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Pierre de la Grange, PhD
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Journal Articles

Efficacy of ABT-737, a BCL-2 Inhibitor, in an NRAS/BCL2 Mouse Model of High Risk Myelodysplasia (HR-MDS) By Targeting Pathways Identified By Gene Expression Profiling

Rose Ann Padua, PhD, Petra Gorombei, MSc, Stéphanie Beurlet, DMV, PhD, Nader Omidvar, PhD, Satyananda Patel, PhD, Laura Guerenne, MSc, Carole Le Pogam, PhD, Niclas Setterblad, PhD, Pierre de la Grange, PhD, Fabien Guidez, PhD, Christophe Le Boeuf, PhD, Anne Janin, MD PhD, Maria-Elena Noguera, MD, Laure Sarda-Mantel, MD PhD, Pascal Merlet, MD, Robert West, PhD, Marika Pla, PhD, Pierre Fenaux, MD PhD, Patricia Krief, PhD, Christine Chomienne, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3249.
https://doi.org/10.1182/blood.V124.21.3249.3249
Published: 2014
Journal Articles

BCL-2 Inhibition with ABT-737 Prolongs Survival in an NRAS/BCL2-Mediated MOUSE MODEL of Myelodyspastic Syndrome (MDS) Progressing to ACUTE Myelogenous Leukemia (AML) by Targeting Leukemia Initiating CELLS

Petra Gorombei, MSc, Beurlet Stephanie, DMV, PhD, Nader Omidvar, PhD, Krief Patricia, PhD, Le Pogam Carole, MSc, Pierre de la Grange, PhD, Leboeuf Christophe, MD, PhD, Anne Janin, MD, PhD, Noguera Maria-Elena, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Pla Marika, PhD, West Robert, PhD, Pierre Fenaux, MD, PhD, Christine Chomienne, MD, PhD, Rose Ann Padua, PhD
Journal: Blood
Blood (2012) 120 (21): 678.
https://doi.org/10.1182/blood.V120.21.678.678
Published: 2012
Journal Articles

ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival

Rose Ann Padua, PhD, Stephanie Beurlet, DMV, Patricia Krief, PhD, Nader Omidvar, PhD, Carole Le Pogam, BSc, Didier Auboeuf, PhD, Pierre de la Grange, PhD, Annie Soulie, Anne Janin, MD, PhD, Maria-Elena Noguera, MD, Pascal Merlet, MD, Laure Sarda-Mantel, MD, PhD, Pierre Fenaux, MD, PhD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Andrea Tu, PhD, Phoebe Yang, PhD, Alice C. Fan, MD, Scott C. Kogan, MD, Irving L. Weissman, MD, Dean W. Felsher, MD, PhD, Marika Pla, PhD, Robert West, PhD, Christine Chomienne, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3308.
https://doi.org/10.1182/blood.V116.21.3308.3308
Published: 2010