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Rui Liu, Ph.D.
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Journal Articles

A Novel Perspective on Stem Cells, Tissue Senescence and Aging: Pluripotent Very Small Embryonic-Like Stem Cells (VSELs) and Hematopoietic Stem Cells (HSCs) Are Prematurely Depleted in Adult Bone Marrow (BM) in Response to Prolonged Growth Hormone/Insulin-Like Growth Factor-1 Signaling (IIS) and Chronic Increase in Caloric Uptake

Magda Kucia, Ph.D., Janina Ratajczak, MD, PhD, Dong-Myung Shin, PhD, Rui Liu, Ph.D., Michal Masternak, Ph.D., Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 4818.
https://doi.org/10.1182/blood.V118.21.4818.4818
Published: 2011
Journal Articles

A Novel View of Paroxysmal Nocturnal Hemoglobinuria (PNH) Pathogenesis: Do Pathologic PNH Hematopoietic Stem/Progenitor Cells (HSPCs) Displace Normal HSPCs From Their Niches in Bone Marrow Because They Are More Motile Due to Defective Adhesion and Enhanced Migratory Properties?

Janina Ratajczak, MD, PhD, Rui Liu, Ph.D., Nagendra Natarajan, MD, MPH, Jaroslaw P. Maciejewski, MD, PhD, Vivek R. Sharma, MD, FRCPA, Mariusz Z Ratajczak, MD, PhD, DSc
Journal: Blood
Blood (2011) 118 (21): 732.
https://doi.org/10.1182/blood.V118.21.732.732
Published: 2011
Journal Articles

Single Cell Level Genome-Wide Gene Expression Analysis of Bone Marrow-Derived Oct-4 + very Small Embryonic-Like Stem Cells (VSELs) Revealed That a Polycomb Group Protein Ezh2 Regulates VSELs Pluripotency by Maintaining Bivalent Domains At Promoters of Important Homeodomain-Containing Developmental Transcription Factors

Magda Kucia, Ph.D., Rui Liu, Ph.D., Kasia Mierzejewska, MS, Wan Wu, Ph.D., Janina Ratajczak, MD, PhD, Dong-Myung Shin, PhD, Mariusz Z Ratajczak
Journal: Blood
Blood (2011) 118 (21): 2345.
https://doi.org/10.1182/blood.V118.21.2345.2345
Published: 2011
Journal Articles

Long-Term In Vivo Studies in Mice Unexpectedly Reveal That Prolonged Growth Hormone (GH) and Insulin/Insulin-Like Growth Factor-1 (IGF-1) Signaling Have a Negative Effect on Normal Bone Marrow Hematopoiesis – Implications for GH-Based “rejuvenation” Therapies,

Janina Ratajczak, MD, PhD, Rui Liu, Ph.D., Magda Kucia, Ph.D., Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, MD, PhD, DSc
Journal: Blood
Blood (2011) 118 (21): 3422.
https://doi.org/10.1182/blood.V118.21.3422.3422
Published: 2011