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Journal Articles

Prognostic Value of Refined Disease Risk Index (rDRI) and Conditioning Regimen in Adult Patients Receiving Unrelated Cord Blood Transplantation (UCBT) for Haematological Malignancies - 15-Year Follow-up of Multicenter Study in Singapore

Qianhuang Ian Q Wu, MBBS, Yeh Ching Linn, MBBS, MRCP, William YK Hwang, MBBS, Michelle Poon, MBBS, MRCP, FRCPATH, Lip Kun Tan, MBBS, FRCP, FRCPath, Yang Liang Boo, MD, Yeow Tee Goh, MBBS, Aloysius YL Ho, MBBS,FRCP,FRCPath, Liang Piu Koh, MBBS, MRCP

Blood (2020) 136 (Supplement 1): 22–23.

https://doi.org/10.1182/blood-2020-141581

Published: 2020

Journal Articles

Phase I/II Dose-Escalation Study of Lenalidomide in Combination with R-GDP for Treatment of Transplant-Ineligible Relapsed/Refractory Diffuse Large B-Cell Lymphoma Followed By Maintenance Lenalidomide

Colin Phipps, MD, Chandramouli Nagarajan, MBBS, Lawrence Ng, MBBS, Jane L Chua, Yunxin Chen, MBBS, Shin Yeu Ong, MD, Melinda Si Yun Tan, MBBS, Nicholas Francis Grigoropoulos, MD PhD, Sathish Gopalakrishnan, MD, Heng Joo Ng, MBBS, William YK Hwang, MBBS, Yeow Tee Goh, MBBS, Yuh Shan Lee, MBBS

Blood (2020) 136 (Supplement 1): 25–26.

https://doi.org/10.1182/blood-2020-142275

Published: 2020

Journal Articles

High Dose Flamsa, CLAG or FLAG-Based Sequential Conditioning Regimen Followed By Allogeneic Hematopoietic Transplantation Results in Favorable Outcome for High Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasia Patients : A Multicenter Study in Singapore

Lip Leong Chong, MDMRCP, Yang Liang Boo, MD, Yin Jie Koh, Michelle Poon, MBBS, MRCP, FRCPATH, Yeh Ching Linn, MBBS, MRCP, William YK Hwang, MBBS, Aloysius YL Ho, MBBS,FRCP,FRCPath, Elson Neo, Lip Kun Tan, MBBS, FRCP, FRCPath, Liang Piu Koh, MBBS, MRCP

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-141518

Published: 2020

Journal Articles

Single Cell Immune Profiling Reveals Distinct T Cell Clones and Functional States in in-Vitro Expanded Cord Blood Derived Gamma Delta T Cells

Kar Wai Tan, PhD, Zhihui Li, Joey Lai, Dianyan Guo, Yeh Ching Linn, MBBS, MRCP, William YK Hwang, MBBS, Shang Li, MD PhD, Connie J. Eaves, PhD, Yeow Tee Goh, MBBS, Alice Cheung, PhD

Blood (2020) 136 (Supplement 1): 35–36.

https://doi.org/10.1182/blood-2020-140667

Published: 2020

Journal Articles

A Biophysically Defined MSC Subpopulation for Enhanced Homing and Immunosuppression

Zhiyong Poon, Xiubo Fan, PhD, Alice Cheung, PhD, Sudipto Bari, PhD, William YK Hwang, MBBS, FRCP

Blood (2019) 134 (Supplement_1): 2078.

https://doi.org/10.1182/blood-2019-126683

Published: 2019

Journal Articles

Unmanipulated Haploidentical Transplant Followed By Post-Transplant Cyclophosphamide and Selective Ex Vivo T-Cell Depleted Haploidentical Transplant Results in Comparable Outcome As Unrelated Cord Blood Transplant for Adults with Haematological Malignancies- a Multicenter Study in Singapore

Cheryl XQ Lim, MBBS,MRCP, Yeh Ching Linn, MBBS, MRCP, Yin Jie Koh, Michelle Poon, MBBS, MRCP, FRCPATH, Aloysius YL Ho, MBBS,FRCP,FRCPath, William YK Hwang, MBBS, FRCP, Lip Kun Tan, MBBS, FRCP, FRCPath, Liang Piu Koh, MBBS, MRCP

Blood (2019) 134 (Supplement_1): 4588.

https://doi.org/10.1182/blood-2019-125261

Published: 2019

Journal Articles

High Dose Flamsa, CLAG or FLAG-Based Sequential Conditioning Regimen Followed By Allogeneic Hematopoietic Transplantation Results in Favorable Outcome for High Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasia Patients: A Multicenter Study in Singapore

