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Journal Articles

Co-Targeting BET Bromodomain Proteins and Aberrant Signaling in AML

Benjamin J. Huang, MD, Xinyue Wang, BA, Max Harris, BA, Anica Wandler, PhD, Eugene Hwang, BA, Michael R. Burgess, MD PhD, Qing Li, MD PhD, Paul Severson, PhD, Ben Powell, PhD, Edward A. Kolb, MD, Soheil Meshinchi, MDPhD, Barry S Taylor, PhD, Gideon Bollag, PhD, Kevin M. Shannon, MD

Blood (2020) 136 (Supplement 1): 5–6.

https://doi.org/10.1182/blood-2020-142921

Published: 2020

Journal Articles

Chidamide Combined with Decitabine Synergistically Induce Apoptosis of Acute Myeloid Leukemia By up-Regulating Perp gene In Vivo and in Vitro

Qing Li, MD, Yunfan Yang, MD, Yu Wu, MD

Blood (2019) 134 (Supplement_1): 536.

https://doi.org/10.1182/blood-2019-123876

Published: 2019

Journal Articles

Caudal Type Homeobox 2 Is Required for Leukemogenesis but Not for Normal Hematopoieisis

Morgan A Jones, MD PhD BS, MS, Meiling Zhao, MS, Lu Liu, PhD, Ying Feng, PhD, Adam Ross, Eric R Fearon, MD PhD, Qing Li, MD PhD

Blood (2019) 134 (Supplement_1): 3770.

https://doi.org/10.1182/blood-2019-130985

Published: 2019

Journal Articles

Mutation of Murine Rpl5 reveals a New Model for Diamond Blackfan Anemia Characterized By Defective Erythropoiesis

Philippe Lemay, PhD, Morgan A Jones, MD PhD BS, MS, Fatma Mohamed, Marie-Claude Guyot, Alexander Ludlow, Qing Li, MD, James Douglas Engel, PhD, Renny Franceschi, PhD, Thomas L. Rothstein, MD PhD, Vesa Kaartinen, PhD, Zoha Kibar, PhD, Sharon A Singh, MD

Blood (2019) 134 (Supplement_1): 2495.

https://doi.org/10.1182/blood-2019-131526

Published: 2019

Journal Articles

Integrative Next Generation Sequencing of Myeloproliferative Neoplasms and Correlation of Genetic Variations to Disease Severity

Malathi Kandarpa, PhD, Kristen Pettit, MD, Yi-Mi Wu, PhD, Qing Li, MD, Robert Lonigro, Dan Robinson, PhD, Luke F. Peterson, PhD, Philip S Boonstra, PhD, Arul Chinnaiyan, MD, Moshe Talpaz, MD

Blood (2018) 132 (Supplement 1): 4324.

https://doi.org/10.1182/blood-2018-99-113418

Published: 2018

Journal Articles

RAS-MPAK Pathway Signaling in Health and Disease

Qing Li, MD PhD

Blood (2018) 132 (Supplement 1): SCI-40.

https://doi.org/10.1182/blood-2018-99-109378

Published: 2018

Journal Articles

Effect of Chidamide, a Novel HDAC Inhibitor, on AML Cell Lines and Patients

Yu Wu, MD PhD, Qing Li, MD, Jingcao Huang, MD, Yuhuan Zheng, PhD, Fangfang Wang

Blood (2017) 130 (Supplement 1): 5056.

https://doi.org/10.1182/blood.V130.Suppl_1.5056.5056

Published: 2017

Journal Articles

N-RasG12D-Mediated Dysregulation of IRE1alpha-Xbp1s Signaling Promotes Pre-Leukemic Hematopoietic Stem Cell Expansion

Lu Liu, PhD, Meiling Zhao, MS, Kevin B Yang, Xi Jin, PhD, Gina Ney, MD PhD, Juan Del Valle, BS, PhD, Takao Iwawaki, PhD, Qing Li, MD PhD

Blood (2016) 128 (22): 567.

https://doi.org/10.1182/blood.V128.22.567.567

Published: 2016

Journal Articles

Hyperactive Nras and Dose Reduction of Tet2 Collaborate to Dys-Regulate Hematopoietic Stem Cells and Promote Leukemogenesis

Xi Jin, PhD, Tingting Qin, PhD, Nathanael G Bailey, MD, Meiling Zhao, MS, Kevin B Yang, Victor Ng, MS, Lu Liu, PhD, Rosemary Coolon, MS, Gina Ney, MD PhD, Maria E Figueroa, MD, Qing Li, MD PhD

