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Zhenbo Hu, MD, PhD
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Journal Articles

Small Molecular Modulators of Histone Demethylases Selectively Inhibits Growth of Hematopoietic Malignancies

Xin Xu, PhD, Wilhelm G Dirks, PhD, Hans G. Drexler, MD PhD, Zhenbo Hu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3941.
https://doi.org/10.1182/blood-2018-99-112376
Published: 2018
Journal Articles

A Small Molecular Agonist of Histone Demethylase KDM3B Selectively Represses MLL -Rearranged Acute Leukemia

Xin Xu, PhD, Wilhelm G Dirks, PhD, Hans G. Drexler, MD PhD, Zhenbo Hu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4682.
https://doi.org/10.1182/blood-2018-99-112018
Published: 2018
Journal Articles

The Mechanisms By Which Mutant-NPM1 Uncouples Differentiation from Proliferation Are Reversed By Several Drugs, Enabling Rational Multi-Component Non-Cytotoxic Differentiation Therapy

Xiaorong Gu, PhD, Quteba Ebrahem, MD, Reda Z. Mahfouz, MD PhD, Metis Hasipek, PhD, Francis Enane, PhD, Tomas Radivoyevitch, Nicolas Rapin, PhDMSc, Bartlomiej P. Przychodzen, MSc, Ramesh Balusu, PhD, Claudiu V Cotta, David Wald, MD PhD, Zhenbo Hu, MD PhD, Yosef Landesman, PhD, Maria Paola Martelli, MD PhD, Brunangelo Falini, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, PhD MD FACP, Babal K Jha, PhD, Yogenthiran Saunthararajah, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 878.
https://doi.org/10.1182/blood.V130.Suppl_1.878.878
Published: 2017
Journal Articles

The Mechanism By Which Mutant Nucleophosmin (NPM1) Creates Leukemic Self-Renewal Is Readily Reversed

Xiaorong Gu, PhD, Reda Z. Mahfouz, MD, PhD, Quteba Ebrahem, Francis Enane, Tomas Radivoyevitch, PhD, Michael J. Clemente, M.S., Bartlomiej P Przychodzen, MSc, Zhenbo Hu, MD PhD, Ramesh Balusu, PhD, Claudiu V. Cotta, MD, David N. Wald, MDPhD, Yosef Landesman, PhD, Maria Paola Martelli, MD PhD, Brunangelo Falini, Jaroslaw P Maciejewski, MD PhD FACP, Yogenthiran Saunthararajah, MD
Journal: Blood
Blood (2016) 128 (22): 444.
https://doi.org/10.1182/blood.V128.22.444.444
Published: 2016
Journal Articles

A Specific Mechanism By Which NPM1 mutations Impede Myeloid Differentiation Also Explains The Link With DNMT3A Mutation

Xiaorong Gu, PhD, Reda Z Mahfouz, MD/PhD, Francis Enane, MS, Zhenbo Hu, MD, PhD, Michael J. Clemente, Bartlomiej P Przychodzen, PhD, Mikkael A. Sekeres, MD, MS, Anjali S. Advani, MD, Matt Kalaycio, MD, Jaroslaw P. Maciejewski, MD, PhD, Yogen Saunthararajah, M.D.
Journal: Blood
Blood (2013) 122 (21): 1254.
https://doi.org/10.1182/blood.V122.21.1254.1254
Published: 2013
Journal Articles

Extra-Nuclear Dislocation of PU.1 but Not CEBPA by Mutated NPM1 in AML Explains Lineage-Associations, ATRA Therapeutic Potential and DNMT3A Secondary Mutation.

Xiaorong Gu, PhD, Reda Z Mahfouz, MD/PhD, Zhenbo Hu, MD, PhD, Yogenthiran Saunthararajah, MD
Journal: Blood
Blood (2012) 120 (21): 2427.
https://doi.org/10.1182/blood.V120.21.2427.2427
Published: 2012
Journal Articles

UTX Mutations and Epigenetic Changes In MDS/MPN and Related Myeloid Malignancies

Hadrian Szpurka, PhD, MSc, Anna M Jankowska, MSc, Bartlomiej Przychodzen, BSc, Zhenbo Hu, MD, PhD, Yogen Saunthararajah, MD, Michael A McDevitt, MD, PhD, Jaroslaw P Maciejewski, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 121.
https://doi.org/10.1182/blood.V116.21.121.121
Published: 2010