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Journal Articles

Blocking Lysosomal Two-Pore Channel 2 Function Inhibits Proliferation of Multidrug Resistant Leukemia Cells and Sensitizes Them to Vincristine Treatment

Martin Müller, MSc, Franz Geisslinger, Susanne Gerndt, Ramona Schütz, Yu-Kai Chao, Franz Bracher, Christian Grimm, Angelika Vollmar, Karin Bartel

Blood (2019) 134 (Supplement_1): 2081.

https://doi.org/10.1182/blood-2019-128195

Published: 2019

Journal Articles

Comprehensive Analysis of Genotype and Prior Exposures in Therapy-Related Myeloid Neoplasms (t-MNs)

Veronica A Guerra, MD, Yan Yuanqing, PhD, Joanne Hsu, BS, Feng Wang, PhD, Mansour Alfayez, MD, Kiyomi Morita, MD, Xingzhi Song, PhD, Courtney D. DiNardo, MD MSc, Marina Y Konopleva, MD PhD, Gautam M. Borthakur, MD, Guillermo Montalban Bravo, MD, Jianhua Zhang, PhD, Latasha Little, BS, Curtis Gumbs, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, Andrew Futreal, PhD, Koichi Takahashi, MD

Blood (2019) 134 (Supplement_1): 458.

https://doi.org/10.1182/blood-2019-127498

Published: 2019

Journal Articles

A Safety Study of the Addition of Omacetaxine to the Standard-of-Care Induction Regimen of Cytarabine and Idarubicin in Newly-Diagnosed AML Patients

Sonia Christian, MD, Kelley E. Kozma, DO, Stephanie Barath, Ardaman Shergill, MD, Damiano Rondelli, MD, David Peace, MD, Santosh L. Saraf, MD, Annie Lee Oh, MD, Karen Sweiss, PharmD, Irum Khan, MBBS, Pritesh Patel, MD, Arkadiusz Dudek, MD PhD, John G. Quigley

Blood (2018) 132 (Supplement 1): 5218.

https://doi.org/10.1182/blood-2018-99-111412

Published: 2018

Journal Articles

Reversal of Chemoresistance in Leukemia Cells Using Synthetic Bisbenzylisoquinoline Derivatives

Martin Müller, Susanne Gerndt, Anja Arner, Yu-Kai Chao, Linus Schömig, Carina Atzberger, Martin Biel, Franz Bracher, Angelika Vollmar, Vera Binder, MD, Marco Keller, Christian Grimm, Karin Bartel

Blood (2018) 132 (Supplement 1): 3504.

https://doi.org/10.1182/blood-2018-99-111651

Published: 2018

Journal Articles

The Novel Berbamine Derivative, Cbbm, Downregulates c-Myc to Block Diffuse Large B-Cell Lymphoma Cell Maintenance

Lei Zhang, MD, Rongzhen Xu, PhD, Ling Li, PhD, Xiaoying Zhao, MD, Jinwen Huang, MD

Blood (2018) 132 (Supplement 1): 212.

https://doi.org/10.1182/blood-2018-99-112006

Published: 2018

Journal Articles

Narciclasine Display Preferential Pre-Clinical Activity Against KSHV-Associated Primary Effusion Lymphoma By Targeting MYC Via NF-κB

Ramakrishnan Gopalakrishnan, PhD, Hittu Matta, PhD, Sunju Choi, PhD, Preet M. Chaudhary, MD PhD

Blood (2017) 130 (Supplement 1): 2807.

https://doi.org/10.1182/blood.V130.Suppl_1.2807.2807

Published: 2017

Journal Articles

An Evaluation of the Cytotoxic Effect of the Natural Product Aaptamine Against t(4;11) Leukemias

Chandrima Sinha, PhD, John Bowling, PhD, Aman Seth, MS, Bensheng Ju, PhD, Bhaskar Kahali, PhD, Mark Hamann, PhD, Lea C. Cunningham, MD

Blood (2016) 128 (22): 1624.

https://doi.org/10.1182/blood.V128.22.1624.1624

Published: 2016

Journal Articles

Inhibition of CML Stem Cells with an Alkaloid That Reduces β-Catenin

Shawnya J. Michaels, MS,MBA, Ngoc DeSouza, PhDCandidate, Yi Shan, MD, Shaoguang Li, MD PhD, Saira Bates, MBA

Blood (2016) 128 (22): 1882.

https://doi.org/10.1182/blood.V128.22.1882.1882

Published: 2016

Journal Articles

Lycorine Downregulates HMGB1 to Inhibit Autophagy and Enhances Bortezomib Activity in Multiple Myeloma

