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Wolfgang Hiddemann, MD
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Journal Articles

PTPN11 mutations and Outcomes in Adult Patients with Acute Myeloid Leukemia

Klaus H. Metzeler, MD, Maja Rothenberg-Thurley, PhD, Dennis Görlich, PhD, Maria Cristina Sauerland, Annika Maria Dufour, PhD, Stephanie Schneider, PhD, Marion Subklewe, MD, Jan Braess, MD, Bernhard J. Wörmann, MD, Wolfgang E. Berdel, Prof., MD, Utz Krug, MD, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, MD, Tobias Herold, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-137487
Published: 2020
Journal Articles

Aberrant Cathepsin S Induces a Supportive Immune Microenvironment in Follicular Lymphoma

Johannes Adrian Hildebrand, MSc, BSc, Deepak Bararia, Sebastian Stolz, Sarah Haebe, MD, Stefan Alig, Michael Bartoschek, Michael Boesl, Alessandro Pastore, Erik Gaitzsch, Michael Heide, Vindi Jurinovic, MSc, Monika Szczepanowski, Wolfram Klapper, Abner Louissaint, Jr., MD PhD, Christina Ludwig, Sebastian Bultmann, Heinrich Leonhardt, Sebastian Eustermann, Karl-Peter Hopfner, Wolfgang Hiddemann, MD PhD, Michael von Bergwelt, Christian Steidl, MD, Robert Kridel, MDMPH,PhD, David M Weinstock, Marc Schmidt-Supprian, Menyhárt B Sárosi, Verena Passerini, Josef Mautner, Oliver Weigert
Journal: Blood
Blood (2019) 134 (Supplement_1): 657.
https://doi.org/10.1182/blood-2019-122663
Published: 2019
Journal Articles

Risk Factors and Outcomes of Patients with Follicular Lymphoma Who Had Histologic Transformation at First Progression after First-Line Immunochemotherapy in the Gallium Study

Carla Casulo, Michael Herold, MD, Wolfgang Hiddemann, MD PhD, Sunil Iyengar, MD, Robert E. Marcus, FRCP, John F. Seymour, MBBS, PhD FRACP, Aino Launonen, MSc, Andrea Knapp, PhD, Tina G Nielsen, MD PhD, Farheen Mir, MBBS, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5268.
https://doi.org/10.1182/blood-2019-123466
Published: 2019
Journal Articles

A Multistate Survival Analysis for Patients with Follicular Lymphoma (FL) Using 13 First-Line Randomized Trials from FL Analysis of Surrogate Hypothesis (FLASH) Group

Caglar Caglayan, MS,PhD, Jesse Dixon, Statistician, MS, Anna Wall, Statistician, Gilles A. Salles, MD PhD, Eva Hoster, PhD, Wolfgang Hiddemann, MD PhD, Michael Herold, MD, Franck Morschhauser, MD PhD, Catherine Sebban, MD, Anton Hagenbeek, MD PhD, Robert Marcus, MD, Howard Hochster, MD, Mathias J Rummel, MD PhD, Eva Kimby, MD PhD, Umberto Vitolo, Bruce A. Peterson, MD, Emmanuel Gyan, MD PhD, Marco Ladetto, MD, Charles Yves Foussard, MD, Michele Ghielmini, MD, Tina G Nielsen, MD PhD, Kenneth Foon, MD, Qian Shi, PhD, Christopher R. Flowers, MD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2812.
https://doi.org/10.1182/blood-2019-122328
Published: 2019
Journal Articles

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

Sebastian Vosberg, Paul Kerbs, MSc, Vindi Jurinovic, MSc, Klaus H. Metzeler, MD, Susanne Amler, PhD, Cristina Sauerland, Dennis Görlich, PhD, Wolfgang E. Berdel, MD, Jan Braess, MD, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, MD, Tobias Herold, MD, Philipp A. Greif, MD PD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2715.
https://doi.org/10.1182/blood-2019-130047
Published: 2019
Journal Articles

Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk Stratification

Diego Chacon, PhD, Ali Braytee, PhD, Yizhou Huang, PhD, Julie Thoms, PhD, Shruthi Subramanian, BSc, Maria Cristina Sauerland, Stefan K. Bohlander, MD, Jan Braess, MD, Bernhard J. Wörmann, MD, Wolfgang E. Berdel, MD, Wolfgang Hiddemann, MD PhD, Bogdan Gabrys, PhD, Klaus H. Metzeler, MD, Tobias Herold, MD, John Pimanda, MBBS, PhD, Dominik Beck, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1397.
https://doi.org/10.1182/blood-2019-129519
Published: 2019
Journal Articles

