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Stefan Karlsson, MD/PhD
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Journal Articles

Glucocorticoids Reduce Expression Of p53 Target Genes and Reverse Anemia In a Mouse Model Of Diamond-Blackfan Anemia

Sara Sjögren, Pekka Jaako, PhD, Stefan Karlsson, MD, PhD, Johan Flygare, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3703.
https://doi.org/10.1182/blood.V122.21.3703.3703
Published: 2013
Journal Articles

A Critical Role for BMP Signaling in Adult Hematopoietic Stem Cells

Ulrika Blank, PhD, Sarah Warsi, Silja Andradottir, Emma Rörby, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1194.
https://doi.org/10.1182/blood.V120.21.1194.1194
Published: 2012
Journal Articles

Developmental Pluripotency Associated 5 (Dppa5) Regulates Hematopoietic Stem Cell Reconstitution Capacity by Modulating Cellular Metabolism and ER Stress

Kenichi Miharada, PhD, Valgardur Sigurdsson, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 847.
https://doi.org/10.1182/blood.V120.21.847.847
Published: 2012
Journal Articles

Gene Therapy Corrects the Lethal Bone Marrow Failure in a Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia

Pekka Jaako, Shubhranshu Debnath, Karin Olsson, Axel Schambach, MD, PhD, Christopher Baum, MD, Johan Flygare, MD, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 513.
https://doi.org/10.1182/blood.V120.21.513.513
Published: 2012
Journal Articles

Diamond-Blackfan Anemia: Erythropoiesis Lost in Ribosome Biosynthesis

Stefan Karlsson, MD, PhD, Johan Flygare, Pekka Jaako, MS, David Bryder, PhD
Journal: Blood
Blood (2011) 118 (21): SCI-2.
https://doi.org/10.1182/blood.V118.21.SCI-2.SCI-2
Published: 2011
Journal Articles

Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond-Blackfan Anemia

Pekka Jaako, Johan Flygare, MD, PhD, Karin Olsson, Ronan Quere, PhD, Jonas Larsson, MD, PhD, David Bryder, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 193.
https://doi.org/10.1182/blood.V116.21.193.193
Published: 2010
Journal Articles

Cripto Selectively Expands a Distinct Population of Hematopoietic Stem Cells Expressing the Cell Surface Receptor GRP78 and Strongly Induces An Immature Phenotype In Vivo After Ex Vivo Culture

Kenichi Miharada, PhD, Göran Karlsson, PhD, Jonas Larsson, MD, PhD, Emma Larsson, Kavitha Siva, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 405.
https://doi.org/10.1182/blood.V116.21.405.405
Published: 2010
Journal Articles

SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation

Ronan Quere, PhD, Göran Karlsson, PhD, Falk Hertwig, Marianne Rissler, Beata Lindqvist, Thoas Fioretos, MD, PhD, Peter Vandenberghe, MD, PhD, Marilyn L. Slovak, PhD, Kristian Reckzeh, Jörg Cammenga, MD, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3153.
https://doi.org/10.1182/blood.V116.21.3153.3153
Published: 2010
Journal Articles

High Levels of the Adhesion Molecule CD44 on Leukemic Cells Generate Acute Myeloid Leukemia Relapse After Withdrawal of the Initial Transforming Event

Ronan Quere, PhD, Silja Andradottir, Ann Brun, PhD, Roman Zubarev, PhD, Göran Karlsson, PhD, Karin Olsson, Mattias Magnusson, PhD, Jörg Cammenga, MD, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3154.
https://doi.org/10.1182/blood.V116.21.3154.3154
Published: 2010
Journal Articles

Defective Ribosomal RNA Maturation in Patients with Diamond Blackfan Anemia.

Paola Quarello, MD, Anna Aspesi, Johan Flygare, Stefan Karlsson, MD/PhD, Steven R. Ellis, PhD
Journal: Blood
Blood (2006) 108 (11): 4172.
https://doi.org/10.1182/blood.V108.11.4172.4172
Published: 2006
Journal Articles

Deficient Ribosomal Protein S19 in Diamond-Blackfan Anemia Causes a Reduction in bcl-2 and Bad and Leads to Apoptosis in Erythroid Progenitor Cells.

Koichi Miyake, MD, PhD, Taiju Utsugisawa, MD, PhD, Johan Flygare, Thomas Kiefer, MD, Isao Hamaguchi, MD, PhD, Johan Richter, MD, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 131.
https://doi.org/10.1182/blood.V106.11.131.131
Published: 2005
Journal Articles

Apoptotic Change Is a Major Reason for Defect in Early Erythroid Development in Cell Line Models for Ribosomal Protein (RP) S19 Deficient Diamond-Blackfan Anemia.

Koichi Miyake, MD, PhD, Taiju Utsugisawa, MD, PhD, Johan Flygare, Thomas Kiefer, MD, Johan Richter, MD, PhD, Maciej Wiznerowicz, MD, PhD, Didier Trono, MD, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 2840.
https://doi.org/10.1182/blood.V104.11.2840.2840
Published: 2004
Journal Articles

HOXA10 Affects the Fate of Hematopoietic Progenitors and Stem Cells in a Concentration Dependent Manner.

Ann C.M. Brun, PhD, Mattias Magnusson, MS, Noriko Miyake, BS, Eva Nilsson, Jon Mar Björnsson3, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3550.
https://doi.org/10.1182/blood.V104.11.3550.3550
Published: 2004
Journal Articles

Isolation and Characterization of Living Cord Blood CD34+ Cells with Telomerase Reverse Transcriptase (TERT) Expression.

Marcus Nilsson-Jaras, MSc, Anna Edqvist, Msc, Johan Rebetz, MSc, Bengt Widegren, PhD, Stefan Karlsson, MD, PhD, Xiaolong Fan, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3559.
https://doi.org/10.1182/blood.V104.11.3559.3559
Published: 2004
Journal Articles

Hematopoietic Stem Cell Expansion by HOXB4 Is Greatly Enhanced in p21 Deficient Stem Cells.

Noriko Miyake, BS, Ann C.M. Brun, PhD, Mattias Magnusson, MS, David T. Scadden, MD, PhD, Stefan Karlsson, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 1688.
https://doi.org/10.1182/blood.V104.11.1688.1688
Published: 2004