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Journal Articles

Comprehensive Sequence Analysis of Relapse and Refractory Pediatric Acute Myeloid Leukemia Identifies miRNA and mRNA Transcripts Associated with Treatment Resistance - a Report from the COG/NCI-Target AML Initiative

Emilia L. Lim, Diane L. Trinh, MSc, Rhonda E. Ries, MA, Yussanne Ma, PhD, James Topham, Maya D. Hughes, MD, Erin Pleasance, PhD, Andrew J. Mungall, PhD, Richard Moore, PhD, Yongjun Zhao, PhD, Daniela S. Gerhard, PhD, Vivian Oehler, MD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Todd A. Alonzo, PhD, Robert J. Arceci, MD PhD, Soheil Meshinchi, MD PhD, Marco A. Marra, PhD

Blood (2015) 126 (23): 687.

https://doi.org/10.1182/blood.V126.23.687.687

Published: 2015

Journal Articles

PIM3-SCO2 Fusion Is a Novel Transcription-Induced Chimera That Is Highly Prevalent In Childhood AML

Julia Kuhn, BA, Daoud Meerzaman, MD, Rhonda E. Ries, MA, Filippo Milano, MD, PhD, Alan S. Gamis, MD, MPH, Todd A. Alonzo, PhD, Jaime Guidry-Auvil, Ph.D., Tanja M. Davidsen, PhD, Malcolm A. Smith, MD, PhD, Yan Chunhua, Chih Hao Hsu, Cu Nguyen, Daniela S. Gerhard, Ph.D., Daniel Wai, Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2013) 122 (21): 2549.

https://doi.org/10.1182/blood.V122.21.2549.2549

Published: 2013

Journal Articles

Insights Into Diagnosis and Etiology of Diamond Blackfan Anemia by Analysis of Pre-rRNA Processing

Ross Fisher, MD, Adrianna Henson, Paola Quarello, MD, Anna Aspesi, PhD, Jason E Farrar, MD, Robert J. Arceci, MD, PhD, David M. Bodine, PhD, Irma Dianzani, MD PhD, Jeffrey M. Lipton, MD, PhD, Ugo Ramenghi, MD, Adrianna Vlachos, MD, Steven R Ellis, PhD

Blood (2012) 120 (21): 3476.

https://doi.org/10.1182/blood.V120.21.3476.3476

Published: 2012

Journal Articles

Integrative Network Analysis of Pediatric AML Whole Genomes, cDNA Expression and Clinical Data Elements Reveals Shared As Well As t(8;21), Inv16 and MLL Specific Pathways; A Report From COG/NCI Target AML Initiative

Hamid Bolouri, PhD, Rhonda E. Ries, MA, Ranjani Ramamurthy, MS, Todd A. Alonzo, PhD, Jaime M. Guidry Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Alan S. Gamis, MD, MPH, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2012) 120 (21): 3519.

https://doi.org/10.1182/blood.V120.21.3519.3519

Published: 2012

Journal Articles

Clinically Significant Mutations, Deletions and Translocations Involving ETV6 Identified by Whole Genome and Whole Exome Sequencing; Report From NCI/COG Target AML Initiative

Heather L. Helton, MD, Rhonda E. Ries, MA, Todd A. Alonzo, PhD, Robert B. Gerbing, M.A., Lisa R. Trevino, PhD, Jason Farrar, M.D., Jaime M. Guidry Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Donna M. Muzny, Alan S. Gamis, MD, MPH, Janet Franklin, MD, MPH, David A. Wheeler, PhD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2012) 120 (21): 125.

https://doi.org/10.1182/blood.V120.21.125.125

Published: 2012

Journal Articles

Interim Report of a Randomized, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of Decitabine As an Epigenetic Priming Agent When Combined with Induction Chemotherapy in Pediatric Patients (pts) with Newly Diagnosed Acute Myelogenous Leukemia (AML)

Lia Gore, MD, Margaret E. Macy, M.D., Francoise Mechinaud, MD, Aru Narendran, MD, PhD, Frank Alvaro, MD, Carola A.S. Arndt, MD, Phillip Barnette, MD, Jessica Boklan, MD, Todd Cooper, DO, Laura Martin, MD, W Tcheng, MD, Peter Tarassoff, MD, Mark M Jones, MD, Soheil Meshinchi, MD, PhD, Robert J. Arceci, MD, PhD

