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Journal Articles

Downregulation of Morrbid in Tet2-Deficient Preleukemic Cells Overcomes Resistance to Inflammatory Stress and Mitigates Clonal Hematopoiesis

Zhigang Cai, PhD, Jonathan Kotzin, Baskar Ramdas, PhD, Sisi Chen, Sai Nelanuthala, Lakshmi Reddy Palam, PhD, Ruchi Pandey, Raghuveer Mali, PhD, Yan Liu, PhD, Mark R. Kelley, George Sandusky, DVM, PhD, Morvarid Mohseni, Adam Williams, Jorge Henao-Mejia, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 1288.

https://doi.org/10.1182/blood-2018-99-116703

Published: 2018

Journal Articles

Gain of Function Mutant p53 Drives Clonal Hematopoiesis and the Pathogenesis of Myelodysplastic Syndromes

Sisi Chen, Hao Yu, PhD, Rui Gao, PhD, Sarah C. Nabinger, PhD, Michihiro Kobayashi, MD PhD, Chonghua Yao, Linsey Mayo, PhD, Reuben Kapur, PhD, Mervin C. Yoder, MD, Hal E. Broxmeyer, PhD, Zhonghua Gao, Yan Liu, PhD

Blood (2017) 130 (Supplement 1): 2489.

https://doi.org/10.1182/blood.V130.Suppl_1.2489.2489

Published: 2017

Journal Articles

PRL2 Phosphatase Is a Key Mediator of Oncogenic Cytokine Signaling in Leukemia Stem Cells

Michihiro Kobayashi, MD PhD, Yunpeng Bai, PhD, Sisi Chen, BS, Sarah C Nabinger, PhD, Chonghua Yao, MD, Zhong-Yin Zhang, PhD, Yan Liu, PhD

Blood (2016) 128 (22): 724.

https://doi.org/10.1182/blood.V128.22.724.724

Published: 2016

Journal Articles

Polycomb Repressive Complex 1 Enhances HSC Self-Renewal through Repressing the Canonical Wnt Signaling Pathway

Sisi Chen, BS, Xicheng Liu, Rui Gao, PhD, Michihiro Kobayashi, MD PhD, Hao Yu, PhD, Chonghua Yao, MD, Zhijian Qian, PhD, Rongwen Xi, PhD, Yan Liu, PhD

Blood (2015) 126 (23): 2378.

https://doi.org/10.1182/blood.V126.23.2378.2378

Published: 2015

Journal Articles

S6K1 Regulates Self-Renewal of Leukemia Initiating Cells and Normal Hematopoietic Stem Cells

Joydeep Ghosh, MSc, Anindya Chatterjee, MS,PhD, Baskar Ramdas, PhD, Michihiro Kobayashi, MD PhD, Peilin Ma, MD PhD, Yan Liu, PhD, David Plas, PhD, Reuben Kapur, PhD

Blood (2015) 126 (23): 442.

https://doi.org/10.1182/blood.V126.23.442.442

Published: 2015

Journal Articles

Mutant p53 Drives the Development of Pre-Leukemic Hematopoietic Stem Cells through Modulating Epigenetic Regulators

Sarah C Nabinger, PhD, Michihiro Kobayashi, MD PhD, Rui Gao, PhD, Sisi Chen, BS, Chonghua Yao, MD, Feng-Chun Yang, MD PhD, Yan Liu, PhD

Blood (2015) 126 (23): 307.

https://doi.org/10.1182/blood.V126.23.307.307

Published: 2015

Journal Articles

Gain-of-Function Mutant p53 Enhances Hematopoietic Stem Cell Self-Renewal

Sisi Chen, Hao Yu, PhD, Michihiro Kobayashi, MDPhD, Rui Gao, PhD, H. Scott Boswell, MD, Yan Liu, PhD

Blood (2014) 124 (21): 260.

https://doi.org/10.1182/blood.V124.21.260.260

Published: 2014

Journal Articles

Modulation in the Expression of p70S6 Kinase Impairs the Engraftment and Self-Renewal of Hematopoietic Stem Cells

