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Journal Articles

Hyper-Active Non-Homologous End Joining Selects for Synthetic Lethality Resistant and Pathological Hematopoietic Stem Cells

Wei Du, MD, PhD, Surya Amarachintha, Wilson Andrew, Qishen Pang, PhD

Blood (2015) 126 (23): 5400.

https://doi.org/10.1182/blood.V126.23.5400.5400

Published: 2015

Journal Articles

KIT Blockade Is Sufficient to Sustain Donor Hematopoietic Stem Cell Engraftment in Fanconi Anemia Mice

Shanmuganathan Chandrakasan, MD, Rajeswari Jayavaradhan, MS, Ernst John, Archana Shrestha, MS, Phillip Dexheimer, MS, Michael B. Jordan, MD, Qishen Pang, PhD, Bruce J. Aronow, PhD, Punam Malik, MD

Blood (2015) 126 (23): 1206.

https://doi.org/10.1182/blood.V126.23.1206.1206

Published: 2015

Journal Articles

Differential Response of Fanconi Anemia Hematopoietic Stem and Progenitor Cells to Oxidative and Oncogenic Stresses

Wei Du, MD PhD, Surya Amarachintha, PhD, Erden Ozlem, Qishen Pang, PhD

Blood (2014) 124 (21): 3593.

https://doi.org/10.1182/blood.V124.21.3593.3593

Published: 2014

Journal Articles

Enhanced Notch Signaling Skews Hematopoietic Stem Cell Differentiation in Fanconi Anemia Murine Models

Wei Du, MD, PhD, Jared Sipple, Jonathan Schick, Qishen Pang, PhD

Blood (2012) 120 (21): 1191.

https://doi.org/10.1182/blood.V120.21.1191.1191

Published: 2012

Journal Articles

Targeting mTOR by a New Generation of Kinase Inhibitors Sensitizes Leukemia Cells for Chemotherapy Via Suppressing FANCD2 Expression

Jie Li, Fukun Guo, Jared Sipple, Sara Kozma, George Thomas, Yi Zheng, PhD, Qishen Pang, PhD

Blood (2011) 118 (21): 1514.

https://doi.org/10.1182/blood.V118.21.1514.1514

Published: 2011

Journal Articles

mTOR Regulates DNA Damage Response of Hematopoietic Stem and Progenitor Cells Through Modulation of Fanconi Anemia Core Complex

Fukun Guo, Jie Li, PhD, Wei Du, MD, PhD, Shuangmin Zhang, Wei Liu, M.D., M.S., George Thomas, Sara Kozma, Qishen Pang, PhD, Yi Zheng, PhD

Blood (2011) 118 (21): 864.

https://doi.org/10.1182/blood.V118.21.864.864

Published: 2011

Journal Articles

Selective Damage to Antioxidant Gene Promoters in FA Cells

Wei Du, MD, PhD, Reena Rani, Jared Sipple, Jonathan Schick, Qishen Pang, PhD

Blood (2011) 118 (21): 2413.

https://doi.org/10.1182/blood.V118.21.2413.2413

Published: 2011

Journal Articles

Increased Oxidative Stress and Genomic Instability in Peripheral Blood and Bone Marrow of Individuals with Fanconi Anemia,

Kasiani C. Myers, MD, Gretchen A Radloff, Melissa Scholz, Lisa Campbell, Jennifer E Hauser, Parinda A Mehta, MD, Robin Mueller, Lisa Vormohr, Richard E. Harris, MD, Qishen Pang, PhD, Stella M. Davies, MBBS, PhD

Blood (2011) 118 (21): 3425.

https://doi.org/10.1182/blood.V118.21.3425.3425

Published: 2011

Journal Articles

Rational Targeting of the Signaling GTPase Cdc42 Establishes a Non-Myeloid Ablative Regimen for Hematopoietic Stem Cell Engraftment In Mouse Models

Wei Liu, M.D., M.S., Wei Du, MD, PhD, James F Johnson, BS, Qishen Pang, PhD, Yi Zheng, Ph.D.

Blood (2010) 116 (21): 73.

https://doi.org/10.1182/blood.V116.21.73.73

Published: 2010

Journal Articles

Loss of Foxo3a In FA Mice Leads to Hematopoietic Stem Cell Exhaustion That Can Be Attenuated by Natural Anti-Oxidant Quercetin.

Jie Li, Jared Sipple, Qishen Pang, PhD

Blood (2010) 116 (21): 1166.

https://doi.org/10.1182/blood.V116.21.1166.1166

Published: 2010

Journal Articles

Overexpression of IL-3R alpha on CD34+CD38- Stem Cells Defines Leukemia-Initiating Cells In FA AML.

Wei Du, MD, PhD, Jared Sipple, Qishen Pang, PhD

Blood (2010) 116 (21): 1667.

https://doi.org/10.1182/blood.V116.21.1667.1667

Published: 2010

Journal Articles

Oxidative-Stress Specific Interaction Between FANCD2 and FOXO3a.

