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Journal Articles

A Systems Immunology Approach to Graft-Versus-Host Disease

Pedro Santos e Sousa, MD, Cara Lomas, PhD, Hannah Shorrock, Thomas Conlan, Terry K Means, PhD, Vincent Plagnol, PhD, Clare L Bennett, PhD, Ronjon Chakraverty, MD PhD

Blood (2014) 124 (21): 3812.

https://doi.org/10.1182/blood.V124.21.3812.3812

Published: 2014

Journal Articles

T Cells Engineered For Resistance To Mycophenolate Mofetil Demonstrate Enhanced Expansion and Improved Tumour Control In Immunosuppressed Hosts

James Edward Griffin, MD, Shoa-An Xue, Benjamin J Carpenter, Pedro Velica, PhD, Angelika Holler, Sara Ghorashian, MD, Emma Nicholson, MD, Martin Pule, MD, Ronjon Chakraverty, MD, PhD

Blood (2013) 122 (21): 4486.

https://doi.org/10.1182/blood.V122.21.4486.4486

Published: 2013

Journal Articles

Tuning Of mTOR In Therapeutic T Cells As A Strategy To Manufacture Effector and Memory T Cells

Velica Pedro, PhD, Mathias Zech, Hans Stauss, MD, PhD, Ronjon Chakraverty, MD, PhD

Blood (2013) 122 (21): 4488.

https://doi.org/10.1182/blood.V122.21.4488.4488

Published: 2013

Journal Articles

Endogenous T Cell Receptors Drive Non-Specific Suppression by Foxp3 MHC Class I-Restricted T Cell Receptor-Transduced Polyclonal CD4+ T Cells in Models of Graft-Versus-Host Disease.

Benjamin J Uttenthal, MD, Emma Nicholson, MD, Ben Carpenter, MD, Sara Ghorashian, MD, Graham P Wright, PhD, Barry R Flutter, PhD, Shao-An Xue, PhD, Ronjon Chakraverty, MD, PhD, Emma Morris, MD, PhD

Blood (2012) 120 (21): 3152.

https://doi.org/10.1182/blood.V120.21.3152.3152

Published: 2012

Journal Articles

In Vivo Selection of Mycophenolate Mofetil-Resistant T Cells for Adoptive Immunotherapy.

James Edward Griffin, MD, Ben Carpenter, MD, Emma Nicholson, MD, Shao-an Xue, PhD, Martin Pule, MD, Hans Stauss, MD, PhD, Ronjon Chakraverty, MD, PhD

Blood (2012) 120 (21): 3008.

https://doi.org/10.1182/blood.V120.21.3008.3008

Published: 2012

Journal Articles

Targeting Therapeutic T Cells to Tumour Niches.

Ben Carpenter, MD, Sara Ghorashian, MD, Emma Nicholson, MD, James Edward Griffin, MD, Maryam Ahmadi, PhD, Angelika Holler, Barry Flutter, PhD, Noha Edwards, Hans Stauss, MD, PhD, Emma Morris, MD, PhD, Ronjon Chakraverty, MD, PhD

Blood (2012) 120 (21): 3009.

https://doi.org/10.1182/blood.V120.21.3009.3009

Published: 2012

Journal Articles

CD4 Cells Engineered to Express an MHC Class I Restricted TCR Can Rescue CD8 Cells Tolerized to Tumour-Associated Antigens

Sara Ghorashian, MD, Ben Carpenter, MD, Angelika Holler, Emma Nicholson, MD, Maryam Ahmadi, PhD, Mathias Zech, MD, Clare Bennett, PhD, Shao-An Xue, PhD, Emma Morris, MD, PhD, Hans Stauss, MD, PhD, Ronjon Chakraverty, MD, PhD

Blood (2012) 120 (21): 952.

https://doi.org/10.1182/blood.V120.21.952.952

Published: 2012

Journal Articles

Enforced Co-Stimulation and Co-Inhibitory Blockade Synergize to Enhance the Functions of Exhausted CTL

Barry Flutter, PhD, Noha Edwards, Lei Zhang, Shivajanani Sivakumaran, Michael Croft, PhD, Megan Sykes, MD, Ronjon Chakraverty, MD, PhD

Blood (2011) 118 (21): 1911.

https://doi.org/10.1182/blood.V118.21.1911.1911

Published: 2011

Journal Articles

Host CD11c + Dendritic Cells Are Required for Priming the Lympho-Haematopoietic Graft-Versus-Host Response but Not Graft-Versus-Host Disease.

Farnaz Fallah-Arani, PhD, Janani Sivakumaran, Barry R Flutter, PhD, Clare Bennett, PhD, Ronjon Chakraverty, MD PhD

Blood (2009) 114 (22): 2450.

https://doi.org/10.1182/blood.V114.22.2450.2450

Published: 2009

Journal Articles

Adoptive Transfer of CMV-Specific Donor T Cells Following Allogeneic Transplantation Leads to Rapid and Safe Systemic Reconstitution.

Karl S Peggs, MD, Kirsty Thomson, MD, Edward Samuel, BSc, MSc, Gemma Dyer, Julie Armoogum, Kwok Pang, BSc, MSc, Ronjon Chakraverty, MD, PhD, Stephen Mackinnon, MD, Mark W Lowdell, PhD, FRCPath

Blood (2009) 114 (22): 44.

https://doi.org/10.1182/blood.V114.22.44.44

Published: 2009

Journal Articles

Donor Lymphocyte Infusions Induce High Response Rates and Durable Salvage in Relapsed Hodgkin Lymphoma Post T Cell Depleted Allogeneic Transplantation.

