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Journal Articles

Improved Outcomes of Budd-Chiari Syndrome in Paroxysmal Nocturnal Hemoglobinuria with Eculizumab Therapy

Joanna Haughton, MBChB, Richard J Kelly, MBChB, Stephen J Richards, PhD, Louise M Arnold, RN, BSc, Alexandra Wood, RN, BSc, Tracy Downing, Claire McKinley, BSc, Mervyn Davies, MBChB, Peter Hillmen, MBChB, PhD, Anita Hill, MBChB, PhD

Blood (2012) 120 (21): 3478.

https://doi.org/10.1182/blood.V120.21.3478.3478

Published: 2012

Journal Articles

Successful Pregnancy Outcomes in Paroxysmal Nocturnal Hemoglobinuria with Long-Term Eculizumab Treatment

Richard Kelly, MD, Louise Arnold, BSc, MA, Stephen J. Richards, PhD, Anita Hill, MD, Charlotte Bomken, MD, John Hanley, MD, Andrew Loughney, MD, PhD, Gus Khursigara, PhD, Russell P. Rother, PhD, Elizabeth Chalmers, MD, Edward Fitzsimons, MD, Ryotaro Nakamura, MD, Anna Gaya, MD, Bruno Rotoli, MD, Antonio M. Risitano, MD, PhD, Joerg Schubert, MD, Peter Hillmen, MB, PhD

Blood (2008) 112 (11): 4576.

https://doi.org/10.1182/blood.V112.11.4576.4576

Published: 2008

Journal Articles

Eculizumab Reduces Pulmonary Hypertension through Inhibition of Hemolysis-Associated Nitric Oxide Consumption in Patients with Paroxysmal Nocturnal Hemoglobinuria

Anita Hill, MD, Russell P. Rother, PhD, Xunde Wang, MD, Robert J Sapsford, MD, Paul O Collinson, MD, David C Gaze, PhD, Sidney M Morris, Jr., PhD, Andrew Scally, Kerry Quinn-Senger, PhD, Stephen J Richards, PhD, Monica Bessler, MD, PhD, Richard Kelly, MD, Peter Hillmen, MBChB, PhD, Mark Gladwin, MD

Blood (2008) 112 (11): 486.

https://doi.org/10.1182/blood.V112.11.486.486

Published: 2008

Journal Articles

The Investigation of HMGA2 Dysregulation and Promoter Mutations in PIG-M in the Molecular Pathogenesis of Paroxysmal Nocturnal Haemoglobinuria (PNH).

Richard J. Kelly, MD, Reuben M. Tooze, PhD, Gina M. Doody, PhD, Stephen J. Richards, PhD, Peter Hillmen, PhD

Blood (2007) 110 (11): 3671.

https://doi.org/10.1182/blood.V110.11.3671.3671

Published: 2007

Journal Articles

Abortive Plasma Cell Differentiation with Loss of Mature B-Cell Phenotype in a Subset of Patients with De Novo Diffuse Large B-Cell Lymphoma and Transformed Follicular Lymphoma: Relevance of cMYC Rearrangements.

Matthew J. Cullen, MSc, Sharon L. Barrans, PhD, Stephen J. Richards, PhD, Andy C. Rawstron, PhD, Sheila J.M. O’Connor, PhD, Reuben M. Tooze, PhD, Roger G. Owen, MD, Andrew Jack, MD

Blood (2006) 108 (11): 4643.

https://doi.org/10.1182/blood.V108.11.4643.4643

Published: 2006

Journal Articles

The Incidence and Prevalence of Paroxysmal Nocturnal Hemoglobinuria (PNH) and Survival of Patients in Yorkshire.

Anita Hill, MD, Philip J. Platts, MRes, Alex Smith, PhD, Stephen J. Richards, PhD, Matthew J. Cullen, MSc, Quentin A. Hill, MD, Eve Roman, PhD, Peter Hillmen, PhD

Blood (2006) 108 (11): 985.

https://doi.org/10.1182/blood.V108.11.985.985

Published: 2006

Journal Articles

Blockade of Intravascular Hemolysis in PNH with the Terminal Complement Inhibitor Eculizumab Unmasks Low-Level Hemolysis Potentially Occurring through C3 Opsonization.

Anita Hill, MD, Russell P. Rother, PhD, Antonio M. Risitano, PhD, Duncan S. Cole, PhD, Matthew J. Cullen, MSc, Stephen J. Richards, PhD, Carmine Selleri, MD, Patrizia Ricci, BSc, Bruno Rotoli, MD, Lucio Luzzatto, PhD, Peter Hillmen, PhD

Blood (2006) 108 (11): 972.

https://doi.org/10.1182/blood.V108.11.972.972

Published: 2006

Journal Articles

Nitric Oxide Consumption and Pulmonary Hypertension in Patients with Paroxysmal Nocturnal Hemoglobinuria.

Anita Hill, MD, Xunde Wang, PhD, Robert J. Sapsford, MD, Rother P. Russell, PhD, Alison L. Farrell, PGDip, Hilary A. Jessop, Gina M. McGawley, MSc, David L. Oxborough, BHSc, Paul Pleasants, BSc, Stephen J. Richards, PhD, Louise M. Arnold, BSc, David M. Buchanan, MA, Sara Rollinson, PhD, Mark T. Gladwin, MD, Peter Hillmen, PhD

Blood (2005) 106 (11): 1046.

https://doi.org/10.1182/blood.V106.11.1046.1046

Published: 2005

Journal Articles

The Effect of Eculizumab Therapy on Red Cell Response Kinetics in Patients with Paroxysmal Nocturnal Hemoglobinuria.

