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Journal Articles

PRMT5 Inhibition Drives Therapeutic Vulnerability to BCL-2 Inhibition with Venetoclax and Provides Rationale for Combination Therapy in Mantle Cell Lymphoma

Fiona Brown, BS, Yang Zhang, PhD, Claire Hinterschied, Alexander Prouty, BS, Shelby Sloan, BS, JoBeth Helmig-Mason, Msc, Ji Hyun Chung, PhD, Kris Vaddi, PhD, Selina Chen-Kiang, PhD, Maurizio Di Liberto, PhD, Lapo Alinari, MD PhD, Peggy Scherle, PhD, Rosa Lapalombella, PhD, Jihye Paik, PhD, Robert A Baiocchi, MD PhD

Blood (2019) 134 (Supplement_1): 302.

https://doi.org/10.1182/blood-2019-130797

Published: 2019

Journal Articles

Modulation of CD81 By Epigenetic Drug Combination Sensitizes Acute Lymphoblastic Leukemia Via Decreased BTK Signaling

Anthony Quagliano, BS, Anilkumar Gopalakrishnapillai, PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc

Blood (2019) 134 (Supplement_1): 2628.

https://doi.org/10.1182/blood-2019-129198

Published: 2019

Journal Articles

TP53 Deficient/Mutant AMLs Are Resistant to Individual BH3 Mimetics: High Efficacy of Combined Inhibition of Bcl-2 and Mcl-1

Bing Z Carter, PhD, Po Yee Mak, Steven M. Kornblau, MD, Wenjing Tao, Yuki Nishida, MD PhD, Vivian Ruvolo, MS, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 1271.

https://doi.org/10.1182/blood-2019-124826

Published: 2019

Journal Articles

Arsenic Trioxide Induces Apoptosis and Regulatory Functions of Plasmacytoid Dendritic Cells

Yishan Ye, MD, Laure Ricard, MD, Nicolas Stocker, MD, Baptiste Lamarthée, PhD, Frédéric De Vassoigne, Eolia Brissot, MDPhD, Arsène Mekinian, MDPhD, Mohamad Mohty, MD PhD, Béatrice Gaugler, PhD, Florent Malard, MDPhD

Blood (2018) 132 (Supplement 1): 514.

https://doi.org/10.1182/blood-2018-99-110717

Published: 2018

Journal Articles

Ubiquitin-Activating Enzyme E1 Inhibition Caused Acute Leukemia Cell Apoptosis By Affecting CHOP Pathway

Ju Bai, PhD, Aili He, MD, Jianli Wang, MD, Yun Yang, MD, Ying Shen, MD, Yuandong Feng, MD, Yan Xu

Blood (2018) 132 (Supplement 1): 2784.

https://doi.org/10.1182/blood-2018-99-118162

Published: 2018

Journal Articles

The Gain of the Short Arm of Chromosome 2 (2p+) Induces XPO1 Overexpression and Drug Resistance in Chronic Lymphocytic Leukemia

Blood (2015) 126 (23): 492.

https://doi.org/10.1182/blood.V126.23.492.492

Published: 2015

Journal Articles

Effect of RNAi-Mediated Knockdown of MCM7 on Human Leukemia Cells and Its Mechanism

Liang Tian, MD, Baoan Chen, PhD Professor, Juan Liu, Jian Cheng, PhD, Guohua Xia

Blood (2015) 126 (23): 5554.

https://doi.org/10.1182/blood.V126.23.5554.5554

Published: 2015

Journal Articles

Mechanisms Underlying the Synergistic Interaction of Filanesib with Pomalidomide and Dexamethasone (FPD) in Multiple Myeloma

Susana Hernández-García, Laura San-Segundo, Lorena González-Méndez, Montserrat Martín-Sánchez, Luis A Corchete, Teresa Paíno, Ana Alicia López-Iglesias, Esperanza Macarena Algarín, Mercedes Garayoa, Brian Tunquist, Norma C Gutierrez, Maria-Victoria Mateos, MD PhD, Enrique M Ocio

Blood (2015) 126 (23): 1801.

https://doi.org/10.1182/blood.V126.23.1801.1801

Published: 2015

Journal Articles

Filanesib Primarily Initiates the Apoptotic Program By Activating Bax through a Calpain-Dependent Mechanism

