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Journal Articles

Outcomes of a Clinician-Directed Protocol for Discontinuation of Complement Inhibition Therapy in Atypical Hemolytic Uremic Syndrome

Noor Dhaliwal, Sarah Hussain, Harshvardhan Upreti, Evan M Braunstein, MDPhD, Xuan Yuan, MD MSc, Alison R. Moliterno, MD, Robert Brodsky, MD, Shruti Chaturvedi, MBBS,MS

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-142965

Published: 2020

Journal Articles

Defects in Sialic Acid Biosynthesis Cause Dysregulation of the Alternative Pathway of Complement

Hang Chen, Luyi Peng, Jia Yu, BS, Xuan Yuan, MD MSc, Shruti Chaturvedi, MBBS,MS, Robert Brodsky, MD, Evan M Braunstein, MDPhD

Blood (2020) 136 (Supplement 1): 3.

https://doi.org/10.1182/blood-2020-141289

Published: 2020

Journal Articles

Rare Germline Mutations in Complement Regulatory Genes Make the Antiphospholipid Syndrome Catastrophic

Shruti Chaturvedi, MBBS, MS, Evan M Braunstein, MD PhD, Xuan Yuan, MD MSc, Hang Chen, Ravi Kumar Alluri, PhD, Michael B. Streiff, MD, Michelle Petri, MD MPH, Mark Crowther, MD MSc, FRCPC, Keith R McCrae, MD, Robert A. Brodsky, MD

Blood (2019) 134 (Supplement_1): 4.

https://doi.org/10.1182/blood-2019-129115

Published: 2019

Journal Articles

An Alternative Pathway Specific Flow Cytometric Assay to Detect Complement Activation in Atypical Hemolytic Uremic Syndrome (aHUS)

Jia Yu, Xuan Yuan, MD MSc, Kang Zhou, Daniel White, Samuel A. Merrill, MD PhD, Robert A. Brodsky, MD

Blood (2018) 132 (Supplement 1): 3748.

https://doi.org/10.1182/blood-2018-99-119445

Published: 2018

Journal Articles

Chronic Kidney Disease, Hypertension and Cardiovascular Sequelae during Long Term Follow up of Adults with Atypical Hemolytic Uremic Syndrome

Shruti Chaturvedi, MBBS, MS, Alison R. Moliterno, MD, Samuel A. Merrill, MD PhD, Evan M Braunstein, MD PhD, Xuan Yuan, MD MSc, Christopher John Sperati, MD, Gebran Khneizer, Robert A. Brodsky, MD

Blood (2018) 132 (Supplement 1): 3754.

https://doi.org/10.1182/blood-2018-99-119999

Published: 2018

Journal Articles

In Vitro Combination Studies of ACH-4471 with Eculizumab to Assess a Potential "Switch" Treatment Approach for Paroxysmal Nocturnal Hemoglobinuria

Dharaben Patel, MS, Jane A Thanassi, BS, Guangwei Yang, PhD, Xuan Yuan, MD MSc, Robert A. Brodsky, MD, Mingjun Huang, PhD, Steven D Podos, PhD

Blood (2017) 130 (Supplement 1): 2198.

https://doi.org/10.1182/blood.V130.Suppl_1.2198.2198

Published: 2017

Journal Articles

β-2-Glycoprotein Antibodies Activate the Alternative Pathway of Complement in Antiphospholipid Antibody Syndrome

Andrea C. Baines, MD PhD, Xuan Yuan, MD MSc, Eleni Gavriilaki, MD PhD, Alexander J. Ambinder, MD MPH, Alka Jain, PhD, Neal S. Fedarko, PhD, C. John Sperati, MD MHS, Alison R. Moliterno, MD, Rakhi P. Naik, MD MHS, Michael Streiff, MD, Wei Fu, MS, Michelle Petri, MD MPH, Robert A. Brodsky, MD

Blood (2016) 128 (22): 3818.

