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Journal Articles

Updated Report of a Phase I/II Multicenter Study of Forodesine, a Purine Nucleoside Phosphorylase Inhibitor, in Japanese Patients with Relapsed Peripheral T-Cell Lymphoma

Blood (2017) 130 (Supplement 1): 4075.

https://doi.org/10.1182/blood.V130.Suppl_1.4075.4075

Published: 2017

Journal Articles

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

Shin Hasegawa, Tohru Fujiwara, MD PhD, Yoko Okitsu, MD PhD, Hiroki Kato, MD, PhD, Yuki Sato, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, Ritsuko Shimizu, MD PhD, Masayuki Yamamoto, MD PhD, Hideo Harigae, MD

Blood (2017) 130 (Supplement 1): 3781.

https://doi.org/10.1182/blood.V130.Suppl_1.3781.3781

Published: 2017

Journal Articles

Establishment and Characterization of in Vitro Model of X-Linked Sideroblastic Anemia

Kei Saito, Tohru Fujiwara, MD PhD, Shunsuke Hatta, MD PhD, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Yukio Nakamura, MD PhD, Hideo Harigae, MD

Blood (2017) 130 (Supplement 1): 171.

https://doi.org/10.1182/blood.V130.Suppl_1.171.171

Published: 2017

Journal Articles

Impaired Lysophosphatidic Acid Receptor 3 Signaling in Mesenchymal Stromal Cells Promotes Multiple Myeloma Progression through Cellular Senescence and Transdifferentiation into Tumor-Associated Fibroblasts

Masahiko Kanehira, DVM, PhD, Tohru Fujiwara, MD PhD, Shinji Nakajima, MD PhD, Yoko Okitsu, MD PhD, Yasushi Ohnishi, MD PhD, Noriko Fukuhara, MD PhD, Ryo Ichinohasama, MD PhD, Hideo Harigae, MD PhD

Blood (2015) 126 (23): 1764.

https://doi.org/10.1182/blood.V126.23.1764.1764

Published: 2015

Journal Articles

Two Phase I and Pharmacokinetic Studies of Darinaparsin (Organic Arsenic Compound) in Japanese and Korean Patients with Relapsed or Refractory (R/R) Peripheral T-Cell Lymphoma (PTCL)

Won-Seog Kim, MD PhD, Michinori Ogura, MD PhD, Toshiki Uchida, MD PhD, Naokuni Uike, MD, PhD, Yasunobu Abe, MD PhD, Kenichi Ishizawa, MD, PhD, Yoko Okitsu, MD PhD, Kensei Tobinai, MD PhD, Fumiko Nagahama, Yusuke Sonehara, Hirokazu Nagai, MD PhD

Blood (2015) 126 (23): 2714.

https://doi.org/10.1182/blood.V126.23.2714.2714

Published: 2015

Journal Articles

GATA-2 Regulates Dendritic Cell Differentiation

Koichi Onodera, MD, PhD, Tohru Fujiwara, MD, PhD, Yasushi Onishi, MD, PhD, Ari Itoh-Nakadai, PhD, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Kenichi Ishizawa, MD, PhD, Ritsuko Shimizu, MD, PhD, Masayuki Yamamoto, MD, PhD, Hideo Harigae, MD, PhD

Blood (2015) 126 (23): 2382.

https://doi.org/10.1182/blood.V126.23.2382.2382

Published: 2015

Journal Articles

Exploring the Potential Usefulness of 5-Aminolevulinic Acid for X-Linked Sideroblastic Anemia

Tohru Fujiwara, MD PhD, Ryoyu Niikuni, Koji Okamoto, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, MD PhD, Ryo Ichinohasama, MD PhD, Yukio Nakamura, MD, PhD, Tohru Tanaka, PhD, Hideo Harigae, MD PhD

Blood (2014) 124 (21): 215.

https://doi.org/10.1182/blood.V124.21.215.215

Published: 2014

Journal Articles

Impact of TET2 Deficiency on Iron Metabolism in Erythroblasts: A Potential Link to Ring Sideroblast Formation

Kyoko Inokura, MD, Tohru Fujiwara, MD PhD, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, MD PhD, Kazuya Shimoda, MD PhD, Hideo Harigae, MD PhD

Blood (2014) 124 (21): 750.

https://doi.org/10.1182/blood.V124.21.750.750

Published: 2014

Journal Articles

Exploring The Mechanisms To Reveal The Contribution Of LMO2 To The Transcriptional Regulation In Human Erythroblasts

