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Journal Articles

The MEK Inhibitor Trametinib Enhances Diverse T Cell Reconstitution with Suppressing Xenogeneic Graft-Versus-Host-Disease

Hidekazu Itamura, MD PhD, Hiroyuki Muranushi, MD, Takero Shindo, MD PhD, Kazutaka Kitaura, DVM, PhD, Seiji Okada, MD PhD, Tadasu Shin-I, PhD, Ryuji Suzuki, DVM, PhD, Akifumi Takaori-Kondo, MD PhD, Shinya Kimura, MD PhD

Blood (2019) 134 (Supplement_1): 1929.

https://doi.org/10.1182/blood-2019-128913

Published: 2019

Journal Articles

Efficacy of OR21, a Novel Oral Demethylating Agent in Chronic Myeloid Leukemia

Kazuharu Kamachi, MD, Hiroshi Ureshino, MD, Nao Yoshida, MD, Yuki Kurahashi, Tatsuro Watanabe, PhD, Seiji Okada, MD PhD, Shinya Kimura, MD PhD

Blood (2019) 134 (Supplement_1): 5365.

https://doi.org/10.1182/blood-2019-125460

Published: 2019

Journal Articles

Aberrant Regional DNA Hypermethylation As a Preventive and Therapeutic Target for Adult T-Cell Leukemia-Lymphoma

Tatsuro Watanabe, PhD, Hiroshi Ureshino, MD, Yuki Kurahashi, Yuki Fukuda-Kurahashi, Satoshi Yamashita, PhD, Toshikazu Ushijima, MD PhD, Seiji Okada, MD PhD, Eisaburo Sueoka, MD PhD, Shinya Kimura, MD PhD

Blood (2018) 132 (Supplement 1): 4175.

https://doi.org/10.1182/blood-2018-99-117536

Published: 2018

Journal Articles

The Analysis of HIV-Associated Lymphoma in Japan

Shotaro Hagiwara, MD PhD, Kentaro Yoshinaga, MD PhD, Masayuki Shiseki, MD, Junji Tanaka, MD PhD, Seiji Okada, MD PhD

Blood (2018) 132 (Supplement 1): 5315.

https://doi.org/10.1182/blood-2018-99-114060

Published: 2018

Journal Articles

OR21, a New Oral DNA Methyltransferase Inhibitor for Treatment of MDS and AML

Hiroshi Ureshino, MD, Tatsuro Watanabe, PhD, Yuki Kurahashi, Yuki Fukuda Kurahashi, Kaoru Tohyama, MD, Seiji Okada, MD PhD, Toshikazu Ushijima, MD PhD, Hiroshi Ureshino, MD PhD

Blood (2018) 132 (Supplement 1): 5499.

https://doi.org/10.1182/blood-2018-99-112362

Published: 2018

Journal Articles

EZH1/2, SWI/SNF, and MLL2 Dependent Heterochromatin Formation and Abnormal Transcriptome in Hematological Malignancies

Makoto Yamagishi, PhD, Dai Fujikawa, PhD, Makoto Hori, Daisuke Honma, PhD, Nobuaki Adachi, PhD, Seiichiro Kobayashi, MD, PhD, Masako Iwanaga, MD PhD MPH, Atae Utsunomiya, MD, Seiji Okada, MD, PhD, Kunihiro Tsukasaki, MD PhD, Kensei Tobinai, MD PhD, Kazushi Araki, D.V.M., PhD, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD, PhD

Blood (2017) 130 (Supplement 1): 1200.

https://doi.org/10.1182/blood.V130.Suppl_1.1200.1200

Published: 2017

Journal Articles

Mechanism of Pax5 Down-Regulation and Its Function in Primary Effusion Lymphoma

Hiroki Goto, MD, PhD, Ryusho Kariya, PhD, Eriko Kudo, PhD, Seiji Okada, MD, PhD

Blood (2017) 130 (Supplement 1): 3791.

https://doi.org/10.1182/blood.V130.Suppl_1.3791.3791

Published: 2017

Journal Articles

Prospective Clinical Study of High Dose Chemotherapy Followed By Peripheral Blood Stem Cell Transplantation for Relapsed or Refractory HIV-Associated Lymphoma

Shotaro Hagiwara, MDPhD, Tomoko Uehira, Hirokazu Nagai, MD PhD, Seiji Okada, MD, PhD, Junko Tanuma, Akiko Moriya Saito, MD PhD

Blood (2017) 130 (Supplement 1): 5214.

https://doi.org/10.1182/blood.V130.Suppl_1.5214.5214

Published: 2017

Journal Articles

Role of PU.1 Down-Regulation for the Development of Primary Effusion Lymphoma

Hiroki Goto, MD, PhD, Ryusho Kariya, PhD, Eriko Kudo, PhD, Yutaka Okuno, MD, PhD, Seiji Okada, MD, PhD