Yin Jie Koh, Michelle Poon, MBBS, MRCP, FRCPATH, Yeh Ching Linn, MBBS, MRCP, William YK Hwang, MBBS, FRCP, Elson Neo, Aloysius YL Ho, MBBS,FRCP,FRCPath, Lip Kun Tan, MBBS, FRCP, FRCPath, Liang Piu Koh, MBBS, MRCP

Blood (2019) 134 (Supplement_1): 4509.

https://doi.org/10.1182/blood-2019-125246

Published: 2019

Journal Articles

Preliminary Results of a Phase 2a Dose Optimization Study of ASLAN003 (DHODH inhibitor) in Acute Myeloid Leukemia (AML) Patients Who Are Ineligible for Standard Therapy; Early Signs of Activity

Stephen B Ting, MB BS, FRACP, FRCPA, PhD, Chin Hin Ng, MD MRCP, Ashish Bajel, MBBS, FRACP, FRCPA, William YK Hwang, MBBS, FRCP(London), MMed(Int MD, FAMS, Shir-Jing Ho, MBBS, FRACP, FRCPA, MClinTrial Res, Wee-Joo Chng, MBBS, PhD FRCPath, FRCP, Mark McHale, B.S., PhD, Chih-Yi Hsieh, MD, Hsuan-Jen Shih, MD, Nicola McIntyre, PhD, Jamie Kwek, Wei-Ling Chang, PhD, Bertil Lindmark, MD PhD

Blood (2018) 132 (Supplement 1): 2676.

https://doi.org/10.1182/blood-2018-99-110570

Published: 2018

Journal Articles

Nicord Single Unit Expanded Umbilical Cord Blood Transplantation: Final Results of a Multicenter Phase I/ II Trial

Mitchell E. Horwitz, MD, Daniela Cilloni, MD, David Valcarcel, Francesco Frassoni, MD, Jaap Jan Boelens, MD PhD, Madan Jagasia, MD MBBS, MS, John E. Wagner, MD, Jurgen Kuball, MD, Liang Piu Koh, Navneet S. Majhail, MD MS, Patrick J. Stiff, MD, Rabi Hanna, MD, Richard Thomas T. Maziarz, MD, William YK Hwang, MBBS, FRCP, Pau Montesinos, MD PhD, Joanne Kurtzberg, MD, Guillermo Sanz, MD

Blood (2017) 130 (Supplement 1): 847.

https://doi.org/10.1182/blood.V130.Suppl_1.847.847

Published: 2017

Journal Articles

Manipulating Osteogenic/Adipogenic Balance in Mesenchymal Stromal Cells (MSCs) for Hematopoietic Applications

Zhiyong Poon, PhD, Xiubo Fan, PhD, Alice Cheung, PhD, Sudipto Bari, PhD, Niraja Dighe, MS, Krystyn Van Vliet, PhD, William YK Hwang, MBBS, FRCP(London), MMed(Int MD, FAMS

Blood (2017) 130 (Supplement 1): 3782.

https://doi.org/10.1182/blood.V130.Suppl_1.3782.3782

Published: 2017

Journal Articles

Evaluating the Mesenchymal Stromal Cell (MSCs) Contribution in Pre-Leukemic Myelodysplastic Syndromes in Different Patient Risk Groups

Zhiyong Poon, PhD, Niraja Dighe, MS, Xiubo Fan, PhD, Alice Cheung, PhD, Sudipto Bari, PhD, William YK Hwang, MBBS, FRCP(London), MMed(Int MD, FAMS

Blood (2017) 130 (Supplement 1): 1680.

https://doi.org/10.1182/blood.V130.Suppl_1.1680.1680

Published: 2017

Journal Articles

Mechanism of Action of Azacytidine in Myelodysplastic Syndromes (MDS)

Niraja Dighe, M.Sc, Subhashree Venkatesan, B.tech, Poon Zhiyong, PhD, William YK Hwang, MBBS, MRCP, FRCP

Blood (2016) 128 (22): 4315.

https://doi.org/10.1182/blood.V128.22.4315.4315

Published: 2016

Journal Articles

High Dose Cytarabine Is Superior to Intermediate Dose Cytarabine As Post-Remission Therapy for Younger Patients with Favorable Risk Acute Myeloid Leukemia

Nurul Aidah Abdul Halim, MBBS, MRCP, Gee Chuan Wong, MBBS, MRCP, FRCP, Ho YL Aloysius, MBBS, MRCP, FRCPath, William YK Hwang, MBBS, MRCP, FRCP, Yeh Ching Linn, Zhentang Lao, MBBS, MRCP

