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Journal Articles

Serum IgM/Fcmr Interactions Inhibit BCR Signaling and Influence the Cinical Course of CLL

Stefania Gobessi, PhD, Luca Laurenti, MD, Fabiola Porro, MS, Claudio Martines, MS, Rosa Fazio, BS, Elena Xerxa, PhD, Idanna Innocenti, MD PhD, Antonella Zucchetto, Shih-Shih Chen, PhD, Xiao-Jie Yan, MD PhD, Nicholas Chiorazzi, MD, Valter Gattei, MD, Dimitar G Efremov, MD PhD

Blood (2018) 132 (Supplement 1): 4409.

https://doi.org/10.1182/blood-2018-99-118562

Published: 2018

Journal Articles

Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities

Tiziana Vaisitti, PhD, Sara Serra, PhD, Cinzia Bologna, PhD, Nicoletta Vitale, PhD, Stefania Gobessi, PhD BS, Dimitar G Efremov, MD PhD, Silvia Deaglio, MD

Blood (2017) 130 (Supplement 1): 1721.

https://doi.org/10.1182/blood.V130.Suppl_1.1721.1721

Published: 2017

Journal Articles

The Bcl-2 BH4 Antagonist Bda-366 Induces Apoptosis in CLL and DLBCL Cells through a Bcl-2 Independent Mechanism

Binu K Sasi, PhD, Tamara Vervloessem, PhD, Stefania Gobessi, PhD, Idanna Innocenti, MD, Luca Laurenti, Geert Bultynck, PhD, Dimitar G Efremov, MD PhD

Blood (2016) 128 (22): 2014.

https://doi.org/10.1182/blood.V128.22.2014.2014

Published: 2016

Journal Articles

FcμR Triggering Activates BCR Signaling Pathways and Increases Survival of CLL Cells

Stefania Gobessi, PhD, Binu K Sasi, PhD, Gabriele Pozzato, MD, Idanna Innocenti, MD, Luca Laurenti, Dimitar G Efremov, MD PhD

Blood (2016) 128 (22): 2015.

https://doi.org/10.1182/blood.V128.22.2015.2015

Published: 2016

Journal Articles

Serum IgM Activates BCR Signaling Pathways and Increases Survival of Chronic Lymphocytic Leukemia B Cells

Stefania Gobessi, PhD, Binu K Sasi, PhD, Luca Laurenti, MD, Dimitar G Efremov, MD PhD

Blood (2015) 126 (23): 4131.

https://doi.org/10.1182/blood.V126.23.4131.4131

Published: 2015

Journal Articles

Inhibition of SYK More Effectively Overcomes MCL-1 Mediated ABT-199 Resistance of BCR-Stimulated CLL Cells Than Inhibition of BTK or PI3Kdelta

Kamil Bojarczuk, PhD, Binu K Sasi, PhD, Stefania Gobessi, PhD, Idanna Innocenti, MD, Luca Laurenti, MD, Dimitar G Efremov, MD PhD

Blood (2015) 126 (23): 489.

https://doi.org/10.1182/blood.V126.23.489.489

Published: 2015

Journal Articles

The Nature of the Antigen Determines Leukemia Development and Behavior in the Eμ-TCL1 Transgenic Mouse Model of CLL

Sara Bennardo, BS, Stefano Iacovelli, BS, Stefania Gobessi, PhD, Mirza Suljagic, DVM, PhD, Daniel Bilbao, PhD, Julia Eckl-Dorna, MD, PhD, Hongsheng Wang, MD, PhD, Richard J. Cornall, MD, PhD, Stephen H Clarke, PhD, Carlo M. Croce, MD, Dimitar G Efremov, MD, PhD

Blood (2012) 120 (21): 181.

https://doi.org/10.1182/blood.V120.21.181.181

Published: 2012

Journal Articles

Expression of ZAP-70 Does Not Accelerate Leukemia Development and Progression in the Eμ-TCL1 Transgenic Mouse Model of Chronic Lymphocytic Leukemia