Mridul Roy, Long Liang, Xiaojuan Xiao, Yuanliang Peng, Yuhao Luo, Weihua Zhou, Ji Zhang, Lugui Qiu, Shuaishuai Zhang, Feng Liu, Xiuli An, MD PhD, Mao Ye, Wen Zhou, PhD, Jing Liu, PhD

Blood (2016) 128 (22): 3265.

https://doi.org/10.1182/blood.V128.22.3265.3265

Published: 2016

Journal Articles

Securinine Targets Cancer Cells through an Irak and JNK Dependent Pathway

Kalpana Gupta, PhD, Gary Parizher, BS, Marcos De Lima, MD, David N. Wald, MDPhD

Blood (2015) 126 (23): 3791.

https://doi.org/10.1182/blood.V126.23.3791.3791

Published: 2015

Journal Articles

Microenvironmental Stromal Cells Rescue CLL Cells from Apoptosis Via Hypoxia That Can be Targeted Therapeutically

Irina Idler, PhD, Deyan Yosifov, PhD, Nupur Bhattacharya, PhD, Michaela Reichenzeller, PhD, Viola Meyer-Pannwitt, Daria Ezerina, Annika Scheffold, M.Sc., Sabrina Kugler, PhD, Tobias Dick, PhD, Hartmut Dohner, MD, Stephan Stilgenbauer, MD, Daniel Mertens, PhD

Blood (2015) 126 (23): 4140.

https://doi.org/10.1182/blood.V126.23.4140.4140

Published: 2015

Journal Articles

PCYT1A in MYC-Driven Lymphoma: Role on Aberrant Choline Metabolism and Therapeutic Targeting By Berberine

Jie Xiong, PhD, Li Wang, MDPhD, Weili Zhao, MDPhD

Blood (2015) 126 (23): 698.

https://doi.org/10.1182/blood.V126.23.698.698

Published: 2015

Journal Articles

Dendrogenin_A : A Natural Liver X Receptor Modulator for the Treatment of Acute Myeloid Leukemia

Christian Recher, MDPhD, Marion David, PhD, Philippe de Medina, PhD, Cécile Bize, PhD, Nizar Serhan, PhD, Michael R Paillasse, PhD, Estelle Saland, Emmanuel Noguer, Julia Cherier, PhD, Cécile Demur, MDPhD, Clément Larrue, Fabienne de Toni, PhD, François Vergez, VMD-PhD, Jean-emmanuel Sarry, PhD, Sandrine Silvente-Poirot, PhD, Marc Poirot, PhD

Blood (2014) 124 (21): 3767.

https://doi.org/10.1182/blood.V124.21.3767.3767

Published: 2014

Journal Articles

Bringing an Old Drug to a New Treatment Strategy in Treating FLT-ITD AML - Combination of Homoharringtonine and Sorafenib

Eric S.K. Ho, Stephen Sze Yuen Lam, Cheuk Him Man, PhD, Chae Yin Cher, Yok Lam Kwong, MD, Anskar Y.H. Leung, MD

Blood (2014) 124 (21): 3610.

https://doi.org/10.1182/blood.V124.21.3610.3610

Published: 2014

Journal Articles

Role Of Folate Receptor Targeted Therapy In Multiple Myeloma

Sonali Panchabhai, MBBS, Katalin Kelemen, MD, PhD, Sinto Sebastian Chirackal, PhD, BSc, MSc, Rafael Fonseca, M.D.

Blood (2013) 122 (21): 4436.

https://doi.org/10.1182/blood.V122.21.4436.4436

Published: 2013

Journal Articles

Homoharringtonine In Combination With Cytarabine and Etoposide For Induction Therapy In Patients With De Novo Acute Myelogenous Leukemia

Jingsong He, MD, PhD, Li Li, M.Med, Jingjing Zhu, Yi Zhao, PhD, Wenjun Wu, M.Med, Yanlong Zheng, Gaofeng Zheng, M.Med, Weiyan Zheng, M.D., Xiaoli Zhu, He Huang, MD, PhD., Xiujin Ye, M.D. Ph.D.