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Georg Leubolt, MSc, Paul Kerbs, MSc, Johannes Bagnoli, Wolfgang Hiddemann, MD PhD, Wolfgang Enard, PhD, Sebastian Theurich, MD, Philipp A. Greif, MD PD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1453.
https://doi.org/10.1182/blood-2019-128378
Published: 2019
Journal Articles

GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response

Georg Leubolt, MSc, Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Paul Kerbs, MSc, Monica Cusan, MD, Johannes Bagnoli, Wolfgang Enard, PhD, Wolfgang Hiddemann, MD PhD, Christian Wichmann, MD, Gunnar Schotta, PhD, Philipp A. Greif, MD PD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1459.
https://doi.org/10.1182/blood-2019-128218
Published: 2019
Journal Articles

Identification of Novel Targets for Antibody or Chimeric Antigen Receptor (CAR) Based Immunotherapy in AML: Characterizing the Surfaceome from Primary Patient Samples

Thomas Koehnke, MD, Liu Xilong, Sascha Haubner, MD, Christina Krupka, PhD, Victor Solis-Mezarino, Franz Herzog, PhD, Wolfgang Hiddemann, MD PhD, Marion S. Subklewe, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3968.
https://doi.org/10.1182/blood.V130.Suppl_1.3968.3968
Published: 2017
Journal Articles

Influence of Baseline Disease Characteristics and Exposure to Obinutuzumab on Clinical Outcome in Patients with Previously Untreated Advanced Follicular Lymphoma Treated with Obinutuzumab-Based Immunochemotherapy in the GALLIUM Trial

Candice Jamois, Ekaterina Gibiansky, Leonid Gibiansky, Vincent Buchheit, Pauline Baumlin, Denis Sahin, Guillaume Cartron, Robert Marcus, Wolfgang Hiddemann, MD PhD, John F Seymour, MBBS, PhD, Jonathan C Strefford, PhD, Georgina Meneses-Lorente, Nicolas Frey, Günter Fingerle-Rowson
Journal: Blood
Blood (2017) 130 (Supplement 1): 3848.
https://doi.org/10.1182/blood.V130.Suppl_1.3848.3848
Published: 2017
Journal Articles

Low Peripheral Blood NK Cell Count Is Associated with Worse Clinical Outcome in Patients with Follicular Lymphoma (FL) and Diffuse Large B-Cell Lymphoma (DLBCL) Treated with Immunochemotherapy: Results from the Frontline Phase 3 GALLIUM and GOYA Trials

Magdalena Klanova, MD, Mikkel Z. Oestergaard, Marek Trněný, MD PhD, Wolfgang Hiddemann, MD PhD, Robert Marcus, Laurie H. Sehn, MDMPH, Umberto Vitolo, MD, Alexandra Bazeos, Valentin Goede, MD, Harald Zeuner, Andrea Knapp, Denis Sahin, Nathalie Danesi, Christopher Bolen, Susan Robson, Jeffrey M. Venstrom, Tina Nielsen, Günter Fingerle-Rowson
Journal: Blood
Blood (2017) 130 (Supplement 1): 727.
https://doi.org/10.1182/blood.V130.Suppl_1.727.727
Published: 2017
Journal Articles

Midostaurin Reduces Bite® Mediated Cytotoxicity Against Acute Myeloid Leukemia

Bettina Lindl, Christina Krupka, PhD, Tara Chapman-Arvedson, Roman Kischel, MD, Peter Kufer, MD, Sascha Haubner, MD, Felix S. Lichtenegger, MD, Thomas Koehnke, MD, Klaus H. Metzeler, MD, Nikola Konstandin, PhD, Karsten Spiekermann, Wolfgang Hiddemann, MD PhD, Marion Subklewe, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2656.
https://doi.org/10.1182/blood.V130.Suppl_1.2656.2656
Published: 2017
Journal Articles

The Mutational Landscape and Immune Microenvironment of Primary Intestinal Follicular Lymphoma (PIFL)

Johannes Hellmuth, MD, Abner Louissaint, MD PhD, Monika Szczepanowski, PhD, Sarah Häbe, MD, Alessandro Pastore, MD, Annette M. Staiger, PhD, Sylvia Hartmann, Robert Kridel, Matthew D. Ducar, MS, Peter Koch, MD, Martin Dreyling, MD PhD, Martin-Leo Hansmann, MD, German Ott, MD, Andreas Rosenwald, MD, Randy D. Gascoyne, MD, David M. Weinstock, MD, Wolfgang Hiddemann, MD PhD, Wolfram Klapper, MD, Oliver Weigert, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2735.
https://doi.org/10.1182/blood.V130.Suppl_1.2735.2735
Published: 2017
Journal Articles

Minimal Residual Disease (MRD) Detection By Flow Cytometry during Aplasia and Post-Induction Is an Independent Prognostic Parameter for Relapse-Free Survival in AML

