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Xinliang Mao, MD, PhD
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Journal Articles

PCT3, a Combination of Active Steroidal Saponins from the Paris Forrestii (Takht.) H. Li, Displays Potent Activity Against Acute Myeloid Leukemia By Suppressing the PBX1/RNF6/AKT/mTOR Signaling Pathway

Qin Lu, MD, Yunjing Zheng, MD, Yuehu Wang, PhD, Jian Pan, PhD, Xinliang Mao, MD PhD, Shaoyan Hu, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2533.
https://doi.org/10.1182/blood.V130.Suppl_1.2533.2533
Published: 2017
Journal Articles

Ikaros Family Zinc Finger 1 Mutation Is a Poor Prognosis Factor of Adult B Cell Acute Lymphoblastic Leukemia

Shanhao Tang, Hongjie Shen, Xinliang Mao, MD PhD, Haiping Dai, Xiaming Zhu, Shengli Xue, Zixuan Ding, Jing Lu, Depei Wu, MD, XiaoWen Tang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5117.
https://doi.org/10.1182/blood.V130.Suppl_1.5117.5117
Published: 2017
Journal Articles

Loss of Autophagy Leads to Megakaryocytes Differentiation Failure and Defective Platelets Function

Yan Cao, BS, Jinyang Cai, MS, Xin Li, BS, Yixuan Fang, BS, Suping Zhang, MD PhD, Na Yuan, BS, Xinliang Mao, MD PhD, Jianrong Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 4148.
https://doi.org/10.1182/blood.V124.21.4148.4148
Published: 2014
Journal Articles

Autophagy Collaborates with Ubiquitination to Down-Regulate Oncoprotein E2A/Pbx1 in B Cell Acute Lymphoblastic Leukemia

Suping Zhang, MD PhD, Lin Song, BS, Na Yuan, BS, Weiwei Lin, MS, Yan Cao, BS, Fei Xu, MS, Yixuan Fang, BS, Zheng Wang, BS, Xin Li, BS, Zhijian Wang, MS, Jinyang Cai, MS, Wenli Zhao, MD PhD, Shaoyan Hu, MD PhD, Suning Chen, MD PhD, Xinliang Mao, MD PhD, Jianrong Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 5276.
https://doi.org/10.1182/blood.V124.21.5276.5276
Published: 2014
Journal Articles

Bafilomycin A1 Targets Both Autophagy and Apoptosis Pathways in Pediatric t(1;19) Pre-B Acute Lymphoblastic Leukemia Cells

Na Yuan, BS, Lin Song, BS, Suping Zhang, MD PhD, Weiwei Lin, MS, Yan Cao, BS, Fei Xu, MS, Yixuan Fang, BS, Zheng Wang, BS, Zhijian Wang, MS, Xin Li, BS, Jinyang Cai, MS, Yi Zhang, PhD, Wenli Zhao, MD PhD, Shaoyan Hu, MD PhD, Suning Chen, MD PhD, Xinliang Mao, MD PhD, Jianrong Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 3699.
https://doi.org/10.1182/blood.V124.21.3699.3699
Published: 2014
Journal Articles

Targeting The PI3K/AKT Pathway To Inhibit Platelet Activation and Thrombus Formation

Wenxiu Yi, BS, Wei Li, MS, Lijie Ren, MS, Xinliang Mao, MD, PhD, Li Zhu, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3513.
https://doi.org/10.1182/blood.V122.21.3513.3513
Published: 2013
Journal Articles

The Proteasomal Inhibitor Clioquinol Induces Apoptosis in Leukemia and Myeloma Cells by Inhibiting Histone Deacetylase Activity.

Biyin Cao, MD, PhD, Mingyun Shen, Mr., Depei Wu, Jianhong Du, MD, Jingyu Zhu, Suning Chen, Aining Sun, Xiaowen Tang, MD, PhD, Zhuan Xu, Yan Kong, MD. PhD, Xinliang Mao, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2449.
https://doi.org/10.1182/blood.V120.21.2449.2449
Published: 2012
Journal Articles

Clioquinol Arrests Cell Cycle at G1 Phase and Triggers Intrinsic Apoptosis In Myeloma and Leukemia Cells by Inhibiting Histone Deacetylases

Biyin Cao, Tingjun Hou, PhD, Suning Chen, Depei Wu, Aining Sun, Huiying Qiu, Wenjie Wang, Aaron Schimmer, MD, PhD, Xinliang Mao, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1836.
https://doi.org/10.1182/blood.V116.21.1836.1836
Published: 2010
Journal Articles

A Small Molecule Inhibitor of D-Cyclin Transactivation Displays Preclinical Efficacy in Myeloma and Leukemia.

Xinliang Mao, MD, PhD, Tabitha E Wood, PhD, Rose Hurren, Jiefei Tong, PhD, Xiaoming Wang, Paul A. Spagnuolo, PhD, Neil MacLean, Michael F. Moran, PhD, Alessandro Datti, Jeff Wrana, PhD, Robert A. Batey, PhD, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2036.
https://doi.org/10.1182/blood.V114.22.2036.2036
Published: 2009
Journal Articles

A Novel Chromene-Based Pan-PI3 Kinase Inhibitor Displays Preclinical Activity in Leukemia and Myeloma.

Xinliang Mao, MD, PhD, Tabitha W. Wood, PhD, Xiaoming Wang, PhD, Johnathan St-Germain, BSc, Michael F. Moran, PhD, Alessandro Datti, PhD, Jeff Wrana, PhD, Robert A. Batey, PhD, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1605.
https://doi.org/10.1182/blood.V112.11.1605.1605
Published: 2008
Journal Articles

Identification of a Potent Natural Triterpenoid Inhibitor of Proteosome Chymotrypsin-Like Activity and NF-κB with Specific Anti-Myeloma Activity in Vitr o and in Vivo

Rodger E. Tiedemann, MBChB, PhD, FRACP, FRCPA, Jonathan J Keats, PhD, Jessica Schmidt, BS, Chang-Xin Shi, Yuan X Zhu, PhD, Xinliang Mao, MD, PhD, Aaron D. Schimmer, Keith Stewart, MD
Journal: Blood
Blood (2008) 112 (11): 3679.
https://doi.org/10.1182/blood.V112.11.3679.3679
Published: 2008
Journal Articles

A High Throughput Seeking Myeloma Therapeutics Identifies Glucocorticoids as Inhibitors of c-Maf-Dependent Transactivation of Cyclin D2.

Xinliang Mao, MD, PhD, A. Keith Stewart, MD, Alessandro Datti, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 3384.
https://doi.org/10.1182/blood.V106.11.3384.3384
Published: 2005