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Journal Articles

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Julia Frede, PhD MPhil, Praveen Anand, PhD, Andrew J. Yee, MD, Tushara Vijaykumar, Monica S. Nair, Johannes M. Waldschmidt, MD, Sayalee V. Potdar, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Guangwu Guo, PhD, Samantha J. Shapiro, Mason L. Mann, Robb S Friedman, MD, Brea C. Lipe, MD, Erica L. Campagnaro, MD, Craig E. Cole, MD, Elizabeth K. O'Donnell, MD, Thomas Guerrero, MD, Omar Nadeem, MD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Noopur Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3091.
https://doi.org/10.1182/blood-2019-130247
Published: 2019
Journal Articles

Circulating Tumor DNA in the Peripheral Blood As Early Predictor of Clinical Outcome in Relapsed/ Refractory Multiple Myeloma

Johannes M. Waldschmidt, MD, Andrew J. Yee, MD, Tushara Vijaykumar, Julia Frede, PhD MPhil, Praveen Anand, PhD, Sayalee Potdar, Monica S. Nair, Antonis Kokkalis, PhD MSc, Jake A. Kloeber, Guangwu Guo, PhD, Samantha J. Shapiro, Mason L. Mann, Robb S Friedman, MD, Brea C. Lipe, MD, Erica L. Campagnaro, MD, Elizabeth K. O'Donnell, MD, Thomas Guerrero, MD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Noopur S. Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4350.
https://doi.org/10.1182/blood-2019-131037
Published: 2019
Journal Articles

Targeted FGFR Inhibition Results in Hematologic and Cytogenetic Remission in a Myeloid Neoplasm Driven By a Novel PCM1-FGFR1 Fusion: Data from an Expanded Access Program

Monica Kasbekar, Valentina Nardi, MD, Paola Dal Cin, Andrew M. Brunner, MD, Yi-Bin Chen, Christine Connolly, Amir T. Fathi, MD, Julia Foster, ANP, Molly Macrae, Steven L McAfee, MD, Kristin McGregor, Rupa Narayan, Aura Y. Ramos, Tina T. Som, RN, Megan Vartanian, RN, Robb S Friedman, MD, Karim Benhadji, MD MSC, Gabriela S. Hobbs, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5371.
https://doi.org/10.1182/blood-2019-124100
Published: 2019
Journal Articles

A Phase II Study of Elotuzumab in Combination with Pomalidomide, Bortezomib, and Dexamethasone in Relapsed and Refractory Multiple Myeloma

Andrew J. Yee, MD, Jacob P. Laubach, MD, Erica L. Campagnaro, MD, Brea C. Lipe, MD, Omar Nadeem, MD, Robb S Friedman, MD, Craig E. Cole, MD, Elizabeth K. O'Donnell, MD, Giada Bianchi, MD, Andrew R. Branagan, MD, Samantha J. Shapiro, Cynthia C. Harrington, NP, Jill N. Burke, NP, Marilyn T. Gammon, RN, Kathleen J. Lively, RN, Cassandra A. Thorburn, Mason L. Mann, Jens G. Lohr, MD PhD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Noopur S. Raje, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3169.
https://doi.org/10.1182/blood-2019-124870
Published: 2019
Journal Articles

The PI3K Inhibitor GDC-0941 Attenuates Disease in a Kras G12D Mouse Model of CMML and JMML.

Jon Akutagawa, B.S., Monique Dail, PhD, Lori S Friedman, PhD, Kevin M. Shannon, MD, Deepak Sampath, PhD, Benjamin S. Braun, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2862.
https://doi.org/10.1182/blood.V120.21.2862.2862
Published: 2012
Journal Articles

A Critical Role for PIM2 Kinase in Multiple Myeloma Through NF-κB Activation

Veerendra Munugalavadla, PhD, Leanne Berry, Jae Chang, Geoffrey Del Rosario, Jake Drummond, Changchun Du, Karen Fitzgerald, Lori S Friedman, Stephen E Gould, Heather Maecker, John Moffat, Dionysos Slaga, Xiaojing Xiaojing, Kristina West, Shang-Fan Yu, Allen J. Ebens, PhD
Journal: Blood
Blood (2011) 118 (21): 1839.
https://doi.org/10.1182/blood.V118.21.1839.1839
Published: 2011
Journal Articles

In Vivo Monitoring of Red Cell Redox Status to Screen for Potential Hematotoxicity of Anti-Malarial Drugs

Xiuling Xu, PhD, Jeff S. Friedman, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2099.
https://doi.org/10.1182/blood.V118.21.2099.2099
Published: 2011
Journal Articles

A novel approach for in vivo measurement of mouse red cell redox status

Brief Report
Xiuling Xu, Katharina von Löhneysen, Katrin Soldau, Deborah Noack, Andrew Vu, Jeffrey S. Friedman
Journal: Blood
Blood (2011) 118 (13): 3694–3697.
https://doi.org/10.1182/blood-2011-03-342113
Published: 2011
Includes: Supplemental data
Journal Articles

Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans

Duane A. Mitchell, Xiuyu Cui, Robert J. Schmittling, Luis Sanchez-Perez, David J. Snyder, Kendra L. Congdon, Gary E. Archer, Annick Desjardins, Allan H. Friedman, Henry S. Friedman, James E. Herndon, II, Roger E. McLendon, David A. Reardon, James J. Vredenburgh, Darell D. Bigner, John H. Sampson
Journal: Blood
Blood (2011) 118 (11): 3003–3012.
https://doi.org/10.1182/blood-2011-02-334565
Published: 2011
Includes: Supplemental data
Journal Articles

A Selective PIM Kinase Inhibitor Is Highly Active In Multiple Myeloma: Mechanism of Action and Signal Transduction Studies

Veerendra Munugalavadla, PhD, Leanne Berry, Yung-Hsiang Chen, Gauri Deshmukh, Jake Drummond, Changchun Du, Michael Eby, Karen Fitzgerald, Lori S. Friedman, Stephen E. Gould, Jane R. Kenny, Heather Maecker, John Moffat, Marina Moskalenko, Patricia Pacheco, Alham Saadat, Dion Slaga, Laura Sun, Gina Wang, Yagai Yang, Allen J. Ebens, PhD
Journal: Blood
Blood (2010) 116 (21): 4084.
https://doi.org/10.1182/blood.V116.21.4084.4084
Published: 2010
Journal Articles

Metabolomic Evaluation of Normal, In Vivo, Red Cell Aging

Katrin Soldau, Katharina von Loehneysen, PhD, Xiuling Xu, PhD, Jeff S. Friedman, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2035.
https://doi.org/10.1182/blood.V116.21.2035.2035
Published: 2010
Journal Articles

A Novel Approach for In Vivo Measurement of Red Cell Redox Status

Xiuling Xu, PhD, Katharina von Loehneysen, PhD, Deborah Noack, Andrew Vu, Jeff S. Friedman, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2036.
https://doi.org/10.1182/blood.V116.21.2036.2036
Published: 2010
Journal Articles

Comparison of Erythropoietin, GDF-15, IL-6 and Hepcidin Levels In a Large Cohort of Elderly Individuals with Anemia of Known and Unknown Etiology

Katharina von Loehneysen, PhD, Xiuling Xu, PhD, Pauline Lee, PhD, Jill Waalen, MD, Jeff S. Friedman, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2037.
https://doi.org/10.1182/blood.V116.21.2037.2037
Published: 2010
Journal Articles

A Selective PIM Kinase Inhibitor Is Highly Active In Multiple Myeloma: The Biology of Single Agent and PI3K/AKT/mTOR Combination Activity

Allen J. Ebens, PhD, Leanne Berry, Yung-Hsiang Chen, Gauri Deshmukh, Jake Drummond, Changchun Du, Michael Eby, Karen Fitzgerald, Lori S. Friedman, Stephen E. Gould, Jane R. Kenny, Heather Maecker, John Moffat, Marina Moskalenko, Patricia Pacheco, Alham Saadat, Dion Slaga, Laura Sun, Gina Wang, Yagai Yang, Veerendra Munugalavadla, PhD
Journal: Blood
Blood (2010) 116 (21): 3001.
https://doi.org/10.1182/blood.V116.21.3001.3001
Published: 2010
Journal Articles

A Role for the Transcriptional Coactivator PRC1 in Mitochondrial Biogenesis During Erythroid Development.

Xiuling Xu, Ph.D., Jeff S. Friedman, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3642.
https://doi.org/10.1182/blood.V114.22.3642.3642
Published: 2009
Journal Articles

Mitochondria and Hematologic Disorders.

Jeff S. Friedman, MD, PhD
Journal: Blood
Blood (2009) 114 (22): SCI-3.
https://doi.org/10.1182/blood.V114.22.SCI-3.SCI-3
Published: 2009
Journal Articles

Differential Expression of 2 Familial Parkinson's Disease Transcripts (DJ-1 and SNCA) in Normal and Oxidant Stressed Erythroid Precursors.

Xiuling Xu, Ph.D., Jeff S. Friedman, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3010.
https://doi.org/10.1182/blood.V114.22.3010.3010
Published: 2009
Journal Articles

GASing up iron delivery via STAT5

Jeffrey S. Friedman
Journal: Blood
Blood (2008) 112 (5): 1553–1554.
https://doi.org/10.1182/blood-2008-07-167965
Published: 2008
Journal Articles

Ex-Vivo Expansion and mRNA Transfection of Cord Blood Derived Natural Killer Cells with Preserved Cytotoxicity.

Hande H. Tuncer, MD, Monica M. Betancur, MSc., Laurent H. Boissel, PhD, Robb S. Friedman, MD, Hans G. Klingemann, MD,PhD
Journal: Blood
Blood (2006) 108 (11): 3659.
https://doi.org/10.1182/blood.V108.11.3659.3659
Published: 2006
Journal Articles

A Method for Rapid Purification of Murine Siderocytes.

Florent M. Martin, PhD, Gabriela Bydlon, Megan L. Welsh, Jeffrey S. Friedman, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 3703.
https://doi.org/10.1182/blood.V106.11.3703.3703
Published: 2005