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Journal Articles

Sustained Growth of Primary Myeloma Cells in Coculture with Whole Donor Bone Marrow Is Associated with Induced Secretion of the Microenvironmental Mediator of Cytokinesis, Hemicentin-1

Rakesh Bam, PhD, Ricky D Edmondson, PhD, Caleb K Stein, MS, Xin Li, PhD, Wen Ling, MS, Sharmin Khan, MS, Randal S Shelton, B.S., Bart Barlogie, MD, PhD, Shmuel Yaccoby, PhD

Blood (2014) 124 (21): 3403.

https://doi.org/10.1182/blood.V124.21.3403.3403

Published: 2014

Journal Articles

ATRA Upregulates Cell Surface CD1D on Myeloma Cells and Sensitizes Them to iNKT Cell-Mediated Lysis

Xin Li, PhD, Tarun K. Garg, PhD, Sarah K. Johnson, PhD, Susann Szmania, BS, Justin Stivers, BS, Wen Ling, MS, Sharmin Khan, MS, Priyangi Malaviarachchi, Bart Barlogie, MD PhD, Frits van Rhee, MD PhD, Shmuel Yaccoby, PhD

Blood (2014) 124 (21): 2102.

https://doi.org/10.1182/blood.V124.21.2102.2102

Published: 2014

Journal Articles

Inhibition Of BTK Activity In Myeloma Cells Within a Supportive Microenvironment Promotes Their Growth But Suppresses Metastasis

Rakesh Bam, BS, Sathisha Upparahalli Venkateshaiah, Ph.D., Xin Li, PhD, Sharmin Khan, MS, Wen Ling, MS, Randal S Shelton, MS, Qing Zhang, PhD, Bart Barlogie, MD, PhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD

Blood (2013) 122 (21): 4432.

https://doi.org/10.1182/blood.V122.21.4432.4432

Published: 2013

Journal Articles

Healthy Donor Whole Bone Marrow Cells Preconditioned With Myeloma Patient Serum Support Long-Term Survival Of Primary Myeloma and Reveal Altered Microenvironmental Pathways

Rakesh Bam, BS, Sathisha Upparahalli Venkateshaiah, Ph.D., Xin Li, PhD, Sharmin Khan, MS, Wen Ling, MS, Randal S Shelton, MS, Joshua Epstein, DSc, Bart Barlogie, MD, PhD, Shmuel Yaccoby, PhD

Blood (2013) 122 (21): 3118.

https://doi.org/10.1182/blood.V122.21.3118.3118

Published: 2013

Journal Articles

GPRC5D Is a Cell Surface Plasma Cell Marker Whose Expression Is High In Myeloma Cells and Reduced Following Coculture With Osteoclasts

Sathisha Upparahalli venkateshaiah, PhD, Rakesh Bam, BS, Xin Li, PhD, Sharmin Khan, MS, Wen Ling, MS, Shelton Randal S, MS, Shmuel Yaccoby, PhD

Blood (2013) 122 (21): 3099.

https://doi.org/10.1182/blood.V122.21.3099.3099

Published: 2013

Journal Articles

HMOX1 Is a Targeted Therapy for Myeloma-Induced Bone Disease.

Xin Li, PhD, Wen Ling, MS, Sharmin Khan, MS, Sathisha Upparahalli Venkateshaiah, PhD, Rakesh Bam, Bart Barlogie, MD, PhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD

Blood (2012) 120 (21): 2944.

https://doi.org/10.1182/blood.V120.21.2944.2944

Published: 2012

Journal Articles

Reduced HMOX1 Expression in Myelomatous Bones Is Associated with Poor Survival and Its Induction Regulates Osteoclastogenesis and Osteoblastogenesis

Xin Li, PhD, Qing Zhang, PhD, Sarah K. Johnson, PhD, Wen Ling, MS, Sharmin Khan, MS, Frits van Rhee, MD, PhD, Saad Z Usmani, MD FACP, Sarah Waheed, MD, Bart Barlogie, MD, PhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD

Blood (2012) 120 (21): 1815.

https://doi.org/10.1182/blood.V120.21.1815.1815

Published: 2012

Journal Articles

Deregulated Cellular Iron Metabolism Factors Mediate Iron Overload in Myeloma Cells and Osteoclasts, and Promote Myeloma Growth and Bone Disease,

Rakesh Bam, Wen Ling, MS, Sharmin Khan, MS, Sathisha Upparahalli Venkateshaiah, PhD, Xin Li, PhD, Frits van Rhee, MD, PhD, Bijay Nair, MD, Saad Usmani, MD, FACP, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Joshua Epstein, DSc, Elias J. Anaissie, MD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 3941.

https://doi.org/10.1182/blood.V118.21.3941.3941

Published: 2011

Journal Articles

Stearoyl CoA Desaturase 1 (SCD1) Is Upregulated in Rapidly Growing Myeloma Cells and Is Required for Cell Proliferation,

Sathisha Upparahalli Venkateshaiah, PhD, Sharmin Khan, MS, Wen Ling, MS, Linda Saint John, Rakesh Bam, Xin Li, PhD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 3943.

https://doi.org/10.1182/blood.V118.21.3943.3943

Published: 2011

Journal Articles

Inducible Heme Oxygenase 1 (HMOX1) Promotes Osteoblastogenesis, and Inhibits Osteoclastogenesis and Myeloma-Induced Bone Disease

Xin Li, PhD, Sarah K. Johnson, PhD, Wen Ling, MS, Sharmin Khan, MS, Linda Saint John, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 627.

