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Journal Articles

In Systemic Light-Chain Amyloidosis Complete and Very Good Partial Responses Are Not Enough: Involved Free Light Chain (iFLC) Levels < 10mg/L Are Associated with Optimal Long-Term Survival

Amandeep Godara, MD, Denis Toskic, BS, Benjamin Rosenthal, BS, Cindy Varga, MD BSc, Adin Kugelmass, BSc, Ping Zhou, MD PhD, Teresa Fogaren, NP, Raymond L Comenzo, MD

Blood (2019) 134 (Supplement_1): 4369.

https://doi.org/10.1182/blood-2019-127004

Published: 2019

Journal Articles

B-Cell Maturation Antigen (BCMA) in Systemic Light-Chain Amyloidosis (AL): Association with Disease Activity and Its Modulation with Gamma-Secretase Inhibition

Amandeep Godara, MD, Ping Zhou, MD PhD, Benjamin Rosenthal, BS, Adin Kugelmass, BSc, Denis Toskic, BS, Teresa Fogaren, NP, Cindy Varga, MD BSc, Raymond L Comenzo, MD

Blood (2019) 134 (Supplement_1): 4409.

https://doi.org/10.1182/blood-2019-126988

Published: 2019

Journal Articles

Effective Lipidoid Nanoparticle Delivery In Vivo of siRNA Targeting Kappa Light Chain Production in a Murine Xenograft Model

Xun Ma, DMD, MSc, PhD, Ping Zhou, MD PhD, Adin Kugelmass, BSc, Denis Toskic, Melissa Warner, BS, Lisa X. Lee, MD, Teresa Fogaren, NP, Ming Wang, PhD, Yamin Li, Liu Yang, Qiaobing Xu, Raymond Comenzo

Blood (2018) 132 (Supplement 1): 3208.

https://doi.org/10.1182/blood-2018-99-112682

Published: 2018

Journal Articles

Senescent CD8+ T Cells in Myeloma Patients: Implications for Cellular Therapies

Lisa Xingguang Lee, MD, Denis Toskic, Xun Ma, DMD, MSc, PhD, Ping Zhou, MD PhD, Adin Kugelmass, BSc, Teresa Fogaren, NP, Raymond L Comenzo, MD

Blood (2018) 132 (Supplement 1): 5688.

https://doi.org/10.1182/blood-2018-99-118514

Published: 2018

Journal Articles

Identifying a Murine Xenograft Model Relevant to Light-Chain Specific Approaches to Human Ig Light-Chain Diseases

Adin Kugelmass, BSc, Ping Zhou, MD PhD, Xun Ma, DMD, MSc, PhD, Denis Toskic, Amandeep Godara, MD, Melissa Warner, BS, Lisa Xingguang Lee, MD, Teresa Fogaren, NP, Cindy Varga, MD BSc, Raymond L Comenzo, MD

Blood (2018) 132 (Supplement 1): 5611.

https://doi.org/10.1182/blood-2018-99-119381

Published: 2018

Journal Articles

Seeking AL Amyloidosis Very Early: The SAVE Trial — Identifying Clonal Lambda Light Chain Genes in Patients with MGUS or Smoldering Multiple Myeloma

Ping Zhou, MD PhD, Adin Kugelmass, BSc, Denis Toskic, Melissa Warner, BS, Lisa X. Lee, MD, Teresa Fogaren, NP, Cindy Varga, MD BSc, Raymond L Comenzo, MD

Blood (2018) 132 (Supplement 1): 1903.

https://doi.org/10.1182/blood-2018-99-112902

Published: 2018

Journal Articles

siRNA for the Ig Light Chain Constant Region Reduces Light Chain Production and Secretion By Human Plasma Cells and in a Murine Xenograft Model

Xun Ma, DDS, PhD, Ping Zhou, MD PhD, Monika Pilichowska, MD, Chakra P Chaulagain, MD FACP, Sandy Wong, MD, Raymond L. Comenzo, MD

Blood (2014) 124 (21): 5722.

https://doi.org/10.1182/blood.V124.21.5722.5722

Published: 2014

Journal Articles

Proteasome Activity Not M-Protein Production Influences Multiple Myeloma (MM) Responsiveness to Bortezomib (BZB): The Key Role of PSMB5 ,

Ping Zhou, MD, PhD, Xun Ma, Raymond L. Comenzo, MD

Blood (2011) 118 (21): 3491.

https://doi.org/10.1182/blood.V118.21.3491.3491

Published: 2011

Journal Articles

Proteasome Activity As a Biomarker in Multiple Myeloma (MM): In MM Cells Treated with Bortezomib (BTZ) or Epoxomicin (EPX) Caspase 3/7 Activation Is Inversely Related to Baseline β1 and β5 Activity

Ping Zhou, MD, PhD,, Xun Ma, Raymond L. Comenzo, MD

Blood (2011) 118 (21): 1431.

