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Journal Articles

Mebendazole Mediates Its Anti-Leukemic Effects By Proteasomal Degradation of GLI Transcription Factors Via Inhibition of HSP70/90-Chaperone Activity in Acute Myeloid Leukemia in a Preclinical and Clinical Setting

Fabian Freisleben, Hauke Stamm, PhD, Jana Muschhammer, Vanessa Thaden, Franziska Modemann, MD, Alexander Krispien, Franziska Brauneck, Jasmin Wellbrock, PhD, Walter Fiedler, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5050.
https://doi.org/10.1182/blood-2019-129973
Published: 2019
Journal Articles

Mebendazole Exerts Potent Anti-Leukemic Effects By Downregulating Protein Levels of Hedgehog Transcription Factors GLI1 and GLI2

Fabian Freisleben, Hauke Stamm, PhD, Jana Muschhammer, Alexander Krispien, Vanessa Thaden, Jasmin Wellbrock, PhD, Walter Fiedler, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5145.
https://doi.org/10.1182/blood-2018-99-118189
Published: 2018
Journal Articles

Pyrvinium Pamoate Overcomes Cabozantinib-Resistance of FLT3 -ITD AML Cells through Modulating the Mitochondria Functions and Signaling Pathways

Yu-Hsuan Fu, BS, Wen-Hui Lu, MS, Pei-Qi Lan, MS, Chung-Yi Hu, PhD, Chien-Yuan Chen, MD, PhD, Da-Liang Ou, PhD, Hwei-Fang Tien, MD, PhD, Liang-In Lin, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4683.
https://doi.org/10.1182/blood-2018-99-118476
Published: 2018
Journal Articles

High-Throughput Screen Identification of Albendazole As a Novel Repurposed Drug in Acute Myeloid Leukaemia

Kyle B Matchett, PhD, Ivan V Grishagin, PhD, Laura Kettyle, PhD, Catriona Dowling, PhD, Triona Ni Chonghaile, PhD, Ken I Mills, BSc PhDFRCPath, Alexander Thompson, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5062.
https://doi.org/10.1182/blood.V130.Suppl_1.5062.5062
Published: 2017
Journal Articles

The Salicylamide Derivative, Niclosamide, Inhibits CREB Function in Acute Myeloid Leukemia Cells In Vitro and In Vivo

Hee-Don Chae, PhD, Nick Cox, PhD, Xiaohua Zhang, Jae Wook Lee, MD PhD, David Morgens, Michael C Bassik, PhD, Mark Smith, PhD, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1647.
https://doi.org/10.1182/blood.V128.22.1647.1647
Published: 2016
Journal Articles

Identification of Small Molecules Selectively Targeting Leukemic Stem Cells within Their Stromal Niche

Alissa R. Kahn, MD, Kimberly A. Hartwell, PhD, Peter G. Miller, PhD, Benjamin L. Ebert, MD, PhD, Todd R. Golub, MD, Malcolm A.S. AS Moore
Journal: Blood
Blood (2012) 120 (21): 413.
https://doi.org/10.1182/blood.V120.21.413.413
Published: 2012
Journal Articles

Levamisole Adulterated In Cocaine Causing Agranulocytosis, Vasculopathy and Acquired Protein S Deficiency

Irene Dy, Venkata Pokuri, M.D., Eric O. Gamboa, MD, John Olichney, MD
Journal: Blood
Blood (2010) 116 (21): 1421.
https://doi.org/10.1182/blood.V116.21.1421.1421
Published: 2010
Journal Articles

Nocodazole Induces Multiple Myeloma Cell Death and Reduces Tumor Growth through Sequential Microtubular Network Damage and C-Jun N-Terminal Kinase-Mediated Bcl-2 Phosphorylation.

Rentian Feng, PhD, Huihui Ma, Noriyoshi Kurihara, PhD, DDS, Shirong Li, PhD, Judy A Ziegler, Markus Y Mapara, MD, PhD, G. David Roodman, MD, PhD, Suzanne Lentzsch, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 296.
https://doi.org/10.1182/blood.V114.22.296.296
Published: 2009
Journal Articles

Nocodazole Induces Myeloma Cell Death by Disrupting the Microtubular Network, Resulting in G2/M Arrest

Rentian Feng, PhD, Jorge A Rios, MD, Markus Mapara, MD, PD, Suzanne Lentzsch, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3673.
https://doi.org/10.1182/blood.V112.11.3673.3673
Published: 2008