Blood (2016) 128 (22): 4091.

https://doi.org/10.1182/blood.V128.22.4091.4091

Published: 2016

Journal Articles

Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas

Makoto Yamagishi, PhD, Makoto Hori, Dai Fujikawa, PhD, Daisuke Honma, PhD, Nobuaki Adachi, PhD, Takeo Ohsugi, D.V.M., PhD, Kazumi Nakano, PhD, Makoto Nakashima, Seiichiro Kobayashi, MD, PhD, Masako Iwanaga, MD, PhD, Atae Utsunomiya, MD, PhD, Seiji Okada, MD, PhD, Kunihiro Tsukasaki, MD, Kensei Tobinai, MD, PhD, Kazushi Araki, D.V.M., PhD, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD PhD

Blood (2016) 128 (22): 462.

https://doi.org/10.1182/blood.V128.22.462.462

Published: 2016

Journal Articles

YM155 Induces Apoptosis through Proteasome-Dependent Degradation of MCL-1 in Primary Effusion Lymphoma

Yuki Kojima, MD, Fumihiko Hayakawa, MD PhD, Takanobu Morishita, MD, Keiki Sugimoto, PhD, Mizuho Iwase, Hideyuki Yamamoto, MD, Daiki Hirano, MD, Naoto Imoto, MD, Seiji Okada, MD, PhD, Hitoshi Kiyoi, MD PhD

Blood (2016) 128 (22): 3013.

https://doi.org/10.1182/blood.V128.22.3013.3013

Published: 2016

Journal Articles

Epigenetically Programmed Defenseless Signaling in Malignant Lymphoma

Makoto Yamagishi, PhD, Harutaka Katano, D.D.S., PhD, Tsunekazu Hishima, MD, PhD, Yasunori Ota, MD PhD, Seiji Okada, MD, PhD, Toshiki Watanabe, MD, PhD

Blood (2015) 126 (23): 1230.

https://doi.org/10.1182/blood.V126.23.1230.1230

Published: 2015

Journal Articles

Conditional Knockout of Sfpi1 in Post GC B and Plasma Cells Induces B Cell Lymphoma and Plasma Cell Neoplasm

Shinya Endo, MD, Hiromichi Yuki, MD PhD, Yoshihiro Komohara, MD PhD, Shikiko Ueno, MD PhD, Nao Nishimura, MD, Niina Ueno, MD, Hiro Tatetsu, MD PhD, Motohiro Takeya, MD PhD, Hiroyuki Hata, MD PhD, Seiji Okada, MD PhD, Daniel G. Tenen, MD, Hiroaki Mitsuya, MD PhD, Yutaka Okuno, MD PhD

Blood (2014) 124 (21): 29.

https://doi.org/10.1182/blood.V124.21.29.29

Published: 2014

Journal Articles

Evaluation Of Targeting CD47-SIRPα Using Primary Effusion Lymphoma Xenograft Mouse Model

Hiroki Goto, MD, Eriko Kudo, Kouki Matsuda, Ryusho Kariya, Manabu Taura, PhD, Seiji Okada, MD, PhD

Blood (2013) 122 (21): 1827.

https://doi.org/10.1182/blood.V122.21.1827.1827

Published: 2013

Journal Articles

PU.1-Induced Growth Arrest and Apoptosis in Classical Hodgkin Lymphoma Cells

Hiromichi Yuki, MD, Shikiko Ueno, MD, PhD, Hiroaki Niiro, MD, PhD, Hiro Tatetsu, MD, PhD, Hiroyuki Hata, MD, PhD, Toshiki Watanabe, MD, PhD, Seiji Okada, MD, Ph.D, Koichi Akashi, MD, PhD., Hiroaki Mitsuya, Professor, Yutaka Okuno, MD, PhD

Blood (2011) 118 (21): 2628.

https://doi.org/10.1182/blood.V118.21.2628.2628

Published: 2011

Journal Articles

Non-AIDS-Defining Hematologic Malignancies in HIV-Infected Patients: A Nationwide Epidemiologic Study in Japan

Shotaro Hagiwara, MD, PhD, Mihoko Yotsumoto, MD., Seiji Okada, MD, PhD

Blood (2011) 118 (21): 2183.

https://doi.org/10.1182/blood.V118.21.2183.2183

Published: 2011

Journal Articles

Rituxiamb Did Not Improve Clinical Outcomes In AIDS-Related Burkitt Lymphoma

Hideyuki Yamamoto, MD, Shotaro Hagiwara, MD, PhD, Yuki Kojima, MD, Asako Uehira, MD, Atsushi Ajisawa, MD, Akira Kitanaka, MD, PhD, Junko Tanuma, MD, Seiji Okada, MD, PhD, Hirokazu Nagai, MD, PhD

Blood (2011) 118 (21): 1629.

https://doi.org/10.1182/blood.V118.21.1629.1629

Published: 2011

Journal Articles

Whole Brain Radiation Alone Brings the Favorable Outcomes for AIDS Related Primary Central Nervous System Lymphoma (PCNSL) Especially with Good Performance Status in the HAART Era.

