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Journal Articles

Direct Visualization of Platelet Integrins Using ANTI-Transmembrane Domain Peptides Containing a BLUE Fluorescent Amino Acid

Karen Pei Yi Fong, PhD BS, Ismail A. Ahmed, PhD, Marco Mravic, B.S., M.S., Hyunil Jo, PhD, William F. DeGrado, PhD, Feng Gai, PhD, Joel S. Bennett, MD

Blood (2019) 134 (Supplement_1): 2344.

https://doi.org/10.1182/blood-2019-128363

Published: 2019

Journal Articles

Active Calpain Promotes Fibrin Clot Contraction By Strengthening the Coupling of Fibrin-Bound αIIbβ3 to the Platelet Cytoskeleton

Rustem I. Litvinov, Karen Pei Yi Fong, PhD BS, Oleg V. Kim, PhD, Kathleen I. Molnar, PhD, Paul C. Billings, PhD, Alex Sternisha, BS, James A. Wells, PhD, John W. Weisel, PhD, William F. DeGrado, PhD, Joel S. Bennett, MD

Blood (2018) 132 (Supplement 1): 1128.

https://doi.org/10.1182/blood-2018-99-113063

Published: 2018

Journal Articles

Unique Transmembrane Domain Interactions Differentially Modulate Platelet αIIbβ3 and αvβ3 Function

Rustem I. Litvinov, MD PhD, Marco Mravic, B.S., M.S., Hua Zhu, BS, John W. Weisel, PhD, William F. DeGrado, PhD, Joel S. Bennett, MD

Blood (2017) 130 (Supplement 1): 1019.

https://doi.org/10.1182/blood.V130.Suppl_1.1019.1019

Published: 2017

Journal Articles

Integrin αIIbβ3-Mediated c-Src Activation: Differential Binding to Inactive and Active c-Src

Lisa Span, Patrik Nygren, PhD, Yibing Wu, PhD, Hua Zhu, BS, David T. Moore, MD PhD, Hong Cheng, PhD, Heinrich Roder, PhD, William F. DeGrado, PhD, Joel S. Bennett, MD

Blood (2014) 124 (21): 4158.

https://doi.org/10.1182/blood.V124.21.4158.4158

Published: 2014

Journal Articles

Protein-Protein and Protein-Lipid Interactions Modulate αIIbβ3 Inside-out Signaling.

David T. Moore, BA, MS, Patrik Nygren, PhD, Kathleen Molnar, BS, Kathleen Boesze-Battaglia, PhD, Joel S. Bennett, MD, William F. DeGrado, PhD

Blood (2009) 114 (22): 152.

https://doi.org/10.1182/blood.V114.22.152.152

Published: 2009

Journal Articles

Identification of Stalk Mutations That Stabilize the High Affinity Conformation of αIIbβ3 by Negative Design.

Jason E. Donald, PhD, Hua Zhu, BS, William F. DeGrado, PhD, Joel S. Bennett, MD

Blood (2009) 114 (22): 4017.

https://doi.org/10.1182/blood.V114.22.4017.4017

Published: 2009

Journal Articles

Factors Influencing the Homomeric and Heteromeric Association of Platelet Integrin Transmembrane Domains.

Bryan W. Berger, PhD, Roman Gorelik, BS, William F. DeGrado, PhD, Joel S. Bennett, MD

Blood (2006) 108 (11): 212.

https://doi.org/10.1182/blood.V108.11.212.212

Published: 2006

Journal Articles

Computational Design of a Model for the Platelet Integrin αIIbβ3.

Douglas G. Metcalf, BS, William F. DeGrado, PhD, Joel S. Bennett, MD

Blood (2006) 108 (11): 1528.

https://doi.org/10.1182/blood.V108.11.1528.1528

Published: 2006

Journal Articles

Regulation of the Function of αvβ3 in Platelets by a Designed Peptide Targeting the αv Transmembrane Domain.

Hang Yin, PhD, Joanna S. Slusky, BS, Bryan W. Berger, PhD, Rustem I. Litvinov, PhD, Gaston Vilaire, BA, James D. Lear, PhD, William F. DeGrado, PhD, Joel S. Bennett, MD

Blood (2006) 108 (11): 1504.

https://doi.org/10.1182/blood.V108.11.1504.1504

Published: 2006

Journal Articles

The Development of Small Molecule Inhibitors of Collagen Binding to the Integrin α2β1 as Antithrombotic Drugs.

Sungwook Choi, BS, Seth E. Snyder, PhD, David T. Moore, BA, MS, Gaston Vilaire, BA, Joel S. Bennett, MD, William F. DeGrado, PhD

Blood (2005) 106 (11): 3677.

https://doi.org/10.1182/blood.V106.11.3677.3677

Published: 2005

Journal Articles

Activation of Platelet α Iibβ 3 by Exogenous Peptides Corresponding to the Transmembrane Domains of α Iib and β 3.

Hang Yin, PhD, Hua Zhu, PhD, Gaston Vilaire, BS, Wei Li, MD, Rustem I. Litvinov, PhD, William F. DeGrado, PhD, Joel S. Bennett, MD

Blood (2005) 106 (11): 384.

https://doi.org/10.1182/blood.V106.11.384.384

Published: 2005

Journal Articles

Two Specific Domains on the Upper Surface of the αIib β Propeller Determine the Sensitivity of αIibβ3 for RGD-Containing Peptides.

Ramesh B. Basani, PhD, Michael A. Thornton, PhD, Bruce S. Sachais, MD, PhD, M. Anna Kowalska, PhD, William F. Degrado, PhD, Joel S. Bennett, MD, Mortimer Poncz, MD

Blood (2005) 106 (11): 2653.

https://doi.org/10.1182/blood.V106.11.2653.2653

Published: 2005

NARROW

Direct Visualization of Platelet Integrins Using ANTI-Transmembrane Domain Peptides Containing a BLUE Fluorescent Amino Acid

Active Calpain Promotes Fibrin Clot Contraction By Strengthening the Coupling of Fibrin-Bound αIIbβ3 to the Platelet Cytoskeleton

Unique Transmembrane Domain Interactions Differentially Modulate Platelet αIIbβ3 and αvβ3 Function

Integrin αIIbβ3-Mediated c-Src Activation: Differential Binding to Inactive and Active c-Src

Protein-Protein and Protein-Lipid Interactions Modulate αIIbβ3 Inside-out Signaling.

Identification of Stalk Mutations That Stabilize the High Affinity Conformation of αIIbβ3 by Negative Design.

Factors Influencing the Homomeric and Heteromeric Association of Platelet Integrin Transmembrane Domains.

Computational Design of a Model for the Platelet Integrin αIIbβ3.

Regulation of the Function of αvβ3 in Platelets by a Designed Peptide Targeting the αv Transmembrane Domain.

The Development of Small Molecule Inhibitors of Collagen Binding to the Integrin α2β1 as Antithrombotic Drugs.

Activation of Platelet α Iibβ 3 by Exogenous Peptides Corresponding to the Transmembrane Domains of α Iib and β 3.

Two Specific Domains on the Upper Surface of the αIib β Propeller Determine the Sensitivity of αIibβ3 for RGD-Containing Peptides.

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American Society of Hematology

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American Society of Hematology

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