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Takao Deguchi, MD, PhD
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Journal Articles

Predictive Factors of the Development of Leukemia in Patients with Transient Abnormal Myelopoiesis and Down Syndrome: The Jccg Study JPLSG TAM-10

Genki Yamato, MD PhD, Hideki Muramatsu, MD PhD, Tomoyuki Watanabe, PhD, Takao Deguchi, MD PhD, Shotaro Iwamoto, MD, Daisuke Hasegawa, MD PhD, Kiminori Terui, MD PhD, Takahiro Ueda, MD PhD, Tomoko Yokosuka, Tsutomu Toki, PhD, Shiro Tanaka, PhD, Ryu Yanagisawa, Katsuyoshi Koh, MD, Akiko M Saito, MD PhD, Keizo Horibe, MD PhD, Yasuhide Hayashi, MD PhD, Souichi Adachi, MD PhD, Shuki Mizutani, Takashi Taga, MD PhD, Etsuro Ito, MD PhD, Kenichiro Watanabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3833.
https://doi.org/10.1182/blood-2019-125465
Published: 2019
Journal Articles

Intensive Chemotherapy Along with Aggressive Supportive Care Can Spare Stem Cell Transplantation in a Subset of Patients without Compromising an Outcome in Infants with Acute Lymphoblastic Leukemia; A Report from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) Trial MLL-10

Daisuke Tomizawa, MD PhD, Takako Miyamura, MD PhD, Toshihiko Imamura, MD PhD, Tomoyuki Watanabe, PhD, Akiko Moriya Saito, MD PhD, Atsushi Ogawa, MD PhD, Yoshihiro Takahashi, MD PhD, Masahiro Hirayama, MD PhD, Yuki Arakawa, MD, Tomohiko Taki, MD PhD, Takao Deguchi, MD PhD, Toshinori Hori, MD PhD, Sakae Omori, PhD, Masami Haba, PhD, Akihiro Iguchi, MD PhD, Yuuki Koga, MD PhD, Atsushi Manabe, MD PhD, Keizo Horibe, MD PhD, Eiichi Ishii, MD PhD, Katsuyoshi Koh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2626.
https://doi.org/10.1182/blood-2019-121328
Published: 2019
Journal Articles

The Prognostic Value of TP53 Mutations Depends on Clinical Backgrounds in Pediatric Patients with Acute Lymphoblastic Leukemia

Hiroo Ueno, MD, Kenichi Yoshida, MD PhD, Yusuke Shiozawa, MD, PhD, Yasuhito Nannya, MD PhD, Yuka Iijima-Yamashita, PhD, Nobutaka Kiyokawa, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Tomoya Isobe, MD, Masafumi Seki, MD,PhD, Shunsuke Kimura, MD, Hideki Makishima, MD PhD, Nobuyuki Kakiuchi, MD, Keisuke Kataoka, MD PhD, Tetsuichi Yoshizato, MD PhD, Hiroyuki Tsukamoto, MD PhD, Dai Nishijima, PhD, Takao Deguchi, MD PhD, Kentaro Ohki, MD PhD, Atsushi Sato, MD, Hiroyuki Takahashi, Yoshiko Hashii, MD, PhD, Sadao Tokimasa, MD, PhD, Junichi Hara, MD, PhD, Yoshiyuki Kosaka, MD PhD, Koji Kato, MD PhD, Takeshi Inukai, MD, Junko Takita, MD, PhD, Toshihiko Imamura, MD PhD, Satoru Miyano, PhD, Atsushi Manabe, MD PhD, Keizo Horibe, MD PhD, Seishi Ogawa, MD PhD, Masashi Sanada, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4077.
https://doi.org/10.1182/blood-2018-99-115617
Published: 2018
Journal Articles

Distribution and Clinical Features of NOTCH1 Signaling Activating Alterations in Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Shunsuke Kimura, MD, Masafumi Seki, MD, PhD, Kenichi Yoshida, MD PhD, Hiroo Ueno, MD, Yasuhito Nannya, MD PhD, Kentaro Ohki, MD PhD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Ryoji Kobayashi, MD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD PhD, Toshihiko Imamura, MD PhD, Atsushi Sato, MD, Nobutaka Kiyokawa, MD PhD, Atsushi Manabe, MD PhD, Keizo Horibe, MD PhD, Akira Ohara, MD, Masashi Sanada, MD PhD, Mitsuteru Hiwatari, MD PhD, Masao Kobayashi, MD PhD, Akira Oka, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Junko Takita, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4089.
https://doi.org/10.1182/blood-2018-99-111092
Published: 2018
Journal Articles