Blood (2016) 128 (22): 4032.

https://doi.org/10.1182/blood.V128.22.4032.4032

Published: 2016

Journal Articles

Small Molecule Based Ex Vivo Expansion of CD34 + CD90 + CD49f + Hematopoietic Stem & Progenitor Cells from Non-Enriched Umbilical Cord Blood Mononucleated Cells

Sudipto Bari, BEng, Qixing Zhong, MSc, Christina LL Chai, PhD, Gigi NC Chiu, PhD, William YK Hwang, MBBS, MRCP, FRCP

Blood (2016) 128 (22): 2321.

https://doi.org/10.1182/blood.V128.22.2321.2321

Published: 2016

Journal Articles

Time from Diagnosis to Initiation of Curative Chemotherapy Affects Outcomes in DLBCL - Data from a Large Asian Cohort

Colin Phipps, MBBS, MRCP, FRCPath, Yuh Shan Lee, MBBS, MRCP, FRCPath, Chandramouli Nagarajan, MBBS, MD MRCP, Yunxin Chen, MBBS, MRCP, FRCPath, Allan ZK Goh, Lay Poh Khoo, BSc, Kevin Tay, MD, Miriam Tao, MD, Richard Quek, Tiffany Tang, MD, Mohamad Farid, MD, Soon Thye Lim, MBBS, MRCP, Sathish Kumar Gopalakrishnan, FRCPath, Nicholas F Grigoropoulos, MRCP, FRCPath, Yvonne Loh, MBBS, MRCP, Daryl Tan, MBBS, MRCP, William YK Hwang, MBBS, MRCP, FRCP, Yeow Tee Goh, MD

Blood (2016) 128 (22): 1871.

https://doi.org/10.1182/blood.V128.22.1871.1871

Published: 2016

Journal Articles

In Vitro Expanded γδ T Cells Derived from Cord Blood Induce Potent and Specific Cytotoxicity Against Human Acute Myeloid Leukemia Cells

Alice MS Cheung, PhD, Kar Wai Tan, PhD, Dian Yan Guo, BSc, Su-Ann Goh, BSc, Amanda SY Lau, BSc, Yeh Ching Linn, MBBS, MRCP, William YK Hwang, MBBS, MRCP, FRCP, Yeow Tee Goh, MD, Shang Li, MD PhD

Blood (2016) 128 (22): 2168.

https://doi.org/10.1182/blood.V128.22.2168.2168

Published: 2016

Journal Articles

Mefloquine Effectively Targets Blast Phase Chronic Myeloid Leukemia through Inducing Oxidative Stress and Lysosomal Disruption

Wei Xiang, PhD, Yi Hui Lam, Collin Sng, May Anne Cheong, MBBS, MRCP, Hein Than, MD, William YK Hwang, MBBS, MRCP, FRCP, Charles Chuah

Blood (2016) 128 (22): 5426.

https://doi.org/10.1182/blood.V128.22.5426.5426

Published: 2016

Journal Articles

Impact of Post-Remission Consolidation Modalities in the Clinical Outcomes of Acute Myeloid Leukemia Patients in First Remission - Is There a Role for Autologous Hematopoietic Stem Cell Transplant?

May Anne Cheong, MBBS, MRCP, Gee Chuan Wong, MBBS, MRCP, FRCP, William YK Hwang, MBBS, MRCP, FRCP, Ho YL Aloysius, MBBS, MRCP, FRCPath, Yeh Ching Linn, MBBS, MRCP, Yeow-Tee YT Goh, MD, Yvonne Loh, MBBS, MRCP, Sathish Kumar, MBBS, MRCP, FRCPath, Colin Phipps, MBBS, MRCP, FRCPath, Zhentang Lao, MBBS, MRCP

Blood (2015) 126 (23): 3184.

https://doi.org/10.1182/blood.V126.23.3184.3184

Published: 2015

Journal Articles

Bortezomib (BTZ) and Panobinostat (PAN) Combination Is Effective in Patients with Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) or NK/T-Cell Lymphoma (NKL) and Maintenance Treatment May Be Essential for Sustained Response

Daryl Tan, MD, William YK Hwang, MBBS, FRCP, FAMS, Colin Phipps Diong, Wee Lee Goh, BSC, Lionel K.Y See, BSc, Yiong Huak Chan, PHD, Soon Thye Lim, MRCP MBBS, Soo Chin Ng, MBBS MRCP, S Fadilah, MBBS, Soo-Yong Tan, MBBS, FRCPath, DPhil, Won Seog Kim, MD, Yeow Tee Goh, MD

Blood (2012) 120 (21): 3669.