https://doi.org/10.1182/blood.V128.22.3818.3818

Published: 2016

Journal Articles

Evaluation of Bacteria-Mediated Potential "Bystander" Hemolysis of PNH RED CELLS I n Vitro : NO Evidence of Significant Complement Classical or Lectin Pathway-Mediated Hemolysis Induced by Microorganisms

Xuan Yuan, MD MSc, Guangwei Yang, PhD, Jane A Thanassi, Manuel D Galvan, PhD, Steven D Podos, PhD, Mingjun Huang, PhD, Robert A. Brodsky, MD

Blood (2016) 128 (22): 2431.

https://doi.org/10.1182/blood.V128.22.2431.2431

Published: 2016

Journal Articles

Direct Evidence of Complement Activation in HELLP Syndrome: A Link to Atypical Hemolytic Uremic Syndrome

Eleni Gavriilaki, MD, Arthur Vaught, Nancy Heuppchen, Karin Blakemore, Xuan Yuan, MD MSc, Sara Seifert, Sara York, Robert A. Brodsky, MD

Blood (2015) 126 (23): 1047.

https://doi.org/10.1182/blood.V126.23.1047.1047

Published: 2015

Journal Articles

Modified Ham Test Distinguishes aHUS from TTP and Predicts Response to Eculizumab

Eleni Gavriilaki, MD, Xuan Yuan, MD MSc, Zhaohui Ye, PhD, Michael B. Streiff, MD, Thomas S Kickler, MD, Alison R Moliterno, MD, John Sperati, MD, Robert A. Brodsky, MD

Blood (2015) 126 (23): 103.

https://doi.org/10.1182/blood.V126.23.103.103

Published: 2015

Journal Articles

Small Molecule Factor D Inhibitors Block Complement Activation in Paroxysmal Nocturnal Hemoglobinuria and Atypical Hemolytic Uremic Syndrome

Eleni Gavriilaki, MD, Jane A Thanassi, BS, Guangwei Yang, Xuan Yuan, MD MSc, Mngjun Huang, Robert A. Brodsky, MD

Blood (2015) 126 (23): 275.

https://doi.org/10.1182/blood.V126.23.275.275

Published: 2015

NARROW

Outcomes of a Clinician-Directed Protocol for Discontinuation of Complement Inhibition Therapy in Atypical Hemolytic Uremic Syndrome

Defects in Sialic Acid Biosynthesis Cause Dysregulation of the Alternative Pathway of Complement

Rare Germline Mutations in Complement Regulatory Genes Make the Antiphospholipid Syndrome Catastrophic

An Alternative Pathway Specific Flow Cytometric Assay to Detect Complement Activation in Atypical Hemolytic Uremic Syndrome (aHUS)

Chronic Kidney Disease, Hypertension and Cardiovascular Sequelae during Long Term Follow up of Adults with Atypical Hemolytic Uremic Syndrome

In Vitro Combination Studies of ACH-4471 with Eculizumab to Assess a Potential "Switch" Treatment Approach for Paroxysmal Nocturnal Hemoglobinuria

β-2-Glycoprotein Antibodies Activate the Alternative Pathway of Complement in Antiphospholipid Antibody Syndrome

Evaluation of Bacteria-Mediated Potential "Bystander" Hemolysis of PNH RED CELLS I n Vitro : NO Evidence of Significant Complement Classical or Lectin Pathway-Mediated Hemolysis Induced by Microorganisms

Direct Evidence of Complement Activation in HELLP Syndrome: A Link to Atypical Hemolytic Uremic Syndrome

Modified Ham Test Distinguishes aHUS from TTP and Predicts Response to Eculizumab

Small Molecule Factor D Inhibitors Block Complement Activation in Paroxysmal Nocturnal Hemoglobinuria and Atypical Hemolytic Uremic Syndrome

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American Society of Hematology

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ASH Publications

American Society of Hematology

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