Negative CD19 Expression Is Associated with Inferior Relapse-Free Survival in RUNX1-RUNX1T1 -Positive Acute Myeloid Leukemia; The Japanese Pediatric Leukemia/Lymphoma Study Group Experience from the AML-05 Study

Toshihiko Imamura, MD PhD, Kenichi Sakamoto, MD PhD, Norio Shiba, MD PhD, Takao Deguchi, MD PhD, Nobutaka Kiyokawa, MD PhD, Yoshiko Hashii, MD, PhD, Akiko Saito, MD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2810.
https://doi.org/10.1182/blood-2018-99-115553
Published: 2018
Journal Articles

Comprehensive Immunophenotyping Panel in Japan Enables to Detect Rare Subtypes in Childhood Leukemia

Takao Deguchi, MD PhD, Nobutaka Kiyokawa, MD PhD, Kentaro Ohki, MD PhD, Yoshiko Hashii, MD, PhD, Atsushi Manabe, Souichi Adachi, MD PhD, Akiko Moriya Saito, MD PhD, Keizo Horibe
Journal: Blood
Blood (2017) 130 (Supplement 1): 5112.
https://doi.org/10.1182/blood.V130.Suppl_1.5112.5112
Published: 2017
Journal Articles

The Outcome of Childhood B-Cell Precursor ALL with ETV6-RUNX1 Treated with Japan Association of Childhood Leukemia Study (JACLS) ALL-02 Trial

Ikuya Usami, Toshihiko Imamura, MD, PhD, Yoshihiro Takahashi, MD PhD, So-ichi Suenobu, MD PhD, Daiichiro Hasegawa, MD PhD, Yoshiko Hashii, MD, PhD, Takao Deguchi, MD PhD, Tsukasa Hori, MD PhD, Akira Shimada, MDPhD, Koji Kato, MD, PhD, Etsuro Ito, MD PhD, Akiko Moriya Saito, MD PhD, Hirohide Kawasaki, MD, Hiroki Hori, MD PhD, Keiko Yumura Yagi, MD PhD, Jun-ichi Hara, MD PhD, Atsushi Sato, MD, Keizo Horibe
Journal: Blood
Blood (2017) 130 (Supplement 1): 2565.
https://doi.org/10.1182/blood.V130.Suppl_1.2565.2565
Published: 2017
Journal Articles

Clinical Effect of Genetic Alterations in Pediatric Patients with B-Progenitor Acute Lymphoblastic Leukemia

Hiroo Ueno, MD, Kenichi Yoshida, MD PhD, Yasuhito Nannya, MD PhD, Yuka Iijima-Yamashita, M.S., Yusuke Shiozawa, MD , PhD, Yuichi Shiraishi, PhD, Tomomi Ishida, Keisuke Kataoka, MD PhD, Tetsuichi Yoshizato, MD,PhD, Hideki Makishima, MD PhD, Nobuyuki Kakiuchi, MD, Masafumi Seki, MD,PhD, Hiroko Tanaka, B.A., Kenichi Chiba, B.A., Takao Deguchi, MD PhD, Atsushi Sato, MD, Yoshiko Hashii, MD, PhD, Sadao Tokimasa, MD, PhD, Junichi Hara, MD, PhD, Yoshiyuki Kosaka, MD, PhD, Koji Kato, MD, PhD, Toshihiko Imamura, MD, PhD, Satoru Miyano, PhD, Keizo Horibe, Seishi Ogawa, MD PhD, Masashi Sanada, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3979.
https://doi.org/10.1182/blood.V130.Suppl_1.3979.3979
Published: 2017
Journal Articles

The Epigenetic and Genetic Landscapes of Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Shunsuke Kimura, Masafumi Seki, MD,PhD, Tomoko Kawai, PhD, Kenichi Yoshida, MD PhD, Tomoya Isobe, Hiroo Ueno, MD, Yusuke Shiozawa, MD , PhD, Hiromichi Suzuki, MD , PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, B.A., Hiroko Tanaka, B.A., Kentaro Ohki, MD PhD, Motohiro Kato, MD, Katsuyoshi Koh, MD, Ryoji Hanada, MD, Ryoji Kobayashi, MD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD, PhD, Toshihiko Imamura, MD, PhD, Atsushi Sato, MD, Nobutaka Kiyokawa, MD PhD, Atushi Manabe, MD PhD, Keizo Horibe, Akira Ohara, MD, Masashi Sanada, MD PhD, Masao Kobayashi, MD PhD, Akira Oka, MD PhD, Yasuhide Hayashi, MD PhD, Satoru Miyano, PhD, Kenichiro Hata, MD PhD, Seishi Ogawa, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1444.
https://doi.org/10.1182/blood.V130.Suppl_1.1444.1444
Published: 2017
Journal Articles