Susana Hernández-García, Lorena González-Méndez, Irena Misiewicz-Krzeminska, Esperanza Macarena Algarín, Ana Alicia López-Iglesias, Laura San-Segundo, Montserrat Martín-Sánchez, Teresa Paíno, Norma C Gutierrez, Mercedes Garayoa, Brian Tunquist, Maria-Victoria Mateos, Enrique M Ocio

Blood (2015) 126 (23): 5353.

https://doi.org/10.1182/blood.V126.23.5353.5353

Published: 2015

Journal Articles

Carfilzomib, a Second-Generation Proteasome Inhibitor, In Combination With The Btk Inhibitor Ibrutinib As a Novel Therapeutic Regimen For Treating Double Hit DLBCL

Erin M Dominici, Elyse R Lopez, Muychi T Vang, Archito T. Tamayo, MS, Zhishuo Ou, MD, Alex Rollo, Liang Zhang, MD, PhD, Jack Wang, Lauren M Strickland, Michael Wang, MD, Richard J. Ford, MD, PhD, Lan V Pham, PhD, Christopher J. Kirk, Ph.D

Blood (2013) 122 (21): 1834.

https://doi.org/10.1182/blood.V122.21.1834.1834

Published: 2013

Journal Articles

Actin and Myosin-II Inhibition Increase Megakaryocyte Proplatelet Formation Through a Caspase Dependent Mechanism

Mauro P. Avanzi, MD, Oluwasijibomi E. Oluwadara, W. Beau Mitchell, MD

Blood (2013) 122 (21): 3652.

https://doi.org/10.1182/blood.V122.21.3652.3652

Published: 2013

Journal Articles

Pro-Apoptotic Effect of An Anti-CD37 Scfv-Fc Fusion Protein, in Combination with the Anti-CD20 Antibody, Ofatumumab, on Tumor Cells From B-Cell Malignancies

Piotr Smolewski, Robak Pawel, Barbara Cebula-Obrzut, Malgorzata Misiewicz, Aleksandra Jeske, Agata Majchrzak, Scott Stromatt, MD, Tadeusz Robak

Blood (2011) 118 (21): 1662.

https://doi.org/10.1182/blood.V118.21.1662.1662

Published: 2011

Journal Articles

Platelet Apoptosis and Agonist Mediated Activation In Myelodysplastic Syndromes

Nora V. Butta, Raquel de Paz, Mónica Martín Salces, Ihosvany Fernández Bello, Elena G. Arias Salgado, Mayte Álvarez Román, Isabel Rivas, Ana Rodríguez de la Rúa, Víctor Jiménez-Yuste

Blood (2010) 116 (21): 1866.

https://doi.org/10.1182/blood.V116.21.1866.1866

Published: 2010

Journal Articles

High Pro-Apoptotic Effects of 17-Allylamino-17-Demethoxy Geldanamycin (17-AAG) In Philadelphia Acute Lymphoblastic Leukemia (Ph+ ALL)

Emmanuelle Tavernier-Tardy, Pascale Flandrin, Francoise Solly, Jérôme Cornillon, Karine Augeul-Meunier, Jean-Louis Stephan, Denis Guyotat, Lydia Campos, MD, PhD

Blood (2010) 116 (21): 3226.

https://doi.org/10.1182/blood.V116.21.3226.3226

Published: 2010

Journal Articles

Study on the Relevance of Inducing Apoptosis and Reversal Effect of Nilotinib In Combination with Tet on Multidrug Reststahoe of K562/A02 Cell Line

Bao-An Chen, MD, PhD, Ting-yun Cui, Jia-hua Ding, Chong Gao, Xue-yun Shan, Jian Cheng, Wen Bao, Yue-jiao Zhong, Feng Gao, Guo-hua Xia, Anita Schmitt, Michael Schmitt

Blood (2010) 116 (21): 4951.

https://doi.org/10.1182/blood.V116.21.4951.4951

Published: 2010

Journal Articles

MK886 Induced Apoptosis in HL-60 Cells Via Inhibition mPGES-1 Expression and Down-Regulation Prostaglandin E 2 Synthesize.

Yiqing Li, Songmei Yin, MD, Shuangfeng Xie, Danian Nie, Liping Ma, Xiuju Wang, Yudan Wu

Blood (2009) 114 (22): 4824.

https://doi.org/10.1182/blood.V114.22.4824.4824

Published: 2009

Journal Articles

Mitochondrial-Mediated Apoptosis in Lymphoma by the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographolis Paniculata.

