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Journal Articles

Bcr-Abl1 Kinase-Independent Upregulation of FcγRIIb Mediates Malignant Signaling That Is Critical for Leukemogenesis

Oliver Herrmann, Msc, Samantha Langer, Caroline Wessling, Michael Huber, PhD, Shaoguang Li, MD PhD, Tim Henrik Bruemmendorf, Steffen Koschmieder, Mirle Schemionek, PhD

Blood (2017) 130 (Supplement 1): 2862.

https://doi.org/10.1182/blood.V130.Suppl_1.2862.2862

Published: 2017

Journal Articles

Targeting Chronic Myeloid Leukemia Stem Cells through Pharmacological Inhibition of HIF-1α

Giulia Cheloni, PhD, Michele Tanturli, PhD, DeSouza Ho Ngoc, Yi Shan, MD, Ignazia Tusa, PhD, Elisabetta Rovida, PhD, Shaoguang Li, MD PhD, Persio Dello Sbarba, MD PhD

Blood (2016) 128 (22): 4235.

https://doi.org/10.1182/blood.V128.22.4235.4235

Published: 2016

Journal Articles

Inhibition of CML Stem Cells with an Alkaloid That Reduces β-Catenin

Shawnya J. Michaels, MS,MBA, Ngoc DeSouza, PhDCandidate, Yi Shan, MD, Shaoguang Li, MD PhD, Saira Bates, MBA

Blood (2016) 128 (22): 1882.

https://doi.org/10.1182/blood.V128.22.1882.1882

Published: 2016

Journal Articles

Eradication of Chronic Myelogenous Leukemia By Inactivation of the Polycomb Group Protein EZH2

Huafeng Xie, PhD, Cong Peng, PhD, Jun Qi, PhD, Giullia Cheloni, Partha Das, PhD, Jialiang Huang, PhD, Minh Nguyen, Shaoguang Li, MD PhD, James E. Bradner, MD, Stuart H. Orkin, MD

Blood (2014) 124 (21): 778.

https://doi.org/10.1182/blood.V124.21.778.778

Published: 2014

Journal Articles

Genetic Depletion of Fc Gamma Receptor 2b Affects CML Stem Cell Biology

Oliver Herrmann, MSc, Caroline CA Weßling, MD, Michael Huber, PhD, Shaoguang Li, MD PhD, Tim H. Brümmendorf, MD, Steffen Koschmieder, MD, Mirle Schemionek, PhD

Blood (2014) 124 (21): 4528.

https://doi.org/10.1182/blood.V124.21.4528.4528

Published: 2014

Journal Articles

PKC Pathways Mediate BCR-ABL-Independent Imatinib Resistance in Chronic Myeloid Leukemia

Leyuan Ma, Yi Shan, Robert Bai, Liting Xue, Christopher A. Eide, Jianhong Ou, Lihua J. Zhu, Lloyd Hutchinson, PhD, Jan Cerny, MD PhD, H. Jean Khoury, MD, Zhi Sheng, Brian J. Druker, Shaoguang Li, MD PhD, Michael Green

Blood (2014) 124 (21): 1790.

https://doi.org/10.1182/blood.V124.21.1790.1790

Published: 2014

Journal Articles

Timing of the Loss of Pten Is Critical in Determining the Disease Phenotype in Mice- a Mouse Model for Pediatric Mixed MDS/MPN

Y. Lucy Liu, MD PhD, Yan Yan, MD, Cody Webster, BS, Lijian Shao, MD PhD, Shelly Y. Lensing, MS, Hongyu Ni, MD PhD, Wei Feng, MD, Daohong Zhou, MD, Zhifu Xiang, MD, Natalia Colorado, MD, Delli Robinson, Shaoguang Li, MD PhD, Peter D Emanuel, MD

Blood (2014) 124 (21): 3585.

https://doi.org/10.1182/blood.V124.21.3585.3585

Published: 2014

Journal Articles

Genetic and Pharmacologic Targeting Of Alox5 Attenuates JAK2V617F Induced PV In Mice

Yaoyu Chen, MD, PhD, Yi Shan, Zhiru Guo, PhD, Aibin Liang, MD, PhD, Shaoguang Li, MD, PhD

Blood (2013) 122 (21): 112.