Identifications of Highly Aggressive Phenotype with SPI1 Overexpression in Pediatric T Cell Acute Lymphoblastic Leukemia/Lymphoma

Masafumi Seki, MD PhD, Shunsuke Kimura, MD, Kenichi Yoshida, MD PhD, Tomoya Isobe, MD, Hiroo Ueno, MD, Hiromichi Suzuki, MD PhD, Yusuke Shiozawa, MD, Keisuke Kataoka, MD PhD, Yoichi Fujii, MD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Hiroko Tanaka, BA, Masatoshi Takagi, MD PhD, Atsushi Iwama, MD PhD, Kentaro Oki, MDPhD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Ryoji Hanada, MD, Hiroshi Moritake, MD PhD, Ryoji Kobayashi, MD PhD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD PhD, Toshihiko Imamura, MD PhD, Atsushi Sato, MD, Keizo Horibe, MD PhD, Nobutaka Kiyokawa, MD PhD, Atsushi Manabe, MD PhD, Akira Ohara, MD PhD, Masashi Sanada, MD PhD, Yasuhide Hayashi, MD PhD, Hiroyuki Mano, MDPhD, Satoru Miyano, PhD, Akira Oka, MD PhD, Seishi Ogawa, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2016) 128 (22): 909.
https://doi.org/10.1182/blood.V128.22.909.909
Published: 2016
Journal Articles

The Outcome of Low-Risk Childhood B-Cell Precursor ALL Treated with the Japan Association of Childhood Leukemia Study (JACLS) ALL-02 Trial

Yoshihiro Takahashi, MD PhD, Toshihiko Imamura, MD PhD, Ikuya Usami, MD PhD, Keiko Yumura-Yagi, Soichi Suenobu, Daiichiro Hasegawa, MD PhD, Shinichiro Nishimura, MD PhD, Nobuhiro Suzuki, MDPhD, Yoshiko Hashii, MD PhD, Takao Deguchi, MD PhD, Akiko M. Saito, MD PhD, Yoshihiro Komada, MD PhD, Yoshiyuki Kosaka, MD PhD, Koji Kato, MD PhD, Ryoji Kobayashi, MD PhD, Hirohide Kawasaki, MD PhD, Hiroki Hori, MD PhD, Atsushi Sato, MD PhD, Tooru Kudo, MD PhD, Tatsutoshi Nakahata, MD PhD, Megumi Oda, MD PhD, Junichi Hara, MD PhD, Keizo Horibe, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1604.
https://doi.org/10.1182/blood.V128.22.1604.1604
Published: 2016
Journal Articles

Clusters of Childhood Mixed Phenotype Acute Leukemia Diagnosed By Nation-Wide Immunophenotyping in Japan

Takao Deguchi, MD PhD, Nobutaka Kiyokawa, MD PhD, Kentaro Ohki, MD PhD, Yoshiko Hashii, MD PhD, Atsushi Manabe, MD PhD, Souichi Adachi, MD, PhD, Akiko M. Saito, MD PhD, Keizo Horibe, MD PhD, Yoshihiro Komada, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5277.
https://doi.org/10.1182/blood.V128.22.5277.5277
Published: 2016
Journal Articles

Continuous Cytarabine Plus Dexamethasone in Consolidation Phase to Patients with Childhood ALL: Result from Japan Association of Childhood Leukemia Study - JACLS ALL02 Protocol -

So-ichi Suenobu, MD PhD, Ikuya Usami, MD PhD, Toshihiko Imamura, MD PhD, Hirohide Kawasaki, MD PhD, Keiko Yumura Yagi, MD PhD, Shinichiro Nishimura, MD PhD, Makoto Kaneda, MD PhD, Yoshihiro Takahashi, MD PhD, Daiichiro Hasegawa, MD PhD, Nobuhiro Suzuki, MD PhD, Yoshiko Hashii, MD PhD, Takao Deguchi, MD PhD, Saito Akiko, MD PhD, Koji Kato, MD PhD, Yoshiyuki Kosaka, MD PhD, Mikiya Endo, MD PhD, Akihiro Iguchi, MD PhD, Megumi Oda, MD PhD, Hiroki Hori, MD PhD, Atsushi Sato, MD PhD, Tatsutoshi Nakahata, MD PhD, Tooru Kudoh, MD PhD, Junichi Hara, MD PhD, Keizo Horibe, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2802.
https://doi.org/10.1182/blood.V128.22.2802.2802
Published: 2016
Journal Articles