AI Inoue, MD, Tohru Fujiwara, MD, PhD, Yoko Okitsu, MD, PhD, Noriko Fukuhara, MD, PhD, Yasushi Onishi, MD, PhD, Kenichi Ishizawa, MD, Hideo Harigae, MD, PhD

Blood (2013) 122 (21): 2178.

https://doi.org/10.1182/blood.V122.21.2178.2178

Published: 2013

Journal Articles

A Low-Molecular-Weight Compound K7174 Represses Hepcidin: Possible Therapeutic Strategy Against Anemia Of Chronic Disease

Tohru Fujiwara, MD, PhD, Takashi Ikeda, Yuki Nagasaka, Yoko Okitsu, MD, PhD, Noriko Fukuhara, MD, PhD, Yasushi Onishi, MD, PhD, Kenichi Ishizawa, MD, Ryo Ichinohasama, MD, PhD, Naohisa Tomosugi, MD, PhD, Hideo Harigae, MD, PhD

Blood (2013) 122 (21): 3436.

https://doi.org/10.1182/blood.V122.21.3436.3436

Published: 2013

Journal Articles

Elucidation of the Role of LMO2 (LIM-only protein 2) in Erythroid Cells

AI Inoue, MD, Tohru Fujiwara, MD, PhD, Yoko Okitsu, MD, PhD, Noriko Fukuhara, MD, PhD, Yasushi Onishi, MD, PhD, Kenichi Ishizawa, MD, PhD, Hideo Harigae, MD, PhD

Blood (2012) 120 (21): 3443.

https://doi.org/10.1182/blood.V120.21.3443.3443

Published: 2012

Journal Articles

Induction of Thymic Stromal Lymphopoietin in Mesenchymal Stem Cells by Interaction with Myeloma Cells

Shinji Nakajima, MD, PhD, Hiroto Ohguchi, MD, PhD, Yasushi Onishi, MD, PhD, Mayumi Kamata, MD, Tohru Fujiwara, MD, PhD, Yoko Okitsu, MD, PhD, Noriko Fukuhara, MD, PhD, Kenichi Ishizawa, MD, PhD, Hideo Harigae, MD, PhD

Blood (2012) 120 (21): 1825.

https://doi.org/10.1182/blood.V120.21.1825.1825

Published: 2012

Journal Articles

Regulation of Erythropoiesis by Histone Methyltransferase EZH2 Inhibitor 3-Deazaneplanocin A (DZNep)

Tohru Fujiwara, MD, PhD, Haruka Saitoh, Yoko Okitsu, MD, PhD, Noriko Fukuhara, MD, PhD, Yasushi Onishi, MD, PhD, Kenichi Ishizawa, MD, PhD, Ryo Ichinohasama, MD, PhD, Hideo Harigae, MD, PhD

Blood (2012) 120 (21): 982.

https://doi.org/10.1182/blood.V120.21.982.982

Published: 2012

Journal Articles

Decreased Expression of HOXB4 Gene in Aplastic Anemia; Regulatory Interaction with GATA-2,

Tohru Fujiwara, MD, PhD, Hisayuki Yokoyama, MD, PhD, Yoko Okitsu, MD, PhD, Mayumi Kamata, MD, Shinichi Fujimaki, PhD, Takashi Moriguchi, MD, PhD, Shinichiro Takahashi, MD, PhD, Emery H Bresnick, PhD, Hideo Harigae, MD, PhD

Blood (2011) 118 (21): 3436.

https://doi.org/10.1182/blood.V118.21.3436.3436

Published: 2011

Journal Articles

Exploring the Mechanism of ETO2-Dependent Transcriptional Regulation in Erythroid Cells

Alqadi Yarob Wael, Tohru Fujiwara, MD, PhD, Yoko Okitsu, MD, PhD, Yasushi Onishi, MD, PhD, Kenichi Ishizawa, MD, PhD, Hideo Harigae, MD, PhD

Blood (2011) 118 (21): 1307.

https://doi.org/10.1182/blood.V118.21.1307.1307

Published: 2011

Journal Articles

Phenotypic Changes of Hematopoietic Stem Cells and Stromal Cells by Aberrant Expression of GATA−2; Possible Role for the Development of Aplastic Anemia.

Yoko Okitsu, MD, Hideo Harigae, MD, Shinichiro Takahashi, MD, Naoko Minegishi, MD, Norio Suzuki, PhD, Junichi Kameoka, MD, Masayuki Yamamoto, MD, Takeshi Sasaki, MD

Blood (2006) 108 (11): 1289.

https://doi.org/10.1182/blood.V108.11.1289.1289

Published: 2006

Journal Articles

Induction of Adipocyte Differentiation and Reduction of Hematopoesis-Supporting Activity of Mouse Stromal Cells by Suppression of Transcription Factor GATA-2.

