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Weihua Song, M.D.
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Journal Articles

Targeting MEK1/2 Signaling Cascade by AS703026, a Novel Selective MEK1/2 Inhibitor, Induces Pleiotropic Anti-Myeloma Activity in Vitro and In Vivo.

Yu-Tzu Tai, Ph.D., Kihyun Kim, M.D., Xian-Feng Li, M.S., Mariateresa Fulciniti, Ph.D., Weihua Song, M.D., Sabikun Nahar, B.S., Peter Burger, B.S., Mathew J. Rumizen, Klaus Podar, M.D., Ph.D., Dharminder Chauhan, Ph.D, Teru Hideshima, M.D., Ph.D., Robert L Schlossman, M.D., Ph.D., Nikhil C. Munshi, Paul Richardson, M.D., Ph.D., Ann Clark, Ph.D., Janet Ogden, Ph.D., Goutopoulos Andreas, Ph.D., Luca Rastelli, Ph.D., Kenneth C. Anderson, MD
Journal: Blood
Blood (2009) 114 (22): 3848.
https://doi.org/10.1182/blood.V114.22.3848.3848
Published: 2009
Journal Articles

Low Levels of Circulating CS1, a Newly Identified Multiple Myeloma (MM) Antigen for a Novel Humanized HuLuc63 Monoclonal Antibody, Is Detected in MM Patient Sera and Correlates with Active Disease.

Yu-Tzu Tai, PhD, Audie G. Rice, Ph.D., Marav Leiba, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Weihua Song, M.D., Rao Prabhala, Ph.D., Myles Dillon, B.S., Edie Tolan, Ph.D., Xanling Xie, Ph.D., Teru Hideshima, M.D., Ph.D., Noopur Raje, M.D., Paul Richardson, M.D., Nihkil C. Munshi, M.D., Arnon Nagler, M.D., Herve Avet-Loiseau, M.D., Daniel E.H. Afar, Ph.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2007) 110 (11): 1509.
https://doi.org/10.1182/blood.V110.11.1509.1509
Published: 2007
Journal Articles

Activation of B-Cell Maturation Antigen (BCMA) on Human Multiple Myeloma Cells by a Proliferation-Inducing Ligand (APRIL) Promotes Myeloma Cell Function in the Bone Marrow Microenvironment.

Merav Leiba, M.D., Jiangchun Xu, M.D., Ph.D., Weihua Song, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Jennifer Kordich, M.S., Linda Cassiano, B.A., Klaus Podar, M.D., Ph.D., Dharminder Chauhan, Ph.D., Teru Hideshima, M.D., Ph.D., Nikhil C. Munshi, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Yu-Tzu Tai, PhD
Journal: Blood
Blood (2007) 110 (11): 1503.
https://doi.org/10.1182/blood.V110.11.1503.1503
Published: 2007
Journal Articles

Acquisition of New In Vivo Genomic Change over Time in Multiple Myeloma.

Yu-Tzu Tai, PhD, Leutz Buon, M.S., Benjamin King, B.S., Cheng Li Cheng Li, Ph.D., Peter Burger Peter Burger, B.S., Xian-Feng Li, M.S., Weihua Song, M.D., Robert Schlossman, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Nikhil Munshi, M.D.
Journal: Blood
Blood (2007) 110 (11): 2481.
https://doi.org/10.1182/blood.V110.11.2481.2481
Published: 2007
Journal Articles

CS1, a New Surface Target on Multiple Myeloma (MM) Cells, Protects Myeloma Cells from Apoptosis Via Regulation of ERK1/2, AKT and STAT3 Signaling Cascades.

Yu-Tzu Tai, PhD, Giovanni Tonon, M.D., Ph.D., Merav Leiba, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Weihua Song, M.D., Klaus Podar, M.D., Ph.D., Dharminder Chauhan, Ph.D., Nihkil Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2007) 110 (11): 109.
https://doi.org/10.1182/blood.V110.11.109.109
Published: 2007
Journal Articles

Genomic Evolution of Multiple Myeloma In Vivo over Time.

Yu-Tzu Tai, PhD, Benjamin King, B.S., Cheng Li, Ph.D., XianFeng Li, M.S., Peter Burger, B.S., Weihua Song, M.D., Masood Shammas, Ph.D., Robert Schlossman, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Nikhil C. Munshi, M.D.
Journal: Blood
Blood (2006) 108 (11): 3400.
https://doi.org/10.1182/blood.V108.11.3400.3400
Published: 2006
Journal Articles

Inhibition of ERK1/2 Activity by the MEK1/2 Inhibitor AZD6244 (ARRY-142886) Induces Human Multiple Myeloma Cell Apoptosis in the Bone Marrow Microenvironment: A New Therapeutic Strategy for MM.

Yu-Tzu Tai, PhD, Xian-Feng Li, M.S., Iris Breitkreutz, M.D., Weihua Song, M.D., Peter Burger, B.S., Matthew Rumizen, Teru Hideshima, M.D. Ph.D., Klaus Podar, M.D. Ph.D., Irene Ghobrial, M.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3460.
https://doi.org/10.1182/blood.V108.11.3460.3460
Published: 2006
Journal Articles

The MEK1/2 Inhibitor AZD6244 (ARRY-142886) Downregulates Constitutive and Adhesion-Induced c- MAF Oncogene Expression and Its Downstream Targets in Human Multiple Myeloma.

Yu-Tzu Tai, PhD, Giovanni Tonon, Ph.D., Xian-Feng Li, M.S., Matthew Rumizen, Weihua Song, M.D., Aileen Morrison, B.S., Peter Burger, B.S., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3463.
https://doi.org/10.1182/blood.V108.11.3463.3463
Published: 2006
Journal Articles

Killing of Drug-Sensitive and Resistant Myeloma Cells and Disruption of Their Bone Marrow Stromal Interaction by HuLuc63, a Novel Humanized Anti-CS1 Monoclonal Antibody.

Yu-Tzu Tai, PhD, Weihua Song, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Robert Schlossman, M.D., Audie Rice, Ph.D., Anne van Abbema, Ph.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Daniel Afar, Ph.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3470.
https://doi.org/10.1182/blood.V108.11.3470.3470
Published: 2006