Blood (2016) 128 (22): 1204.

https://doi.org/10.1182/blood.V128.22.1204.1204

Published: 2016

Journal Articles

Targeting the Creatine Kinase Pathway in EVI1-Positive Acute Myeloid Leukemia

Alexandre Puissant, PhD, Nina Fenouille, PhD, Christopher F. Bassil, BA, Issam Ben-Sahra, PhD, Lina Benajiba, Gabriela Alexe, PhD, Azucena Ramos, Yana Pikman, MD, Michael R. Burgess, MD PhD, Qing Li, MD PhD, Frederic Luciano, PhD, Patrick Auberger, PhD, Ilene Galinsky, MSN, ANPc, Daniel J. DeAngelo, MD PhD, Richard M. Stone, MD, Archibald S. Perkins, MD PhD, Kevin Shannon, MD, Michael T. Hemann, PhD, Kimberly Stegmaier, MD

Blood (2016) 128 (22): 523.

https://doi.org/10.1182/blood.V128.22.523.523

Published: 2016

Journal Articles

Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression

Blood (2016) 128 (22): 753.

https://doi.org/10.1182/blood.V128.22.753.753

Published: 2016

Journal Articles

Oncogenic Nras Grants Apoptosis Resistance to Hematopoietic Stem Cells

Kevin B Yang, Victor Ng, MS, Gina Ney, MD PhD, Lu Liu, PhD, Xi Jin, PhD, Qing Li, MD PhD

Blood (2015) 126 (23): 2451.

https://doi.org/10.1182/blood.V126.23.2451.2451

Published: 2015

Journal Articles

High Risk Older AML Patients May be Benefited from the Treatment of Decitabine Combined Wih CAG Regimens

Xia Xiao, MD, Mingfeng Zhao, MDPhD, Qi Deng, MD, Qing Li, MD, Juan Mu, MD, Li Geng, MD, Yuming Li, MD

Blood (2014) 124 (21): 4953.

https://doi.org/10.1182/blood.V124.21.4953.4953

Published: 2014

Journal Articles

The Bone Marrow-Derived Mesenchymal Cells Were Injured By Iron Overload through Catalyzing the Production of Reactive Oxidative Stress in Mice

Yuchen Zhang, MD, Mingfeng Zhao, MDPhD, Deguan Li, PhD, Xiaoli Cao, MD, Jie Chen, MD, Juan Mu, MD, Qing Li, MD, Xia Xiao, MD, Xiao Chai, MD, Aimin Meng, PhD

Blood (2014) 124 (21): 4373.

https://doi.org/10.1182/blood.V124.21.4373.4373

Published: 2014

Journal Articles

Preclinical Efficacy of MEK Inhibition in Nras Mutant Acute Myeloid Leukemia

Michael R. Burgess, MD PhD, Eugene Hwang, BA, Ari J Firestone, PhD, Tannie Huang, MD, Jin Xu, PhD, Johannes Zuber, MD, Natacha Bohin, BS, Tiffany Wen, BS, Scott C. Kogan, MD, Kevin M. Haigis, PhD, Scott W. Lowe, PhD, Kevin Shannon, MD, Qing Li, MD PhD

Blood (2014) 124 (21): 3753.

https://doi.org/10.1182/blood.V124.21.3753.3753

Published: 2014

Journal Articles

ROS-Mediated Iron Overload Injures The Hematopoiesis Of Bone Marrow By Damaging Hematopoietic Stem/Progenitor Cells In Mice

Xiao Chai, MD, Deguan Li, PhD, Mingfeng Zhao, MD&PhD, Wenyi Lu, MD, Juan Mu, MD, Xia Xiao, MD, Yuchen Zhang, MD, Qing Li, MD, Juanxia Meng, MD, Tao Sui, MD&PhD, Aimin Meng, PhD

Blood (2013) 122 (21): 962.

https://doi.org/10.1182/blood.V122.21.962.962

Published: 2013

Journal Articles

IL-21 Enhances Anti-Leukemia Effect By Acting On Both CD3+CD56+ CIK Cells and Regulatory T Cells Derived From Umbilical Cord Blood In Vitro

Juanxia Meng, MD, Mingfeng Zhao, MD&PhD, Xiao Chai, MD, Xia Xiao, MD, Juan Mu, MD, Qing Li, MD, Qi Deng, MD, Yuming Li, MD

Blood (2013) 122 (21): 1051.

https://doi.org/10.1182/blood.V122.21.1051.1051

Published: 2013

Journal Articles

Leukemic Stem Cells Immunophenotype Expression in Patients with Acute Leukemia Has a Poor Prognosis.