Joydeep Ghosh, MS, Baskar Ramdas, PhD, Anindya Chatterjee, MS,PhD, Peilin Ma, MD PhD, Michihiro Kobayashi, MDPhD, Raghuveer Mali, PhD, Yan Liu, PhD, David R. Plas, PhD, Reuben Kapur, PhD

Blood (2014) 124 (21): 252.

https://doi.org/10.1182/blood.V124.21.252.252

Published: 2014

Journal Articles

Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib in Acute Myeloid Leukemia with FLT3-ITD Mutation or Monosomy 5, 7, or Complex Cytogenetics

Mohammad Abu Zaid, MBBS, H. Scott Boswell, MD, Larry D. Cripe, MD, Yan Liu, PhD, Jill Weisenbach, BS, Hamid Sayar, MD MS

Blood (2014) 124 (21): 976.

https://doi.org/10.1182/blood.V124.21.976.976

Published: 2014

Journal Articles

PRL2 Phosphatase Regulate Early Stage T-Cell Development through Fine-Tuning SCF/Kit Signaling

Kobayashi Michihiro, MD PhD, Yunpeng Bai, PhD, Momoko Yoshimoto, MD PhD, Rui Gao, PhD, Chen Sisi, Yuanshu Dong, PhD, Zhon-Yin Zhang, PhD, Yan Liu, PhD

Blood (2014) 124 (21): 1569.

https://doi.org/10.1182/blood.V124.21.1569.1569

Published: 2014

Journal Articles

PRL2 Maintains Hematopoietic Stem and Progenitor Cells Through Regulating SCF/KIT Signaling

Michihiro Kobayashi, MD, PhD, Yuanshu Dong, Ph.D., Hao Yu, Ph.D., Yunpeng Bai, Sisi Chen, Rui Gao, PhD, Mervin C. Yoder, MD, Reuben Kapur, PhD, Zhong-Yin Zhang, PhD, Yan Liu, PhD

Blood (2013) 122 (21): 3674.

https://doi.org/10.1182/blood.V122.21.3674.3674

Published: 2013

Journal Articles

BMI1 Promotes Erythropoiesis Through Regulating Ribosome Biogenesis

Rui Gao, PhD, Sisi Chen, Michihiro Kobayashi, MD, PhD, Mervin C. Yoder, MD, Reuben Kapur, PhD, Xiaofan Zhu, MD/PhD, Yan Liu, PhD

Blood (2013) 122 (21): 3707.

https://doi.org/10.1182/blood.V122.21.3707.3707

Published: 2013

Journal Articles

High-Risk AML, Including Flt3ITD+, Exhibits Resistance To Conventional Cytarabine Induction Associated With Diminished ENT1 and p16INK Expression: Evidence For Epigenetic Repression and HDAC Inhibitor Modulated De-Repression

H. Scott Boswell, MD, Sushil Gupta, Rui Gao, PhD, Katie J Sargent, Larry D. Cripe, MD, Mehdi Nassiri, MD, Hamid Sayar, MD, Yan Liu, PhD

Blood (2013) 122 (21): 2525.

https://doi.org/10.1182/blood.V122.21.2525.2525

Published: 2013

Journal Articles

Regulation of Hematopoietic Stem Cell Quiescence - A Novel Role for p53.

Yan Liu, PhD, Shannon E. Elf, MS, Yasuhiko Miyata, Ph.D., Goro Sashida, Ph.D., Anthony D. Deblasio, MS, Yuhui Liu, Ph.D., Andrew Koff, Ph.D., Stephen D. Nimer, MD

Blood (2007) 110 (11): 92.

https://doi.org/10.1182/blood.V110.11.92.92

Published: 2007

Journal Articles

Deleterious Roles of the KIR Ligand Mismatch on Acute Graft Versus Host Disease in Unmanipulated HLA-Mismatched/Haploidentical Blood and Marrow Transplantation.

Xiao Jun Huang, MD, Xiang Yu Zhao, PhD., Dai Hong Liu, MD., Kai Yan Liu, PhD., Lan Ping Xu, MD., Yu Hong Chen, MD., Wei Han, MD.

