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Stig Linder, MD PhD
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Journal Articles

Targeted Disruption of USP14 and UCHL5 with the Novel Deubiquitinase Enzyme (DUB) Inhibitor, VLX1570, Induces Immense Proteotoxicity and Cell Death in Malignant Plasma Cells

Aneel Paulus, MDMS, Sharoon Akhtar, MPhil, Maja Kuranz-Blake, B.S., Anne J. Novak, PhD, Stephen Ansell, MD, Morie A Gertz, MD, Robert A Kyle, MD, Peter Martin, MD, Morton Coleman, MD, Sikander Ailawadhi, MD, Stig Linder, MD PhD, Asher Chanan-Khan, MD, Kasyapa S. Chitta, PhD
Journal: Blood
Blood (2014) 124 (21): 3116.
https://doi.org/10.1182/blood.V124.21.3116.3116
Published: 2014
Journal Articles

The Deubiquitinating Enzymes Of The 19S Proteasome Offer Novel Therapeutic Opportunity In Bortezomib Resistant Waldenströms Macroglobulinemia

Aneel Paulus, MD, MS, Kasyapa S. Chitta, PhD, Sharoon Akhtar, Maja Kuranz, Vivek Roy, M.D., Stephen M Ansell, M.D.Ph.D., Anne J. Novak, PhD, Peter Martin, MD, Richard R. Furman, MD, Morton Coleman, MD, Stig Linder, MD, PhD, Asher Chanan-Khan, MD
Journal: Blood
Blood (2013) 122 (21): 4426.
https://doi.org/10.1182/blood.V122.21.4426.4426
Published: 2013
Journal Articles

A Novel Small Molecule Inhibitor Of Deubiquitylating Enzyme USP14 and UCHL5 Induces Apoptosis In Myeloma Cells and Overcomes Bortezomib Resistance

Ze Tian, Ph.D, Padraig D'Arcy, Ph.D, Xin Wang, Ph.D, Arghya Ray, Yu-Tzu Tai, PhD, Yiguo Hu, PhD, Ruben Carrasco, MD, PhD, Deepika Das, Ph.D, Paul Richardson, MD, Stig Linder, MD, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2013) 122 (21): 1923.
https://doi.org/10.1182/blood.V122.21.1923.1923
Published: 2013
Journal Articles

Inhibition Of The Deubiquitinating Enzymes UCHL5 and USP14 Is Lethal To Waldenströms Macroglobulinemia Cells

Kasyapa S. Chitta, PhD, Aneel Paulus, MD, MS, Sharoon Akhtar, Maja Kuranz, Vivek Roy, M.D., Stephen M Ansell, M.D.Ph.D., Anne J. Novak, PhD, Peter Martin, MD, Richard R. Furman, MD, Morton Coleman, MD, Stig Linder, MD, PhD, Asher Chanan-Khan, MD
Journal: Blood
Blood (2013) 122 (21): 1823.
https://doi.org/10.1182/blood.V122.21.1823.1823
Published: 2013