Stefania Gobessi, PhD, Francesca Belfiore, PhD, Sara Bennardo, BS, Brendan Doe, BS, Luca Laurenti, MD, Dimitar G Efremov, MD, PhD

Blood (2012) 120 (21): 925.

https://doi.org/10.1182/blood.V120.21.925.925

Published: 2012

Journal Articles

Development of a Transgenic Mouse Model to Study the Role of ZAP-70 in the Development and Progression of Chronic Lymphocytic Leukemia

Stefania Gobessi, PhD, Sara Bennardo, BS, Pablo G Longo, MD, Brendan Doe, BS, Dimitar G Efremov, MD, PhD

Blood (2011) 118 (21): 2830.

https://doi.org/10.1182/blood.V118.21.2830.2830

Published: 2011

Journal Articles

Overexpression of the Autoimmunity-Associated Tyrosine Phosphatase PTPN22 in CLL Cells Enhances Antiapoptotic B-Cell Receptor Signals Through Selective Activation of the AKT Pathway

Roberto Negro, PhD, Stefania Gobessi, PhD, Pablo G Longo, MD, Luca Laurenti, Dimitar G Efremov, MD, PhD

Blood (2011) 118 (21): 619.

https://doi.org/10.1182/blood.V118.21.619.619

Published: 2011

Journal Articles

Overexpression of the Protein Tyrosine Phosphatase Lyp Reduces the Responsiveness of Chronic Lymphocytic Leukemia B-Cells to B-Cell Receptor Ligation.

Roberto Negro, PhD, Pablo G Longo, MD, Michela Tarnani, MD, Stefania Gobessi, PhD, Luca Laurenti, MD, Dimitar G Efremov, MD, PhD

Blood (2009) 114 (22): 800.

https://doi.org/10.1182/blood.V114.22.800.800

Published: 2009

Journal Articles

Molecular Requirements for Syk-Mediated Intracellular Signaling and B-Cell Transformation

Laura Carsetti, BS, Luca Laurenti, MD, Stefania Gobessi, PhD, Pablo G Longo, MD, Giuseppe Leone, MD, Dimitar G Efremov, MD, PhD

Blood (2008) 112 (11): 2837.

https://doi.org/10.1182/blood.V112.11.2837.2837

Published: 2008

Journal Articles

The Akt/Mcl-1 Pathway Plays a Prominent Role in Mediating Pro-Survival Signals Derived from the B-Cell Receptor in Chronic Lymphocytic Leukemia B-Cells.

Pablo G. Longo, MD, Luca Laurenti, MD, Stefania Gobessi, PhD, Simona Sica, MD, Giuseppe Leone, MD, Dimitar G. Efremov, MD, PhD

Blood (2007) 110 (11): 341.

https://doi.org/10.1182/blood.V110.11.341.341

Published: 2007

Journal Articles

The Proliferative Response to CpG ODN Stimulation Predicts Disease Progression in B-Cell Chronic Lymphocytic Leukemia.

Luca Laurenti, MD, Pablo G. Longo, MD, Michela Tarnani, MD, Stefania Gobessi, PhD, Simona Sica, MD, Giuseppe Leone, MD, Dimitar G. Efremov, MD, PhD

Blood (2007) 110 (11): 3098.

https://doi.org/10.1182/blood.V110.11.3098.3098

Published: 2007

Journal Articles

Constitutive Activation of the Protein Tyrosine Kinase Syk in Chronic Lymphocytic Leukemia B-Cells.

Stefania Gobessi, PhD, Luca Laurenti, MD, Pablo Longo, MD, Laura Carsetti, BS, Simona Sica, MD, Giuseppe Leone, MD, Dimitar G. Efremov, MD, PhD

Blood (2007) 110 (11): 1123.

https://doi.org/10.1182/blood.V110.11.1123.1123

Published: 2007

Journal Articles

Introduction of Constitutivelly Active Akt in Primary CLL B-Cells Results in Upregulation of Mcl-1, Bcl-XL and Cyclin D3 and Promotes Leukemic Cell Survival.