Blood (2006) 108 (11): 2874.

https://doi.org/10.1182/blood.V108.11.2874.2874

Published: 2006

Journal Articles

Genetic Uncoupling of the Regulation of Hematopoietic Stem Cell Quiescence and Self-Renewal.

Yan Liu, PhD, Yasuhiko Miyata, Ph.D., Goro Sashida, Ph.D., Anthony Debalsio, MS, Yuhui Liu, Ph.D., Andrew Koff, Ph.D., Stephen D. Nimer, M.D.

Blood (2006) 108 (11): 1347.

https://doi.org/10.1182/blood.V108.11.1347.1347

Published: 2006

Journal Articles

Antigen-Dependent Suppression of Graft Versus Host Disease by Foxp3- Induced Regulatory T Cells in Transplantation.

Michael H. Albert, MD, Yan Liu, PhD, Claudio Anasetti, MD, Xue-Zhong Yu, MD

Blood (2005) 106 (11): 1302.

https://doi.org/10.1182/blood.V106.11.1302.1302

Published: 2005

Journal Articles

Identification of a MEF Gene Mutation in a Familial Hemophagocytic Lymphohistiocytosis Patient That Decreases MEF Transcriptional Activity.

H. Daniel Lacorazza, PhD, Serena Lopiccolo, MD, Eric Rubenstein, MD, Yan Liu, PhD, Juliana Nunes, B.Sc, Henrik Hasle, MD, Bengt Fadeel, MD, Kim Ericson, MDPhD, Jan-Inge Henter, MD, Stephen D. Nimer, MD

Blood (2005) 106 (11): 3013.

https://doi.org/10.1182/blood.V106.11.3013.3013

Published: 2005

NARROW

Downregulation of Morrbid in Tet2-Deficient Preleukemic Cells Overcomes Resistance to Inflammatory Stress and Mitigates Clonal Hematopoiesis

Gain of Function Mutant p53 Drives Clonal Hematopoiesis and the Pathogenesis of Myelodysplastic Syndromes

PRL2 Phosphatase Is a Key Mediator of Oncogenic Cytokine Signaling in Leukemia Stem Cells

Polycomb Repressive Complex 1 Enhances HSC Self-Renewal through Repressing the Canonical Wnt Signaling Pathway

S6K1 Regulates Self-Renewal of Leukemia Initiating Cells and Normal Hematopoietic Stem Cells

Mutant p53 Drives the Development of Pre-Leukemic Hematopoietic Stem Cells through Modulating Epigenetic Regulators

Gain-of-Function Mutant p53 Enhances Hematopoietic Stem Cell Self-Renewal

Modulation in the Expression of p70S6 Kinase Impairs the Engraftment and Self-Renewal of Hematopoietic Stem Cells

Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib in Acute Myeloid Leukemia with FLT3-ITD Mutation or Monosomy 5, 7, or Complex Cytogenetics

PRL2 Phosphatase Regulate Early Stage T-Cell Development through Fine-Tuning SCF/Kit Signaling

PRL2 Maintains Hematopoietic Stem and Progenitor Cells Through Regulating SCF/KIT Signaling

BMI1 Promotes Erythropoiesis Through Regulating Ribosome Biogenesis

High-Risk AML, Including Flt3ITD+, Exhibits Resistance To Conventional Cytarabine Induction Associated With Diminished ENT1 and p16INK Expression: Evidence For Epigenetic Repression and HDAC Inhibitor Modulated De-Repression

Regulation of Hematopoietic Stem Cell Quiescence - A Novel Role for p53.

Deleterious Roles of the KIR Ligand Mismatch on Acute Graft Versus Host Disease in Unmanipulated HLA-Mismatched/Haploidentical Blood and Marrow Transplantation.

Genetic Uncoupling of the Regulation of Hematopoietic Stem Cell Quiescence and Self-Renewal.

Antigen-Dependent Suppression of Graft Versus Host Disease by Foxp3- Induced Regulatory T Cells in Transplantation.

Identification of a MEF Gene Mutation in a Familial Hemophagocytic Lymphohistiocytosis Patient That Decreases MEF Transcriptional Activity.

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American Society of Hematology

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American Society of Hematology

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