Blood (2013) 122 (21): 5006.

https://doi.org/10.1182/blood.V122.21.5006.5006

Published: 2013

Journal Articles

Activity Of Omacetaxine Mepesuccinate Against Ponatinib Resistant Philadelphia Chromosome Positive Leukemia Cells

Seiichi Okabe, MD, Tetsuzo Tauchi, MD, Yuko Tanaka, MD, Seiichiro Katagiri, MD, Toshihiko Kitahara, MD, Kazuma Ohyashiki, MD, PhD

Blood (2013) 122 (21): 3840.

https://doi.org/10.1182/blood.V122.21.3840.3840

Published: 2013

Journal Articles

Comparative Efficacy of Homoharringtonine Plus Cytarabine and Decitabine in Patients with MDS/AML

Yuejian Liu, M.D., Feili Chen, M.D., Xutao Guo, M.D., Pengcheng Shi, M.D., Jie Zha, M.D., Zhiping Fan, Fen Huang, M.D., Bing Xu, M.D. PhD

Blood (2012) 120 (21): 4340.

https://doi.org/10.1182/blood.V120.21.4340.4340

Published: 2012

Journal Articles

Lycorine Modulates the Expression of p21 Via a p53-Independent Pathway in HL-60 Cells

Jing Liu, Shu-Ling Wang, Lin Fang, Mao Ye, Zhi-Wei Sun, Lv Li, Zi Wang, Hui-Wen Yan, Sai-Qun Luo, Hui-Yong Chen, Xiuli An, MD, PhD, Wei-Xin Hu

Blood (2011) 118 (21): 4297.

https://doi.org/10.1182/blood.V118.21.4297.4297

Published: 2011

Journal Articles

Agelastatin A (AgA), a Marine Sponge Derived Alkaloid, Inhibits Wnt/Beta-Catenin Signaling and Selectively Induces Apoptosis in Chronic Lymphocytic Leukemia Independently of p53

Michael Y. Choi, MD, Johanna Melo Cardenas, BSc, Desheng Lu, MD, PhD, Jian Yu, PhD, E. Paige Stout, PhD, Raymond P. Wu, Ph.D., John M Horton, B.S., Allison Gomez, Julio A. Diaz-Perez, M.D., M.S., Dennis A. Carson, M.D., Tadeusz F. Molinski, PhD, Thomas J. Kipps, M.D., Ph.D, Januario E. Castro, M.D.

Blood (2011) 118 (21): 1786.

https://doi.org/10.1182/blood.V118.21.1786.1786

Published: 2011

NARROW

Blocking Lysosomal Two-Pore Channel 2 Function Inhibits Proliferation of Multidrug Resistant Leukemia Cells and Sensitizes Them to Vincristine Treatment

Comprehensive Analysis of Genotype and Prior Exposures in Therapy-Related Myeloid Neoplasms (t-MNs)

A Safety Study of the Addition of Omacetaxine to the Standard-of-Care Induction Regimen of Cytarabine and Idarubicin in Newly-Diagnosed AML Patients

Reversal of Chemoresistance in Leukemia Cells Using Synthetic Bisbenzylisoquinoline Derivatives

The Novel Berbamine Derivative, Cbbm, Downregulates c-Myc to Block Diffuse Large B-Cell Lymphoma Cell Maintenance

Narciclasine Display Preferential Pre-Clinical Activity Against KSHV-Associated Primary Effusion Lymphoma By Targeting MYC Via NF-κB

An Evaluation of the Cytotoxic Effect of the Natural Product Aaptamine Against t(4;11) Leukemias

Inhibition of CML Stem Cells with an Alkaloid That Reduces β-Catenin

Lycorine Downregulates HMGB1 to Inhibit Autophagy and Enhances Bortezomib Activity in Multiple Myeloma

Securinine Targets Cancer Cells through an Irak and JNK Dependent Pathway

Microenvironmental Stromal Cells Rescue CLL Cells from Apoptosis Via Hypoxia That Can be Targeted Therapeutically

PCYT1A in MYC-Driven Lymphoma: Role on Aberrant Choline Metabolism and Therapeutic Targeting By Berberine

Dendrogenin_A : A Natural Liver X Receptor Modulator for the Treatment of Acute Myeloid Leukemia

Bringing an Old Drug to a New Treatment Strategy in Treating FLT-ITD AML - Combination of Homoharringtonine and Sorafenib

Role Of Folate Receptor Targeted Therapy In Multiple Myeloma

Homoharringtonine In Combination With Cytarabine and Etoposide For Induction Therapy In Patients With De Novo Acute Myelogenous Leukemia

Activity Of Omacetaxine Mepesuccinate Against Ponatinib Resistant Philadelphia Chromosome Positive Leukemia Cells

Comparative Efficacy of Homoharringtonine Plus Cytarabine and Decitabine in Patients with MDS/AML

Lycorine Modulates the Expression of p21 Via a p53-Independent Pathway in HL-60 Cells

Agelastatin A (AgA), a Marine Sponge Derived Alkaloid, Inhibits Wnt/Beta-Catenin Signaling and Selectively Induces Apoptosis in Chronic Lymphocytic Leukemia Independently of p53

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American Society of Hematology

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ASH Publications

American Society of Hematology

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