Blood (2012) 120 (21): 1517.

https://doi.org/10.1182/blood.V120.21.1517.1517

Published: 2012

Journal Articles

Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study

Soheil Meshinchi, MD, PhD, Rhonda E. Ries, MA, Lisa R. Trevino, PhD, Oliver A. Hampton, PhD, Todd Alonzo, PhD, Jason E. Farrar, MD, Jaime M. Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, PhD, Donna M. Muzny, Alan S. Gamis, MD, MPH, Heather L. Helton, MD, David A. Wheeler, PhD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD

Blood (2012) 120 (21): 123.

https://doi.org/10.1182/blood.V120.21.123.123

Published: 2012

Journal Articles

Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children

Michael Ochs, Ph.D., Jason Farrar, M.D., Michael Considine, M.S., Rhonda E. Ries, MA, Lisa R. Trevino, PhD, Todd A. Alonzo, PhD, Jaime Guidry-Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Donna M. Muzny, Alan S. Gamis, MD, MPH, David A. Wheeler, PhD, Heather L. Helton, MD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Soheil Meshinchi, MD, PhD, Robert J. Arceci, MD, PhD

Blood (2012) 120 (21): 1287.

https://doi.org/10.1182/blood.V120.21.1287.1287

Published: 2012

Journal Articles

5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide

Adrianna Vlachos, MD, Jason Farrar, MD, Eva Atsidaftos, MS, Ellen Muir, RN, CNS, Thomas C. Markello, MD, PhD, Sharon Singh, MD, Johnson M. Liu, MD, Steven Ellis, PhD, Robert J. Arceci, MD, PhD, David M. Bodine, PhD, Jeffrey Michael Lipton, MD, PhD

Blood (2010) 116 (21): LBA-2.

https://doi.org/10.1182/blood.V116.21.LBA-2.LBA-2

Published: 2010

Journal Articles

Single Cell Network Profiling (SCNP) Signatures Predict Response to Induction Therapy and Relapse Risk In Pediatric Patients with Acute Myeloid Leukemia: Children's Oncology Group (COG) Study POG-9421

Norman J. Lacayo, MD, Aileen Cohen, Ph.D., M.D., Matt Westfall, Ph.D., Alan Lackey, MS, Xiaohua (Robert) Xin, Ph.D., M.D., Urte Gayko, Ph.D., Santosh Putta, Ph.D., Soheil Meshinchi, MD, PhD, Susana C. Raimondi, PhD, Todd A. Alonzo, PhD, Robert J. Arceci, MD, PhD, Yaddanapudi Ravindranath, MD, Gary Van Houten Dahl, MD, Alessandra Cesano, MD

Blood (2010) 116 (21): 954.

https://doi.org/10.1182/blood.V116.21.954.954

Published: 2010

Journal Articles

5q- Syndrome In a Child: Is This Acquired Diamond Blackfan Anemia (DBA)?

Adrianna Vlachos, MD, Jason Farrar, MD, Eva Atsidaftos, MS, Ellen Muir, MSN, CNS, Thomas C. Markello, MD, PhD, Sharon Singh, MD, Johnson M. Liu, MD, Steven Ellis, PhD, Robert J. Arceci, MD, PhD, David M. Bodine, PhD, Jeffrey Michael Lipton, MD, PhD

Blood (2010) 116 (21): 4430.

https://doi.org/10.1182/blood.V116.21.4430.4430

Published: 2010

Journal Articles

SNP Array Genotyping Reveals Constitutional and Mosaic Losses of Ribosomal Protein Gene Regions In Patients with Diamond Blackfan Anemia without Ribosomal Protein Gene Mutations.

Jason E. Farrar, MD, Adrianna Vlachos, MD, Eva Atsidaftos, MS, Hannah Carlson-Donohoe, Steven R. Ellis, PhD, Thomas C. Markello, MD, PhD, Robert J. Arceci, MD, PhD, Jeffrey M. Lipton, MD, PhD, David M. Bodine, PhD

Blood (2010) 116 (21): 1168.

https://doi.org/10.1182/blood.V116.21.1168.1168

Published: 2010

Journal Articles

Selective and Titratable Effects On AML Genome Wide Methylation Patterning, Transcription and Clonogenicity Using Very Low Concentrations of 5-Aza-2'deoxycytidine.