https://doi.org/10.1182/blood.V118.21.1431.1431

Published: 2011

Journal Articles

Cyclin D1 Overexpression In Clonal Plasma Cells In Systemic AL Amyloidosis Is Associated with Differential Expression of Protein Quality Control Genes and Bias In Clonal Germline IgV L donor Gene Use

Ping Zhou, MD, PhD, Lakshmanan K Iyer, PhD, Hani Hassoun, MD, James E. Hoffman, MD, Heather Landau, MD, Raymond L. Comenzo, MD

Blood (2010) 116 (21): 4043.

https://doi.org/10.1182/blood.V116.21.4043.4043

Published: 2010

Journal Articles

CD32B Expression Reflects Phenotypic and Functional Heterogeneity in Multiple Myeloma (MM)

Ping Zhou, MD, PhD, Adam M Boruchov, MD, James E. Hoffman, MD, Qianxing Mo, Adam Olshen, Evan Glasner, Ezio Bonvini, Scott Koenig, Ellen Drieghe, Martin Fleisher, PhD, Peter Maslak, MD, Hani Hassoun, MD, Adam D Cohen, MD, Heather Landau, MD, James W. Young, MD, Suresh C Jhanwar, PhD, Stephen D Nimer, MD, Raymond L Comenzo

Blood (2008) 112 (11): 842.

https://doi.org/10.1182/blood.V112.11.842.842

Published: 2008

Journal Articles

Mobilization of Blood Stem Cells with G-CSF in Systemic Light-Chain Amyloidosis: Dominant Organ Involvement Significantly Affects Stem Cell Collection.

Raymond Comenzo, MD, Hani Hassoun, MD, Lilian Reich, MD, Nancy Collins, PhD, Andre Nuta, Xiaoshe Chen, PhD, Ping Zhou, MD. PhD, Bradly Clark, MD, Julie Teruya-Feldstein, MD, Martin Fleisher, PhD, David Wuest, MD, Stephen D. Nimer, MD

Blood (2006) 108 (11): 3087.

https://doi.org/10.1182/blood.V108.11.3087.3087

Published: 2006

Journal Articles

Increased Calreticulin Expression in Clonal Plasma Cells Is Associated with Complete Response to Melphalan and Autologous Stem Cell Transplant in Systemic Light-Chain Amyloidosis.

Ping Zhou, MD, PhD, Adam B. Olshen, PhD, Julie Teruya-Feldstein, MD, Raymond Comenzo, MD

Blood (2006) 108 (11): 3096.

https://doi.org/10.1182/blood.V108.11.3096.3096

Published: 2006

Journal Articles

Plasma Cell Gene-Expression Profiles in Patients with Systemic AL Amyloidosis: Responses to Melphalan and Stem Cell Transplant Are Associated with Differential Expression of Genes Involved in Translation, Protein Degradation and Detoxification.

Raymond L. Comenzo, MD, Ping Zhou, MD, PhD, Limin Wang, PhD, Stephen D. Nimer, MD, Adam B. Olshen, PhD

Blood (2005) 106 (11): 3405.

https://doi.org/10.1182/blood.V106.11.3405.3405

Published: 2005

Journal Articles

Adjuvant Dexamethasone (D) ± Thalidomide (T) Improves Hematologic and Organ Responses after Risk-Adapted High-Dose Melphalan with Autologous Stem Cell Transplant (SCT) for Patients with Systemic AL Amyloidosis (AL).

Adam D. Cohen, MD, Ping Zhou, MD, PhD, Lillian Reich, MD, Hani Hassoun, MD, Julie Teruya-Feldstein, MD, Daniel A. Filippa, MD, Martin Fleisher, PhD, Stephen D. Nimer, MD, Raymond L. Comenzo, MD

Blood (2005) 106 (11): 1163.

https://doi.org/10.1182/blood.V106.11.1163.1163

Published: 2005

Journal Articles

Seeking Diagnostic Confidence in Typing Amyloidosis: Prospective Results with an Algorithm To Minimize Misdiagnosis of Immunoglobulin Light-Chain (AL) Amyloidosis.

Raymond L. Comenzo, MD, Ping Zhou, MD, PhD, Limin Wang, PhD, Bradly D. Clark, MD, Martin Fleisher, PhD, Julie Teruya-Feldstein, MD

Blood (2005) 106 (11): 5099.

https://doi.org/10.1182/blood.V106.11.5099.5099

Published: 2005

Journal Articles

The Abdominal Fat Pad Aspirate for Diagnosing Amyloidosis Is a Useful Tool.

Bradly D. Clark, MD, Oscar Lin, MD, PhD, Andre Moreira, MD, Julie Teruya-Feldstein, MD, Cristina R. Antonescu, MD, Hani Hassoun, MD, Ping Zhou, MD, PhD, Martin Fleisher, PhD, Raymond L. Comenzo, MD

Blood (2005) 106 (11): 5107.

https://doi.org/10.1182/blood.V106.11.5107.5107

Published: 2005

Journal Articles

Risk-Adapted Dosing of Melphalan for Systemic AL Amyloidosis (AL) Lowers Treatment-Related Mortality: Early Death but Not Post-3 Month Survival Is Linked to Cardiac Involvement.