Jie Li, PhD, Suzette Maynard, Paul R. Andreassen, PhD, Qishen Pang, PhD

Blood (2009) 114 (22): 1089.

https://doi.org/10.1182/blood.V114.22.1089.1089

Published: 2009

Journal Articles

A Cytoplasmic FANCA-FANCC Complex Interacts and Stabilizes the Leukemic NPMc Protein.

Wei Du, PhD., M.D., Suzette Maynard, Jared Sipple, Jie Li, PhD, Qishen Pang, PhD

Blood (2009) 114 (22): 3098.

https://doi.org/10.1182/blood.V114.22.3098.3098

Published: 2009

Journal Articles

Cdk1-Dependent Phosphorylation ofNPM Overrides G 2 /M Checkpoint and Increases Leukemic Blasts in Mice

Wei Du, M.D., PhD., Yun Zhou, PhD, Suzette Pike, MS, Qishen Pang, PhD

Blood (2008) 112 (11): 1322.

https://doi.org/10.1182/blood.V112.11.1322.1322

Published: 2008

Journal Articles

Defective Adhesion, Migration and Homing Are Associated with Altered Rho GTPase Activity in Cells from Fanconi Anemia Patients.

Xiaoling Zhang, MD, Xun Shang, PhD, Lei Wang, PhD, Fukun Guo, PhD, Yi Zheng, PhD, Qishen Pang, PhD

Blood (2006) 108 (11): 350.

https://doi.org/10.1182/blood.V108.11.350.350

Published: 2006

Journal Articles

Tumor Necrosis Factor-Mediated Inflammation Exacerbates Genomic Instability and Promotes Leukemia Development.

June Li, PhD, MD, Daniel P. Sejas, Ms, Xiaoling Zhang, MD, Reena Rani, PhD, Qishen Pang, PhD

Blood (2006) 108 (11): 4265.

https://doi.org/10.1182/blood.V108.11.4265.4265

Published: 2006

Journal Articles

Reoxygenation Induces Premature Senescence of FA Hematopoietic Progenitor/Stem Cells through a Pathway Involving ATM, P53, and P21 CIP1/WAF1 .

Xiaoling Zhang, MD, June Li, PhD, Daniel P. Sejas, MS, Qishen Pang, PhD

Blood (2004) 104 (11): 34.

https://doi.org/10.1182/blood.V104.11.34.34

Published: 2004

Journal Articles

Nucleophosmin Protects Hematopoietic Cells from Stress-Induced Apoptosis through Inhibition of P53.

Qishen Pang, PhD, June Li, PhD, Xiaoling Zhang, MD, Daniel P. Sejas, MS, Grover C. Bagby, MD

Blood (2004) 104 (11): 2558.

https://doi.org/10.1182/blood.V104.11.2558.2558

Published: 2004

NARROW

Hyper-Active Non-Homologous End Joining Selects for Synthetic Lethality Resistant and Pathological Hematopoietic Stem Cells

KIT Blockade Is Sufficient to Sustain Donor Hematopoietic Stem Cell Engraftment in Fanconi Anemia Mice

Differential Response of Fanconi Anemia Hematopoietic Stem and Progenitor Cells to Oxidative and Oncogenic Stresses

Enhanced Notch Signaling Skews Hematopoietic Stem Cell Differentiation in Fanconi Anemia Murine Models

Targeting mTOR by a New Generation of Kinase Inhibitors Sensitizes Leukemia Cells for Chemotherapy Via Suppressing FANCD2 Expression

mTOR Regulates DNA Damage Response of Hematopoietic Stem and Progenitor Cells Through Modulation of Fanconi Anemia Core Complex

Selective Damage to Antioxidant Gene Promoters in FA Cells

Increased Oxidative Stress and Genomic Instability in Peripheral Blood and Bone Marrow of Individuals with Fanconi Anemia,

Rational Targeting of the Signaling GTPase Cdc42 Establishes a Non-Myeloid Ablative Regimen for Hematopoietic Stem Cell Engraftment In Mouse Models

Loss of Foxo3a In FA Mice Leads to Hematopoietic Stem Cell Exhaustion That Can Be Attenuated by Natural Anti-Oxidant Quercetin.

Overexpression of IL-3R alpha on CD34+CD38- Stem Cells Defines Leukemia-Initiating Cells In FA AML.

Oxidative-Stress Specific Interaction Between FANCD2 and FOXO3a.

A Cytoplasmic FANCA-FANCC Complex Interacts and Stabilizes the Leukemic NPMc Protein.

Cdk1-Dependent Phosphorylation ofNPM Overrides G 2 /M Checkpoint and Increases Leukemic Blasts in Mice

Defective Adhesion, Migration and Homing Are Associated with Altered Rho GTPase Activity in Cells from Fanconi Anemia Patients.

Tumor Necrosis Factor-Mediated Inflammation Exacerbates Genomic Instability and Promotes Leukemia Development.

Reoxygenation Induces Premature Senescence of FA Hematopoietic Progenitor/Stem Cells through a Pathway Involving ATM, P53, and P21 CIP1/WAF1 .

Nucleophosmin Protects Hematopoietic Cells from Stress-Induced Apoptosis through Inhibition of P53.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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