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Journal Articles

The T117S Variant of Cytochrome b5 Reductase 3 Increases the Risk for Ischemic Stroke with Enhanced Anemia in Mice with Sickle Cell Disease

Katherine C Wood, PhD, Heidi M Schmidt, Scott Hahn, MS, Subramaniam Sanker, PhD, Samit Ghosh, PhD, Solomon Fiifi Ofori-Acquah, PhD, Seyed Mehdi Nouraie, MD PhD, Mark T Gladwin, MD, Adam C Straub, PhD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-142076

Published: 2020

Journal Articles

Nonhematopoietic Nrf2 Deficiency Worsens Chronic Intravascular Hemolysis but Not Cardiomyopathy in Transgenic Sickle Cell Mice

Maureen Mburu, Samit Ghosh, PhD, Xucai Chen, PhD, Solomon Fiifi Ofori-Acquah, PhD, Flordeliza S Villanueva, MD

Blood (2020) 136 (Supplement 1): 18.

https://doi.org/10.1182/blood-2020-142783

Published: 2020

Journal Articles

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Samit Ghosh, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2018) 132 (Supplement 1): 2392.

https://doi.org/10.1182/blood-2018-99-113451

Published: 2018

Journal Articles

Enhanced Renal Clearance of Heme Triggers Acute Kidney Injury in Sickle Cell Disease

Samit Ghosh, PhD, Vivian Paintsil, MD, Rimi Hazra, PhD, Oluowaseun O. Orikogbo, Bethany Flage, Ezekiel Bonwin Ackah, Ellis Owusu-Dabo, PhD, Solomon Fiifi Ofori-Acquah, PhD

Blood (2017) 130 (Supplement 1): 441.

https://doi.org/10.1182/blood.V130.Suppl_1.441.441

Published: 2017

Journal Articles

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Maria G Kapetanaki, PhD, Oluwabukola Gbotosho, BSc, MSc, PhD, Deva Sharma, MD MS, Schrott Valerie, MS, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Grant C. Bullock, MD PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3496.

https://doi.org/10.1182/blood.V130.Suppl_1.3496.3496

Published: 2017

Journal Articles

Cardiomyopathy Associated with Worsening Intravascular Hemolysis in Transgenic Knock-in Mouse Model of Sickle Cell Disease

Maureen Mburu, MD, Rafey Feroze, BS, Daniel Whitehurst, BS, Xucai Chen, PhD, Samit Ghosh, PhD, Solomon Fiifi Ofori-Acquah, PhD, Flordeliza S Villanueva, MD

Blood (2017) 130 (Supplement 1): 3512.

https://doi.org/10.1182/blood.V130.Suppl_1.3512.3512

Published: 2017

Journal Articles

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3468.

https://doi.org/10.1182/blood.V130.Suppl_1.3468.3468

Published: 2017

Journal Articles

Moderate Exercise Training Attenuates Inflammation in Transgenic Sickle Cell Mice

Emmanuelle Charrin, Cyril Martin, PhD, John Dube, PhD, Philippe Connes, PhD, Vincent Pialoux, PhD, Solomon Fiifi Ofori-Acquah, PhD

Blood (2015) 126 (23): 976.

https://doi.org/10.1182/blood.V126.23.976.976

Published: 2015

Journal Articles

The Oxidant Response Transcription Factor NRF2 Mediates Heme Activation of Placenta Growth Factor Expression in Erythroid Cells, a Contributor to Pulmonary Hypertension in Sickle Cell Disease

Maria G Kapetanaki, PhD, Deva Sharma, MD MS, Oluwabukola T Gbotosho, PhD, Valerie Schrott, MS, Frances Weidart, BS, Solomon Fiifi Ofori-Acquah, PhD, Grant C Bullock, MD PhD, Gregory J. Kato, MD

Blood (2015) 126 (23): 403.

https://doi.org/10.1182/blood.V126.23.403.403

Published: 2015

Journal Articles

Prophylactic Nrf2 Activation Halts Progression of the Severe Adult Phenotype of Sickle Cell Disease in Transgenic Mice

Samit Ghosh, PhD, Chibueze A. Ihunnah, PhD, Rimi Hazra, PhD, Amma T. Owusu-Ansah, MD, Jason M Hansen, PhD, David R. Archer, PhD, Solomon Fiifi Ofori-Acquah, PhD