https://doi.org/10.1182/blood.V120.21.3669.3669

Published: 2012

Journal Articles

Effectiveness of Ursodeoxycholic Acid As Prophylactic Agent Against Hepatic Sinusoidal Obstruction Syndrome in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Treatment of Hematological Malignancies

Hong Yen HY Ng, B.Sc(Pharm)(Hons), BCOP, Mui Fong MF Chong, BSc (Pharm)(Hons), Jielin JL Song, BSc (Pharm)(Hons), William YK Hwang, MBBS, FRCP, FAMS, Yeh Ching Linn, MD, Yvonne SM Loh, MBBS, MRCP, Aloysius YL Ho, Yeow-Tee YT Goh, MD

Blood (2012) 120 (21): 4165.

https://doi.org/10.1182/blood.V120.21.4165.4165

Published: 2012

NARROW

Prognostic Value of Refined Disease Risk Index (rDRI) and Conditioning Regimen in Adult Patients Receiving Unrelated Cord Blood Transplantation (UCBT) for Haematological Malignancies - 15-Year Follow-up of Multicenter Study in Singapore

Phase I/II Dose-Escalation Study of Lenalidomide in Combination with R-GDP for Treatment of Transplant-Ineligible Relapsed/Refractory Diffuse Large B-Cell Lymphoma Followed By Maintenance Lenalidomide

High Dose Flamsa, CLAG or FLAG-Based Sequential Conditioning Regimen Followed By Allogeneic Hematopoietic Transplantation Results in Favorable Outcome for High Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasia Patients : A Multicenter Study in Singapore

Single Cell Immune Profiling Reveals Distinct T Cell Clones and Functional States in in-Vitro Expanded Cord Blood Derived Gamma Delta T Cells

A Biophysically Defined MSC Subpopulation for Enhanced Homing and Immunosuppression

Unmanipulated Haploidentical Transplant Followed By Post-Transplant Cyclophosphamide and Selective Ex Vivo T-Cell Depleted Haploidentical Transplant Results in Comparable Outcome As Unrelated Cord Blood Transplant for Adults with Haematological Malignancies- a Multicenter Study in Singapore

High Dose Flamsa, CLAG or FLAG-Based Sequential Conditioning Regimen Followed By Allogeneic Hematopoietic Transplantation Results in Favorable Outcome for High Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasia Patients: A Multicenter Study in Singapore

Preliminary Results of a Phase 2a Dose Optimization Study of ASLAN003 (DHODH inhibitor) in Acute Myeloid Leukemia (AML) Patients Who Are Ineligible for Standard Therapy; Early Signs of Activity

Nicord Single Unit Expanded Umbilical Cord Blood Transplantation: Final Results of a Multicenter Phase I/ II Trial

Manipulating Osteogenic/Adipogenic Balance in Mesenchymal Stromal Cells (MSCs) for Hematopoietic Applications

Evaluating the Mesenchymal Stromal Cell (MSCs) Contribution in Pre-Leukemic Myelodysplastic Syndromes in Different Patient Risk Groups

Mechanism of Action of Azacytidine in Myelodysplastic Syndromes (MDS)

High Dose Cytarabine Is Superior to Intermediate Dose Cytarabine As Post-Remission Therapy for Younger Patients with Favorable Risk Acute Myeloid Leukemia

Small Molecule Based Ex Vivo Expansion of CD34 + CD90 + CD49f + Hematopoietic Stem & Progenitor Cells from Non-Enriched Umbilical Cord Blood Mononucleated Cells

Time from Diagnosis to Initiation of Curative Chemotherapy Affects Outcomes in DLBCL - Data from a Large Asian Cohort

In Vitro Expanded γδ T Cells Derived from Cord Blood Induce Potent and Specific Cytotoxicity Against Human Acute Myeloid Leukemia Cells

Mefloquine Effectively Targets Blast Phase Chronic Myeloid Leukemia through Inducing Oxidative Stress and Lysosomal Disruption

Impact of Post-Remission Consolidation Modalities in the Clinical Outcomes of Acute Myeloid Leukemia Patients in First Remission - Is There a Role for Autologous Hematopoietic Stem Cell Transplant?

Bortezomib (BTZ) and Panobinostat (PAN) Combination Is Effective in Patients with Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) or NK/T-Cell Lymphoma (NKL) and Maintenance Treatment May Be Essential for Sustained Response

Effectiveness of Ursodeoxycholic Acid As Prophylactic Agent Against Hepatic Sinusoidal Obstruction Syndrome in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Treatment of Hematological Malignancies

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American Society of Hematology

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ASH Publications

American Society of Hematology

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