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Rimas Orentas, PhD
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Journal Articles

Phase 1 Study of on Site Manufactured Anti-CD19 CAR-T Cells: Responses in Subjects with Rapidly Progressive Refractory Lymphomas

Paolo F Caimi, MD, Jane Reese, Folashade Otegbeye, MBBChir,MPH, Dina Schneider, PhD, Kristen Bakalarz, CNP, Kirsten M Boughan, DO, Brenda Cooper, MD, Molly M Gallogly, MD PhD, Erin Galloway, RN BSN, Winfried Kruger, Andrew Worden, Michael Kadan, Filipa Blasco Lopes, Ashish Sharma, Ehsan Malek, MD, Leland Metheny, III, MD, Seema Patel, PharmD, Benjamin K. Tomlinson, MD, David Wald, MD PhD, Rafick-Pierre Sekaly, Rimas Orentas, PhD, Boro Dropulic, PhD, Marcos de Lima, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4074.
https://doi.org/10.1182/blood-2019-131300
Published: 2019
Journal Articles

Detailed Multi-Method Analysis of Bone Marrow from Pediatric Pre-B-ALL Patients Prior to CD19-CAR-T Therapy Subsequently Evidencing Overt CAR-T Resistance

Katherine Elizabeth Masih, BS, Rebecca Gardner, MD, Berkley Gryder, PhD, Abdelmaksoud Abdallah, BS, Justin Lack, PhD, Benjamin Stanton, PhD, Ashley Wilson, PhD, Sivasish Sindiri, MS, Young Song, PhD, Zachary Rae, BS, Michael Kelly, PhD, Wang Chaoyu, MS, Xinyu Wen, MS, Adam Cheuk, PhD, Jun Wei, PhD, Michael C. Jensen, MD, Javed Khan, MD, Rimas Orentas, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2744.
https://doi.org/10.1182/blood-2019-130796
Published: 2019
Journal Articles

Local Manufacture of CD19 CAR-T Cells Using an Automated Closed-System: Robust Manufacturing and High Clinical Efficacy with Low Toxicities

Olga Molostova, MD, Larisa Shelikhova, MD, Dina Schneider, PhD, Rimma Khismatullina, MD, Yakov Muzalevsky, Alexey Kazachenok, Liane Preussner, Georg Rauser, Julia Abugova, Elena Kurnikova, Dmitriy Pershin, Viktoria Zubachenko, Alexander Popov, MD PhD, Olga Illarionova, MD, Natalia Miakova, MD PhD, Dmitry Litvinov, MD, Galina Novichkova, MD PhD, Alexey A. Maschan, MD, Rimas Orentas, PhD, Boro Dropulic, PhD, Michael Maschan, MDMSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2625.
https://doi.org/10.1182/blood-2019-130370
Published: 2019
Journal Articles

Point-of-Care Manufacturing of CD20.19 Bi-Specific Chimeric Antigen Receptor T (CAR-T) Cells in a Standard Academic Cell Processing Facility for a Phase I Clinical Trial in Relapsed, Refractory NHL

Fenlu Zhu, PhD, Nirav N Shah, MD, Dina Schneider, PhD, Huiqing Xu, MD, Katherine Chaney, MS, Lawrence Luib, MS, Carolyn A. Keever-Taylor, DPhil, Boro Dropulic, PhD, Rimas Orentas, PhD, Parameswaran Hari, MBBS, MD, Bryon Johnson, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4553.
https://doi.org/10.1182/blood-2018-99-116566
Published: 2018
Journal Articles

Title Point-of-Care Production of CD19 CAR-T Cells in an Automated Closed-System: Report of First Clinical Experience

Olga Molostova, MD, Larisa Shelikhova, MD, Yakov Muzalevsky, Alexey Kazachenok, Dmitriy Pershin, Elena Kurnikova, Alexander Popov, MD PhD, Boro Dropulic, PhD, Dina Shneider, Rimas Orentas, PhD, Regina Alex, Mike Essl, Natalia Miakova, MD PhD, Dmitry Litvinov, MD PhD, Alexander Karachunskiy, MD PhD, Galina Novichkova, MD PhD, Alexey A. Maschan, MD, Michael Maschan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5202.
https://doi.org/10.1182/blood-2018-99-118282
Published: 2018
Journal Articles

A Phase 1 Study with Point-of-Care Manufacturing of Dual Targeted, Tandem Anti-CD19, Anti-CD20 Chimeric Antigen Receptor Modified T (CAR-T) Cells for Relapsed, Refractory, Non-Hodgkin Lymphoma

Nirav N Shah, MD, Fenlu Zhu, PhD, Carolyn Taylor, PhD, Dina Schneider, PhD, Winfried Krueger, Andrew Worden, Sharon Yim, Timothy S. Fenske, MD, Mehdi Hamadani, MD, Bryon Johnson, PhD, Boro Dropulic, PhD, Rimas Orentas, PhD, Parameswaran Hari, MBBS, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4193.
https://doi.org/10.1182/blood-2018-99-110194
Published: 2018
Journal Articles

Preclinical Development of a T-Cell ALL CAR Demonstrates That Differences in CAR Membrane Distribution May Impact Efficacy

Haneen Shalabi, DO, Haiying Qin, MS, Kelsey Wanhainen, BS, Jillian Smith, BS, Rimas Orentas, PhD, Nirali N Shah, MD, Shannon L Maude, MD PhD, Sarah K Tasian, MD, David T Teachey, MD, Javed Khan, MD, Terry J Fry, MD
Journal: Blood
Blood (2016) 128 (22): 4019.
https://doi.org/10.1182/blood.V128.22.4019.4019
Published: 2016
Journal Articles

CAR-T Cell Production Using the Clinimacs ® Prodigy System

Fenlu Zhu, PhD, Nirav N. Shah, MD MSHP, Huiqing Xu, MD, Dina Schneider, Rimas Orentas, PhD, Boro Dropulic, Parameswaran Hari, MD MRCP, MS, Carolyn A. Keever-Taylor, PhD
Journal: Blood
Blood (2016) 128 (22): 5724.
https://doi.org/10.1182/blood.V128.22.5724.5724
Published: 2016