Pablo Longo, MD, Stefania Gobessi, PhD, Luca Laurenti, MD, Simona Sica, MD, Giuseppe Leone, MD, Dimitar G. Efremov, MD, PhD

Blood (2006) 108 (11): 2805.

https://doi.org/10.1182/blood.V108.11.2805.2805

Published: 2006

Journal Articles

ZAP-70 Is Not Phosphorylated on the Activating Tyrosine Residue (Tyr 319 ) in Chronic Lymphocytic Leukemia and B-Cell Lymphoma Cells.

Stefania Gobessi, PhD, Aleksandar Petlickovski, MD, Luca Laurenti, MD, Dimitar G. Efremov, MD, PhD

Blood (2005) 106 (11): 178.

https://doi.org/10.1182/blood.V106.11.178.178

Published: 2005

Journal Articles

Immunostimulatory CpG Oligodeoxynucleotides Induce Sustained ERK2 Activation and Strong Proliferative Responses in CLL B-Cells from Patients with Progressive Disease.

Aleksandar Petlickovski, MD, Luca Laurenti, MD, Stefania Gobessi, PhD, Simona Sica, MD, Giuseppe Leone, MD, Dimitar, G. Efremov, MD, PhD

Blood (2005) 106 (11): 1180.

https://doi.org/10.1182/blood.V106.11.1180.1180

Published: 2005

NARROW

Serum IgM/Fcmr Interactions Inhibit BCR Signaling and Influence the Cinical Course of CLL

Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities

The Bcl-2 BH4 Antagonist Bda-366 Induces Apoptosis in CLL and DLBCL Cells through a Bcl-2 Independent Mechanism

FcμR Triggering Activates BCR Signaling Pathways and Increases Survival of CLL Cells

Serum IgM Activates BCR Signaling Pathways and Increases Survival of Chronic Lymphocytic Leukemia B Cells

Inhibition of SYK More Effectively Overcomes MCL-1 Mediated ABT-199 Resistance of BCR-Stimulated CLL Cells Than Inhibition of BTK or PI3Kdelta

The Nature of the Antigen Determines Leukemia Development and Behavior in the Eμ-TCL1 Transgenic Mouse Model of CLL

Expression of ZAP-70 Does Not Accelerate Leukemia Development and Progression in the Eμ-TCL1 Transgenic Mouse Model of Chronic Lymphocytic Leukemia

Development of a Transgenic Mouse Model to Study the Role of ZAP-70 in the Development and Progression of Chronic Lymphocytic Leukemia

Overexpression of the Autoimmunity-Associated Tyrosine Phosphatase PTPN22 in CLL Cells Enhances Antiapoptotic B-Cell Receptor Signals Through Selective Activation of the AKT Pathway

Overexpression of the Protein Tyrosine Phosphatase Lyp Reduces the Responsiveness of Chronic Lymphocytic Leukemia B-Cells to B-Cell Receptor Ligation.

Molecular Requirements for Syk-Mediated Intracellular Signaling and B-Cell Transformation

The Akt/Mcl-1 Pathway Plays a Prominent Role in Mediating Pro-Survival Signals Derived from the B-Cell Receptor in Chronic Lymphocytic Leukemia B-Cells.

The Proliferative Response to CpG ODN Stimulation Predicts Disease Progression in B-Cell Chronic Lymphocytic Leukemia.

Constitutive Activation of the Protein Tyrosine Kinase Syk in Chronic Lymphocytic Leukemia B-Cells.

Introduction of Constitutivelly Active Akt in Primary CLL B-Cells Results in Upregulation of Mcl-1, Bcl-XL and Cyclin D3 and Promotes Leukemic Cell Survival.

ZAP-70 Is Not Phosphorylated on the Activating Tyrosine Residue (Tyr 319 ) in Chronic Lymphocytic Leukemia and B-Cell Lymphoma Cells.

Immunostimulatory CpG Oligodeoxynucleotides Induce Sustained ERK2 Activation and Strong Proliferative Responses in CLL B-Cells from Patients with Progressive Disease.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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