tumor Activity in Hematological Cancers.

Anita K Gandhi, PhD, Derek Mendy, BS, Anastasia Parton, BA, Lei Wu, MS, ECFMG, Jolanta Kosek, BA, Ling-Hua Zhang, PhD, Lori Capone, BS, Antonia Lopez-Girona, PhD, Peter H Schafer, PhD, Rajesh Chopra, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2963.
https://doi.org/10.1182/blood.V120.21.2963.2963
Published: 2012
Journal Articles

Targeting Cereblon with the High Affinity Immunomodulatory Compound CC-220: A Novel Therapeutic Agent for B Cell Dyscrasias

Peter H Schafer, PhD, Emily Rychak, PhD, Derek Mendy, BS, Anastasia Parton, BA, Lori Capone, BS, Antonia Lopez-Girona, PhD, Jilly F Evans, PhD, Tom O Daniel, MD, PhD, Rajesh Chopra, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1055.
https://doi.org/10.1182/blood.V120.21.1055.1055
Published: 2012
Journal Articles

Inhibition of B Cell Differentiation to the Plasmablast and Plasma Cell Lineage by CC-220, a Potent Modulator of the CRBN E3 Ubiquitin Ligase Complex

Peter H Schafer, PhD, Lori Capone, BS, Lei Wu, MS, ECFMG, Rajesh Chopra, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3279.
https://doi.org/10.1182/blood.V120.21.3279.3279
Published: 2012
Journal Articles

Lenalidomide Efficacy in Activated B-Cell-Like Subtype Diffuse Large B-Cell Lymphoma Is Dependent Upon IRF4 and Cereblon Expression

Ling-Hua Zhang, PhD, Jolanta Kosek, BA, Maria Wang, Ph.D., Carla Heise, PhD, Peter H Schafer, PhD, Rajesh Chopra, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3287.
https://doi.org/10.1182/blood.V120.21.3287.3287
Published: 2012
Journal Articles

Detection and Quantification of Cereblon Protein and mRNA in Multiple Myeloma Cell Lines and Primary CD138 + multiple Myeloma Cells

Anita K Gandhi, PhD, Herve Avet-Loiseau, MD, Michelle Waldman, MS, Anjan Thakurta, PhD, Sharon L Aukerman, PhD, Gengxin Chen, PhD, Derek Mendy, BS, Emily Rychak, PhD, Karen Miller, Svetlana Gaidarova, MS, Michael Gonzales, Brian Cathers, PhD, Peter H Schafer, PhD, Tom O Daniel, MD, PhD, Antonia Lopez-Girona, PhD, Rajesh Chopra, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 4043.
https://doi.org/10.1182/blood.V120.21.4043.4043
Published: 2012
Journal Articles

Lenalidomide Shuts Down the Translational Machinery in Multiple Myeloma Cells Resulting in Down-Regulation of Critical Transcription Factors Such as C/EBPβ and IRF4.

Shirong Li, PhD, Rekha Pal, PhD, Deborah L Galson, Ph.D., Peter H Schafer, PhD, Hongjiao Ouyang, DDS, PhD, Markus Y Mapara, MD, PhD, Suzanne Lentzsch, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1844.
https://doi.org/10.1182/blood.V114.22.1844.1844
Published: 2009
Journal Articles

Lenalidomide Displays Anti-Proliferative Activity and Combination Effects with Chemotherapeutic Agents Against a Burkitt’s Lymphoma Cell Line.

Anita K. Gandhi, PhD, Jian Kang, BS, Ling-Hua Zhang, PhD, Blake Bartlett, PhD, Peter H. Schafer, PhD, David I. Stirling, PhD
Journal: Blood
Blood (2007) 110 (11): 4516.
https://doi.org/10.1182/blood.V110.11.4516.4516
Published: 2007