Elisabeth Heuston, Jason E. Farrar, MD, Timothy Triche, M.D., Ph.D., Jonathan Buckley, Poul Sorensen, M.D., Ph.D., C. Patrick Reynolds, Gregory Reaman, MD, Vasan Yegnasubramanian, M.D., Ph.D., Robert J. Arceci, MD, PhD

Blood (2009) 114 (22): 2385.

https://doi.org/10.1182/blood.V114.22.2385.2385

Published: 2009

Journal Articles

Differential Down-Regulation of RPL35a in Human Bone Marrow Progenitors Demonstrates a p53 Independent Mechanism Mediating the Diamond Blackfan Anemia Phenotype.

Emi Caywood, M.D., Jason E. Farrar, MD, Jeffrey Michael Lipton, MD, PhD, Robert J. Arceci, MD, PhD

Blood (2009) 114 (22): 1096.

https://doi.org/10.1182/blood.V114.22.1096.1096

Published: 2009

Journal Articles

COG AAML03P1: Efficacy and Safety in a Pilot Study of Intensive Chemotherapy Including Gemtuzumab in Children Newly Diagnosed with Acute Myeloid Leukemia (AML)

Janet Franklin, MD, MPH, Todd Alonzo, PhD, Craig Alan Hurwitz, MD, Robert Gerbing, Franklin Smith, Robert J. Arceci, MD, PhD, James Feusner, MD, Prasad Mathew, MD, Robert Iannone, MD, Soheil Meshinchi, MD, PhD, Robert Lavey, MD, MPH, Joetta D Wallace, RN, Kelly Anderson, RN, Laura Winter, PharmD, Kathleen Glick, BA, Betty Hirsch, MD, Susana C. Raimondi, PhD, Alan Gamis, MD

Blood (2008) 112 (11): 136.

https://doi.org/10.1182/blood.V112.11.136.136

Published: 2008

Journal Articles

Yeast Models of Diamond Blackfan Anemia and Shwachman Diamond Syndrome Differ in Their Effect on the Synthesis and Function of Ribosomal Subunits.

Steven R Ellis, PhD, Joseph B. Moore, IV, Johnson M. Liu, MD, Robert J. Arceci, MD, PhD, Jason E. Farrar, MD

Blood (2008) 112 (11): 2044.

https://doi.org/10.1182/blood.V112.11.2044.2044

Published: 2008

Journal Articles

Cell Death Regulatory Gene Expression Correlates with MLL Rearrangement Status and Prognostic Clinical Covariates in Acute Leukemia in Infants.

Alena Y. Zhang, PharmD, PhD, Blaine W. Robinson, PhD, Kajia Kao, PhD, Kathryn Behling, MD, PhD, Meenakshi Devidas, PhD, Todd Alonzo, PhD, Susana C. Raimondi, PhD, Andrew Carroll, PhD, Robert J. Arceci, MD, PhD, Alan Gamis, MD, Stephen P. Hunger, MD, Gregory H. Reaman, MD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Li-San Wang, PhD, Carolyn A. Felix, MD

Blood (2008) 112 (11): 2255.

https://doi.org/10.1182/blood.V112.11.2255.2255

Published: 2008

Journal Articles

Minimizing Therapy for Patients with Acute Promyelocytic Leukemia: Efficacy of Single Cycle of Arsenic-Based Consolidation Therapy.

Steven D. Gore, MD, Lawrence Morris, MD, Ivana Gojo, MD, Marcel P. Devetten, MD, Katarzyna Jamieson, MD, Mikkael A. Sekeres, MD, MS, Robert J. Arceci, MD, PhD, Robert L. Redner, MD, Tianna Dauses, BSN, Esther L Schachter-Tokarz, Ibitayo Owoeye, MD, Robert E. Gallagher, MD

Blood (2008) 112 (11): 1932.

https://doi.org/10.1182/blood.V112.11.1932.1932

Published: 2008

Journal Articles

Telomere Length Shortening in Langerhans Cell Histiocytosis.

