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Journal Articles

Apoptosis Signal-Regulating Kinase 1 (Ask1) Inhibition Prevents In Vivo Thrombosis without Compromising Hemostasis

Meghna U Naik, Noor Shaik, Timothy Stalker, Ulhas P. Naik

Blood (2023) 142 (Supplement 1): 681.

https://doi.org/10.1182/blood-2023-190782

Published: 2023

Journal Articles

Deletion of Junctional Adhesion Molecule a (JAM-A) Renders Protection to Mice from Severe Sepsis in a Sex Dependent Manner

Sharath Shankar Sarojini, Meghna U Naik, John C Kostyak, Ulhas P. Naik

Blood (2023) 142 (Supplement 1): 2574.

https://doi.org/10.1182/blood-2023-190798

Published: 2023

Journal Articles

Junctional Adhesion Molecule a (JAM-A) Associates with CD36 upon Platelet Activation and Cytoskeleton in a Phosphorylation-Dependent Manner to Promote Platelet-Platelet Contacts

Sruthi Thekke Veedu, Meghna U Naik, John C Kostyak, Ulhas P. Naik

Blood (2023) 142 (Supplement 1): 2568.

https://doi.org/10.1182/blood-2023-190993

Published: 2023

Journal Articles

Plk3 Deletion Eliminates Bacteremia in an In Vivo Model of Sepsis

John C Kostyak, Sharath S Sarojini, Ulhas P. Naik

Blood (2022) 140 (Supplement 1): 8363–8364.

https://doi.org/10.1182/blood-2022-160291

Published: 2022

Journal Articles

GRK6 Regulates the Hemostatic Response to Injury through Its Rate-Limiting Effects on GPCR Signaling in Platelets

Xi Chen, PhD, Shuchi Gupta, Matthew Cooper, Daniel Dehelian, Xuefei Zhao, Lawrence F. Brass, MD PhD, Ulhas P. Naik, PhD, Meghna Ulhas Naik, MS, Jeffrey Benovic, Peisong Ma, PhD

Blood (2019) 134 (Supplement_1): 3611.

https://doi.org/10.1182/blood-2019-129175

Published: 2019

Journal Articles

iPLA2β Contributes to Activation of Human and Mouse Platelets Via ITAM Receptors Fcγ RIIA and GPVI

Shaji Abraham, PhD, Pravin Patel, BA, Ulhas P. Naik, PhD, Steven Edward McKenzie, MD PhD

Blood (2019) 134 (Supplement_1): 2339.

https://doi.org/10.1182/blood-2019-128426

Published: 2019

Journal Articles

Junctional Adhesion Molecule-a Regulates Vascular Endothelial Growth Factor-a-Dependent Permeability

Meghna Ulhas Naik, MS, Ulhas P. Naik, PhD

Blood (2018) 132 (Supplement 1): 3728.

https://doi.org/10.1182/blood-2018-99-120215

Published: 2018

Journal Articles

Apoptosis Signal-Regulating Kinase 1 (ASK1) Is a Novel Regulator of Heparin-Induced Thrombocytopenia and Thrombosis in Mice

Pravin Patel, BA, Yuhang Zhou, MDPhD, Steven Edward McKenzie, MD PhD, Ulhas P. Naik, PhD

Blood (2017) 130 (Supplement 1): 452.

https://doi.org/10.1182/blood.V130.Suppl_1.452.452

Published: 2017

Journal Articles

Junctional Adhesion Molecule-a, Suppresses Integrin α v β 3 Activation to Control Neovascularization

Meghna Ulhas Naik, MS, Sharmila Chatterjee, PhD, Ulhas P. Naik, PhD

Blood (2017) 130 (Supplement 1): 552.

https://doi.org/10.1182/blood.V130.Suppl_1.552.552

Published: 2017

Journal Articles

ASK1 Activation in Platelets By Oxidized LDL Is Independent of CD36

Kalyan Golla, PhD, Ritu Sharma, PhD, Meghna Ulhas Naik, MS, Ulhas P. Naik, PhD

Blood (2017) 130 (Supplement 1): 1032.

https://doi.org/10.1182/blood.V130.Suppl_1.1032.1032

Published: 2017

Journal Articles

Ask1 regulates murine platelet granule secretion, thromboxane A 2 generation, and thrombus formation

Meghna U. Naik, Pravin Patel, Randall Derstine, Ramya Turaga, Xi Chen, Kalyan Golla, Keith B. Neeves, Hidenori Ichijo, Ulhas P. Naik

Blood (2017) 129 (9): 1197–1209.

https://doi.org/10.1182/blood-2016-07-729780

Published: 2017

Journal Articles

Evaluation of Two Structurally Distinct Novel Inhibitors of Apoptosis Signal-Regulating Kinase 1 (MAP3K5), As Potent Anti-Platelet Agents

Meghna U. Naik, M.Sc., Xi Chen, PhD, Brendan Bachman, M S, Ganesha Rai, PhD, David Maloney, PhD, Arjit Jadhav, PhD, Ulhas P. Naik, PhD FAHA

Blood (2016) 128 (22): 3833.

https://doi.org/10.1182/blood.V128.22.3833.3833

Published: 2016

Journal Articles

The MAP3K Apoptosis Signal-Regulating Kinase 1 (ASK1) Functions As a Calcium-Dependent Regulator of Platelet Activation Downstream of the G(α) q -PLC Signaling Axis

Randall J. Derstine, M.S., Meghna U. Naik, M.Sc., Ulhas P. Naik, PhD FAHA

Blood (2016) 128 (22): 3720.