Stephen J. Richards, PhD, Matthew J. Cullen, MSc, Anita J. Dickinson, MSc, Anita Hill, MD, David Buchanon, MA, Louise Arnold, BSc, Modupe Elebute, MD, Russell P. Rother, PhD, Peter Hillmen, PhD

Blood (2005) 106 (11): 1047.

https://doi.org/10.1182/blood.V106.11.1047.1047

Published: 2005

Journal Articles

IgH Rearrangements and Mutational Status in Class-Switched IgG B-CLL.

James A.L. Fenton, DPhil, David Gonzalez, PhD, Andy C. Rawstron, PhD, Gareth J. Morgan, MS, BCh, PhD, Andrew S. Jack, MB ChB PhD, Stephen J. Richards, PhD, Peter Hillmen, MB ChB PhD

Blood (2004) 104 (11): 2793.

https://doi.org/10.1182/blood.V104.11.2793.2793

Published: 2004

Journal Articles

Sustained Control of Hemolysis and Symptoms and Reduced Transfusion Requirements over a Period of 2 Years in Paroxysmal Nocturnal Hemoglobinuria (PNH) with Eculizumab Therapy.

Anita Hill, MD, Dupe Elebute, MD, Judith C. Marsh, MD, Stephen J. Richards, PhD, Bruce McNutt, MD, Beth E. Petro, BS, Russell P. Rother, PhD, Peter Hillmen, PhD

Blood (2004) 104 (11): 2823.

https://doi.org/10.1182/blood.V104.11.2823.2823

Published: 2004

Journal Articles

Evolution of GPI-Deficient Clones Predicts Clinical Course in Paroxysmal Nocturnal Haemoglobinuria.

Stephen J. Richards, PhD, Matthew J. Cullen, MSc, Anita J. Dickinson, MSc, Claire Hall, MD, Anita Hill, MD, Peter Hillmen, PhD

Blood (2004) 104 (11): 172.

https://doi.org/10.1182/blood.V104.11.172.172

Published: 2004

Journal Articles

Differential Clearance Kinetics and Phenotypic Alterations of Leukaemic Blast Cells during Induction Therapy for Hyperdiploid and t(12;21) Childhood ALL: Implications for Minimal Residual Disease Detection by Flow Cytometry and Clinical Outcome.

Matthew J. Cullen, MSc, Anita J. Dickinson, MSc, Helen Dickinson, BSc, Michael A. Short, BSc, Paul A.S. Evans, PhD, Sally E. Kinsey, MD, Mike Richards, MD, Stephen J. Richards, PhD

Blood (2004) 104 (11): 991.

https://doi.org/10.1182/blood.V104.11.991.991

Published: 2004

NARROW

Improved Outcomes of Budd-Chiari Syndrome in Paroxysmal Nocturnal Hemoglobinuria with Eculizumab Therapy

Successful Pregnancy Outcomes in Paroxysmal Nocturnal Hemoglobinuria with Long-Term Eculizumab Treatment

Eculizumab Reduces Pulmonary Hypertension through Inhibition of Hemolysis-Associated Nitric Oxide Consumption in Patients with Paroxysmal Nocturnal Hemoglobinuria

The Investigation of HMGA2 Dysregulation and Promoter Mutations in PIG-M in the Molecular Pathogenesis of Paroxysmal Nocturnal Haemoglobinuria (PNH).

Abortive Plasma Cell Differentiation with Loss of Mature B-Cell Phenotype in a Subset of Patients with De Novo Diffuse Large B-Cell Lymphoma and Transformed Follicular Lymphoma: Relevance of cMYC Rearrangements.

The Incidence and Prevalence of Paroxysmal Nocturnal Hemoglobinuria (PNH) and Survival of Patients in Yorkshire.

Blockade of Intravascular Hemolysis in PNH with the Terminal Complement Inhibitor Eculizumab Unmasks Low-Level Hemolysis Potentially Occurring through C3 Opsonization.

Nitric Oxide Consumption and Pulmonary Hypertension in Patients with Paroxysmal Nocturnal Hemoglobinuria.

The Effect of Eculizumab Therapy on Red Cell Response Kinetics in Patients with Paroxysmal Nocturnal Hemoglobinuria.

IgH Rearrangements and Mutational Status in Class-Switched IgG B-CLL.

Sustained Control of Hemolysis and Symptoms and Reduced Transfusion Requirements over a Period of 2 Years in Paroxysmal Nocturnal Hemoglobinuria (PNH) with Eculizumab Therapy.

Evolution of GPI-Deficient Clones Predicts Clinical Course in Paroxysmal Nocturnal Haemoglobinuria.

Differential Clearance Kinetics and Phenotypic Alterations of Leukaemic Blast Cells during Induction Therapy for Hyperdiploid and t(12;21) Childhood ALL: Implications for Minimal Residual Disease Detection by Flow Cytometry and Clinical Outcome.

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American Society of Hematology

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American Society of Hematology

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