https://doi.org/10.1182/blood.V122.21.112.112

Published: 2013

Journal Articles

Nfkb1 Plays a Tumor-Suppressing Role in BCR-ABL-Induced Leukemias

Con Sullivan, Yaoyu Chen, Zhiru Guo, Yi Shan, Cong Peng, Haojian Zhang, Jason Bubier, Thomas Sproule, Derry Roopenian, Shaoguang Li, MD, PhD

Blood (2012) 120 (21): 1666.

https://doi.org/10.1182/blood.V120.21.1666.1666

Published: 2012

Journal Articles

PRKD2 Serine-Threonine Kinase, an Essential Effector of Gabp Transcription Factor, Is Required for Development of Chronic Myelogenous Leukemia

Zhong-Fa Yang, PhD, Haojian Zhang, Leyuan Ma, Cong Peng, PhD, Yaoyu Chen, Michael Green, Shaoguang Li, MD, PhD, Alan G. Rosmarin, MD

Blood (2012) 120 (21): 1672.

https://doi.org/10.1182/blood.V120.21.1672.1672

Published: 2012

Journal Articles

Without GABP Transcription Factor, BCR-ABL Cannot Transform HSCs to Leukemic Stem Cells Nor Induce Chronic Myelogenous Leukemia in Mice

Zhongfa Yang, PhD, Cong Peng, Yaoyu Chen, Junling Wang, Xuejun Zhu, Karen Drumea, MD, Shaoguang Li, MD, PhD, Alan G. Rosmarin, MD

Blood (2011) 118 (21): 965.

https://doi.org/10.1182/blood.V118.21.965.965

Published: 2011

Journal Articles

HIF1α Is Required for Survival Maintenance of Chronic Myeloid Leukemia Stem Cells

Haojian Zhang, Huawei Li, Shaoguang Li, MD, PhD

Blood (2011) 118 (21): 449.

https://doi.org/10.1182/blood.V118.21.449.449

Published: 2011

Journal Articles

The Scd1 Gene Functions as a Tumor Suppressor In Leukemia Stem Cells

Haojian Zhang, Shaoguang Li, MD, PhD

Blood (2010) 116 (21): 201.

https://doi.org/10.1182/blood.V116.21.201.201

Published: 2010

Journal Articles

Loss of P-Selectin Promotes the Function of Aged Hematopoietic and Leukemic Stem Cells.

Yaoyu Chen, Sullivan Con, Yiguo Hu, Linghong Kong, Cong Peng, Shaoguang Li, MD, PhD

Blood (2010) 116 (21): 1577.

https://doi.org/10.1182/blood.V116.21.1577.1577

Published: 2010

Journal Articles

Distinct Gab2-Mediated Signaling Pathways Are Essential for Myeloid or Lymphoid Transformation and Leukemogenesis by BCR-ABL

M. Golam Mohi, PhD, Wayne W. Chan, BA, Shaoguang Li, MD, PhD, Benjamin Neel, MD, PhD, Richard A. Van Etten, MD, PhD

Blood (2008) 112 (11): 570.

https://doi.org/10.1182/blood.V112.11.570.570

Published: 2008

Journal Articles

DCC-2036: A Novel Switch Pocket Inhibitor of ABL Tyrosine Kinase with Therapeutic Efficacy Against BCR-ABL T315I In Vitro and in a CML Mouse Model.

Richard A. Van Etten, MD, PhD, Wayne W. Chan, BS, Virginia M. Zaleskas, MD, PhD, Peter Evangelista, BS, Katherine Lazarides, BS, Cong Peng, PhD, Shaoguang Li, MD, PhD, Scott C. Wise, PhD, Peter Petillo, PhD, Daniel L. Flynn, PhD

Blood (2007) 110 (11): 463.

https://doi.org/10.1182/blood.V110.11.463.463

Published: 2007

Journal Articles

Inhibitory Effects of Homoharringtonine on Leukemic Stem Cells and BCR-ABL Induced Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia in Mice.

Yaoyu Chen, MD, Yiguo Hu, MD., PhD, Shawnya Michaels, PhD, Dennis Brown, PhD, Shaoguang Li, MD, PhD

Blood (2007) 110 (11): 2912.

https://doi.org/10.1182/blood.V110.11.2912.2912

Published: 2007

Journal Articles

Curcumin Inhibits Proliferation of Leukemic Cells Expressing P210BCR-ABL or BCR-ABL-T315I and Prolongs Survival of Mice with B-Cell Acute Lymphoblastic Leukemia (B-ALL).

