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Yang Yang, MD, PhD
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Journal Articles

Increased Expression of EZH2 Is Associated with Inferior Survival in Primary Central Nervous System Diffuse Large B-Cell Lymphoma

Briana Gibson, MD, Rahul Matnani, MBBS, PhD, Zheng Ping, MD, Balabhadrapatruni VSK Chakravarthi, Yang Yang, MD PhD, Sooryanarayana Varambally, PhD, Denise Peker, MD
Journal: Blood
Blood (2016) 128 (22): 4216.
https://doi.org/10.1182/blood.V128.22.4216.4216
Published: 2016
Journal Articles

Osteocyte Apoptosis Attracts Myeloma Cells to Bone and Supports Progression through Regulation of the Bone Marrow Microenvironment

Timothy N. Trotter, Mary Fok, Justin T. Gibson, Deniz Peker, MD, Amjad Javed, MSc, PhD, Yang Yang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 484.
https://doi.org/10.1182/blood.V128.22.484.484
Published: 2016
Journal Articles

Myeloma Cell-Derived Runx2 Promotes Myeloma Progression and Bone-Homing

Mei Li, PhD, Timothy N Trotter, BS, Deniz Peker, MD, Patrick D Rowan, BS, Pan Qianying, MD, Suva J. Larry, PhD, Amjad Javed, PhD, Yang Yang, MD PhD
Journal: Blood
Blood (2014) 124 (21): 724.
https://doi.org/10.1182/blood.V124.21.724.724
Published: 2014
Journal Articles

Heparanase Promotes Myeloma Metastasis By Inducing EMT-like Features in Both Myeloma Cells and Endothelial Cells

Qianying Pan, MD, Patrick D Rowan, BS, Racquel Innis-Shelton, MD, Timothy N Trotter, BS, Mei Li, PhD, Deniz Peker, MD, Larry J Suva, PhD, Yang Yang, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2025.
https://doi.org/10.1182/blood.V124.21.2025.2025
Published: 2014
Journal Articles

Heparanase Expression Correlates with Bone Destruction in the Patients with Multiple Myeloma

Shi Wei, MD, Racquel Innis-Shelton, MD, Li Nan, Jian Ruan, MD, Rebecca S Sollie, Vishnu V B Reddy, MD, Yang Yang, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1813.
https://doi.org/10.1182/blood.V120.21.1813.1813
Published: 2012
Journal Articles

Runx2 Transcription Factor Regulates Heparanase-Induced Bone Resorption in Multiple Myeloma

Li Nan, Haiyan Chen, Jian Ruan, MD, Rebecca S Sollie, Cara Schafer, Francis T Crittenden, Anurag Purushothaman, PhD, Ralph D. Sanderson, PhD, Amjad Javed, PhD, Yang Yang, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 567.
https://doi.org/10.1182/blood.V120.21.567.567
Published: 2012
Journal Articles

A Heparin-Based Inhibitor of Heparanase Blocks Myeloma Growth In Vivo by Targeting the Tumor Microenvironment.

Yang Yang, MD, PhD, Telisha Swain, BA, Annamaria Naggi, PhD, Giangiacomo Torri, PhD, Benito Casu, PhD, Israel Vlodavsky, PhD, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2007) 110 (11): 1502.
https://doi.org/10.1182/blood.V110.11.1502.1502
Published: 2007
Journal Articles

Expression of Soluble Syndecan-1 or Heparanase by Myeloma Cells Enhances Levels of Angiogenic Growth Factors Present in Endothelial Cells.

Yang Yang, MD, PhD, Ashley Elizabeth Frith, Allison Theus, Veronica Macleod, MS, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2006) 108 (11): 3448.
https://doi.org/10.1182/blood.V108.11.3448.3448
Published: 2006
Journal Articles

Extracellular Endosulfatases (Sulfs) Inhibit Myeloma Tumor Growth In Vivo .

Yuemeng Dai, MD, PhD, Yang Yang, MD, PhD, Veronica MacLeod, MS, Xinping Yue, PhD, Alan C. Rapraeger, PhD, Zachary Shriver, PhD, Ganesh Venkataraman, PhD, Ram Sasisekharan, PhD, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2005) 106 (11): 3386.
https://doi.org/10.1182/blood.V106.11.3386.3386
Published: 2005
Journal Articles

Heparanase Upregulates Synthesis and Expression of Syndecan-1 (CD138) - A Novel Growth Regulatory Loop for Myeloma Tumors.

Yang Yang, MD, PhD, Veronica MacLeod, MS, Allison M. Theus, BS, Ralph D. Sanderson, PhD, Fenghuang Zhan, MD, PhD, John Shaughnessy, Jr., PhD
Journal: Blood
Blood (2005) 106 (11): 625.
https://doi.org/10.1182/blood.V106.11.625.625
Published: 2005
Journal Articles

Heparanase Promotes the Spontaneous Metastasis of Myeloma Cells to Bone.

Yang Yang, MD, PhD, Veronica MacLeod, MS, Manali Bendre, PhD, Yan Huang, Allison M. Theus, BA, Hua-Quan Miao, PhD, Paul Kussie, PhD, Shmuel Yaccoby, PhD, Joshua Epstein, DSc, Larry J. Suva, PhD, Thomas Kelly, PhD, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2004) 104 (11): 635.
https://doi.org/10.1182/blood.V104.11.635.635
Published: 2004