Shuo Yang, PhD, Andrew M Evens, DO, MSc, Savita Bhalla, PhD, Sheila Prachand, M.S., Amareshwar Singh, PhD, Leo I. Gordon, MD

Blood (2009) 114 (22): 2710.

https://doi.org/10.1182/blood.V114.22.2710.2710

Published: 2009

Journal Articles

Activity of Anti-Tumor Endoribonucleases, Onconase (ranpirnase) and R-Amphinase in Chronic Lymphocytic Leukemia

Piotr Smolewski, Anna Linke-Szewczyk, Barbara Cebula, Kuslima Shogen, Wojciech Ardelt, Zbigniew Darzynkiewicz, Tadeusz Robak, MD, PhD

Blood (2008) 112 (11): 4205.

https://doi.org/10.1182/blood.V112.11.4205.4205

Published: 2008

Journal Articles

Research of Apoptosis Induction by the Application of Magnetic Nanoparticle of Fe 3 O 4 Loaded with Daunorubicin and 5-Bromotetrandrine in K562/A02 Leukemic Cells

Blood (2008) 112 (11): 5060.

https://doi.org/10.1182/blood.V112.11.5060.5060

Published: 2008

Journal Articles

Fatty Acid Synthase and Diffuse Large B Cell Lymphoma

Shahab Uddin, PhD, Azhar Hussain, MBBS, Prashant Bavi, MD, Khawla Al-Kuraya, MD

Blood (2008) 112 (11): 4979.

https://doi.org/10.1182/blood.V112.11.4979.4979

Published: 2008

NARROW

PRMT5 Inhibition Drives Therapeutic Vulnerability to BCL-2 Inhibition with Venetoclax and Provides Rationale for Combination Therapy in Mantle Cell Lymphoma

Modulation of CD81 By Epigenetic Drug Combination Sensitizes Acute Lymphoblastic Leukemia Via Decreased BTK Signaling

TP53 Deficient/Mutant AMLs Are Resistant to Individual BH3 Mimetics: High Efficacy of Combined Inhibition of Bcl-2 and Mcl-1

Arsenic Trioxide Induces Apoptosis and Regulatory Functions of Plasmacytoid Dendritic Cells

Ubiquitin-Activating Enzyme E1 Inhibition Caused Acute Leukemia Cell Apoptosis By Affecting CHOP Pathway

The Gain of the Short Arm of Chromosome 2 (2p+) Induces XPO1 Overexpression and Drug Resistance in Chronic Lymphocytic Leukemia

Effect of RNAi-Mediated Knockdown of MCM7 on Human Leukemia Cells and Its Mechanism

Mechanisms Underlying the Synergistic Interaction of Filanesib with Pomalidomide and Dexamethasone (FPD) in Multiple Myeloma

Filanesib Primarily Initiates the Apoptotic Program By Activating Bax through a Calpain-Dependent Mechanism

Carfilzomib, a Second-Generation Proteasome Inhibitor, In Combination With The Btk Inhibitor Ibrutinib As a Novel Therapeutic Regimen For Treating Double Hit DLBCL

Actin and Myosin-II Inhibition Increase Megakaryocyte Proplatelet Formation Through a Caspase Dependent Mechanism

Pro-Apoptotic Effect of An Anti-CD37 Scfv-Fc Fusion Protein, in Combination with the Anti-CD20 Antibody, Ofatumumab, on Tumor Cells From B-Cell Malignancies

Platelet Apoptosis and Agonist Mediated Activation In Myelodysplastic Syndromes

High Pro-Apoptotic Effects of 17-Allylamino-17-Demethoxy Geldanamycin (17-AAG) In Philadelphia Acute Lymphoblastic Leukemia (Ph+ ALL)

Study on the Relevance of Inducing Apoptosis and Reversal Effect of Nilotinib In Combination with Tet on Multidrug Reststahoe of K562/A02 Cell Line

MK886 Induced Apoptosis in HL-60 Cells Via Inhibition mPGES-1 Expression and Down-Regulation Prostaglandin E 2 Synthesize.

Mitochondrial-Mediated Apoptosis in Lymphoma by the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographolis Paniculata.

Activity of Anti-Tumor Endoribonucleases, Onconase (ranpirnase) and R-Amphinase in Chronic Lymphocytic Leukemia

Research of Apoptosis Induction by the Application of Magnetic Nanoparticle of Fe 3 O 4 Loaded with Daunorubicin and 5-Bromotetrandrine in K562/A02 Leukemic Cells

Fatty Acid Synthase and Diffuse Large B Cell Lymphoma

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American Society of Hematology

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American Society of Hematology

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