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Ranjeet Kumar Sinha, PhD
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Journal Articles

Novel R41Q- and R46Q-PAR1-Modified Mice Enable Proof-of-Concept Studies for In Vivo Protective Mechanisms of Action for Activated Protein C (APC) in Sepsis and Stroke

Ranjeet Kumar Sinha, PhD MSc, Yaoming Wang, PhD, Zhen Zhao, PhD, Jose A. Fernandez, MD PhD, Naveen Gupta, Xiao Xu, MSc, Greg Martin, MSc, Sergey Kupriyanov, PhD MSc, Laurent O Mosnier, PhD, Berislav Zlokovic, PhD, John H. Griffin, PhD
Journal: Blood
Blood (2016) 128 (22): 13.
https://doi.org/10.1182/blood.V128.22.13.13
Published: 2016
Journal Articles

Activated Protein C (APC) Therapy Ameliorates Chronic Graft Versus Host Disease By Cell Signaling Mechanisms That Require Cleavage at Arg46 in PAR1 on T Cells

Ranjeet Kumar Sinha, PhD MSc, Ryan P Flynn, PhD, Jose A. Fernandez, MD PhD, Xiao Xu, MSc, Greg Martin, MSc, Sergey Kupriyanov, PhD MSc, John H. Griffin, PhD, Bruce R. Blazar, MD
Journal: Blood
Blood (2016) 128 (22): 808.
https://doi.org/10.1182/blood.V128.22.808.808
Published: 2016
Journal Articles

Plasma Constitutive Serum Amyloid A4 Is Procoagulant and Is Elevated in Venous Thrombosis Patients

John H. Griffin, PhD, Jose A. Fernandez, MD PhD, Ranjeet Kumar Sinha, PhD MSc, Darlene J. Elias, MD, Hiroshi Deguchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3486.
https://doi.org/10.1182/blood.V126.23.3486.3486
Published: 2015
Journal Articles

Exome Genotyping Links Venous Thrombosis Risk with the Skeletal Muscle Myosin Gene Cluster and Leads to Discovery of New Family of Procoagulant Factors

Hiroshi Deguchi, MD PhD, Ranjeet Kumar Sinha, PhD MSc, Darlene J. Elias, MD, John H. Griffin, PhD
Journal: Blood
Blood (2015) 126 (23): 763.
https://doi.org/10.1182/blood.V126.23.763.763
Published: 2015
Journal Articles

Novel R41Q-PAR1-Modified Mice Enable Proof-of-Concept Studies for in Vivo Mechanisms of Action for Thrombin (IIa) and Activated Protein C (APC)

Ranjeet Kumar Sinha, PhD, Laurent Burnier, PhD, Naveen Gupta, MD, Xiao Xu, MS, Sergey Kupriyanov, PhD, Greg Martin, MS, Laurent O. Mosnier, PhD, John H. Griffin, PhD
Journal: Blood
Blood (2014) 124 (21): 99.
https://doi.org/10.1182/blood.V124.21.99.99
Published: 2014
Journal Articles

Activated Protein C Cytoprotective Signaling in Endothelial Cells Involves apoER2 and Disabled-1

Ranjeet Kumar Sinha, PhD, Xia Yang, PhD, Laurent O. Mosnier, PhD, John H. Griffin, PhD
Journal: Blood
Blood (2012) 120 (21): 1102.
https://doi.org/10.1182/blood.V120.21.1102.1102
Published: 2012
Journal Articles

Protection Against Vascular Leakage in Vivo by a Peptide Mimetic of the Novel Tethered Ligand Generated by Non-Canonical Cleavage of Protease Activated Receptor 1 by Activated Protein C

Laurent Burnier, PhD, Ranjeet Kumar Sinha, PhD, Eveline A. Bouwens, PhD, John H. Griffin, PhD, Laurent O. Mosnier, PhD
Journal: Blood
Blood (2012) 120 (21): 497.
https://doi.org/10.1182/blood.V120.21.497.497
Published: 2012