Raymond L. Comenzo, MD, Ping Zhou, MD, PhD, Hani Hassoun, MD, Tarun Kewalramani, MD, Virginia Klimek, MD, Adam D. Cohen, MD, Susane K. Ferrand, MD, Madhav Dhodapkar, MD, Julie Teruya-Feldstein, MD, Martin Fleisher, PhD, Stephen D. Nimer, MD

Blood (2005) 106 (11): 1156.

https://doi.org/10.1182/blood.V106.11.1156.1156

Published: 2005

Journal Articles

Frequency of Molecular and PET/CT Complete Remissions in Patients with Multiple Myeloma after Autologous Followed by Reduced-Intensity Allogeneic Stem Cell Transplants.

Ping Zhou, MD, PhD, Hugo Castro-Malaspina, MD, Esperanza B. Papadopoulos, MD, James W. Young, MD, Kenneth Miller, MD, Neeta Pandit-Taskar, MD, Daniel A. Filippa, MD, Martin Fleisher, PhD, Raymond L. Comenzo, MD

Blood (2004) 104 (11): 5113.

https://doi.org/10.1182/blood.V104.11.5113.5113

Published: 2004

NARROW

In Systemic Light-Chain Amyloidosis Complete and Very Good Partial Responses Are Not Enough: Involved Free Light Chain (iFLC) Levels < 10mg/L Are Associated with Optimal Long-Term Survival

B-Cell Maturation Antigen (BCMA) in Systemic Light-Chain Amyloidosis (AL): Association with Disease Activity and Its Modulation with Gamma-Secretase Inhibition

Effective Lipidoid Nanoparticle Delivery In Vivo of siRNA Targeting Kappa Light Chain Production in a Murine Xenograft Model

Senescent CD8+ T Cells in Myeloma Patients: Implications for Cellular Therapies

Identifying a Murine Xenograft Model Relevant to Light-Chain Specific Approaches to Human Ig Light-Chain Diseases

Seeking AL Amyloidosis Very Early: The SAVE Trial — Identifying Clonal Lambda Light Chain Genes in Patients with MGUS or Smoldering Multiple Myeloma

siRNA for the Ig Light Chain Constant Region Reduces Light Chain Production and Secretion By Human Plasma Cells and in a Murine Xenograft Model

Proteasome Activity Not M-Protein Production Influences Multiple Myeloma (MM) Responsiveness to Bortezomib (BZB): The Key Role of PSMB5 ,

Proteasome Activity As a Biomarker in Multiple Myeloma (MM): In MM Cells Treated with Bortezomib (BTZ) or Epoxomicin (EPX) Caspase 3/7 Activation Is Inversely Related to Baseline β1 and β5 Activity

Cyclin D1 Overexpression In Clonal Plasma Cells In Systemic AL Amyloidosis Is Associated with Differential Expression of Protein Quality Control Genes and Bias In Clonal Germline IgV L donor Gene Use

CD32B Expression Reflects Phenotypic and Functional Heterogeneity in Multiple Myeloma (MM)

Mobilization of Blood Stem Cells with G-CSF in Systemic Light-Chain Amyloidosis: Dominant Organ Involvement Significantly Affects Stem Cell Collection.

Increased Calreticulin Expression in Clonal Plasma Cells Is Associated with Complete Response to Melphalan and Autologous Stem Cell Transplant in Systemic Light-Chain Amyloidosis.

Plasma Cell Gene-Expression Profiles in Patients with Systemic AL Amyloidosis: Responses to Melphalan and Stem Cell Transplant Are Associated with Differential Expression of Genes Involved in Translation, Protein Degradation and Detoxification.

Adjuvant Dexamethasone (D) ± Thalidomide (T) Improves Hematologic and Organ Responses after Risk-Adapted High-Dose Melphalan with Autologous Stem Cell Transplant (SCT) for Patients with Systemic AL Amyloidosis (AL).

Seeking Diagnostic Confidence in Typing Amyloidosis: Prospective Results with an Algorithm To Minimize Misdiagnosis of Immunoglobulin Light-Chain (AL) Amyloidosis.

The Abdominal Fat Pad Aspirate for Diagnosing Amyloidosis Is a Useful Tool.

Risk-Adapted Dosing of Melphalan for Systemic AL Amyloidosis (AL) Lowers Treatment-Related Mortality: Early Death but Not Post-3 Month Survival Is Linked to Cardiac Involvement.

Frequency of Molecular and PET/CT Complete Remissions in Patients with Multiple Myeloma after Autologous Followed by Reduced-Intensity Allogeneic Stem Cell Transplants.

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American Society of Hematology

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American Society of Hematology

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