Karl S Peggs, MD, Kirsty Thomson, MD, Emma Morris, MD, Noha Chowdhry, Stephanie Verfuerth, PhD, Panos Kottaridis, Anthony H. Goldstone, FRCP, FRCPath, Kirit Ardeshna, MD, David Linch, Ronjon Chakraverty, MD, PhD, Stephen Mackinnon, MD

Blood (2009) 114 (22): 200.

https://doi.org/10.1182/blood.V114.22.200.200

Published: 2009

Journal Articles

Peripheral Alloantigen Drives Early Dysfunction and Eventual Exhaustion of CTL Following Delayed Donor Leukocyte Infusions.

Barry R Flutter, PhD, Farnaz Fallah-Arani, PhD, Clare Bennett, PhD, Janani Sivakumaran, Gordon J Freeman, PhD, Megan Sykes, MD, PhD, Ronjon Chakraverty, MD, PhD

Blood (2008) 112 (11): 2346.

https://doi.org/10.1182/blood.V112.11.2346.2346

Published: 2008

Journal Articles

Proliferation, Expansion, Effector Differentiation and Survival of GVH-Reactive T Cells Following Delayed DLI to Mixed Chimeras.

Ronjon Chakraverty, MD PhD, Jennifer Buchli, BA, Guiling Zhao, Megan Sykes, MD

Blood (2004) 104 (11): 594.

https://doi.org/10.1182/blood.V104.11.594.594

Published: 2004

Journal Articles

Requirement for CD4 Help for Optimal GVL Effects of Alloreactive T Cells Given to Established Mixed Chimeras but Not Freshly Irradiated Mice.

Hyeon-Seok Eom, MD, PhD, Ronjon Chakraverty, MD, PhD, Jessica Sachs, MD, Guiling Zhao, Megan Sykes, MD

Blood (2004) 104 (11): 3044.

https://doi.org/10.1182/blood.V104.11.3044.3044

Published: 2004

Journal Articles

Host Environment Dictates the Outcome Following Transfer of Graft-Versus-Host Reactive Effector/Memory T Cells.

Ronjon Chakraverty, MD, PhD, Jennifer Buchli, BA, Guiling Zhao, Richard Hsu, Megan Sykes, MD

Blood (2004) 104 (11): 3046.

https://doi.org/10.1182/blood.V104.11.3046.3046

Published: 2004

Journal Articles

Sequential Blockade and Engagement of Co-Stimulatory Pathways: A Potential Strategy for Amplifying Graft-Versus-Leukemia Responses without GVHD.

Ronjon Chakraverty, MD PhD, Jennifer Buchli, BA, Guiling Zhao, Richard Hsu, Michael Croft, PhD, Megan Sykes, MD

Blood (2004) 104 (11): 3075.

https://doi.org/10.1182/blood.V104.11.3075.3075

Published: 2004

NARROW

A Systems Immunology Approach to Graft-Versus-Host Disease

T Cells Engineered For Resistance To Mycophenolate Mofetil Demonstrate Enhanced Expansion and Improved Tumour Control In Immunosuppressed Hosts

Tuning Of mTOR In Therapeutic T Cells As A Strategy To Manufacture Effector and Memory T Cells

Endogenous T Cell Receptors Drive Non-Specific Suppression by Foxp3 MHC Class I-Restricted T Cell Receptor-Transduced Polyclonal CD4+ T Cells in Models of Graft-Versus-Host Disease.

In Vivo Selection of Mycophenolate Mofetil-Resistant T Cells for Adoptive Immunotherapy.

Targeting Therapeutic T Cells to Tumour Niches.

CD4 Cells Engineered to Express an MHC Class I Restricted TCR Can Rescue CD8 Cells Tolerized to Tumour-Associated Antigens

Enforced Co-Stimulation and Co-Inhibitory Blockade Synergize to Enhance the Functions of Exhausted CTL

Host CD11c + Dendritic Cells Are Required for Priming the Lympho-Haematopoietic Graft-Versus-Host Response but Not Graft-Versus-Host Disease.

Adoptive Transfer of CMV-Specific Donor T Cells Following Allogeneic Transplantation Leads to Rapid and Safe Systemic Reconstitution.

Donor Lymphocyte Infusions Induce High Response Rates and Durable Salvage in Relapsed Hodgkin Lymphoma Post T Cell Depleted Allogeneic Transplantation.

Peripheral Alloantigen Drives Early Dysfunction and Eventual Exhaustion of CTL Following Delayed Donor Leukocyte Infusions.

Proliferation, Expansion, Effector Differentiation and Survival of GVH-Reactive T Cells Following Delayed DLI to Mixed Chimeras.

Requirement for CD4 Help for Optimal GVL Effects of Alloreactive T Cells Given to Established Mixed Chimeras but Not Freshly Irradiated Mice.

Host Environment Dictates the Outcome Following Transfer of Graft-Versus-Host Reactive Effector/Memory T Cells.

Sequential Blockade and Engagement of Co-Stimulatory Pathways: A Potential Strategy for Amplifying Graft-Versus-Leukemia Responses without GVHD.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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