Hirokazu Nagai, MD, Takashi Odawara, MD, Atsushi Ajisawa, MD, Shotaro Hagiwara, MD, Tomoko Uehira, MD, Hideki Uchiumi, MD, Mihoko Yotsumoto, MD, Toshikazu Miyakawa, MD, Akira Watanabe, MD, Mitsuru Konishi, MD, Seiji Saito, MD, Souichirou Takahama, MD, Masao Tateyama, MD, Seiji Okada, MD

Blood (2009) 114 (22): 4751.

https://doi.org/10.1182/blood.V114.22.4751.4751

Published: 2009

Journal Articles

Identification and Characterization of a Hematopoietic Stem Cell Niche in Spleen

Takuo Mizukami, Ph.D, Isao Hamaguchi, MD, Ph.D, Kazuya Takizawa, Ph.D, Madoka Kuramitsu, Ph.D, Haruka Momose, Ph.D, Seishiro Naito, Ph.D, Atsuko Masumi, Ph.D, Seiji Okada, MD, Ph.D, Kazunari Yamaguchi, MD, Ph.D

Blood (2008) 112 (11): 1371.

https://doi.org/10.1182/blood.V112.11.1371.1371

Published: 2008

Journal Articles

Biscoclaurine Alkaloid Cepharanthine Inhibits the Growth of Primary Effusion Lymphoma In Vitro and In Vivo and Induce Apoptosis Via Suppressing the NK-κB Pathway.

Seiji Okada, MD, PhD, Naoko Makise, PhD, Masateru Hiyoshi, PhD, Shinya Suzu, PhD

Blood (2007) 110 (11): 4520.

https://doi.org/10.1182/blood.V110.11.4520.4520

Published: 2007

NARROW

The MEK Inhibitor Trametinib Enhances Diverse T Cell Reconstitution with Suppressing Xenogeneic Graft-Versus-Host-Disease

Efficacy of OR21, a Novel Oral Demethylating Agent in Chronic Myeloid Leukemia

Aberrant Regional DNA Hypermethylation As a Preventive and Therapeutic Target for Adult T-Cell Leukemia-Lymphoma

The Analysis of HIV-Associated Lymphoma in Japan

OR21, a New Oral DNA Methyltransferase Inhibitor for Treatment of MDS and AML

EZH1/2, SWI/SNF, and MLL2 Dependent Heterochromatin Formation and Abnormal Transcriptome in Hematological Malignancies

Mechanism of Pax5 Down-Regulation and Its Function in Primary Effusion Lymphoma

Prospective Clinical Study of High Dose Chemotherapy Followed By Peripheral Blood Stem Cell Transplantation for Relapsed or Refractory HIV-Associated Lymphoma

Role of PU.1 Down-Regulation for the Development of Primary Effusion Lymphoma

Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas

YM155 Induces Apoptosis through Proteasome-Dependent Degradation of MCL-1 in Primary Effusion Lymphoma

Epigenetically Programmed Defenseless Signaling in Malignant Lymphoma

Conditional Knockout of Sfpi1 in Post GC B and Plasma Cells Induces B Cell Lymphoma and Plasma Cell Neoplasm

Evaluation Of Targeting CD47-SIRPα Using Primary Effusion Lymphoma Xenograft Mouse Model

PU.1-Induced Growth Arrest and Apoptosis in Classical Hodgkin Lymphoma Cells

Non-AIDS-Defining Hematologic Malignancies in HIV-Infected Patients: A Nationwide Epidemiologic Study in Japan

Rituxiamb Did Not Improve Clinical Outcomes In AIDS-Related Burkitt Lymphoma

Whole Brain Radiation Alone Brings the Favorable Outcomes for AIDS Related Primary Central Nervous System Lymphoma (PCNSL) Especially with Good Performance Status in the HAART Era.

Identification and Characterization of a Hematopoietic Stem Cell Niche in Spleen

Biscoclaurine Alkaloid Cepharanthine Inhibits the Growth of Primary Effusion Lymphoma In Vitro and In Vivo and Induce Apoptosis Via Suppressing the NK-κB Pathway.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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