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Polina Matre, PhD
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Journal Articles

ONC201 Induces p53-Independent Apoptosis and Cell Cycle Arrest in Hematological Malignancies and Leukemic Stem/Progenitor Cells By Inducing ER Stress and mTOR Inhibition

Jo Ishizawa, MD PhD, Kensuke Kojima, MD PhD, Dhruv Chachad, MS, Peter P. Ruvolo, PhD, Vivian R Ruvolo, MA, Rodrigo Jacamo, PhD, Archana Dilip, MS, Hong Mu, MD PhD, Zhihong Zeng, MD, Polina Matre, PhD, Joshua E. Allen, PhD, Sattva S Neelapu, MD, Timothy J. McDonnell, MD PhD, Roberto N. Miranda, MD, Larry W. Kwak, MD PhD, Hagop M. Kantarjian, MD, Marina Konopleva, MD PhD, R Eric Davis, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3122.
https://doi.org/10.1182/blood.V124.21.3122.3122
Published: 2014
Journal Articles

Efficacy of Novel Glutaminase Inhibitor CB-839 in Acute Myeloid Leukemia

Polina Matre, PhD, Maryam Shariati, Juliana Velez, Yuan Qi, Sergej Konoplev, MD PhD, Xiaoping Su, PhD, Courtney D. DiNardo, MD, Naval Daver, MD, Ravi Majeti, MD PhD, Michael Andreeff, MD PhD, Steven M. Chan, MD PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3763.
https://doi.org/10.1182/blood.V124.21.3763.3763
Published: 2014
Journal Articles

Novel Nanomolar Potency Mitochondrial Complex I Inhibitor Iacs-1131 Selectively Kills Oxphos-Dependent AML Cells

Polina Matre, PhD, Marina Protopopova, Ningping Feng, Jason Gay, Jennifer Greer, Juliana Velez, Hong Mu, MD PhD, Alessia Lodi, Surendar Tadi, Shannon Sweeney, Michael Andreeff, MD PhD, Stefano Tiziani, M. Emilia DiFrancesco, Joseph Marszalek, Marina Konopleva, MD PhD
Journal: Blood
Blood (2014) 124 (21): 622.
https://doi.org/10.1182/blood.V124.21.622.622
Published: 2014
Journal Articles

Unraveling The Molecular and Metabolic Basis For Glutamine Addiction In Leukemias

Polina Matre, PhD, Ismael Samudio, PhD, Rodrigo Jacamo, PhD, Ying Wang, Jing Wang, R Eric Davis, Xiaohua Su, Sonja Schindela, Rachel Newman, Jianhua Hu, Torsten Haferlach, MD, Michael Andreeff, MD, PhD, Elsa R. Flores, Aaron Schimmer, PhD, MD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 606.
https://doi.org/10.1182/blood.V122.21.606.606
Published: 2013