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Journal Articles

The Unfolded Protein Response Causes Prothrombotic Transformation of Pancreatic Cancer Linking Tumor Progression with Cancer-Associated Thrombosis

Oluwatoyosi Muse, PhD, Rushad Patell, MD, Christian Peters, PhD, Sol Schulman, MD PhD, Emale Darzi, MS, Calvin Schuster, BA, Ling Huang, PhD, Shibani Mukherjee, PhD, Senthil Muthuswamy, PhD, Jeffrey I. Zwicker, MD, Robert C. Flaumenhaft, MD PhD

Blood (2019) 134 (Supplement_1): 632.

https://doi.org/10.1182/blood-2019-123544

Published: 2019

Journal Articles

VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex

Anish V. Sharda, MBBS, MPH, Joshua Harrison, BS, Adrian R. Wilkie, PhD, Chao Fang, PhD, Lourdes M. Mendez, MD PhD, Joseph E. Italiano, Jr., BS, PhD, Robert C. Flaumenhaft, MD PhD

Blood (2019) 134 (Supplement_1): 8.

https://doi.org/10.1182/blood-2019-127712

Published: 2019

Journal Articles

The Effects of Antiplatelet Agents on Endocytosis

Harvey G. Roweth, BSc,PhD, Michael Malloy, BS, Jodi A. Forward, BS, Julia Ceglowski, BA, Robert C. Flaumenhaft, MD PhD, Joseph E. Italiano, Jr., BS, PhD, Elisabeth Battinelli, MD PhD

Blood (2019) 134 (Supplement_1): 1058.

https://doi.org/10.1182/blood-2019-131912

Published: 2019

Journal Articles

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Jeffrey I. Zwicker, MD, Benjamin L. Schlechter, MD, Jack Davis Stopa, PhD, Howard A. Liebman, MD, Anita Aggarwal, PhDDO, Thomas Caughey, MD, Ken A. Bauer, MD, Nancy Kuemmerle, D.O., Ellice Y. Wong, MD, Ted Wun, MD, Marilyn Mclaughlin, MD, Maneka Puligandla, MS, Donna S Neuberg, ScD, Bruce Furie, MD, Robert C. Flaumenhaft, MD PhD

Blood (2018) 132 (Supplement 1): 985.

https://doi.org/10.1182/blood-2018-99-114946

Published: 2018

Journal Articles

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Chao Fang, PhD, Anish V. Sharda, MBBS, MPH, Lin Lin, PhD, Robert C. Flaumenhaft, MD PhD, Bruce Furie, MD

Blood (2017) 130 (Supplement 1): 442.

https://doi.org/10.1182/blood.V130.Suppl_1.442.442

Published: 2017

Journal Articles

Protein Disulfide Isomerase Negatively Regulates Platelet Function through Modulation of the Thromboxane A2 Receptor

Noppacharn Uaprasert, MB, BCH, Oskar Eriksson, MD PhD, Robert C. Flaumenhaft, MD PhD

Blood (2017) 130 (Supplement 1): 2297.

https://doi.org/10.1182/blood.V130.Suppl_1.2297.2297

Published: 2017

Journal Articles

Dysfunctional Endothelium Drives a Pre-DIC State in Endotoxemia

Karen E.P. De Ceunynck, PhD, Sarah J. Higgins, PhD, Sharjeel A. Chaudhry, B.S., Samir Parikh, MD PhD, Robert C. Flaumenhaft, MD PhD

Blood (2016) 128 (22): 3725.

https://doi.org/10.1182/blood.V128.22.3725.3725

Published: 2016

Journal Articles

A Chemical APC Mimetic Protects Endothelium from Thromboinflammatory Injury

Karen E.P. De Ceunynck, PhD, Christian G. Peters, PhD, Sharjeel A. Chaudhry, B.S., Abhishek Jain, PhD, Sarah J. Higgins, PhD, Omozuanvbo Aisiku, PhD, Jennifer Fitch-Tewfik, PhD, Christopher Dockendorff, PhD, Samir Parikh, MD PhD, Donald E. Ingber, PhD, Robert C. Flaumenhaft, MD PhD

Blood (2016) 128 (22): 3835.

https://doi.org/10.1182/blood.V128.22.3835.3835

Published: 2016

Journal Articles

Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure

Pavan K. Bendapudi, MD, Karen Deceunynck, PhD, Secil Koseoglu, PhD, Roelof Hendrik Bekendam, MD, Shauna D Mason, Jon Kenniston, Robert C. Flaumenhaft, MD PhD

Blood (2016) 128 (22): 258.

https://doi.org/10.1182/blood.V128.22.258.258

Published: 2016

Journal Articles

PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation

Jack D Stopa, PhD, Donna S. Neuberg, ScD, Maneka Puligandla, MS, Bruce Furie, MD, Robert C. Flaumenhaft, MD PhD, Jeffrey I. Zwicker, MD