Veit Bücklein, MD, Thomas Koehnke, MD, Sandra Rechkemmer, Frauke Schnorfeil, PhD, Stephanie Schneider, PhD, Maja Rothenberg-Thurley, PhD, Klaus H. Metzeler, MD, Cristina Sauerland, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, Marion S. Subklewe, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5081.
https://doi.org/10.1182/blood.V130.Suppl_1.5081.5081
Published: 2017
Journal Articles

Early Disease Progression Predicts Poorer Survival in Patients with Follicular Lymphoma (FL) in the GALLIUM Study

Aino Launonen, Wolfgang Hiddemann, MD PhD, Ulrich Duenzinger, Günter Fingerle-Rowson, Tina Nielsen, Robert Marcus
Journal: Blood
Blood (2017) 130 (Supplement 1): 1490.
https://doi.org/10.1182/blood.V130.Suppl_1.1490.1490
Published: 2017
Journal Articles

Standardized IGH-Based Next-Generation Sequencing for MRD Detection in Follicular Lymphoma

Christiane Pott, MD, PhD, Henrik Knecht, PhD, Arved Herzog, Elisa Genuardi, Michael Unterhalt, MD PhD, Barbara Mantoan, Irene Dogliotti, Wolfgang Hiddemann, MD PhD, Mario Boccadoro, Dietrich Herrmann, Michael Kneba, MD, Anton W Langerak, Nikos Darzentas, Patricia Groenen, Monika Brüggemann, MD, Eva Hoster, Marco Ladetto, Simone Ferrero
Journal: Blood
Blood (2017) 130 (Supplement 1): 1491.
https://doi.org/10.1182/blood.V130.Suppl_1.1491.1491
Published: 2017
Journal Articles

Steroids Abrogate BiTE ® Antibody Construct-Mediated Cytotoxicity in Primary AML Cells

Christina Krupka, Bettina Lindl, Thomas Köhnke, MD, Julia Platzer, Lavinia Pachzelt, Felix S Lichtenegger, MD, Torben Altmann, Peter Kufer, MD, Roman Kischel, MD, Wolfgang Hiddemann, MD, PhD, Marion Subklewe, MD
Journal: Blood
Blood (2016) 128 (22): 3940.
https://doi.org/10.1182/blood.V128.22.3940.3940
Published: 2016
Journal Articles

Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients

Katrin Reiter, MSc, Max Hubmann, MD, Egor Harin, Sebastian Vosberg, Kathrin Bräundl, Bianka Ksienzyk, Stephanie Schneider, PhD, Annika Maria Dufour, PhD, Evelyn Zellmeier, Stefan K. Bohlander, MD, Christina Sauerland, Dipl.-Math, Wolfgang E Berdel, MD, Bernhard J Wörmann, MD, Thomas Büchner, MD, Jan Braess, MD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD
Journal: Blood
Blood (2016) 128 (22): 1682.
https://doi.org/10.1182/blood.V128.22.1682.1682
Published: 2016
Journal Articles

Obinutuzumab-Based Induction and Maintenance Prolongs Progression-Free Survival (PFS) in Patients with Previously Untreated Follicular Lymphoma: Primary Results of the Randomized Phase 3 GALLIUM Study

Robert E Marcus, Andrew J Davies, FRCP PhD, Kiyoshi Ando, Wolfram Klapper, MD, Stephen Opat, MD, Carolyn J Owen, Elizabeth H Phillips, Randeep Sangha, Rudolf Schlag, John F Seymour, William Townsend, Marek Trněný, Michael K Wenger, Günter Fingerle-Rowson, Kaspar Rufibach, Tom Moore, Michael Herold, Wolfgang Hiddemann, MD
Journal: Blood
Blood (2016) 128 (22): 6.
https://doi.org/10.1182/blood.V128.22.6.6
Published: 2016
Journal Articles

Outcomes for Elderly Patients (pts) with Follicular Lymphoma (FL) Using Individual Patient Data (IPD) from 5922 Pts in 18 Randomized Controlled Trials (RCTs): a Follicular Lymphoma Analysis of Surrogate Hypothesis (FLASH) Group Study

Christopher Flowers, MDMS, Fang-Shu Ou, PhD, Qian Shi, PhD, Eva Hoster, PhD, Bruce A. Peterson, MD, Howard S. Hochster, MD, Pauline Brice, MD, Marco Ladetto, MD, Wolfgang Hiddemann, MD, Robert E Marcus, Eva Kimby, MD PhD, Michael Herold, Sabine De Bedout, MD MPH, Tina Nielsen, Franck Morschhauser, Mathias Rummel, MD PhD, Anton Hagenbeek, MD PhD, Umberto Vitolo, Gilles A. Salles, Daniel Sargent, PhD
Journal: Blood
Blood (2016) 128 (22): 1102.
https://doi.org/10.1182/blood.V128.22.1102.1102
Published: 2016