Basem M. William, MD, Ami Goodrich, Cong Peng, MS, Shaoguang Li, MD, PhD

Blood (2006) 108 (11): 1887.

https://doi.org/10.1182/blood.V108.11.1887.1887

Published: 2006

Journal Articles

Immunodominant Minor Histocompatibility Antigen-Specific T Lymphocytes Eradicate BCR-ABL-Induced B-ALL and CML without Causing Graft-Versus-Host Disease in Mice.

Yiguo Hu, MD, Thomas Sproule, BS, Cong Peng, MS, Linghong Kong, MD, PhD, Ami Goodrich, Derry Roopenian, PhD, Shaoguang Li, MD, PhD

Blood (2006) 108 (11): 3686.

https://doi.org/10.1182/blood.V108.11.3686.3686

Published: 2006

Journal Articles

Increase in Leukemic Stem Cells Is Associated with Acceleration of BCR-ABL-Induced CML in P-Selectin-Deficient Mice.

Linghong Kong, MD, PhD, Yiguo Hu, MD, Cong Peng, MS, Zhu Wang, Ted Duffy, PhD, Ami Goodrich, Shaoguang Li, MD, PhD

Blood (2006) 108 (11): 2129.

https://doi.org/10.1182/blood.V108.11.2129.2129

Published: 2006

NARROW

Bcr-Abl1 Kinase-Independent Upregulation of FcγRIIb Mediates Malignant Signaling That Is Critical for Leukemogenesis

Targeting Chronic Myeloid Leukemia Stem Cells through Pharmacological Inhibition of HIF-1α

Inhibition of CML Stem Cells with an Alkaloid That Reduces β-Catenin

Eradication of Chronic Myelogenous Leukemia By Inactivation of the Polycomb Group Protein EZH2

Genetic Depletion of Fc Gamma Receptor 2b Affects CML Stem Cell Biology

PKC Pathways Mediate BCR-ABL-Independent Imatinib Resistance in Chronic Myeloid Leukemia

Timing of the Loss of Pten Is Critical in Determining the Disease Phenotype in Mice- a Mouse Model for Pediatric Mixed MDS/MPN

Genetic and Pharmacologic Targeting Of Alox5 Attenuates JAK2V617F Induced PV In Mice

Nfkb1 Plays a Tumor-Suppressing Role in BCR-ABL-Induced Leukemias

PRKD2 Serine-Threonine Kinase, an Essential Effector of Gabp Transcription Factor, Is Required for Development of Chronic Myelogenous Leukemia

Without GABP Transcription Factor, BCR-ABL Cannot Transform HSCs to Leukemic Stem Cells Nor Induce Chronic Myelogenous Leukemia in Mice

HIF1α Is Required for Survival Maintenance of Chronic Myeloid Leukemia Stem Cells

The Scd1 Gene Functions as a Tumor Suppressor In Leukemia Stem Cells

Loss of P-Selectin Promotes the Function of Aged Hematopoietic and Leukemic Stem Cells.

Distinct Gab2-Mediated Signaling Pathways Are Essential for Myeloid or Lymphoid Transformation and Leukemogenesis by BCR-ABL

DCC-2036: A Novel Switch Pocket Inhibitor of ABL Tyrosine Kinase with Therapeutic Efficacy Against BCR-ABL T315I In Vitro and in a CML Mouse Model.

Inhibitory Effects of Homoharringtonine on Leukemic Stem Cells and BCR-ABL Induced Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia in Mice.

Curcumin Inhibits Proliferation of Leukemic Cells Expressing P210BCR-ABL or BCR-ABL-T315I and Prolongs Survival of Mice with B-Cell Acute Lymphoblastic Leukemia (B-ALL).

Immunodominant Minor Histocompatibility Antigen-Specific T Lymphocytes Eradicate BCR-ABL-Induced B-ALL and CML without Causing Graft-Versus-Host Disease in Mice.

Increase in Leukemic Stem Cells Is Associated with Acceleration of BCR-ABL-Induced CML in P-Selectin-Deficient Mice.

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American Society of Hematology

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American Society of Hematology

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