Gitanjali I. Bechan, MD, Alan K. Meeker, PhD, Angelo M. DeMarzo, MD, PhD, Frederick Racke, MD, PhD, Ronald Jaffe, MBBCh, Elizabeth Sugar, PhD, Robert J. Arceci, MD, PhD

Blood (2007) 110 (11): 2411.

https://doi.org/10.1182/blood.V110.11.2411.2411

Published: 2007

Journal Articles

The MMSET Gene Contributes to the Growth, Adhesion, and Tumorigencitiy of t(4;14) Multiple Myeloma Cells.

Josh Lauring, MD, PhD, Abde M. Abukhdeir, PhD, Hiroyuki Konishi, MD, PhD, Joseph P. Garay, M.S., John P. Gustin, B.S., Qiuju Wang, M.S., Robert J. Arceci, MD, PhD, William Matsui, MD, Ben H. Park, MD, PhD

Blood (2007) 110 (11): 2636.

https://doi.org/10.1182/blood.V110.11.2636.2636

Published: 2007

NARROW

Comprehensive Sequence Analysis of Relapse and Refractory Pediatric Acute Myeloid Leukemia Identifies miRNA and mRNA Transcripts Associated with Treatment Resistance - a Report from the COG/NCI-Target AML Initiative

PIM3-SCO2 Fusion Is a Novel Transcription-Induced Chimera That Is Highly Prevalent In Childhood AML

Insights Into Diagnosis and Etiology of Diamond Blackfan Anemia by Analysis of Pre-rRNA Processing

Integrative Network Analysis of Pediatric AML Whole Genomes, cDNA Expression and Clinical Data Elements Reveals Shared As Well As t(8;21), Inv16 and MLL Specific Pathways; A Report From COG/NCI Target AML Initiative

Clinically Significant Mutations, Deletions and Translocations Involving ETV6 Identified by Whole Genome and Whole Exome Sequencing; Report From NCI/COG Target AML Initiative

Interim Report of a Randomized, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of Decitabine As an Epigenetic Priming Agent When Combined with Induction Chemotherapy in Pediatric Patients (pts) with Newly Diagnosed Acute Myelogenous Leukemia (AML)

Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study

Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children

5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide

Single Cell Network Profiling (SCNP) Signatures Predict Response to Induction Therapy and Relapse Risk In Pediatric Patients with Acute Myeloid Leukemia: Children's Oncology Group (COG) Study POG-9421

5q- Syndrome In a Child: Is This Acquired Diamond Blackfan Anemia (DBA)?

SNP Array Genotyping Reveals Constitutional and Mosaic Losses of Ribosomal Protein Gene Regions In Patients with Diamond Blackfan Anemia without Ribosomal Protein Gene Mutations.

Selective and Titratable Effects On AML Genome Wide Methylation Patterning, Transcription and Clonogenicity Using Very Low Concentrations of 5-Aza-2'deoxycytidine.

Differential Down-Regulation of RPL35a in Human Bone Marrow Progenitors Demonstrates a p53 Independent Mechanism Mediating the Diamond Blackfan Anemia Phenotype.

COG AAML03P1: Efficacy and Safety in a Pilot Study of Intensive Chemotherapy Including Gemtuzumab in Children Newly Diagnosed with Acute Myeloid Leukemia (AML)

Yeast Models of Diamond Blackfan Anemia and Shwachman Diamond Syndrome Differ in Their Effect on the Synthesis and Function of Ribosomal Subunits.

Cell Death Regulatory Gene Expression Correlates with MLL Rearrangement Status and Prognostic Clinical Covariates in Acute Leukemia in Infants.

Minimizing Therapy for Patients with Acute Promyelocytic Leukemia: Efficacy of Single Cycle of Arsenic-Based Consolidation Therapy.

Telomere Length Shortening in Langerhans Cell Histiocytosis.

The MMSET Gene Contributes to the Growth, Adhesion, and Tumorigencitiy of t(4;14) Multiple Myeloma Cells.

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American Society of Hematology

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American Society of Hematology

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