Risk-Adjusted Therapy of Acute Lymphoblastic Leukemia Can Optimize the Indication of Stem Cell Transplantation and Cranial Irradiation: Results of Japan Association Childhood Leukemia Study Group (JACLS) Protocol ALL-02

Daiichiro Hasegawa, MD PhD, Toshihiko Imamura, MD PhD, Keiko Yagi, MD PhD, Yoshihiro Takahashi, MD PhD, Ikuya Usami, MD PhD, So-ichi Suenobu, MD PhD, Nishimura Shinichiro, MD PhD, Nobuhiro Suzuki, MD PhD, Yoshiko Hashii, MD PhD, Takao Deguchi, MD PhD, Akiko M. Saito, MD PhD, Koji Kato, MD PhD, Yoshiyuki Kosaka, MD PhD, Yoshihiro Komada, MD PhD, Akihiro Iguchi, MD PhD, Hirohide Kawasaki, MD, Hiroki Hori, MD PhD, Atsushi Sato, MD PhD, Tooru Kudo, MD PhD, Tatsutoshi Nakahata, MD PhD, Megumi Oda, MD PhD, Junichi Hara, MD PhD, Keizo Horibe, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3973.
https://doi.org/10.1182/blood.V128.22.3973.3973
Published: 2016
Journal Articles

Landscape of Driver Mutations and Their Clinical Impacts in Pediatric Acute Lymphoblastic Leukemia

Hiroo Ueno, MD, Kenichi Yoshida, MD PhD, Yuka Yamashita, MS, Yusuke Shiozawa, MD, Tomomi Ishida, Hiroyuki Tsukamoto, MD, Yuichi Shiraishi, PhD, Hiroko Tanaka, BA, Kenichi Chiba, BA, Takao Deguchi, MD PhD, Atsushi Sato, MD, Yoshiko Hashii, MD PhD, Sadao Tokimasa, PhD MD, Junichi Hara, MD PhD, Yoshiyuki Kosaka, MD PhD, Koji Kato, MD PhD, Toshihiko Imamura, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Keizo Horibe, MD PhD, Masashi Sanada, MD PhD
Journal: Blood
Blood (2016) 128 (22): 912.
https://doi.org/10.1182/blood.V128.22.912.912
Published: 2016
Journal Articles

Distinct Clinical and Cytogenetic Characteristics and Poor Prognosis in Children with Acute Erythroid Leukemia: A Report from the JPLSG AML-05 Study

Daisuke Tomizawa, MD PhD, Akio Tawa, MD PhD, Nobutaka Kiyokawa, MDPhD, Akitoshi Kinoshita, MD PhD, Hayato Miyachi, MD PhD, Yuka Yamashita, MS, Keizo Horibe, MD PhD, Shotaro Iwamoto, MD PhD, Takao Deguchi, MD PhD, Norio Shiba, MD PhD, Hiroshi Moritake, MD PhD, Akira Shimada, MD PhD, Daisuke Hasegawa, MD PhD, Takashi Taga, MD PhD, Eiichi Ishii, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4945.
https://doi.org/10.1182/blood.V126.23.4945.4945
Published: 2015
Journal Articles

The Characteristics of Blastic Plasmacytoid Dendritic Cell Neoplasms Presenting Leukemia Dissemination, Diagnosed By Nation-Wide Immunophenotyping for Pediatric Hematological Malignancy in Japan

Takao Deguchi, MD PhD, Nobutaka Kiyokawa, MDPhD, Yoshiko Hashii, MD PhD, Akiko M. Saito, Atsushi Manabe, MD PhD, Keizo Horibe, MD PhD, Yoshihiro Komada, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4966.
https://doi.org/10.1182/blood.V126.23.4966.4966
Published: 2015
Journal Articles

A Rapid Approach for the Integrated Central Review of Acute Myeloid Leukemia Diagnosis In a Nationwide Clinical Trial for Children

Akitoshi Kinoshita, MD, PhD, Hayato Miyachi, MD, PhD, Hiromichi Matsushita, MD, PhD, Tomohiko Taki, MD, PhD, Miharu Yabe, MD, PhD, Nobutaka Kiyokawa, MD, PhD, Kiminori Terui, MD, PhD, Hideaki Ohta, MD, PhD, Takao Deguchi, MD, PhD, Hiroyuki Takahashi, MD, PhD, Takashi Taga, MD, PhD, Yasuhide Hayashi, MD, PhD, Akio Tawa, MD, PhD, Souichi Adachi, MD, PhD, Masahito Tsurusawa, MD, PhD, Keizo Horibe, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4833.
https://doi.org/10.1182/blood.V116.21.4833.4833
Published: 2010