Blood (2016) 128 (22): 2628.

https://doi.org/10.1182/blood.V128.22.2628.2628

Published: 2016

Journal Articles

Gα 13 Switch Region 2 Relieves Talin Autoinhibition to Activate Platelet αIIbβ3 Integrin

James Schiemer, BS, Andrew Bohm, PhD, Glenn Merrill-Skoloff, PhD, Robert C. Flaumenhaft, MD PhD, Guy Le Breton, PhD, Athar Chishti, PhD

Blood (2016) 128 (22): 712.

https://doi.org/10.1182/blood.V128.22.712.712

Published: 2016

Journal Articles

VAMP-7 Interacts With The Actin Cytoskeleton To Control Platelet Spreading and Mediate α-Granule Exocytosis During Thrombus Formation

Secil Koseoglu, PhD, Jennifer L Fitch-Tewfik, PhD, Christian G. Peters, PhD, Lydia Danglot, PhD, Thierry Galli, PhD, Robert C. Flaumenhaft, MD, PhD

Blood (2013) 122 (21): 1058.

https://doi.org/10.1182/blood.V122.21.1058.1058

Published: 2013

Journal Articles

The Functional Role of TLR9 in Human Platelets

Jonathan Noah Thon, Ph.D., Christian G. Peters, Ph.D., Rukhsana Aslam, Ph.D., Jesse Rowley, Ph.D., Andrew S. Weyrich, Ph.D., John W. Semple, PhD, Robert C. Flaumenhaft, MD, PhD, Joseph E. Italiano, Jr., PhD

Blood (2011) 118 (21): 366.

https://doi.org/10.1182/blood.V118.21.366.366

Published: 2011

Journal Articles

Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents

Reema Jasuja, Ph.D., Freda H. Passam, MD, PhD, Daniel R Kennedy, Ph.D., Sarah H Kim, Lotte van Hessem, Lin Lin, PhD, Sucharit S Joshi, MD, James R. Dilks, Bruce Furie, MD, Barbara C. Furie, PhD, Robert C. Flaumenhaft, MD, PhD

Blood (2011) 118 (21): 369.

https://doi.org/10.1182/blood.V118.21.369.369

Published: 2011

Journal Articles

Platelet Spreading Requires Exocytosis of a Subpopulation of α-Granules Expressing VAMP-7,

Robert C. Flaumenhaft, MD, PhD, Alan D. Michelson, MD, Christian G. Peters, Ph.D.

Blood (2011) 118 (21): 3248.

https://doi.org/10.1182/blood.V118.21.3248.3248

Published: 2011

Journal Articles

Dynamin-Related Protein-1 Controls Fusion Pore Dynamics During Platelet Granule Secretion and Thrombus Formation In Vivo

Robert C. Flaumenhaft, MD, PhD, Secil Koseoglu, James R. Dilks, Christian G. Peters, Ph.D., Nathalie A. Fadel, Reema Jasuja, Ph.D., Christy L. Haynes, Ph.D.

Blood (2011) 118 (21): 361.

https://doi.org/10.1182/blood.V118.21.361.361

Published: 2011

Journal Articles

An Allosteric Modulator of PAR1 Demonstrates Selective Inhibition of G Protein Coupling and Impairs Thrombus Formation In Vivo

Omozuanvbo R Aisiku, Chris Dockendorff, Suzanne F Gunnick, Daniel A. Smith, James R. Dilks, Louisa M. Dowal, Robert C. Flaumenhaft, MD, PhD

Blood (2011) 118 (21): 1138.

https://doi.org/10.1182/blood.V118.21.1138.1138

Published: 2011

NARROW

The Unfolded Protein Response Causes Prothrombotic Transformation of Pancreatic Cancer Linking Tumor Progression with Cancer-Associated Thrombosis

VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex

The Effects of Antiplatelet Agents on Endocytosis

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Protein Disulfide Isomerase Negatively Regulates Platelet Function through Modulation of the Thromboxane A2 Receptor

Dysfunctional Endothelium Drives a Pre-DIC State in Endotoxemia

A Chemical APC Mimetic Protects Endothelium from Thromboinflammatory Injury

Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure

PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation

Gα 13 Switch Region 2 Relieves Talin Autoinhibition to Activate Platelet αIIbβ3 Integrin

VAMP-7 Interacts With The Actin Cytoskeleton To Control Platelet Spreading and Mediate α-Granule Exocytosis During Thrombus Formation

The Functional Role of TLR9 in Human Platelets

Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents

Platelet Spreading Requires Exocytosis of a Subpopulation of α-Granules Expressing VAMP-7,

Dynamin-Related Protein-1 Controls Fusion Pore Dynamics During Platelet Granule Secretion and Thrombus Formation In Vivo

An Allosteric Modulator of PAR1 Demonstrates Selective Inhibition of G Protein Coupling and Impairs Thrombus Formation In Vivo

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American Society of Hematology

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American Society of Hematology

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