https://doi.org/10.1182/blood.V118.21.627.627

Published: 2011

Journal Articles

NAMPT/PBEF Enzymatic Activity Is Indispensable for Myeloma Cell Growth and Osteoclast Activity

Sathisha Upparahalli Venkateshaiah, PhD, Sharmin Khan, MS, Wen Ling, MS, Rakesh Bam, Xin Li, PhD, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 886.

https://doi.org/10.1182/blood.V118.21.886.886

Published: 2011

Journal Articles

Systemically Injected Mesenchymal Stem Cells Traffic to Myelomatous Bone and Inhibit Bone Disease, and Intralesionally Promotes Bone Formation and Delays Myeloma Progression During the Disease Active Stage or Remission

Xin Li, PhD, Wen Ling, MS, Sharmin Khan, MS, Yuping Wang, PhD, Angela Pennisi, MD, Bart Barlogie, MD, PhD, John Shaughnessy, Jr, PhD, Shmuel Yaccoby, PhD

Blood (2010) 116 (21): 980.

https://doi.org/10.1182/blood.V116.21.980.980

Published: 2010

Journal Articles

Human Placenta-Derived Adherent Cells Delivered Intralesionally Inhibit Myeloma Bone Disease and Tumor Growth, While Intravenously Are Capable of Trafficking to Myelomatous Bone.

Xin Li, PhD, Wen Ling, MS, Angela Pennisi, MD, Yuping Wang, PhD, Sharmin Khan, MS, Mohammad Heidaran, PhD, Ajai Pal, PhD, Xiaokui Zhang, PhD, Shuyang He, PhD, Andy Zeitlin, Stewart Abbot, PhD, Herbert Faleck, DO, Robert Hariri, MD, PhD., John Shaughnessy, Jr., PhD, Frits van Rhee, MD, PhD, Bijay Nair, MD, MPH, Bart Barlogie, MD, PhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD

Blood (2010) 116 (21): 3717.

https://doi.org/10.1182/blood.V116.21.3717.3717

Published: 2010

Journal Articles

Bruton's Tyrosine Kinase (BTK) Is Indispensable for Myeloma Cell Migration towards SDF-1 and Induction of Osteoclastogenesis and Osteolytic Bone Disease

Rakesh Bam, Angela Pennisi, MD, Xin Li, PhD, Sharmin Khan, MS, Yuping Wang, Ph.D., Wen Ling, MS, Bart Barlogie, M.D., Ph.D., John Shaughnessy, Jr., PhD, Shmuel Yaccoby, PhD

Blood (2010) 116 (21): 447.

https://doi.org/10.1182/blood.V116.21.447.447

Published: 2010

Journal Articles

Systemically Transplanted Human Bone Marrow Mesenchymal Stem Cells Primarily Traffic to Mesenteric Lymph Nodes

Xin Li, PhD, Wen Ling, MS, Sharmin Khan, MS, Yuping Wang, Ph.D., Angela Pennisi, MD, Bart Barlogie, MD, PhD, John Shaughnessy, Jr., PhD, Shmuel Yaccoby, PhD

Blood (2010) 116 (21): 2580.

https://doi.org/10.1182/blood.V116.21.2580.2580

Published: 2010

NARROW

Sustained Growth of Primary Myeloma Cells in Coculture with Whole Donor Bone Marrow Is Associated with Induced Secretion of the Microenvironmental Mediator of Cytokinesis, Hemicentin-1

ATRA Upregulates Cell Surface CD1D on Myeloma Cells and Sensitizes Them to iNKT Cell-Mediated Lysis

Inhibition Of BTK Activity In Myeloma Cells Within a Supportive Microenvironment Promotes Their Growth But Suppresses Metastasis

Healthy Donor Whole Bone Marrow Cells Preconditioned With Myeloma Patient Serum Support Long-Term Survival Of Primary Myeloma and Reveal Altered Microenvironmental Pathways

GPRC5D Is a Cell Surface Plasma Cell Marker Whose Expression Is High In Myeloma Cells and Reduced Following Coculture With Osteoclasts

HMOX1 Is a Targeted Therapy for Myeloma-Induced Bone Disease.

Reduced HMOX1 Expression in Myelomatous Bones Is Associated with Poor Survival and Its Induction Regulates Osteoclastogenesis and Osteoblastogenesis

Deregulated Cellular Iron Metabolism Factors Mediate Iron Overload in Myeloma Cells and Osteoclasts, and Promote Myeloma Growth and Bone Disease,

Stearoyl CoA Desaturase 1 (SCD1) Is Upregulated in Rapidly Growing Myeloma Cells and Is Required for Cell Proliferation,

Inducible Heme Oxygenase 1 (HMOX1) Promotes Osteoblastogenesis, and Inhibits Osteoclastogenesis and Myeloma-Induced Bone Disease

NAMPT/PBEF Enzymatic Activity Is Indispensable for Myeloma Cell Growth and Osteoclast Activity

Systemically Injected Mesenchymal Stem Cells Traffic to Myelomatous Bone and Inhibit Bone Disease, and Intralesionally Promotes Bone Formation and Delays Myeloma Progression During the Disease Active Stage or Remission

Human Placenta-Derived Adherent Cells Delivered Intralesionally Inhibit Myeloma Bone Disease and Tumor Growth, While Intravenously Are Capable of Trafficking to Myelomatous Bone.

Bruton's Tyrosine Kinase (BTK) Is Indispensable for Myeloma Cell Migration towards SDF-1 and Induction of Osteoclastogenesis and Osteolytic Bone Disease

Systemically Transplanted Human Bone Marrow Mesenchymal Stem Cells Primarily Traffic to Mesenteric Lymph Nodes

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American Society of Hematology

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