Mingfeng Zhao, MD&PhD, Haibo Zhu, MD, Sajin Rajbhandary, MD, Xia Xiao, MD, Qi Deng, MD, Juan Mu, MD, Qing Li, MD, Yuming Li, MD

Blood (2012) 120 (21): 2504.

https://doi.org/10.1182/blood.V120.21.2504.2504

Published: 2012

Journal Articles

Kras G12D Expression in Hematopoietic Stem/Progenitor Cells Initiates T Cell Acute Lymphoblastic Leukemia/Lymphoma.

Monique Dail, PhD, Qing Li, MD, PhD, Jennifer Lauchle, MD, Andrew McDaniel, Doris Kim, Keiko Akagi, PhD, Linda Wolff, PhD, Nancy Jenkins, PhD, Neil Copeland, PhD, Kevin Shannon, MD

Blood (2007) 110 (11): 153.

https://doi.org/10.1182/blood.V110.11.153.153

Published: 2007

Journal Articles

Expressing N-Ras G12D from the Endogenous Promoter Induces Myeloproliferative Disease (MPD) and Cooperates with Retroviral Insertional Mutagenesis (RIM) To Generate Acute Myeloid Leukemia (AML).

Qing Li, MD, PhD, Kevin Haigis, Ph.D., Andrew McDaniel, B.S., Benjamin Huang, B.S., Michelle Miller, Angell Shieh, B.S., Scott Kogan, M.D., Lynda Wolff, Ph.D., Tyler Jacks, Ph.D., Kevin Shannon, M.D.

Blood (2007) 110 (11): 1616.

https://doi.org/10.1182/blood.V110.11.1616.1616

Published: 2007

NARROW

Co-Targeting BET Bromodomain Proteins and Aberrant Signaling in AML

Chidamide Combined with Decitabine Synergistically Induce Apoptosis of Acute Myeloid Leukemia By up-Regulating Perp gene In Vivo and in Vitro

Caudal Type Homeobox 2 Is Required for Leukemogenesis but Not for Normal Hematopoieisis

Mutation of Murine Rpl5 reveals a New Model for Diamond Blackfan Anemia Characterized By Defective Erythropoiesis

Integrative Next Generation Sequencing of Myeloproliferative Neoplasms and Correlation of Genetic Variations to Disease Severity

RAS-MPAK Pathway Signaling in Health and Disease

Effect of Chidamide, a Novel HDAC Inhibitor, on AML Cell Lines and Patients

N-RasG12D-Mediated Dysregulation of IRE1alpha-Xbp1s Signaling Promotes Pre-Leukemic Hematopoietic Stem Cell Expansion

Hyperactive Nras and Dose Reduction of Tet2 Collaborate to Dys-Regulate Hematopoietic Stem Cells and Promote Leukemogenesis

Targeting the Creatine Kinase Pathway in EVI1-Positive Acute Myeloid Leukemia

Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression

Oncogenic Nras Grants Apoptosis Resistance to Hematopoietic Stem Cells

High Risk Older AML Patients May be Benefited from the Treatment of Decitabine Combined Wih CAG Regimens

The Bone Marrow-Derived Mesenchymal Cells Were Injured By Iron Overload through Catalyzing the Production of Reactive Oxidative Stress in Mice

Preclinical Efficacy of MEK Inhibition in Nras Mutant Acute Myeloid Leukemia

ROS-Mediated Iron Overload Injures The Hematopoiesis Of Bone Marrow By Damaging Hematopoietic Stem/Progenitor Cells In Mice

IL-21 Enhances Anti-Leukemia Effect By Acting On Both CD3+CD56+ CIK Cells and Regulatory T Cells Derived From Umbilical Cord Blood In Vitro

Leukemic Stem Cells Immunophenotype Expression in Patients with Acute Leukemia Has a Poor Prognosis.

Kras G12D Expression in Hematopoietic Stem/Progenitor Cells Initiates T Cell Acute Lymphoblastic Leukemia/Lymphoma.

Expressing N-Ras G12D from the Endogenous Promoter Induces Myeloproliferative Disease (MPD) and Cooperates with Retroviral Insertional Mutagenesis (RIM) To Generate Acute Myeloid Leukemia (AML).

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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