Yoko Okitsu, MD, Hideo Harigae, MD, Masanori Seki, MD, Toru Fujiwara, MD, Shinichiro Takahashi, MD, Hisayuki Yokoyama, MD, Junichi Kameoka, MD, Naoko Minegishi, MD, Takeshi Sasaki, MD

Blood (2005) 106 (11): 1392.

https://doi.org/10.1182/blood.V106.11.1392.1392

Published: 2005

Journal Articles

Functional Analysis of a Cation Transporter OCT6: A Mediator of the Cellular Influx of Adriamycin.

Yoko Okitsu, MD, Hideo Harigae, MD, Shinichiro Takahashi, MD, Shori Abe, MD, Mitsunori Okabe, MD, Michiaki Unno, MD, Takaaki Abe, MD, Mitsuo Kaku, MD, Takeshi Sasaki, MD

Blood (2004) 104 (11): 4374.

https://doi.org/10.1182/blood.V104.11.4374.4374

Published: 2004

Journal Articles

Decreased Expression of Stem Cell-Specific Genes in Aplastic Anemia; Possible Regulation of HOXB4 Gene by GATA-2.

Hisayuki Yokoyama, MD, Hideo Harigae, MD, Shinichiro Takahashi, MD, Yoko Okitsu, MD, Johji Yamamoto, MD, Yasuo Tohmiya, MD, Minami Fujiwara, MD, Kenichi Ishizawa, MD, Junichi Kameoka, MD, Naoko Minegishi, MD, Mitsuo Kaku, MD, Takeshi Sasaki, MD

Blood (2004) 104 (11): 2821.

https://doi.org/10.1182/blood.V104.11.2821.2821

Published: 2004

NARROW

Updated Report of a Phase I/II Multicenter Study of Forodesine, a Purine Nucleoside Phosphorylase Inhibitor, in Japanese Patients with Relapsed Peripheral T-Cell Lymphoma

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

Establishment and Characterization of in Vitro Model of X-Linked Sideroblastic Anemia

Impaired Lysophosphatidic Acid Receptor 3 Signaling in Mesenchymal Stromal Cells Promotes Multiple Myeloma Progression through Cellular Senescence and Transdifferentiation into Tumor-Associated Fibroblasts

Two Phase I and Pharmacokinetic Studies of Darinaparsin (Organic Arsenic Compound) in Japanese and Korean Patients with Relapsed or Refractory (R/R) Peripheral T-Cell Lymphoma (PTCL)

GATA-2 Regulates Dendritic Cell Differentiation

Exploring the Potential Usefulness of 5-Aminolevulinic Acid for X-Linked Sideroblastic Anemia

Impact of TET2 Deficiency on Iron Metabolism in Erythroblasts: A Potential Link to Ring Sideroblast Formation

Exploring The Mechanisms To Reveal The Contribution Of LMO2 To The Transcriptional Regulation In Human Erythroblasts

A Low-Molecular-Weight Compound K7174 Represses Hepcidin: Possible Therapeutic Strategy Against Anemia Of Chronic Disease

Elucidation of the Role of LMO2 (LIM-only protein 2) in Erythroid Cells

Induction of Thymic Stromal Lymphopoietin in Mesenchymal Stem Cells by Interaction with Myeloma Cells

Regulation of Erythropoiesis by Histone Methyltransferase EZH2 Inhibitor 3-Deazaneplanocin A (DZNep)

Decreased Expression of HOXB4 Gene in Aplastic Anemia; Regulatory Interaction with GATA-2,

Exploring the Mechanism of ETO2-Dependent Transcriptional Regulation in Erythroid Cells

Phenotypic Changes of Hematopoietic Stem Cells and Stromal Cells by Aberrant Expression of GATA−2; Possible Role for the Development of Aplastic Anemia.

Induction of Adipocyte Differentiation and Reduction of Hematopoesis-Supporting Activity of Mouse Stromal Cells by Suppression of Transcription Factor GATA-2.

Functional Analysis of a Cation Transporter OCT6: A Mediator of the Cellular Influx of Adriamycin.

Decreased Expression of Stem Cell-Specific Genes in Aplastic Anemia; Possible Regulation of HOXB4 Gene by GATA-2.

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American Society of Hematology

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American Society of Hematology

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