Blood (2015) 126 (23): 3394.

https://doi.org/10.1182/blood.V126.23.3394.3394

Published: 2015

Journal Articles

Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease

Yongzhi Qiu, PhD, Byungwook Ahn, PhD, Yumiko Sakurai, MSc, Caroline Hansen, BS, Clinton H. Joiner, MD PhD, Solomon Fiifi Ofori-Acquah, PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 240.

https://doi.org/10.1182/blood.V126.23.240.240

Published: 2015

Journal Articles

Dissection of the Expression Patterns of Hydroxyurea Transporters during Erythropoiesis and Myelopoiesis

Aisha L Walker, PhD, Solomon Fiifi Ofori-Acquah, PhD

Blood (2015) 126 (23): 3395.

https://doi.org/10.1182/blood.V126.23.3395.3395

Published: 2015

Journal Articles

Prevalence of Relative Systemic Hypertension in Ghanaian Adults with Sickle Cell Disease

Amma A. Benneh, MD, Amma T. Owusu-Ansah, MD, Fredericka Sey, MB ChB, Mary A. Ampomah, BSc Psychology, MPhil Clinical Psychology, Edeghonghon Olayemi, MBBS, MSc, FWACP, Solomon Fiifi Ofori-Acquah, PhD

Blood (2015) 126 (23): 3409.

https://doi.org/10.1182/blood.V126.23.3409.3409

Published: 2015

Journal Articles

Evidence for Quantitative and Functional Immune Deviation in Pediatric Patients with Sickle Cell Disease

Leslie Kean, MD, PHD, Sharon Sen, Martha Ann Felder, CRA, VIN Tangpricha, MD, PHD, Olufolake Adisa, MD, Angelica JAMES-Herry, MD, Iris Buchanan, MD, MSC, Thomas Ziegler, Jessica Alvarez, RD, PhD, Jonathan Beus, Diana Worthington-White, RN, CRA, Jennifer Robertson, PhD, Jackie George, BS, Joshua Cetron, Solomon Fiifi Ofori-Acquah, PhD, Ifeyinwa Osunkwo, MD, MPH

Blood (2011) 118 (21): 1054.

https://doi.org/10.1182/blood.V118.21.1054.1054

Published: 2011

Journal Articles

Dominant Role for SDF-1 in the Vasculo-Angiogenesis Phenotype in Children with Sickle Cell Disease.

Beatrice E Gee, M.D., Jerry M Manlove-Simmons, B.S, Yao Huang, M.S., Nana Wilson, B.S., Jonathan Stiles, Ph.D., Solomon Fiifi Ofori-Acquah, PhD

Blood (2008) 112 (11): 1432.

https://doi.org/10.1182/blood.V112.11.1432.1432

Published: 2008

NARROW

The T117S Variant of Cytochrome b5 Reductase 3 Increases the Risk for Ischemic Stroke with Enhanced Anemia in Mice with Sickle Cell Disease

Nonhematopoietic Nrf2 Deficiency Worsens Chronic Intravascular Hemolysis but Not Cardiomyopathy in Transgenic Sickle Cell Mice

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Enhanced Renal Clearance of Heme Triggers Acute Kidney Injury in Sickle Cell Disease

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Cardiomyopathy Associated with Worsening Intravascular Hemolysis in Transgenic Knock-in Mouse Model of Sickle Cell Disease

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Moderate Exercise Training Attenuates Inflammation in Transgenic Sickle Cell Mice

The Oxidant Response Transcription Factor NRF2 Mediates Heme Activation of Placenta Growth Factor Expression in Erythroid Cells, a Contributor to Pulmonary Hypertension in Sickle Cell Disease

Prophylactic Nrf2 Activation Halts Progression of the Severe Adult Phenotype of Sickle Cell Disease in Transgenic Mice

Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease

Dissection of the Expression Patterns of Hydroxyurea Transporters during Erythropoiesis and Myelopoiesis

Prevalence of Relative Systemic Hypertension in Ghanaian Adults with Sickle Cell Disease

Evidence for Quantitative and Functional Immune Deviation in Pediatric Patients with Sickle Cell Disease

Dominant Role for SDF-1 in the Vasculo-Angiogenesis Phenotype in Children with Sickle Cell Disease.

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American Society of Hematology

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American Society of Hematology

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