https://doi.org/10.1182/blood.V128.22.3720.3720

Published: 2016

Journal Articles

ASK1, a Novel Regulator of Thrombosis, Is Activated Downstream of G-Protein Coupled receptors in Human Platelets

Randall Derstine, MS, Meghna Ulhas Naik, MS, Ramya Turaga, PhD, Ulhas P Naik, PhD FAHA

Blood (2014) 124 (21): 4163.

https://doi.org/10.1182/blood.V124.21.4163.4163

Published: 2014

Journal Articles

Integrin α IIb cytoplasmic Tail Is Essential for Integrin Outside-in Signaling and Regulation of in Vivo Thrombosis

Meghna Ulhas Naik, MS, Ulhas P Naik, PhD FAHA

Blood (2014) 124 (21): 4160.

https://doi.org/10.1182/blood.V124.21.4160.4160

Published: 2014

Journal Articles

Bacteria exploit platelets

Ulhas P. Naik

Blood (2014) 123 (20): 3067–3068.

https://doi.org/10.1182/blood-2014-04-565432

Published: 2014

Journal Articles

Junctional adhesion molecule-A suppresses platelet integrin α IIb β 3 signaling by recruiting Csk to the integrin-c–Src complex

Meghna U. Naik, Jeffrey L. Caplan, Ulhas P. Naik

Blood (2014) 123 (9): 1393–1402.

https://doi.org/10.1182/blood-2013-04-496232

Published: 2014

Journal Articles

Identification Of a Novel Small Molecule Inhibitor Of ASK1 As a Potent Anti-Platelet Agent

Meghna Ulhas Naik, MS, Maloney David, Ramya Turaga, Hidinori Ichijo, Ph.D, Ulhas P Naik, Ph.D. FAHA

Blood (2013) 122 (21): 20.

https://doi.org/10.1182/blood.V122.21.20.20

Published: 2013

Journal Articles

Polo-Like Kinase 3, a Novel Regulator of Thrombosis: Positive Regulation of TxA2 Generation, Granular Secretion and Clot Retraction, but Negative Regulation of Integrin Activation

Meghna Ulhas Naik, MS, Brendan Bachman, MS, John C Kostyak, Ph.D, Wei Dai, Ph.D, Ulhas P Naik, Ph.D. FAHA

Blood (2012) 120 (21): 379.

https://doi.org/10.1182/blood.V120.21.379.379

Published: 2012

Journal Articles

Angiogenesis Is Suppressed by Junctional Adhesion Molecule A Through Transcription Factors HIF-1a- and Id1-Dependent Modulation of VEGF/VEGFR2 Expression

Meghna Ulhas Naik, MS, Vesselina Cooke, Ph.D, Sharmila Chatterjee, BS, Ulhas P Naik, Ph.D. FAHA

Blood (2012) 120 (21): 618.

https://doi.org/10.1182/blood.V120.21.618.618

Published: 2012

NARROW

Apoptosis Signal-Regulating Kinase 1 (Ask1) Inhibition Prevents In Vivo Thrombosis without Compromising Hemostasis

Deletion of Junctional Adhesion Molecule a (JAM-A) Renders Protection to Mice from Severe Sepsis in a Sex Dependent Manner

Junctional Adhesion Molecule a (JAM-A) Associates with CD36 upon Platelet Activation and Cytoskeleton in a Phosphorylation-Dependent Manner to Promote Platelet-Platelet Contacts

Plk3 Deletion Eliminates Bacteremia in an In Vivo Model of Sepsis

GRK6 Regulates the Hemostatic Response to Injury through Its Rate-Limiting Effects on GPCR Signaling in Platelets

iPLA2β Contributes to Activation of Human and Mouse Platelets Via ITAM Receptors Fcγ RIIA and GPVI

Junctional Adhesion Molecule-a Regulates Vascular Endothelial Growth Factor-a-Dependent Permeability

Apoptosis Signal-Regulating Kinase 1 (ASK1) Is a Novel Regulator of Heparin-Induced Thrombocytopenia and Thrombosis in Mice

Junctional Adhesion Molecule-a, Suppresses Integrin α v β 3 Activation to Control Neovascularization

ASK1 Activation in Platelets By Oxidized LDL Is Independent of CD36

Ask1 regulates murine platelet granule secretion, thromboxane A 2 generation, and thrombus formation

Evaluation of Two Structurally Distinct Novel Inhibitors of Apoptosis Signal-Regulating Kinase 1 (MAP3K5), As Potent Anti-Platelet Agents

The MAP3K Apoptosis Signal-Regulating Kinase 1 (ASK1) Functions As a Calcium-Dependent Regulator of Platelet Activation Downstream of the G(α) q -PLC Signaling Axis

ASK1, a Novel Regulator of Thrombosis, Is Activated Downstream of G-Protein Coupled receptors in Human Platelets

Integrin α IIb cytoplasmic Tail Is Essential for Integrin Outside-in Signaling and Regulation of in Vivo Thrombosis

Bacteria exploit platelets

Junctional adhesion molecule-A suppresses platelet integrin α IIb β 3 signaling by recruiting Csk to the integrin-c–Src complex

Identification Of a Novel Small Molecule Inhibitor Of ASK1 As a Potent Anti-Platelet Agent

Polo-Like Kinase 3, a Novel Regulator of Thrombosis: Positive Regulation of TxA2 Generation, Granular Secretion and Clot Retraction, but Negative Regulation of Integrin Activation

Angiogenesis Is Suppressed by Junctional Adhesion Molecule A Through Transcription Factors HIF-1a- and Id1-Dependent Modulation of VEGF/VEGFR2 Expression

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American Society of Hematology

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American Society of Hematology

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